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ONTOLOGY REPORT - ANNOTATIONS

Term:cholesterol transfer activity
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Accession:GO:0120020 term browser browse the term
Definition:Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms:exact_synonym: cholesterol carrier activity
 narrow_synonym: intermembrane cholesterol transfer activity
 broad_synonym: cholesterol transporter activity
 alt_id: GO:0017127
 xref: Reactome:R-HSA-1454928 "ABCG4 may mediate cholesterol efflux";   Reactome:R-HSA-216723 "4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane";   Reactome:R-HSA-265443 "NPC1L1-mediated cholesterol uptake";   Reactome:R-HSA-265545 "NPC1L1-mediated phytosterol uptake";   Reactome:R-HSA-266082 "ABCG1-mediated transport of intracellular cholesterol to the cell surface";   Reactome:R-HSA-5682111 "Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane";   Reactome:R-HSA-8951850 "TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane"
 never_in_taxon: NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
cholesterol transfer activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 enables ISO (PMID:12084722)
(PMID:15520449)		 RGD PMID:12084722 PMID:15520449 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 enables ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 contributes_to ISO UniProtKB:Q99PE8 (PMID:14504269)
(MGI:2681374|PMID:14504269)		 RGD PMID:14504269 MGI:2681374 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 contributes_to ISO
IBA		 UniProtKB:Q9DBM0 (PMID:14504269)
(MGI:2681374|PMID:14504269)
GO_REF:0000033		 RGD
GO_Central		 PMID:14504269 GO_REF:0000033 MGI:2681374 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Apoa1 apolipoprotein A1 contributes_to
enables		 IDA
ISO
IEA
IBA		 (PMID:9651324)
(PMID:15464323)
GO_REF:0000107
GO_REF:0000033
(PMID:15269218)		 RGD
Ensembl
GO_Central		 PMID:9651324 PMID:15269218 PMID:15464323 PMID:11773045 PMID:1537840 GO_REF:0000033 GO_REF:0000107, RGD:1298673, RGD:1626399 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 contributes_to
enables		 IDA
ISO
IBA		 (PMID:9651324)
GO_REF:0000033		 RGD
GO_Central		 PMID:9651324 PMID:1537840 GO_REF:0000033, RGD:1626399 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 enables IEA
ISO
IBA		 GO_REF:0000107
(PMID:1935934)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:1935934 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoa5 apolipoprotein A5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Apob apolipoprotein B enables ISO
IEA
IBA		 (PMID:15797858)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15797858 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoe apolipoprotein E enables IBA
ISO		 GO_REF:0000033
(PMID:15269218)		 GO_Central
RGD		 PMID:15269218 GO_REF:0000033 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Gramd1a GRAM domain containing 1A enables IEA
ISS
ISO
IBA		 GO_REF:0000107
GO_REF:0000024
(MGI:6242147|PMID:30220461)
GO_REF:0000033		 Ensembl
UniProt
RGD
GO_Central		 PMID:30220461 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:6242147 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336 		JBrowse link
G Gramd1b GRAM domain containing 1B enables ISO
IBA		 (MGI:6242147|PMID:30220461)
GO_REF:0000033		 RGD
GO_Central		 PMID:30220461 GO_REF:0000033 MGI:6242147 NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925 		JBrowse link
G Gramd1c GRAM domain containing 1C enables ISO (MGI:6242147|PMID:30220461) RGD PMID:30220461 MGI:6242147 NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570 		JBrowse link
G Mttp microsomal triglyceride transfer protein enables IDA
ISO		 PMID:15897609
(PMID:15897609), (PMID:16478722), (PMID:8876250)
(MGI:6467714|PMID:15897609)		 RGD PMID:8876250 PMID:15897609 PMID:16478722 PMID:15897609 MGI:6467714, RGD:39458034 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 enables ISO (PMID:18772377), (PMID:25339683), (PMID:27238017) RGD PMID:18772377 PMID:25339683 PMID:27238017 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155 		JBrowse link
G Osbpl2 oxysterol binding protein-like 2 enables ISO (PMID:30581148) RGD PMID:30581148 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219 		JBrowse link
G Pltp phospholipid transfer protein enables ISO (MGI:1332889|PMID:10079112) RGD PMID:10079112 MGI:1332889 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Scp2 sterol carrier protein 2 enables IDA
ISO		 PMID:8063752
(PMID:7642518)		 RGD PMID:7642518 PMID:8063752 PMID:8063752 RGD:9850162, RGD:9850162 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Star steroidogenic acute regulatory protein TAS RGD PMID:11861536 RGD:634518 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stard3 StAR-related lipid transfer domain containing 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:83,357,329...83,379,873
Ensembl chr10:83,357,359...83,550,976 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 enables ISO
IBA		 (PMID:18403318)
GO_REF:0000033		 RGD
GO_Central		 PMID:18403318 GO_REF:0000033 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024 		JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 enables ISO
IBA		 (PMID:18403318)
GO_REF:0000033		 RGD
GO_Central		 PMID:18403318 GO_REF:0000033 NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 20488
    transporter activity 1237
      lipid transporter activity 171
        lipid transfer activity 52
          sterol transfer activity 23
            cholesterol transfer activity 22
paths to the root