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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear replication fork
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Accession:GO:0043596 term browser browse the term
Definition:The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.


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nuclear replication fork term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1b bromodomain adjacent to zinc finger domain, 1B colocalizes_with ISO (PMID:15543136) RGD PMID:15543136 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase ISO
IBA
(PMID:27723717), (PMID:27723720)
PMID:21873635
RGD PMID:27723717, PMID:27723720, PMID:21873635 RGD:13792537 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677
JBrowse link
G Mms22l MMS22-like, DNA repair protein ISO
IBA
(PMID:21055983), (PMID:21055984)
PMID:21873635
RGD PMID:21055983, PMID:21055984, PMID:21873635 RGD:13792537 NCBI chr 5:38,844,502...38,960,989
Ensembl chr 5:38,844,488...38,961,035
JBrowse link
G Pcna proliferating cell nuclear antigen ISO (PMID:15543136), (PMID:21383955) RGD PMID:15543136, PMID:21383955 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 colocalizes_with ISO (PMID:15543136) RGD PMID:15543136 NCBI chr19:30,936,703...30,969,454
Ensembl chr19:30,936,703...30,969,454
JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` ISO (PMID:21549307) RGD PMID:21549307 NCBI chr 4:95,884,020...95,945,248
Ensembl chr 4:95,884,743...95,945,248
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:79,943,775...79,990,230
Ensembl chr 9:79,944,132...79,990,229
JBrowse link
G Tonsl tonsoku-like, DNA repair protein ISS
ISO
GO_REF:0000024
(PMID:21055983), (PMID:21055984)
UniProt
RGD
PMID:21055983, PMID:21055984 GO_REF:0000024 NCBI chr 7:117,688,397...117,703,139
Ensembl chr 7:117,688,397...117,703,094
JBrowse link
G Trex1 three prime repair exonuclease 1 ISO (MGI:MGI:3818783|PMID:18045533) RGD PMID:18045533 MGI:MGI:3818783 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427
JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:24,021,674...24,056,073
Ensembl chr15:24,021,674...24,056,073
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 ISO (PMID:16051670) RGD PMID:16051670 NCBI chr14:86,645,875...86,662,419
Ensembl chr14:86,652,365...86,661,441
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 ISO
IBA
(PMID:22704558), (PMID:22705370), (PMID:22759634)
PMID:21873635
RGD PMID:22704558, PMID:22705370, PMID:22759634, PMID:21873635 RGD:13792537 NCBI chr13:44,661,375...44,812,430
Ensembl chr13:44,661,398...44,798,543
JBrowse link
alpha DNA polymerase:primase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit IDA
ISO
IBA
ISS
IEA
IC
(PMID:2175912), (PMID:22465957)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:1203906|PMID:9584195)
RGD
UniProt
Ensembl
PMID:2175912, PMID:9584195, PMID:22465957, PMID:7670930, PMID:21873635, PMID:7503737 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1203906, RGD:1580605, RGD:13792537, RGD:2307013 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit TAS
ISO
IBA
IEA
IC
(PMID:22465957)
PMID:21873635
GO_REF:0000107
(MGI:MGI:1203906|PMID:9584195)
RGD
Ensembl
PMID:9584195, PMID:22465957, PMID:11536367, PMID:21873635, PMID:7503737 GO_REF:0000107, MGI:MGI:1203906, RGD:633584, RGD:13792537, RGD:2307013 NCBI chr 1:221,297,417...221,321,601
Ensembl chr 1:221,273,538...221,321,570
JBrowse link
G Prim1 DNA primase subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,435,524...2,451,169
Ensembl chr 7:2,435,553...2,451,165
JBrowse link
G Prim2 DNA primase subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:38,535,435...38,745,058
Ensembl chr 9:38,536,920...38,745,099
JBrowse link
delta DNA polymerase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 DNA polymerase delta 1, catalytic subunit IC
ISO
IEA
IBA
IDA
(MGI:MGI:6383350|PMID:11595739)
GO_REF:0000107
(PMID:11595739), (PMID:22465957)
PMID:21873635
RGD
Ensembl
PMID:11595739, PMID:22465957, PMID:7503737, PMID:21873635, PMID:10541966 GO_REF:0000107, MGI:MGI:6383350, RGD:2307013, RGD:13792537, RGD:729526 NCBI chr 1:100,538,066...100,554,105
Ensembl chr 1:100,537,900...100,554,488
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit IC
ISO
IBA
IDA
(MGI:MGI:6383350|PMID:11595739)
(PMID:11595739), (PMID:22465957)
PMID:21873635
RGD PMID:11595739, PMID:22465957, PMID:7503737, PMID:21873635, PMID:10541966 MGI:MGI:6383350, RGD:2307013, RGD:13792537, RGD:729526 NCBI chr14:86,111,416...86,117,578
Ensembl chr14:86,111,294...86,117,578
JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit IC
IBA
ISO
PMID:21873635
(PMID:11595739), (PMID:22465957)
(MGI:MGI:6383350|PMID:11595739)
RGD PMID:11595739, PMID:22465957, PMID:7503737, PMID:21873635 MGI:MGI:6383350, RGD:2307013, RGD:13792537 NCBI chr 1:165,085,142...165,122,385
