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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:Bone morphogenetic proteins signaling pathway
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Accession:PW:0000330 term browser browse the term
Definition:The bone morphogenetic proteins (BMP) are related to TGF-beta and activins and are members of the TGF-beta superfamily. The BMP signaling pathway plays important roles in induction and patterning of the mesoderm. BMP pathway cross-talks to other pathways such as TGF-beta, Wnt, MAPK, Notch, JAK-STAT and others.
Synonyms:related_synonym: BMP signaling pathway;   Signaling by BMP


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Bone morphogenetic proteins signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein ISO PID PID:200144 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO PID PID:200144 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bmp2 bone morphogenetic protein 2 IMP
ISO		 PID
RGD		 PMID:16361357 PID:200144, RGD:1580077 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO PID
RGD		 PMID:18985159 PID:200144, RGD:11553861 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO PID PID:200144 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO PID PID:200144 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO PID PID:200144 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO PID PID:200144 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IMP
ISO		 PID
RGD		 PMID:16361357 PID:200144, RGD:1580077 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783 		JBrowse link
G Chrd chordin ISO PID PID:200144 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Chrdl1 chordin-like 1 ISO PID PID:200144 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921 		JBrowse link
G Ctdsp1 CTD small phosphatase 1 ISO PID PID:200144 NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297 		JBrowse link
G Ctdsp2 CTD small phosphatase 2 ISO PID PID:200144 NCBI chr 7:62,805,398...62,825,306
Ensembl chr 7:62,805,658...62,825,302 		JBrowse link
G Ctdspl CTD small phosphatase like ISO PID PID:200144 NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117 		JBrowse link
G Fst follistatin ISO PID PID:200144 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO PID PID:200144 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200144 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hjv hemojuvelin BMP co-receptor ISO PID PID:200144 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO PID PID:200144 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO PID PID:200144 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Nog noggin ISO PID PID:200144 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nup214 nucleoporin 214 ISO PID PID:200144 NCBI chr 3:15,255,111...15,340,568
Ensembl chr 3:15,255,119...15,340,568 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A ISO PID PID:200144 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha ISO PID PID:200144 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO PID PID:200144 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a ISO PID PID:200144 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Rgmb repulsive guidance molecule BMP co-receptor b ISO PID PID:200144 NCBI chr 1:56,766,598...56,792,396
Ensembl chr 1:56,767,850...56,792,425 		JBrowse link
G Ski Ski proto-oncogene ISO PID PID:200144 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Slc39a13 solute carrier family 39 member 13 ISO RGD PMID:18985159 RGD:11553861 NCBI chr 3:77,039,411...77,047,528
Ensembl chr 3:77,037,565...77,049,226 		JBrowse link
G Smad1 SMAD family member 1 IMP
ISO		 PID
RGD		 PMID:16361357 PMID:18985159 PID:200144, RGD:1580077, RGD:11553861 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad4 SMAD family member 4 ISO PID PID:200144 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad5 SMAD family member 5 IMP
ISO		 PID
RGD		 PMID:16361357 PMID:18985159 PID:200144, RGD:1580077, RGD:11553861 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smad6 SMAD family member 6 ISO PID PID:200144 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Smad7 SMAD family member 7 ISO PID PID:200144 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smad9 SMAD family member 9 IMP
ISO		 PID
RGD		 PMID:16361357 PID:200144, RGD:1580077 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO PID PID:200144 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 ISO PID PID:200144 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488 		JBrowse link
G Sostdc1 sclerostin domain containing 1 ISO PID PID:200144 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
G Stambp Stam binding protein ISS RGD PMID:11483516 RGD:1549422 NCBI chr 4:116,055,563...116,083,563
Ensembl chr 4:116,056,057...116,080,543 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO PID PID:200144 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO PID PID:200144 NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756 		JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO PID PID:200144 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 ISO PID PID:200144 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      signaling pathway pertinent to development 536
        Bone morphogenetic proteins signaling pathway 44
          altered bone morphogenetic protein signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      growth factor signaling pathway 523
        transforming growth factor-beta superfamily mediated signaling pathway 150
          Bone morphogenetic proteins signaling pathway 44
            altered bone morphogenetic protein signaling pathway 0
paths to the root