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Pathways
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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
DNA damage response +     
DNA metabolic process +     
base-excision repair, AP site formation +   
base-excision repair, gap-filling  
broken chromosome clustering  
chromosomal 5-methylcytosine DNA demethylation pathway +   
DNA biosynthetic process +   
DNA catabolic process +   
DNA double-strand break processing +   
DNA integration  
DNA modification +   
DNA protection  
DNA recombination +   
DNA repair +   
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA repair-dependent chromatin remodeling  
DNA replication +   
DNA replication initiation +   
DNA replication termination +   
DNA replication, Okazaki fragment processing +   
DNA strand displacement +   
DNA strand elongation +   
DNA strand invasion +   
DNA strand resection involved in replication fork processing +   
DNA topological change  
DNA-templated DNA replication maintenance of fidelity +   
formation of extrachromosomal circular DNA +   
G-quadruplex DNA formation  
gap filling involved in double-strand break repair via nonhomologous end joining 
heteroduplex formation +  
intrinsic apoptotic signaling pathway in response to DNA damage +   
lagging strand initiation 
maintenance of DNA repeat elements +   
meiotic DNA double-strand break formation +   
mitochondrial DNA metabolic process +   
negative regulation of DNA metabolic process +   
nucleotide-excision repair, DNA gap filling  
plastid DNA metabolic process +  
positive regulation of DNA metabolic process +   
regulation of DNA metabolic process +   
removal of nonhomologous ends +  
resolution of DNA recombination intermediates +   
signal transduction in response to DNA damage +   
SOS response 
telomere maintenance +   
telomere maintenance in response to DNA damage +   

Synonyms
Xrefs: Reactome:R-HSA-73894 "DNA Repair" ;   Wikipedia:DNA_repair
Definition Sources: PMID:11563486

paths to the root