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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear replication fork
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Accession:GO:0043596 term browser browse the term
Definition:The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.


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nuclear replication fork term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1b bromodomain adjacent to zinc finger domain, 1B located_in ISO (PMID:15543136) RGD PMID:15543136 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 is_active_in ISS
ISO		 GO_REF:0000024
(PMID:33412112)		 UniProt
RGD		 PMID:33412112 GO_REF:0000024 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase located_in
is_active_in		 ISO
IBA		 (PMID:27723717), (PMID:27723720)
GO_REF:0000033		 RGD
GO_Central		 PMID:27723717 PMID:27723720 GO_REF:0000033 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104 		JBrowse link
G LOC134486336 ewing's tumor-associated antigen 1 homolog is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Mcm10 minichromosome maintenance 10 replication initiation factor is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mms22l MMS22-like, DNA repair protein located_in
is_active_in		 ISO
IBA		 (PMID:21055983), (PMID:21055984)
GO_REF:0000033
(PMID:27797818)		 RGD
GO_Central		 PMID:21055983 PMID:21055984 PMID:27797818 GO_REF:0000033 NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 is_active_in ISO
ISS		 (PMID:33412112)
GO_REF:0000024		 RGD
UniProt		 PMID:33412112 GO_REF:0000024 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen located_in ISO (PMID:15543136), (PMID:21383955) RGD PMID:15543136 PMID:21383955 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 located_in ISO (PMID:15543136) RGD PMID:15543136 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` located_in ISO (PMID:21549307) RGD PMID:21549307 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563 		JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein located_in
is_active_in		 ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:26527279), (PMID:29478807)
(PMID:21055983), (PMID:21055984)		 UniProt
GO_Central
RGD		 PMID:21055983 PMID:21055984 PMID:26527279 PMID:29478807 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Trex1 three prime repair exonuclease 1 located_in ISO (PMID:18045533) RGD PMID:18045533 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096 		JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 located_in ISO (PMID:16051670) RGD PMID:16051670 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936 		JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 located_in
is_active_in		 ISO
IBA		 (PMID:22704558), (PMID:22705370), (PMID:22759634)
GO_REF:0000033		 RGD
GO_Central		 PMID:22704558 PMID:22705370 PMID:22759634 GO_REF:0000033 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670 		JBrowse link
alpha DNA polymerase:primase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit part_of IDA
ISO
IBA
IEA
ISS
IC		 (PMID:10523676), (PMID:8026492), (PMID:9584195)
GO_REF:0000114
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492), (PMID:9584195)
GO_REF:0000033
(PMID:2175912), (PMID:22465957), (PMID:26975377), (PMID:8026492)
GO_REF:0000107
GO_REF:0000024		 RGD
ComplexPortal
GO_Central
Ensembl
UniProt		 PMID:2175912 PMID:8026492 PMID:9584195 PMID:10523676 PMID:22465957 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 MGI:3687659 MGI:6478526, RGD:1580605, RGD:2307013 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit part_of TAS
ISO
IBA
IEA
ISS
IC		 (PMID:10523676), (PMID:8026492), (PMID:9584195)
GO_REF:0000114
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492), (PMID:9584195)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
(PMID:22465957), (PMID:26975377), (PMID:8026492)		 RGD
ComplexPortal
GO_Central
Ensembl
UniProt		 PMID:8026492 PMID:9584195 PMID:10523676 PMID:22465957 PMID:26975377 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 MGI:3687659 MGI:6478526, RGD:633584, RGD:2307013 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348 		JBrowse link
G Prim1 DNA primase subunit 1 part_of ISO (PMID:26975377), (PMID:8026492)
(PMID:10523676), (PMID:8026492)
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492)		 RGD PMID:8026492 PMID:10523676 PMID:26975377 MGI:3687659 MGI:6478526 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prim2 DNA primase subunit 2 part_of ISO
IBA
IEA
ISS		 (PMID:26975377), (PMID:8026492)
(PMID:10523676), (PMID:8026492)
GO_REF:0000114
(MGI:3687659|PMID:10523676), (MGI:6478526|PMID:8026492)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000024		 RGD
ComplexPortal
GO_Central
