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transforming growth factor-beta superfamily mediated signaling pathway - Ontology Report - Rat Genome Database

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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:transforming growth factor-beta superfamily mediated signaling pathway
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Accession:PW:0000329 term browser browse the term
Definition:The TGF-beta superfamily of growth factors regulates a broad spectrum of processes such as angiogenesis, embryonic development, cell differentiation, proliferation and wound healing. Binding to two types of serine/threonine receptors and activation of Smad proteins is a common theme. However, ligand-receptor interaction and the identity of the activated Smad protein(s) appear to be member-specific.
Synonyms:related_synonym: Signaling by TGF-beta family members;   TGF-beta superfamily mediated signaling pathway


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activin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 ISO RGD
PID
PMID:12770730 PID:200029 RGD:1559169 NCBI chr10:43,139,396...43,281,024
Ensembl chr10:43,139,528...43,281,177
JBrowse link
G ACVR1B activin A receptor type 1B ISO RGD PMID:12770730 PMID:17040568 RGD:1559169 RGD:2315948 NCBI chr11:48,120,765...48,166,520
Ensembl chr11:48,145,003...48,166,813
JBrowse link
G ACVR2A activin A receptor type 2A ISO RGD PMID:12770730 RGD:1559169 NCBI chr10:33,223,902...33,311,257
Ensembl chr10:33,224,099...33,307,720
JBrowse link
G ACVR2B activin A receptor type 2B ISO RGD PMID:12770730 RGD:1559169 NCBI chr15:923,222...962,438 JBrowse link
G ACVRL1 activin A receptor like type 1 ISO PID
RGD
PMID:12770730 PID:200029 RGD:1559169 NCBI chr11:48,063,099...48,091,705
Ensembl chr11:48,082,135...48,093,630
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO PID PID:200029 NCBI chr 2:55,170,816...55,195,380 JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:12770730 RGD:1559169 NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606
JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:12770730 RGD:1559169 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527
JBrowse link
altered transforming growth factor-beta Smad dependent signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD2 SMAD family member 2 ISO RGD PMID:17613544 PMID:18662538 RGD:2306282 RGD:2308865 NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606
JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:17613544 PMID:18772397 RGD:2306282 RGD:5490966 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527
JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:17613544 PMID:18662538 PMID:18772397 PMID:19506583 RGD:2306282 RGD:2308865 RGD:5490965 RGD:5490966 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478
JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:18662538 RGD:2308865 NCBI chr18:31,993,543...32,024,088
Ensembl chr18:31,993,681...32,024,850
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:17613544 PMID:18313409 RGD:2299005 RGD:2306282 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:17613544 PMID:18313409 RGD:2299005 RGD:2306282 NCBI chr12:40,272,507...40,321,740
Ensembl chr12:40,276,916...40,297,372
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:17613544 PMID:18313409 PMID:18662538 PMID:18772397 PMID:19506583 RGD:2299005 RGD:2306282 RGD:2308865 RGD:5490965 RGD:5490966 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711
JBrowse link
Bone morphogenetic proteins signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein ISO PID PID:200144 NCBI chr15:2,809,234...2,818,382
Ensembl chr15:2,809,028...2,817,514
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor ISO PID PID:200144 NCBI chr 9:28,279,479...28,284,825
Ensembl chr 9:28,279,523...28,285,937
JBrowse link
G BMP2 bone morphogenetic protein 2 ISO PID
RGD
PMID:16361357 PID:200144 RGD:1580077 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901
JBrowse link
G BMP4 bone morphogenetic protein 4 ISO RGD
PID
PMID:18985159 PID:200144 RGD:11553861 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO PID PID:200144 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382
JBrowse link
G BMP7 bone morphogenetic protein 7 ISO PID PID:200144 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A ISO PID PID:200144 NCBI chr 9:44,944,463...45,108,832
Ensembl chr 9:44,941,460...45,027,275
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B ISO PID PID:200144
G BMPR2 bone morphogenetic protein receptor type 2 ISO RGD
PID
