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ONTOLOGY REPORT - ANNOTATIONS

Term:mismatch repair
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Accession:GO:0006298 term browser browse the term
Definition:A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
Synonyms:exact_synonym: MMR
 narrow_synonym: long patch mismatch repair system
 related_synonym: MutS/MutL/MutH pathway;   mismatch repair, MutL-like pathway
 alt_id: GO:0006300
 xref: Wikipedia:DNA_mismatch_repair


show annotations for term's descendants           Sort by:
mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 involved_in IBA
ISO		 PMID:21873635
UniProtKB:P43246 (PMID:11809771), (PMID:14636568), (PMID:9788596)		 RGD PMID:9788596 PMID:11809771 PMID:14636568 PMID:21873635 RGD:13792537 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000002
PMID:21873635
GO_REF:0000107
UniProtKB:P43246|UniProtKB:P52701 (PMID:23603115)
MGI:1857946|MGI:1858054|MGI:1930998 (MGI:1197799|PMID:9500552), (MGI:1203882|PMID:9560238), (MGI:1332740|PMID:10096563), (MGI:1339254|PMID:10359802), (MGI:1353727|PMID:10657972), (MGI:1354996|PMID:10747038), (MGI:1859717|PMID:10851078), (MGI:1933705|PMID:11313994), (MGI:3607956|PMID:16204034), (MGI:3691360|PMID:10429667), (MGI:3692242|PMID:16728433), (MGI:81371|PMID:8674118)		 InterPro
Ensembl
RGD		 PMID:8674118 PMID:9500552 PMID:9560238 PMID:10096563 PMID:10359802 More... GO_REF:0000002 GO_REF:0000107 MGI:1197799 MGI:1203882 MGI:1332740 MGI:1339254 MGI:1353727 MGI:1354996 MGI:1859717 MGI:1933705 MGI:3607956 MGI:3691360 MGI:3692242 MGI:81371, RGD:13792537 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mlh3 mutL homolog 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:104288|MGI:2384218 (MGI:3607956|PMID:16204034)
PMID:21873635		 RGD PMID:16204034 PMID:21873635 MGI:3607956, RGD:13792537 NCBI chr 6:104,881,483...104,917,686
Ensembl chr 6:104,881,483...104,917,728 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000104
PMID:21873635
(PMID:7923193), (PMID:9677427)
UniProtKB:P40692|UniProtKB:P52701 (PMID:11555625), (PMID:23603115)
MGI:109519|MGI:1857940|MGI:1858055|MGI:2151801|MGI:2389314|MGI:2680817 (MGI:1096207|PMID:9288110), (MGI:1275866|PMID:9697842), (MGI:1350445|PMID:10581038), (MGI:1861016|PMID:10874005), (MGI:1889760|PMID:10992298), (MGI:1926519|PMID:11046134), (MGI:2176101|PMID:11890935), (MGI:2388857|PMID:12531017), (MGI:3029112|PMID:14744764), (MGI:3692242|PMID:16728433), (MGI:3703647|PMID:17331550), (MGI:5464025|PMID:23071719), (MGI:74950|PMID:7628020), (MGI:82395|PMID:8706033), (MGI:87767|PMID:9157971), (MGI:894568|PMID:9244348)		 UniProt
RGD		 PMID:7628020 PMID:7923193 PMID:8706033 PMID:9157971 PMID:9244348 More... GO_REF:0000104 MGI:1096207 MGI:1275866 MGI:1350445 MGI:1861016 MGI:1889760 MGI:1926519 MGI:2176101 MGI:2388857 MGI:3029112 MGI:3692242 MGI:3703647 MGI:5464025 MGI:74950 MGI:82395 MGI:87767 MGI:894568, RGD:13792537 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 acts_upstream_of_or_within
involved_in		 ISO MGI:101816|MGI:1343961|MGI:1858056|MGI:88039 (MGI:1353715|PMID:10706084), (MGI:2154151|PMID:11691815), (MGI:3692242|PMID:16728433)
(PMID:8782829), (PMID:9677427)		 RGD PMID:8782829 PMID:9677427 PMID:10706084 PMID:11691815 PMID:16728433 MGI:1353715 MGI:2154151 MGI:3692242 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh4 mutS homolog 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:242,785,392...242,844,609
Ensembl chr 2:242,792,661...242,843,487 		JBrowse link
G Msh5 mutS homolog 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within
involved_in		 ISO
IBA
IMP		 MGI:109519|MGI:1858014|MGI:2151803|MGI:3653701|MGI:88039 (MGI:1100204|PMID:9390556), (MGI:2154151|PMID:11691815), (MGI:2388851|PMID:12370835), (MGI:3053495|PMID:15324697), (MGI:3692242|PMID:16728433), (MGI:5464025|PMID:23071719)
PMID:21873635
UniProtKB:P40692|UniProtKB:P43246 (PMID:23603115)
