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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cell proliferation involved in heart morphogenesis
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Accession:GO:2000136 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.


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regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:3721185 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
negative regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx3 T-box transcription factor 3 involved_in ISO (PMID:22130515) RGD PMID:22130515 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 acts_upstream_of_or_within ISO (PMID:19620969) RGD PMID:19620969 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
positive regulation of cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:21474815) RGD PMID:21474815 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
positive regulation of cell proliferation involved in heart morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P31266 (MGI:3701380|PMID:17336907)		 Ensembl
RGD		 PMID:17336907 GO_REF:0000107 MGI:3701380 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Naca nascent polypeptide associated complex subunit alpha involved_in ISO (MGI:4867362|PMID:21071677) RGD PMID:21071677 MGI:4867362 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:3701380 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385468|MGI:2450311 (PMID:17350610) RGD PMID:17350610 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
positive regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of_or_within ISO MGI:102780 (PMID:21364285) RGD PMID:21364285 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Gng5 G protein subunit gamma 5 acts_upstream_of_or_within ISO (PMID:24599258) RGD PMID:24599258 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513 		JBrowse link
G Six1 SIX homeobox 1 acts_upstream_of_or_within ISO MGI:109344 (PMID:21364285) RGD PMID:21364285 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Tbx1 T-box transcription factor 1 acts_upstream_of_or_within ISO (PMID:19745164) RGD PMID:19745164 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2387851 (PMID:22898775)		 Ensembl
RGD		 PMID:22898775 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
regulation of cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 IMP RGD PMID:18824567 RGD:2325311 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19620969)		 Ensembl
RGD		 PMID:19620969 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4413411|PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19609448)		 Ensembl
RGD		 PMID:19609448 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447758 (PMID:19620969)		 Ensembl
RGD		 PMID:19620969 GO_REF:0000107 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4821832 (PMID:27340223)		 Ensembl
RGD		 PMID:27340223 GO_REF:0000107 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cell population proliferation 2296
        regulation of cell population proliferation 1924
          regulation of cell proliferation involved in heart morphogenesis 20
            negative regulation of cell proliferation involved in heart morphogenesis + 3
            positive regulation of cell proliferation involved in heart morphogenesis + 6
            regulation of cardioblast proliferation + 12
            regulation of cell proliferation involved in heart valve morphogenesis + 3
            regulation of cell proliferation involved in outflow tract morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            circulatory system development 1367
              heart development 742
                heart morphogenesis 294
                  cell proliferation involved in heart morphogenesis 22
                    regulation of cell proliferation involved in heart morphogenesis 20
                      negative regulation of cell proliferation involved in heart morphogenesis + 3
                      positive regulation of cell proliferation involved in heart morphogenesis + 6
                      regulation of cardioblast proliferation + 12
                      regulation of cell proliferation involved in heart valve morphogenesis + 3
                      regulation of cell proliferation involved in outflow tract morphogenesis + 0
paths to the root