Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Cloning by functional expression of a member of the glutamate receptor family.

Authors: Hollmann, M  O'Shea-Greenfield, A  Rogers, SW  Heinemann, S 
Citation: Hollmann M, etal., Nature 1989 Dec 7;342(6250):643-8.
Pubmed: (View Article at PubMed) PMID:2480522
DOI: Full-text: DOI:10.1038/342643a0

We have isolated a complementary DNA clone by screening a rat brain cDNA library for expression of kainate-gated ion channels in Xenopus oocytes. The cDNA encodes a single protein of relative molecular mass (Mr) 99,800 which on expression in oocytes forms a functional ion channel possessing the electrophysiological and pharmacological properties of the kainate subtype of the glutamate receptor family in the mammalian central nervous system.


Objects referenced in this article

Additional Information

RGD Object Information
RGD ID: 728518
Created: 2003-11-19
Species: All species
Last Modified: 2003-11-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.