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ONTOLOGY REPORT - ANNOTATIONS


Term:spinal cord dorsal/ventral patterning
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Accession:GO:0021513 term browser browse the term
Definition:The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms:exact_synonym: spinal cord dorsoventral patterning



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spinal cord dorsal/ventral patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrd chordin involved_in ISO
IEA
(PMID:11472837)
GO_REF:0000107
RGD
Ensembl
PMID:11472837 GO_REF:0000107 NCBI chr11:93,676,400...93,685,584
Ensembl chr11:80,171,994...80,180,673
JBrowse link
G Fuz fuzzy planar cell polarity protein acts_upstream_of_or_within ISO MGI:4346364 (PMID:21761479) RGD PMID:21761479 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509|MGI:2158472|MGI:95729|MGI:99833 (PMID:11748151), (PMID:15215207), (PMID:16364285) RGD PMID:11748151 PMID:15215207 PMID:16364285 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728|MGI:99833 (PMID:15215207), (PMID:16364285) RGD PMID:15215207 PMID:16364285 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (PMID:21209331) RGD PMID:21209331 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458
JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:1859153 (PMID:21761479) RGD PMID:21761479 NCBI chr15:35,685,678...35,786,875
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (PMID:21761479)
Ensembl
RGD
PMID:21761479 GO_REF:0000107 NCBI chr 2:125,528,965...125,613,295
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2137533|MGI:2682064|MGI:95728|MGI:95729 (PMID:14603322), (PMID:15755804), (PMID:16364285) RGD PMID:14603322 PMID:15755804 PMID:16364285 NCBI chr 9:43,440,047...43,463,327
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
IDA
GO_REF:0000107
MGI:1857796 (PMID:11748151)
PMID:9230312
Ensembl
RGD
PMID:11748151 PMID:9230312 GO_REF:0000107, RGD:8553789 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Smo smoothened, frizzled class receptor involved_in IEA
ISO
GO_REF:0000107
(PMID:21209331)
Ensembl
RGD
PMID:21209331 GO_REF:0000107 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:3619046 (PMID:16459298) RGD PMID:16459298 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (PMID:15215207) RGD PMID:15215207 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:15215207) RGD PMID:15215207 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (PMID:15215207) RGD PMID:15215207 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:15215207) RGD PMID:15215207 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:16020526)
UniProt
RGD
PMID:16020526 GO_REF:0000024 NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO
IEA
UniProtKB:Q8K3Q3 (PMID:17728344)
GO_REF:0000107
RGD
Ensembl
PMID:17728344 GO_REF:0000107 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Foxn4 forkhead box N4 involved_in ISO (PMID:16020526), (PMID:17728344) RGD PMID:16020526 PMID:17728344 NCBI chr12:47,997,308...48,020,526
Ensembl chr12:42,340,323...42,359,921
JBrowse link
ventral spinal cord interneuron fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1932100 (PMID:10217145) RGD PMID:10217145 NCBI chr 3:155,072,621...155,083,699
Ensembl chr 3:134,620,039...134,622,411
JBrowse link
ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbx1 developing brain homeobox 1 acts_upstream_of_or_within ISO MGI:2182329 (PMID:11239429) RGD PMID:11239429 NCBI chr 1:108,484,846...108,490,381
Ensembl chr 1:99,349,608...99,354,038
JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO MGI:4420993 (PMID:22932389) RGD PMID:22932389 NCBI chr 1:232,670,642...232,690,557
Ensembl chr 1:223,248,747...223,262,530
JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO (PMID:19666821) RGD PMID:19666821 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IDA PMID:9230312 MGI PMID:9230312 RGD:8553789 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:3653406 (PMID:20844123) RGD PMID:20844123 NCBI chr16:83,837,689...83,841,703
Ensembl chr16:77,137,584...77,138,762
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    multicellular organismal process 8969
      pattern specification process 492
        regionalization 446
          dorsal/ventral pattern formation 100
            spinal cord dorsal/ventral patterning 19
              negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 0
              smoothened signaling pathway involved in ventral spinal cord patterning + 3
              ventral spinal cord interneuron fate commitment + 12
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7109
      anatomical structure development 6611
        multicellular organism development 5330
          system development 4612
            nervous system development 2862
              central nervous system development 1216
                spinal cord development 143
                  spinal cord patterning 21
                    spinal cord dorsal/ventral patterning 19
                      negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 0
                      smoothened signaling pathway involved in ventral spinal cord patterning + 3
                      ventral spinal cord interneuron fate commitment + 12
paths to the root