PMID:16361357 PID:200144 RGD:1580077 NCBI chr10:88,103,442...88,302,578
Ensembl chr10:88,106,072...88,303,734
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr12:64,859,301...64,865,676
Ensembl chr12:64,860,958...64,863,544
JBrowse link
G CHRD chordin ISO PID PID:200144 NCBI chr15:5,030,618...5,040,399
Ensembl chr15:5,030,457...5,039,991
JBrowse link
G CHRDL1 chordin like 1 ISO PID PID:200144 NCBI chr  X:98,490,291...98,611,811
Ensembl chr  X:98,489,874...98,611,951
JBrowse link
G CTDSP1 CTD small phosphatase 1 ISO PID PID:200144 NCBI chr10:104,291,494...104,298,982
Ensembl chr10:104,293,073...104,299,258
JBrowse link
G CTDSP2 CTD small phosphatase 2 ISO PID PID:200144 NCBI chr11:53,733,041...53,759,809
Ensembl chr11:53,736,699...53,742,750
JBrowse link
G CTDSPL CTD small phosphatase like ISO PID PID:200144 NCBI chr15:1,418,855...1,536,527
Ensembl chr15:1,418,848...1,536,457
JBrowse link
G FST follistatin ISO PID PID:200144 NCBI chr 4:49,773,646...49,780,343
Ensembl chr 4:49,773,980...49,780,333
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO PID PID:200144 NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239
JBrowse link
G HJV hemojuvelin BMP co-receptor ISO PID PID:200144 NCBI chr20:12,730,106...12,735,230
Ensembl chr20:12,730,912...12,735,255
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO PID PID:200144 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200144 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325
JBrowse link
G NOG noggin ISO PID PID:200144 NCBI chr16:36,816,783...36,818,693
Ensembl chr16:36,817,476...36,818,174
JBrowse link
G NUP214 nucleoporin 214 ISO PID PID:200144 NCBI chr12:6,905,047...7,014,907
Ensembl chr12:6,903,096...7,014,887
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A ISO PID PID:200144 NCBI chr24:37,474,371...37,522,956
Ensembl chr24:37,506,914...37,516,414
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO PID PID:200144 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO PID PID:200144
G RGMA repulsive guidance molecule BMP co-receptor a ISO PID PID:200144 NCBI chr29:11,592,929...11,638,955
Ensembl chr29:11,592,604...11,638,860
JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b ISO PID PID:200144 NCBI chr23:2,339,567...2,368,239
Ensembl chr23:2,341,856...2,369,294
JBrowse link
G SKI SKI proto-oncogene ISO PID PID:200144 NCBI chr20:129,243,033...129,324,162
Ensembl chr20:129,242,445...129,324,138
JBrowse link
G SLC39A13 solute carrier family 39 member 13 ISO RGD PMID:18985159 RGD:11553861 NCBI chr 1:17,899,349...17,907,165
Ensembl chr 1:17,899,030...17,905,850
JBrowse link
G SMAD1 SMAD family member 1 ISO PID
RGD
PMID:16361357 PMID:18985159 PID:200144 RGD:11553861 RGD:1580077 NCBI chr 7:92,047,273...92,123,451
Ensembl chr 7:92,079,914...92,123,429
JBrowse link
G SMAD4 SMAD family member 4 ISO PID PID:200144 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478
JBrowse link
G SMAD5 SMAD family member 5 ISO RGD
PID
PMID:16361357 PMID:18985159 PID:200144 RGD:11553861 RGD:1580077 NCBI chr23:38,877,294...38,926,208
Ensembl chr23:38,877,315...38,921,202
JBrowse link
G SMAD6 SMAD family member 6 ISO PID PID:200144 NCBI chr26:16,760,117...16,841,286
Ensembl chr26:16,759,260...16,840,240
JBrowse link
G SMAD7 SMAD family member 7 ISO PID PID:200144 NCBI chr18:31,993,543...32,024,088
Ensembl chr18:31,993,681...32,024,850
JBrowse link
G SMAD9 SMAD family member 9 ISO RGD
PID
PMID:16361357 PID:200144 RGD:1580077 NCBI chr 3:15,369,119...15,444,599
Ensembl chr 3:15,372,933...15,405,836
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 ISO PID PID:200144 NCBI chr28:14,019,733...14,141,588
Ensembl chr28:14,019,968...14,141,795
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 ISO PID PID:200144 NCBI chr16:56,615,171...56,728,239 JBrowse link
G SOSTDC1 sclerostin domain containing 1 ISO PID PID:200144 NCBI chr21:41,645,884...41,651,360
Ensembl chr21:41,647,079...41,652,093
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO PID PID:200144 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO PID PID:200144 NCBI chr13:22,234,736...22,312,985
Ensembl chr13:22,234,012...22,282,562
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO PID PID:200144
G ZFYVE16 zinc finger FYVE-type containing 16 ISO PID PID:200144 NCBI chr 4:74,579,573...74,644,331
Ensembl chr 4:74,579,982...74,644,784
JBrowse link
transforming growth factor-beta signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 ISO RGD PMID:29069575 RGD:151347449 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627
JBrowse link