Ensembl chr 1:165,083,622...165,123,455
JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit IC
IBA
PMID:21873635 RGD
GO_Central
PMID:7503737, PMID:21873635 RGD:2307013, RGD:13792537 NCBI chr 1:219,480,841...219,483,244
Ensembl chr 1:219,481,575...219,483,241
JBrowse link
DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC095390.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr12:51,965,417...51,965,779 JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor colocalizes_with ISO (PMID:24332808) RGD PMID:24332808 NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
JBrowse link
G Cdc5l cell division cycle 5-like colocalizes_with ISO
ISS
(PMID:24332808)
GO_REF:0000024
RGD
UniProt
PMID:24332808 GO_REF:0000024 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease colocalizes_with ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Helb DNA helicase B colocalizes_with ISO (PMID:26774285) RGD PMID:26774285 NCBI chr 7:64,860,641...64,888,146
Ensembl chr 7:64,860,666...64,887,448
JBrowse link
G LOC100362927 replication protein A3-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:51,965,390...51,965,816 JBrowse link
G Plrg1 pleiotropic regulator 1 colocalizes_with ISO
IBA
ISS
(PMID:24332808)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:24332808, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:182,040,338...182,056,669
Ensembl chr 2:182,040,318...182,056,673
JBrowse link
G Prpf19 pre-mRNA processing factor 19 colocalizes_with ISO
ISS
(PMID:24332808)
GO_REF:0000024
RGD
UniProt
PMID:24332808 GO_REF:0000024 NCBI chr 1:226,947,065...226,958,147
Ensembl chr 1:226,947,105...226,958,144
JBrowse link
G Rpa1 replication protein A1 IDA
IBA
ISO
PMID:21873635
UniProtKB:P15927 (PMID:11927569), (PMID:16135809), (PMID:27723717), (PMID:27723720)
RGD PMID:11927569, PMID:16135809, PMID:27723717, PMID:27723720, PMID:8463251, PMID:21873635, PMID:7503737 RGD:2307012, RGD:13792537, RGD:2307013 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rpa2 replication protein A2 IDA
IBA
ISO
PMID:21873635
UniProtKB:P27694 (PMID:11927569), (PMID:16135809), (PMID:2406247), (PMID:27723717), (PMID:27723720)
RGD PMID:2406247, PMID:11927569, PMID:16135809, PMID:27723717, PMID:27723720, PMID:8463251, PMID:21873635, PMID:7503737 RGD:2307012, RGD:13792537, RGD:2307013 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
JBrowse link
G Rpa3 replication protein A3 IDA
IBA
ISO
PMID:21873635
(PMID:11927569)
RGD PMID:11927569, PMID:7503737, PMID:21873635 RGD:2307013, RGD:13792537 NCBI chr 4:34,279,320...34,282,351
Ensembl chr 4:34,279,320...34,282,351
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 colocalizes_with ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:19793862), (PMID:19793863)
UniProt
RGD
PMID:19793862, PMID:19793863, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 9:79,943,775...79,990,230
Ensembl chr 9:79,944,132...79,990,229
JBrowse link
G Tonsl tonsoku-like, DNA repair protein colocalizes_with ISO
ISS
(PMID:21055983)
GO_REF:0000024
RGD
UniProt
PMID:21055983 GO_REF:0000024 NCBI chr 7:117,688,397...117,703,139
Ensembl chr 7:117,688,397...117,703,094
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor colocalizes_with ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
replication fork protection complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc45 cell division cycle 45 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Gins2 GINS complex subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
JBrowse link
G Gins4 GINS complex subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:73,584,412...73,596,808
Ensembl chr16:73,584,521...73,596,793
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Timeless timeless circadian regulator IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Tipin timeless interacting protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:173,761...174,959
Ensembl chr 5:173,744...174,921
JBrowse link
G Top1 DNA topoisomerase I IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:24,021,674...24,056,073
Ensembl chr15:24,021,674...24,056,073
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      replication fork 73
        nuclear replication fork 40
          nuclear replisome + 22
          replication fork protection complex 9
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      organelle 13271
        intracellular organelle 12917
          intracellular membrane-bounded organelle 10505
            nucleus 6974
              nuclear lumen 3869
                nuclear chromosome 248
                  nuclear replication fork 40
                    nuclear replisome + 22
                    replication fork protection complex 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.