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ONTOLOGY REPORT - ANNOTATIONS

Term:glutamate-gated receptor activity
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Accession:GO:0004970 term browser browse the term
Definition:Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'.
Synonyms:exact_synonym: ionotropic glutamate receptor activity


show annotations for term's descendants           Sort by:
glutamate-gated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 enables IDA
ISO		 (PMID:1699805)
PMID:11773314
PMID:1699275
PMID:1709304
PMID:2480522
PMID:2166337		 RGD PMID:1699805 PMID:17409242 PMID:11773314 PMID:1699275 PMID:1709304 More... RGD:4107730, RGD:401966871, RGD:728417, RGD:401966868, RGD:728518, RGD:728438 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 enables TAS
IEA
ISO
IDA		 GO_REF:0000107
(PMID:14687553)
PMID:21846932
PMID:19946266
(PMID:20614889)		 Ensembl
RGD		 PMID:14687553 PMID:20614889 PMID:12554656 PMID:21846932 PMID:19946266 GO_REF:0000107, RGD:728773, RGD:8553303, RGD:8553832 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 enables IDA
ISO		 PMID:1699567
PMID:2166337
PMID:2168579
(PMID:17989220)		 RGD PMID:17989220 PMID:11834304 PMID:1699567 PMID:2166337 PMID:2168579 RGD:728843, RGD:61621, RGD:728438, RGD:728514 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 enables IDA PMID:19102704
PMID:12603841
PMID:2166337
PMID:1372042
PMID:20107073		 UniProt PMID:19102704 PMID:12603841 PMID:2166337 PMID:1372042 PMID:20107073 RGD:8554524, RGD:405650329, RGD:728438, RGD:405650319, RGD:8554240 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 enables IDA
ISO		 PMID:1322826
PMID:25139762
PMID:9254673
(PMID:8730589)
(PMID:8589992)		 RGD PMID:8589992 PMID:8730589 PMID:17395219 PMID:1322826 PMID:25139762 More... RGD:1642466, RGD:727533, RGD:405650335, RGD:405650255 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 enables TAS
ISO
IDA		 (PMID:16354929), (PMID:31474366)
PMID:8163463
PMID:25139762
PMID:1322826
(PMID:14511640), (PMID:34375587), (PMID:7536611), (PMID:8730589)		 RGD PMID:7536611 PMID:8730589 PMID:14511640 PMID:16354929 PMID:31474366 More... RGD:69852, RGD:405650365, RGD:405650335, RGD:727533 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 enables IMP
IDA
ISO		 PMID:21907808
PMID:1371217
PMID:1322826
PMID:11124978
(PMID:11124978)		 RGD PMID:11124978 PMID:21907808 PMID:1371217 PMID:1322826 PMID:11124978 RGD:8553493, RGD:70754, RGD:727533, RGD:8553521 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 contributes_to TAS
IDA		 PMID:9390526
PMID:25139762		 RGD
UniProt		 PMID:7527545 PMID:9390526 PMID:25139762 RGD:734533, RGD:728668, RGD:405650335 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 contributes_to ISO
IDA		 (PMID:14511640), (PMID:8730589)
PMID:9254673
PMID:9390526
PMID:25139762		 RGD PMID:8730589 PMID:14511640 PMID:9254673 PMID:9390526 PMID:25139762 RGD:405650255, RGD:728668, RGD:405650335 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 TAS
IDA		 RGD PMID:12535174 PMID:16477151 RGD:727495, RGD:1642190 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A contributes_to IDA
IMP		 RGD PMID:16477151 PMID:19154422 PMID:19240037 RGD:1642190, RGD:2326036, RGD:2326029 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IDA RGD PMID:16477151 RGD:1642190 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C IDA RGD PMID:8428958 RGD:728651 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D enables IDA
ISO		 (PMID:27616483) RGD PMID:27616483 PMID:7512349 RGD:728580 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A TAS
IDA		 RGD PMID:9891978 PMID:16477151 RGD:632837, RGD:1642190 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
AMPA glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 enables IEA
ISO
IBA
IDA		 GO_REF:0000107
(PMID:29490264)
(PMID:1311100), (PMID:20805473), (PMID:21172611), (PMID:28628100), (PMID:35675825)
GO_REF:0000033
PMID:19265014		 Ensembl
RGD
GO_Central		 PMID:1311100 PMID:20805473 PMID:21172611 PMID:28628100 PMID:29490264 More... GO_REF:0000033 GO_REF:0000107, RGD:8554136 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 enables TAS
IBA
IDA		 GO_REF:0000033
PMID:19265014
PMID:21172611		 GO_Central
RGD		 PMID:12554656 PMID:19265014 PMID:21172611 GO_REF:0000033, RGD:728773, RGD:8554136, RGD:8554236 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 enables IDA