G PARK7 Parkinsonism associated deglycase ISO RGD PMID:29069575 RGD:151347449 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434
JBrowse link
G TSC2 TSC complex subunit 2 ISO RGD PMID:15066998 RGD:1580519 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682
JBrowse link
transforming growth factor-beta Smad dependent signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO PID PID:200227 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385
JBrowse link
G ATF3 activating transcription factor 3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr25:16,910,312...16,922,598 JBrowse link
G AXIN1 axin 1 ISO PID PID:200227 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor ISO PID PID:200227 NCBI chr 9:28,279,479...28,284,825
Ensembl chr 9:28,279,523...28,285,937
JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha ISO PID PID:200227 NCBI chr23:52,829,438...52,899,428
Ensembl chr23:52,829,350...52,899,375
JBrowse link
G CAV1 caveolin 1 ISO PID PID:200227 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627
JBrowse link
G CCN2 cellular communication network factor 2 ISO PID PID:200227 NCBI chr13:41,613,838...41,617,010
Ensembl chr13:41,613,798...41,617,651
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832
JBrowse link
G CREBBP CREB binding protein ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943
JBrowse link
G CTNNB1 catenin beta 1 ISO PID PID:200227 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
G DACT2 dishevelled binding antagonist of beta catenin 2 ISO PID PID:200227 NCBI chr13:96,141,847...96,152,677 JBrowse link
G DAXX death domain associated protein ISO PID PID:200227 NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071
JBrowse link
G DCN decorin ISO RGD PMID:12809600 RGD:2298922 NCBI chr11:86,552,392...86,590,229
Ensembl chr11:86,551,072...86,586,891
JBrowse link
G DYNLRB1 dynein light chain roadblock-type 1 ISO PID PID:200227 NCBI chr 2:38,813,852...38,839,905
Ensembl chr 2:38,825,574...38,839,903
JBrowse link
G EIF2A eukaryotic translation initiation factor 2A ISO PID PID:200227 NCBI chr15:40,112,926...40,146,629
Ensembl chr15:40,111,878...40,146,554
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO PID
RGD
PMID:12809600 PID:200227 RGD:2298922 NCBI chr 2:55,170,816...55,195,380 JBrowse link
G FOXH1 forkhead box H1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 8:138,685,137...138,688,451
Ensembl chr 8:138,685,626...138,687,144
JBrowse link
G FOXO1 forkhead box O1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707
JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725
JBrowse link
G FOXO4 forkhead box O4 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr  X:60,893,711...60,901,134
Ensembl chr  X:60,893,526...60,902,844
JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200227 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO PID PID:200227 NCBI chr 2:38,671,170...38,808,621
Ensembl chr 2:38,701,396...38,805,005
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO PID PID:200227 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase ISO PID PID:200227 NCBI chr18:21,326,276...21,683,817
Ensembl chr18:21,327,567...21,683,905
JBrowse link
G OCLN occludin ISO PID PID:200227 NCBI chr 4:65,581,943...65,641,516
Ensembl chr 4:65,582,460...65,644,787
JBrowse link
G PARD6A par-6 family cell polarity regulator alpha ISO PID PID:200227 NCBI chr 5:59,781,890...59,783,990 JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200227
G PML PML nuclear body scaffold ISO PID PID:200227 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO PID PID:200227 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO PID PID:200227
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO PID PID:200227 NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280
JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta ISO PID PID:200227 NCBI chr 8:28,903,074...28,930,300
Ensembl chr 8:28,903,240...28,930,376
JBrowse link
G PPP2R2A protein phosphatase 2 regulatory subunit Balpha ISO PID PID:200227 NCBI chr 8:24,390,751...24,485,657
Ensembl chr 8:24,390,781...24,487,195
JBrowse link
G RHOA ras homolog family member A ISO PID PID:200227 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704
JBrowse link
G RNF111 ring finger protein 111 ISO PID PID:200227 NCBI chr26:24,416,946...24,528,989
Ensembl chr26:24,416,093...24,528,862
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO PID PID:200227 NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr 2:78,819,189...79,082,491
Ensembl chr 2:78,819,194...78,924,495
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr17:26,679,386...26,807,812
Ensembl chr17:26,683,175...26,807,319
