ONTOLOGY REPORT - ANNOTATIONS
Term: DNA replication checkpoint signaling
Accession: GO:0000076
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Definition: A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
Synonyms: exact_synonym: DNA replication checkpoint; signal transduction involved in DNA replication checkpoint
alt_id: GO:0072437
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Cdt1
chromatin licensing and DNA replication factor 1
involved_in
ISO IBA
(PMID:14672932) (PMID:12192004) GO_REF:0000033
RGD GO_Central
PMID:12192004 PMID:14672932
GO_REF:0000033
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
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Clspn
claspin
acts_upstream_of_or_within
ISO
(PMID:12766152) (PMID:16123041)
RGD
PMID:12766152 PMID:16123041
NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
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Dna2
DNA replication helicase/nuclease 2
involved_in
ISS IEA
GO_REF:0000024 GO_REF:0000107
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr20:25,661,652...25,690,598
Ensembl chr20:25,662,055...25,716,319
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LOC120094818
TIMELESS-interacting protein-like
involved_in
IBA IEA
GO_REF:0000033 GO_REF:0000104
GO_Central UniProt
GO_REF:0000033 GO_REF:0000104
NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
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Mdc1
mediator of DNA damage checkpoint 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:21482717)
UniProt RGD
PMID:21482717
GO_REF:0000024
NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
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Rad9a
RAD9 checkpoint clamp component A
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
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Rad9b
RAD9 checkpoint clamp component B
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372
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Timeless
timeless circadian regulator
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
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Tipin
timeless interacting protein
involved_in
ISO IBA ISS IEA
(PMID:17102137) GO_REF:0000033 GO_REF:0000024 GO_REF:0000104
RGD GO_Central UniProt
PMID:17102137
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104
NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352
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Tipinl1
TIMELESS interacting protein like 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
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Topbp1
DNA topoisomerase II binding protein 1
involved_in
ISO
(PMID:21482717), (PMID:21777809)
RGD
PMID:21482717 PMID:21777809
NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
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Cdc6
cell division cycle 6
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Clspn
claspin
involved_in
ISO IBA
(PMID:16885022) GO_REF:0000033
RGD GO_Central
PMID:16885022
GO_REF:0000033
NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
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Donson
DNA replication fork stabilization factor DONSON
involved_in
ISO
(PMID:28191891)
RGD
PMID:28191891
NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889
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Hus1
HUS1 checkpoint clamp component
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
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Nae1
NEDD8 activating enzyme E1 subunit 1
involved_in
ISO IEA
(PMID:10722740) GO_REF:0000107
RGD Ensembl
PMID:10722740
GO_REF:0000107
NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371
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Orc1
origin recognition complex, subunit 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
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Rad17
RAD17 checkpoint clamp loader component
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
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Ticrr
TOPBP1-interacting checkpoint and replication regulator
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
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Topbp1
DNA topoisomerase II binding protein 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
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Zfp830
zinc finger protein 830
involved_in
ISS IBA ISO
GO_REF:0000024 GO_REF:0000033 (PMID:21191184)
UniProt GO_Central RGD
PMID:21191184
GO_REF:0000024 GO_REF:0000033
NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
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