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ONTOLOGY REPORT - ANNOTATIONS

Term:pericardium development
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Accession:GO:0060039 term browser browse the term
Definition:The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.


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pericardium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583785 (PMID:16314491)		 Ensembl
RGD		 PMID:16314491 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Ccm2 CCM2 scaffold protein acts_upstream_of_or_within ISO MGI:1924696|MGI:3512761 (PMID:19151727) RGD PMID:19151727 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 acts_upstream_of_or_within ISO MGI:2384924|MGI:3838392 (PMID:19151727) RGD PMID:19151727 NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051 		JBrowse link
G Mecom MDS1 and EVI1 complex locus acts_upstream_of_or_within ISO MGI:2158381 (PMID:17029558) RGD PMID:17029558 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Nkx2-6 NK2 homeobox 6 involved_in ISO (MGI:3828420|PMID:9545560) RGD PMID:9545560 MGI:3828420 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247 		JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (PMID:17553904) RGD PMID:17553904 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:4437211 (PMID:20133625) RGD PMID:20133625 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Smad2 SMAD family member 2 acts_upstream_of_or_within ISO MGI:1201674 (PMID:15183723) RGD PMID:15183723 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO MGI:108051 (PMID:15183723) RGD PMID:15183723 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO
IEA
ISS		 (PMID:15138308)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15138308 GO_REF:0000024 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (PMID:19056682) RGD PMID:19056682 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp5 bone morphogenetic protein 5 involved_in ISO UniProtKB:P23359 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO UniProtKB:P49003 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO
IEA		 (MGI:3056036|PMID:15466159)
GO_REF:0000107		 RGD
Ensembl		 PMID:15466159 GO_REF:0000107 MGI:3056036 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of
acts_upstream_of_or_within		 ISO MGI:98958 (PMID:19056682)
MGI:98958 (PMID:19795512)		 RGD PMID:19056682 PMID:19795512 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881), (MGI:4837019|PMID:20890042), (MGI:5298073|PMID:21311046) RGD PMID:14701881 PMID:20890042 PMID:21311046 MGI:3027664 MGI:4837019 MGI:5298073 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:2155441 (PMID:9030684) RGD PMID:9030684 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3579960|PMID:15901664) RGD PMID:15901664 MGI:3579960 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1298218 (PMID:19795512) RGD PMID:19795512 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857617 (PMID:19056682)		 Ensembl
RGD		 PMID:19056682 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
proepicardium cell migration involved in pericardium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flrt3 fibronectin leucine rich transmembrane protein 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3796818|PMID:18448090)		 UniProt
RGD		 PMID:18448090 GO_REF:0000024 MGI:3796818 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841 		JBrowse link
visceral serous pericardium development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3715149|MGI:3801682 (PMID:21350214)		 Ensembl
RGD		 PMID:21350214 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Wt1 WT1 transcription factor involved_in ISO
ISS
IEA		 UniProtKB:P22561 (PMID:10101119)
GO_REF:0000024
(MGI:1333093|PMID:10101119)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10101119 GO_REF:0000024 GO_REF:0000107 MGI:1333093 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        animal organ development 3650
          heart development 740
            pericardium development 21
              pericardium morphogenesis + 9
              visceral serous pericardium development 2
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            circulatory system development 1367
              heart development 740
                pericardium development 21
                  pericardium morphogenesis + 9
                  visceral serous pericardium development 2
paths to the root