Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:DNA replication checkpoint signaling
go back to main search page
Accession:GO:0000076 term browser browse the term
Definition:A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
Synonyms:exact_synonym: DNA replication checkpoint;   signal transduction involved in DNA replication checkpoint
 alt_id: GO:0072437


show annotations for term's descendants           Sort by:
DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA		 (PMID:14672932)
(PMID:12192004)
GO_REF:0000033		 RGD
GO_Central		 PMID:12192004 PMID:14672932 GO_REF:0000033 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Clspn claspin acts_upstream_of_or_within ISO (PMID:12766152)
(PMID:16123041)		 RGD PMID:12766152 PMID:16123041 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISS
IEA		 GO_REF:0000024
GO_REF:0000107		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319 		JBrowse link
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000104		 GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21482717)		 UniProt
RGD		 PMID:21482717 GO_REF:0000024 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372 		JBrowse link
G Timeless timeless circadian regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tipin timeless interacting protein involved_in ISO
IBA
ISS
IEA		 (PMID:17102137)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000104		 RGD
GO_Central
UniProt		 PMID:17102137 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:21482717), (PMID:21777809) RGD PMID:21482717 PMID:21777809 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc6 cell division cycle 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (PMID:16885022)
GO_REF:0000033		 RGD
GO_Central		 PMID:16885022 GO_REF:0000033 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 involved_in ISO
IEA		 (PMID:10722740)
GO_REF:0000107		 RGD
Ensembl		 PMID:10722740 GO_REF:0000107 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Orc1 origin recognition complex, subunit 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:21191184)		 UniProt
GO_Central
RGD		 PMID:21191184 GO_REF:0000024 GO_REF:0000033 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      signal transduction 7181
        intracellular signal transduction 3074
          cell cycle checkpoint signaling 186
            DNA integrity checkpoint signaling 131
              DNA replication checkpoint signaling 18
                meiotic G2/MI DNA replication checkpoint signaling 0
                mitotic DNA replication checkpoint signaling 10
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        negative regulation of biological process 5767
          negative regulation of cellular process 5533
            negative regulation of cell cycle 401
              negative regulation of cell cycle process 314
                negative regulation of cell cycle phase transition 264
                  cell cycle checkpoint signaling 186
                    DNA integrity checkpoint signaling 131
                      DNA replication checkpoint signaling 18
                        meiotic G2/MI DNA replication checkpoint signaling 0
                        mitotic DNA replication checkpoint signaling 10
paths to the root