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO RGD PMID:16322555 PMID:18061509 RGD:2302137 RGD:5143919 NCBI chr20:107,769,244...107,802,154
Ensembl chr20:107,736,683...107,802,307
JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200227 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610
JBrowse link
G SKIL SKI like proto-oncogene ISO PID PID:200227 NCBI chr15:19,022,167...19,059,117
Ensembl chr15:19,022,017...19,057,004
JBrowse link
G SMAD2 SMAD family member 2 ISO PID
RGD
PMID:12809600 PMID:16959941 PMID:18684975 PID:200227 RGD:1599906 RGD:2298922 RGD:2302517 NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606
JBrowse link
G SMAD3 SMAD family member 3 ISO RGD
PID
PMID:12702545 PMID:12809600 PMID:16891311 PID:200227 RGD:1299323 RGD:1625706 RGD:2298922 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527
JBrowse link
G SMAD4 SMAD family member 4 ISO PID
RGD
PMID:12809600 PMID:16959941 PID:200227 RGD:1599906 RGD:2298922 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478
JBrowse link
G SMAD7 SMAD family member 7 ISO PID
RGD
PMID:12809600 PID:200227 RGD:2298922 NCBI chr18:31,993,543...32,024,088
Ensembl chr18:31,993,681...32,024,850
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 ISO PID
RGD
PMID:12809600 PID:200227 RGD:2298922 NCBI chr28:14,019,733...14,141,588
Ensembl chr28:14,019,968...14,141,795
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 ISO RGD
PID
PMID:12809600 PID:200227 RGD:2298922 NCBI chr16:56,615,171...56,728,239 JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200227 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 ISO PID PID:200227 NCBI chr14:52,266,197...52,487,111
Ensembl chr14:52,262,416...52,487,112
JBrowse link
G STRAP serine/threonine kinase receptor associated protein ISO PID PID:200227 NCBI chr11:15,790,449...15,812,964
Ensembl chr11:15,790,798...15,813,585
JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO PID PID:200227 NCBI chr19:21,971,362...22,004,289 JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 ISO PID PID:200227 NCBI chr13:22,234,736...22,312,985
Ensembl chr13:22,234,012...22,282,562
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD
PID
PMID:15109563 PID:200227 RGD:2298921 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD
PID
PMID:15109563 PID:200227 RGD:2298921 NCBI chr25:11,163,651...11,259,868
Ensembl chr25:11,163,100...11,258,470
JBrowse link
G TGFB3 transforming growth factor beta 3 ISO RGD
PID
PMID:12809600 PID:200227 RGD:2298922 NCBI chr24:53,203,593...53,227,483
Ensembl chr24:53,203,301...53,227,325
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD
PID
PMID:12809600 PMID:18684975 PID:200227 RGD:2298922 RGD:2302517 NCBI chr12:40,272,507...40,321,740
Ensembl chr12:40,276,916...40,297,372
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO PID
RGD
PMID:12809600 PMID:14729511 PMID:18684975 PID:200227 RGD:1579921 RGD:2298922 RGD:2302517 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO PID
RGD
PMID:12809600 PID:200227 RGD:2298922 NCBI chr20:41,353,182...41,565,357
Ensembl chr20:41,353,325...41,565,343
JBrowse link
G TGFBRAP1 transforming growth factor beta receptor associated protein 1 ISO PID PID:200227 NCBI chr14:8,900,342...8,963,107
Ensembl chr14:8,898,587...8,942,148
JBrowse link
G WWP1 WW domain containing E3 ubiquitin protein ligase 1 ISO PID PID:200227 NCBI chr 8:81,529,520...81,651,478 JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO PID PID:200227
G YAP1 Yes1 associated transcriptional regulator ISO PID PID:200227 NCBI chr 1:93,479,478...93,605,340
Ensembl chr 1:93,479,135...93,606,808
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon ISO PID PID:200227 NCBI chr16:1,031,840...1,086,950
Ensembl chr16:1,035,250...1,087,013
JBrowse link
G ZFYVE16 zinc finger FYVE-type containing 16 ISO PID PID:200227 NCBI chr 4:74,579,573...74,644,331
Ensembl chr 4:74,579,982...74,644,784
JBrowse link
G ZFYVE9 zinc finger FYVE-type containing 9 ISO PID
RGD
PMID:12809600 PID:200227 RGD:2298922 NCBI chr20:80,596,744...80,734,195
Ensembl chr20:80,598,435...80,740,159
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    signaling pathway 1919
      growth factor signaling pathway 370
        transforming growth factor-beta superfamily mediated signaling pathway 103
          Bone morphogenetic proteins signaling pathway + 43
          Nodal signaling pathway 0
          activin signaling pathway 8
          altered transforming growth factor-beta superfamily mediated signaling pathway + 7
          transforming growth factor-beta signaling pathway + 67
paths to the root