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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA replication factor A complex
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Accession:GO:0005662 term browser browse the term
Definition:A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.
Synonyms:exact_synonym: RPA;   replication protein A
 xref: Wikipedia:Replication_protein_A



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DNA replication factor A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC095390.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Bcas2 BCAS2, pre-mRNA processing factor colocalizes_with
part_of
ISO
IEA
(PMID:24332808)
GO_REF:0000107
RGD
Ensembl
PMID:24332808 GO_REF:0000107 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
JBrowse link
G Cdc5l cell division cycle 5-like colocalizes_with ISO
ISS
(PMID:24332808)
GO_REF:0000024
RGD
UniProt
PMID:24332808 GO_REF:0000024 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease colocalizes_with ISO (PMID:7700386) RGD PMID:7700386 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Helb DNA helicase B colocalizes_with
part_of
ISO
IEA
(PMID:26774285)
GO_REF:0000107
RGD
Ensembl
PMID:26774285 GO_REF:0000107 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G LOC100362927 replication protein A3-like part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:45,908,653...45,909,063
Ensembl chr12:45,908,683...45,909,048
JBrowse link
G Plrg1 pleiotropic regulator 1 colocalizes_with ISO
ISS
(PMID:24332808)
GO_REF:0000024
RGD
UniProt
PMID:24332808 GO_REF:0000024 NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522
JBrowse link
G Prpf19 pre-mRNA processing factor 19 colocalizes_with ISO
ISS
(PMID:24332808)
GO_REF:0000024
RGD
UniProt
PMID:24332808 GO_REF:0000024 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Rpa1 replication protein A1 located_in
part_of
IDA
ISO
IBA
(PMID:11927569), (PMID:7760808)
UniProtKB:P15927 (PMID:11927569), (PMID:16135809), (PMID:27723717), (PMID:27723720)
PMID:21873635
RGD PMID:7760808 PMID:11927569 PMID:16135809 PMID:27723717 PMID:27723720 More... RGD:2307012, RGD:13792537, RGD:2307013 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rpa2 replication protein A2 located_in
part_of
IDA
ISO
IBA
(PMID:11927569)
UniProtKB:P27694 (PMID:11927569), (PMID:16135809), (PMID:2406247), (PMID:27723717), (PMID:27723720)
PMID:21873635
RGD PMID:2406247 PMID:11927569 PMID:16135809 PMID:27723717 PMID:27723720 More... RGD:2307012, RGD:13792537, RGD:2307013 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350
JBrowse link
G Rpa3 replication protein A3 located_in
part_of
IDA
ISO
IBA
(PMID:11927569), (PMID:7760808)
PMID:21873635
RGD PMID:7760808 PMID:11927569 PMID:7503737 PMID:21873635 RGD:2307013, RGD:13792537 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 colocalizes_with ISS
ISO
GO_REF:0000024
(PMID:19793862), (PMID:19793863)
UniProt
RGD
PMID:19793862 PMID:19793863 GO_REF:0000024 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Tonsl tonsoku-like, DNA repair protein colocalizes_with ISO
ISS
(PMID:21055983)
GO_REF:0000024
RGD
UniProt
PMID:21055983 GO_REF:0000024 NCBI chr 7:108,345,704...108,360,792
Ensembl chr 7:108,346,047...108,360,750
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor colocalizes_with
part_of
ISO
IEA
(PMID:7700386)
GO_REF:0000107
RGD
Ensembl
PMID:7700386 GO_REF:0000107 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    protein-containing complex 6165
      nuclear protein-containing complex 1289
        DNA replication factor A complex 14
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      organelle 13088
        membrane-bounded organelle 11697
          intracellular membrane-bounded organelle 11218
            nucleus 7051
              nuclear lumen 3941
                nuclear chromosome 245
                  nuclear replication fork 37
                    nuclear replisome 23
                      DNA replication factor A complex 14
paths to the root