IBA
ISO
IEA		 GO_REF:0000033
(PMID:21172611)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:21172611 PMID:11834304 GO_REF:0000033 GO_REF:0000107, RGD:728843 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 enables TAS
IBA
IEA
ISO
IMP		 GO_REF:0000033
GO_REF:0000107
(PMID:21172611)		 GO_Central
Ensembl
RGD		 PMID:21172611 PMID:1699275 PMID:2166337 GO_REF:0000033 GO_REF:0000107, RGD:728417, RGD:728438 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
glutamate-gated calcium ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 enables IDA PMID:1709304
PMID:11773314		 UniProt PMID:1709304 PMID:11773314 RGD:401966868, RGD:401966871 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 enables IDA PMID:11773314 UniProt PMID:11773314 RGD:401966871 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 enables IDA PMID:1709304 UniProt PMID:1709304 RGD:401966868 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 enables IDA PMID:11425885
PMID:12873388		 UniProt PMID:11425885 PMID:12873388 RGD:405650374, RGD:405650399 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 enables IDA
ISO		 PMID:7681676
(PMID:20007474), (PMID:7681676)		 RGD PMID:7681676 PMID:20007474 PMID:7681676 RGD:405650269 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 enables IEA
ISO		 GO_REF:0000107
(PMID:20007474)		 Ensembl
RGD		 PMID:20007474 GO_REF:0000107 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 enables ISS
ISO		 GO_REF:0000024
(PMID:28126851), (PMID:7679115)		 UniProt
RGD		 PMID:7679115 PMID:28126851 GO_REF:0000024 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:26875626), (PMID:27839871)		 Ensembl
UniProt
RGD		 PMID:26875626 PMID:27839871 GO_REF:0000024 GO_REF:0000107 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B enables IEA
ISO
ISS		 GO_REF:0000107
(PMID:26875626), (PMID:27839871)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26875626 PMID:27839871 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D enables ISO
ISS		 (PMID:26875626)
GO_REF:0000024		 RGD
UniProt		 PMID:26875626 GO_REF:0000024 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
kainate selective glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 enables IDA PMID:21846932 UniProt PMID:21846932 RGD:8553303 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 enables IDA
ISO
IBA		 PMID:12873388
(PMID:9335499)
GO_REF:0000033
MGI:2176347|MGI:95815 (PMID:11985817), (PMID:12223554), (PMID:15483117), (PMID:15509753), (PMID:17174564)		 RGD
GO_Central		 PMID:9335499 PMID:11985817 PMID:12223554 PMID:15483117 PMID:15509753 More... GO_REF:0000033, RGD:1642466, RGD:405650399 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 enables IDA
ISO
IBA		 MGI:1857979|MGI:95814|MGI:95818 (PMID:10704492), (PMID:11985817), (PMID:12151522), (PMID:12223554), (PMID:1310861), (PMID:15483117), (PMID:15509753), (PMID:7681676), (PMID:9580260), (PMID:9880586)
(PMID:1379666)
GO_REF:0000033
(PMID:15537878)		 RGD
GO_Central		 PMID:1310861 PMID:1379666 PMID:7681676 PMID:9580260 PMID:9880586 More... GO_REF:0000033, RGD:69852, RGD:405650269 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 enables ISO
IBA
IEA		 (PMID:7719709)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:7719709 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 enables TAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7527545 GO_REF:0000033, RGD:734533 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 enables IDA
ISO
IBA
IEA		 MGI:95815 (PMID:1310861)
GO_REF:0000033
GO_REF:0000107
(PMID:1321949)		 RGD
GO_Central
Ensembl		 PMID:1310861 PMID:1321949 PMID:12080343 GO_REF:0000033 GO_REF:0000107, RGD:625595 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
NMDA glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 enables
contributes_to		 TAS
ISO
IDA
IGI
IMP		 (PMID:24272827), (PMID:26875626), (PMID:26919761), (PMID:27164704), (PMID:28095420), (PMID:28105280), (PMID:28126851), (PMID:28228639), (PMID:38538865), (PMID:7681588), (PMID:7685113), (PMID:9489750)
MGI:1928270|MGI:1928279|MGI:1928327|MGI:2387441|MGI:2448952|MGI:3611337|MGI:95820|MGI:95821|MGI:95822 (PMID:10963597), (PMID:12008020), (PMID:12040087), (PMID:12832526), (PMID:1374164), (PMID:1377365), (PMID:1385220), (PMID:14602821), (PMID:1532151), (PMID:15745956), (PMID:17313573), (PMID:7531804), (PMID:8060614), (PMID:8313466)
