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Gene: Ercc5 (ERCC excision repair 5, endonuclease) Rattus norvegicus
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Symbol: Ercc5
Name: ERCC excision repair 5, endonuclease
Description: Predicted to have several functions, including DNA binding activity; RNA polymerase II complex binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including DNA metabolic process; growth; and response to UV. Predicted to colocalize with the DNA replication factor A complex. Human ortholog(s) of this gene implicated in melanoma and xeroderma pigmentosum group G. Orthologous to human ERCC5 (ERCC excision repair 5, endonuclease); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA repair protein complementing XP-G cells; Ercc5_mapped; excision repair cross-complementation group 5; excision repair cross-complementing rodent repair deficiency, complementation group 5; excision repair cross-complementing rodent repair deficiency, complementation group 5 (mapped); Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum complementation group G (Cockayne syndrome)); excision repair cross-complementing rodent repair deficiency,complementation group 5; Xpg
Orthologs:
Homo sapiens (human) : ERCC5 (ERCC excision repair 5, endonuclease)  HGNC  Alliance
Mus musculus (house mouse) : Ercc5 (excision repair cross-complementing rodent repair deficiency, complementation group 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ercc5 (ERCC excision repair 5, endonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : ERCC5 (ERCC excision repair 5, endonuclease)
Canis lupus familiaris (dog) : ERCC5 (ERCC excision repair 5, endonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101968680 (DNA repair protein complementing XP-G cells)
Sus scrofa (pig) : ERCC5 (ERCC excision repair 5, endonuclease)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0950,928,847 - 50,970,962 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0950,591,955 - 50,637,694 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4943,248,023 - 43,293,196 (+)NCBIRGSC3.4rn4RGSC3.4
Celera944,012,579 - 44,057,619 (+)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ercc5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1586176
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.