UniProt		 PMID:8026492 PMID:10523676 PMID:26975377 GO_REF:0000024 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:3687659 MGI:6478526 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030 		JBrowse link
delta DNA polymerase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 DNA polymerase delta 1, catalytic subunit part_of IC
IDA
ISO
IEA
IBA		 (MGI:6383350|PMID:11595739)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000114
(PMID:11595739), (PMID:12403614), (PMID:22465957)		 RGD
UniProt
GO_Central
ComplexPortal		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:6383350, RGD:2307013, RGD:729526 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit part_of IC
IDA
ISO
IEA
IBA		 (MGI:6383350|PMID:11595739)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000114
(PMID:11595739), (PMID:12403614), (PMID:22465957)		 RGD
UniProt
GO_Central
ComplexPortal		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 PMID:10541966 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117 MGI:6383350, RGD:2307013, RGD:729526 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit part_of IC
ISO
IBA		 (MGI:6383350|PMID:11595739)
GO_REF:0000033
GO_REF:0000114
(PMID:11595739), (PMID:12403614), (PMID:22465957)		 RGD
GO_Central
ComplexPortal		 PMID:11595739 PMID:12403614 PMID:22465957 PMID:7503737 GO_REF:0000033 GO_REF:0000114 MGI:6383350, RGD:2307013 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit part_of IC
IBA
ISO		 GO_REF:0000033
GO_REF:0000114
(PMID:12403614)		 GO_Central
ComplexPortal
RGD		 PMID:12403614 PMID:7503737 GO_REF:0000033 GO_REF:0000114, RGD:2307013 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcas2 BCAS2, pre-mRNA processing factor located_in ISO (PMID:24332808) RGD PMID:24332808 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389 		JBrowse link
G Cdc5l cell division cycle 5-like part_of
located_in		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:24332808)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease located_in ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Helb DNA helicase B located_in ISO (PMID:26774285) RGD PMID:26774285 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Plrg1 pleiotropic regulator 1 part_of
located_in		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:24332808)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 part_of
located_in		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:24332808)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Rpa1 replication protein A1 part_of IDA
ISO
IBA		 (PMID:11927569), (PMID:27723717), (PMID:27723720), (PMID:7760808)
GO_REF:0000033		 RGD
GO_Central		 PMID:7760808 PMID:11927569 PMID:27723717 PMID:27723720 PMID:8463251 More... GO_REF:0000033, RGD:2307012, RGD:2307013 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa2 replication protein A2 part_of IDA
IBA
ISO		 GO_REF:0000033
(PMID:11927569), (PMID:2406247), (PMID:27723717), (PMID:27723720)		 GO_Central
RGD		 PMID:2406247 PMID:11927569 PMID:27723717 PMID:27723720 PMID:8463251 More... GO_REF:0000033, RGD:2307012, RGD:2307013 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rpa3 replication protein A3 part_of IDA
ISO
IBA		 (PMID:11927569), (PMID:7760808)
GO_REF:0000033		 RGD
GO_Central		 PMID:7760808 PMID:11927569 PMID:7503737 GO_REF:0000033, RGD:2307013 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpa3l1 replication protein A3 like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048 		JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 located_in ISS
ISO		 GO_REF:0000024
(PMID:19793862), (PMID:19793863)		 UniProt
RGD		 PMID:19793862 PMID:19793863 GO_REF:0000024 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein located_in ISS
ISO		 GO_REF:0000024
(PMID:21055983)		 UniProt
RGD		 PMID:21055983 GO_REF:0000024 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor located_in ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
replication fork protection complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC120094818 TIMELESS-interacting protein-like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Timeless timeless circadian regulator part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tipin timeless interacting protein part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      replication fork 76
        nuclear replication fork 39
          nuclear replisome + 21
          replication fork protection complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20814
    cellular anatomical structure 20574
      organelle 14007
        intracellular organelle 13599
          intracellular membrane-bounded organelle 12057
            nucleus 7485
              nuclear lumen 4086
                nuclear chromosome 227
                  nuclear replication fork 39
                    nuclear replisome + 21
                    replication fork protection complex 4
paths to the root