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Ontology Browser

nuclear DNA replication factor C complex (GO:0043599)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
alpha DNA polymerase:primase complex  
cytoplasmic DNA replication factor C complex 
delta DNA polymerase complex  
DNA replication factor A complex  
nuclear DNA replication factor C complex +  
A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.

Exact Synonyms: nuclear RFC
Definition Sources: GOC:mtg_sensu, PMID:14614842

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.