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Pathways
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Term:
Parent Terms Term With Siblings Child Terms
activin signaling pathway  
altered transforming growth factor-beta superfamily mediated signaling pathway +    
Bone morphogenetic proteins signaling pathway +   
Nodal signaling pathway 
transforming growth factor-beta signaling pathway +    
The transforming growth factor-beta (TGF-beta) signaling pathway regulates numerous cellular processes such as proliferation, differentiation, migration and cell death. The SMAD-dependent pathway represents the core signaling cascade mediated by the TGF-beta superfamily. Mutations in the TGF-beta family are responsible for a number of human diseases.

Synonyms
Related Synonyms: Signaling by TGF-beta Receptor Complex ;   transforming growth factor beta receptor signaling pathway
Definition Sources: GO:0007179, PMID:15130563, PMID:16678165, PubMed:TIBS, 2004, v29 (5), p265-273, Reactome:R-HSA-170834

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