PMID:1350383
PMID:1388270
PMID:1834949
PMID:8428958
PMID:7929101
PMID:18177891
PMID:24876489
PMID:28384476
(PMID:7679115), (PMID:7685113)		 RGD PMID:1374164 PMID:1377365 PMID:1385220 PMID:1532151 PMID:7531804 More... RGD:727495, RGD:727540, RGD:407430004, RGD:407430007, RGD:728651, RGD:8553485, RGD:13432252, RGD:13432263, RGD:13432313, RGD:7241434, RGD:1642380, RGD:1642190 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A enables
contributes_to		 IDA
ISO
IBA
IEA
IMP		 (PMID:20890276), (PMID:23933819), (PMID:23933820), (PMID:24504326), (PMID:26875626), (PMID:26919761), (PMID:27288002), (PMID:28095420), (PMID:28126851), (PMID:28242877), (PMID:29644724), (PMID:36117210), (PMID:38307912), (PMID:38538865)
MGI:95819|RGD:2736 (PMID:1374164), (PMID:7929101)
MGI:1928285|MGI:1928506|MGI:95819 (PMID:11487658), (PMID:12754515), (PMID:1377365), (PMID:7816096), (PMID:8699248), (PMID:9427357), (PMID:9512392)
GO_REF:0000033
GO_REF:0000117
PMID:23625947
PMID:28384476		 RGD
GO_Central
UniProt		 PMID:1374164 PMID:1377365 PMID:7816096 PMID:7929101 PMID:8699248 More... GO_REF:0000033 GO_REF:0000117, RGD:728651, RGD:13432339, RGD:13432313, RGD:7241434, RGD:1642380, RGD:1642190 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B enables IDA
ISO
IBA
IEA		 (PMID:24272827), (PMID:26919761), (PMID:38538865)
MGI:1928293|MGI:1928295|MGI:95819|MGI:95823 (PMID:10634899), (PMID:12816890), (PMID:12832518), (PMID:1377365), (PMID:7531804), (PMID:9458051)
GO_REF:0000033
GO_REF:0000117
PMID:28384476
PMID:24876489		 RGD
GO_Central
UniProt		 PMID:1377365 PMID:7531804 PMID:9458051 PMID:10634899 PMID:12816890 More... GO_REF:0000033 GO_REF:0000117, RGD:727540, RGD:13432313, RGD:13432263, RGD:1642190 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C enables
contributes_to		 IDA
ISO
IBA
IEA		 PMID:1350383
(PMID:26875626), (PMID:26919761)
MGI:1928301|MGI:1928510|MGI:95819 (PMID:1377365), (PMID:8756432), (PMID:9427357), (PMID:9512392)
RGD:2736 (PMID:7929101)
GO_REF:0000033
GO_REF:0000117		 RGD
GO_Central
UniProt		 PMID:1377365 PMID:7929101 PMID:8756432 PMID:9427357 PMID:9512392 More... GO_REF:0000033 GO_REF:0000117, RGD:728651, RGD:727540 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D enables IDA
ISO
IBA
IMP		 (PMID:26875626), (PMID:26919761), (PMID:9489750)
MGI:1928298 (PMID:12832518), (PMID:1385220)
GO_REF:0000033
PMID:23625947		 RGD
GO_Central		 PMID:1385220 PMID:9489750 PMID:12832518 PMID:26875626 PMID:26919761 More... GO_REF:0000033, RGD:728580, RGD:13432339, RGD:1642397, RGD:1642380 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A enables
contributes_to		 TAS
ISO
IBA
IEA
IDA		 MGI:2387963|PR:P35438 (PMID:14507892), (PMID:9620802)
GO_REF:0000033
GO_REF:0000107
(PMID:17502428)
PMID:17182766		 RGD
GO_Central
Ensembl		 PMID:9620802 PMID:14507892 PMID:17502428 PMID:9891978 PMID:17182766 More... GO_REF:0000033 GO_REF:0000107, RGD:632837, RGD:8553928, RGD:1642190 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20626
    transporter activity 1253
      transmembrane transporter activity 1153
        amino acid transmembrane transporter activity 103
          glutamate-gated receptor activity 16
            AMPA glutamate receptor activity 4
            NMDA glutamate receptor activity 7
            glutamate-gated calcium ion channel activity 11
            kainate selective glutamate receptor activity 6
Path 2
Term Annotations click to browse term
  molecular_function 20626
    transporter activity 1253
      transmembrane transporter activity 1153
        passive transmembrane transporter activity 511
          channel activity 511
            gated channel activity 334
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 185
                  extracellular ligand-gated monoatomic ion channel activity 70
                    transmitter-gated monoatomic ion channel activity 60
                      glutamate-gated receptor activity 16
                        AMPA glutamate receptor activity 4
                        NMDA glutamate receptor activity 7
                        glutamate-gated calcium ion channel activity 11
                        kainate selective glutamate receptor activity 6
paths to the root