(PMID:10871409), (PMID:23622243), (PMID:8782829)		 RGD PMID:8782829 PMID:9390556 PMID:10871409 PMID:11691815 PMID:12370835 More... MGI:1100204 MGI:2154151 MGI:2388851 MGI:3053495 MGI:3692242 MGI:5464025, RGD:13792537, RGD:2292505 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Mutyh mutY DNA glycosylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO
IBA		 (PMID:11005803)
PMID:21873635		 RGD PMID:11005803 PMID:21873635 RGD:13792537 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1857948 (MGI:1197799|PMID:9500552)
PMID:21873635		 RGD PMID:9500552 PMID:21873635 MGI:1197799, RGD:13792537 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10871409), (PMID:23709753), (PMID:9618520)
PMID:21873635
MGI:1353455|MGI:1857946|MGI:1857947 (MGI:1197799|PMID:9500552), (MGI:1339254|PMID:10359802), (MGI:1933705|PMID:11313994), (MGI:3607956|PMID:16204034), (MGI:3691360|PMID:10429667), (MGI:3692242|PMID:16728433), (MGI:5464025|PMID:23071719)		 RGD PMID:9500552 PMID:9618520 PMID:10359802 PMID:10429667 PMID:10871409 More... MGI:1197799 MGI:1339254 MGI:1933705 MGI:3607956 MGI:3691360 MGI:3692242 MGI:5464025, RGD:13792537 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5499950|PMID:23603115)
PMID:21873635
(PMID:23603115)		 RGD PMID:23603115 PMID:21873635 MGI:5499950, RGD:13792537 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Rpa1 replication protein A1 involved_in ISO (PMID:9430682) RGD PMID:9430682 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9430682)		 UniProt
RGD		 PMID:9430682 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 involved_in IBA
ISO		 PMID:21873635
(PMID:9430682)		 RGD PMID:9430682 PMID:21873635 RGD:13792537 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpa3l1 replication protein A3 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase involved_in ISO (PMID:23622243) RGD PMID:23622243 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor involved_in ISO
IEA		 (PMID:26300262)
(MGI:5705200|PMID:26300262)
GO_REF:0000107		 RGD
Ensembl		 PMID:26300262 GO_REF:0000107 MGI:5705200 NCBI chr20:32,818,219...32,929,577
Ensembl chr20:32,844,951...32,929,600 		JBrowse link
positive regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26221039)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26221039 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:15014079) RGD PMID:15014079 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Prkcg protein kinase C, gamma involved_in ISO (PMID:15808853) RGD PMID:15808853 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
regulation of mismatch repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in ISO
IEA		 (PMID:11017067)
GO_REF:0000107		 RGD
Ensembl		 PMID:11017067 GO_REF:0000107 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular response to stimulus 8778
        cellular response to stress 2097
          DNA damage response 830
            DNA repair 525
              mismatch repair 24
                meiotic mismatch repair + 0
                mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication + 1
                negative regulation of mismatch repair 0
                positive regulation of mismatch repair 3
                regulation of mismatch repair + 4
Path 2
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      cellular metabolic process 10124
        cellular aromatic compound metabolic process 5773
          nucleobase-containing compound metabolic process 5539
            nucleic acid metabolic process 4966
              DNA metabolic process 993
                DNA repair 525
                  mismatch repair 24
                    meiotic mismatch repair + 0
                    mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication + 1
                    negative regulation of mismatch repair 0
                    positive regulation of mismatch repair 3
                    regulation of mismatch repair + 4
paths to the root