Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear replisome
go back to main search page
Accession:GO:0043601 term browser browse the term
Definition:A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.


show annotations for term's descendants           Sort by:
alpha DNA polymerase:primase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit part_of
located_in		 IDA
ISO
IBA
IEA
ISS
IC		 (MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492), (PMID:9584195)
GO_REF:0000033
GO_REF:0000114
(PMID:26975377)
(PMID:2175912), (PMID:22465957), (PMID:26975377), (PMID:8026492)
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
ComplexPortal
Ensembl
UniProt		 PMID:2175912 PMID:8026492 PMID:9584195 PMID:10523676 PMID:22465957 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 MGI:3687659 MGI:6478526, RGD:1580605, RGD:2307013 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit part_of
located_in		 TAS
ISO
IBA
IEA
ISS
IC		 (MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492), (PMID:9584195)
GO_REF:0000033
GO_REF:0000114
GO_REF:0000107
(PMID:26975377)
GO_REF:0000024
(PMID:22465957), (PMID:26975377), (PMID:8026492)		 RGD
GO_Central
ComplexPortal
Ensembl
UniProt		 PMID:8026492 PMID:9584195 PMID:10523676 PMID:22465957 PMID:26975377 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 MGI:3687659 MGI:6478526, RGD:633584, RGD:2307013 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348 		JBrowse link
G Prim1 DNA primase subunit 1 part_of
located_in		 ISO (PMID:26975377), (PMID:8026492)
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492)		 RGD PMID:8026492 PMID:10523676 PMID:26975377 MGI:3687659 MGI:6478526 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prim2 DNA primase subunit 2 part_of
located_in		 ISO
IBA
IEA
ISS		 (PMID:26975377), (PMID:8026492)
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492)
GO_REF:0000033
GO_REF:0000114
GO_REF:0000117
GO_REF:0000024		 RGD
GO_Central
ComplexPortal
UniProt		 PMID:8026492 PMID:10523676 PMID:26975377 GO_REF:0000024 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:3687659 MGI:6478526 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030 		JBrowse link
delta DNA polymerase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 DNA polymerase delta 1, catalytic subunit part_of
located_in		 IC
IDA
ISO
IEA
IBA		 (PMID:11595739), (PMID:22465957)
(MGI:6383350|PMID:11595739)
(PMID:12403614)
GO_REF:0000114
GO_REF:0000117
GO_REF:0000033		 RGD
ComplexPortal
UniProt
GO_Central		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:6383350, RGD:2307013, RGD:729526 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit part_of
located_in		 IC
IDA
ISO
IEA
IBA		 (PMID:11595739), (PMID:22465957)
(MGI:6383350|PMID:11595739)
(PMID:12403614)
GO_REF:0000117
GO_REF:0000114
GO_REF:0000033		 RGD
UniProt
ComplexPortal
GO_Central		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:6383350, RGD:2307013, RGD:729526 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit part_of
located_in		 IC
ISO
IBA		 (PMID:11595739), (PMID:22465957)
(MGI:6383350|PMID:11595739)
(PMID:12403614)
GO_REF:0000114
GO_REF:0000033		 RGD
ComplexPortal
GO_Central		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 GO_REF:0000033 GO_REF:0000114 MGI:6383350, RGD:2307013 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit located_in
part_of		 IC
ISO
IBA		 (PMID:12403614)
GO_REF:0000114
GO_REF:0000033		 RGD
ComplexPortal
GO_Central		 PMID:12403614 PMID:7503737 GO_REF:0000033 GO_REF:0000114, RGD:2307013 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcas2 BCAS2, pre-mRNA processing factor located_in ISO (PMID:24332808) RGD PMID:24332808 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Cdc5l cell division cycle 5-like part_of
located_in		 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:24332808)		 Ensembl
UniProt
RGD		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease located_in ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Helb DNA helicase B located_in ISO (PMID:26774285) RGD PMID:26774285 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Plrg1 pleiotropic regulator 1 part_of
located_in		 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:24332808)		 Ensembl
UniProt
RGD		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of
located_in		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:24332808)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Rpa1 replication protein A1 part_of
located_in		 IDA
IBA
ISO		 GO_REF:0000033
(PMID:11927569), (PMID:27723717), (PMID:27723720)
(PMID:11927569), (PMID:7760808)		 GO_Central
RGD		 PMID:7760808 PMID:11927569 PMID:27723717 PMID:27723720 PMID:8463251 More... GO_REF:0000033, RGD:2307012, RGD:2307013 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 located_in
part_of		 IDA
ISO
IBA		 (PMID:11927569)
(PMID:11927569), (PMID:2406247), (PMID:27723717), (PMID:27723720)
GO_REF:0000033		 RGD
GO_Central		 PMID:2406247 PMID:11927569 PMID:27723717 PMID:27723720 PMID:8463251 More... GO_REF:0000033, RGD:2307012, RGD:2307013 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 part_of
located_in		 IDA
IBA
ISO		 GO_REF:0000033
(PMID:11927569), (PMID:7760808)		 GO_Central
RGD		 PMID:7760808 PMID:11927569 PMID:7503737 GO_REF:0000033, RGD:2307013 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpa3l1 replication protein A3 like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 located_in ISS
ISO		 GO_REF:0000024
(PMID:19793862), (PMID:19793863)		 UniProt
RGD		 PMID:19793862 PMID:19793863 GO_REF:0000024 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein located_in ISS
ISO		 GO_REF:0000024
(PMID:21055983)		 UniProt
RGD		 PMID:21055983 GO_REF:0000024 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor located_in ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6602
      nuclear protein-containing complex 1276
        nuclear replisome 21
          DNA replication factor A complex 13
          alpha DNA polymerase:primase complex 4
          delta DNA polymerase complex 4
          nuclear DNA replication factor C complex + 0
Path 2
Term Annotations click to browse term
  cellular_component 20624
    cellular anatomical entity 20386
      organelle 13799
        membrane-bounded organelle 12396
          intracellular membrane-bounded organelle 11845
            nucleus 7395
              nuclear lumen 4027
                nuclear chromosome 226
                  nuclear replication fork 37
                    nuclear replisome 21
                      DNA replication factor A complex 13
                      alpha DNA polymerase:primase complex 4
                      delta DNA polymerase complex 4
                      nuclear DNA replication factor C complex + 0
paths to the root