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Ontology Browser

Term:
transforming growth factor-beta superfamily mediated signaling pathway (PW:0000329)
Annotations: Rat: (150) Mouse: (153) Human: (152) Chinchilla: (104) Bonobo: (104) Dog: (104) Squirrel: (104) Pig: (104) Naked Mole-rat: (101) Green Monkey: (103)     Pathway Diagram Browser
Parent Terms Term With Siblings Child Terms
altered growth factor signaling pathway +    
angiopoietin signaling pathway  
epidermal growth factor/neuregulin signaling pathway +    
fibroblast growth factor signaling pathway +   
Gas6 - Axl signaling axis  
insulin-like growth factor signaling pathway +   
neurotrophic factor signaling pathway +   
platelet-derived growth factor signaling pathway +   
scatter factor/hepatocyte growth factor signaling pathway +    
Stem Cell Factor signaling pathway 
transforming growth factor-beta superfamily mediated signaling pathway +    
The TGF-beta superfamily of growth factors regulates a broad spectrum of processes such as angiogenesis, embryonic development, cell differentiation, proliferation and wound healing. Binding to two types of serine/threonine receptors and activation of Smad proteins is a common theme. However, ligand-receptor interaction and the identity of the activated Smad protein(s) appear to be member-specific.
vascular endothelial growth factor signaling pathway +    

Synonyms
Related Synonyms: Signaling by TGF-beta family members ;   TGF-beta superfamily mediated signaling pathway
Definition Sources: KEGG:map04350, PMID:15473857, Reactome:R-HSA-9006936

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