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ONTOLOGY REPORT - ANNOTATIONS

Term:cell cycle checkpoint
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Accession:GO:0000075 term browser browse the term
Definition:A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
Comment:This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
Synonyms:narrow_synonym: G1/S checkpoint;   G1/S transition checkpoint;   G2/M checkpoint;   G2/M transition checkpoint
 alt_id: GO:0031576;   GO:0071779
 xref: Wikipedia:Cell_cycle_checkpoint

show annotations for term's descendants           Sort by:
 
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO
IEA		 (PMID:18022368)
GO_REF:0000107		 RGD
Ensembl		 PMID:18022368 GO_REF:0000107 NCBI chr 9:17,217,141...17,221,465
Ensembl chr 9:17,216,495...17,221,434 		JBrowse link
detection of DNA damage stimulus involved in DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5562498|PMID:23993650) RGD PMID:23993650 MGI:5562498 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427 		JBrowse link
detection of stimulus involved in cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) RGD PMID:18045533 MGI:3818783 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427 		JBrowse link
DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2679752|PMID:12937170)
PMID:21873635		 RGD PMID:12937170, PMID:21873635, PMID:21873635 MGI:2679752, RGD:13792537, RGD:13792537 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Atr ATR serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:14657349)
(MGI:2679752|PMID:12937170)
PMID:21873635		 RGD PMID:12937170 PMID:14657349, PMID:21873635, PMID:21873635 MGI:2679752, RGD:13792537, RGD:13792537 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947 		JBrowse link
G Atrip ATR interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:117,797,954...117,811,989
Ensembl chr 8:117,797,842...117,811,975 		JBrowse link
G Cep63 centrosomal protein 63 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:111,063,988...111,116,014
Ensembl chr 8:111,064,049...111,116,014 		JBrowse link
G Chek1 checkpoint kinase 1 acts_upstream_of_or_within
involved_in		 ISS
ISO		 GO_REF:0000024
MGI:1926528 (MGI:1860049|PMID:10859164), (MGI:2449744|PMID:12529385)
(PMID:16963448), (PMID:19716789)		 UniProt
RGD		 PMID:10859164 PMID:12529385 PMID:16963448 PMID:19716789 GO_REF:0000024 MGI:1860049 MGI:2449744 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:10435585 RGD:633752 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624 		JBrowse link
G Clock clock circadian regulator involved_in ISO
IEA		 (PMID:21659603)
GO_REF:0000107		 RGD
Ensembl		 PMID:21659603 GO_REF:0000107 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218 		JBrowse link
G Clspn claspin involved_in ISO (PMID:16963448) RGD PMID:16963448 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:11,786,105...11,824,742
Ensembl chr 7:11,786,105...11,824,742 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO
ISS		 (PMID:12717439)
GO_REF:0000024		 RGD
UniProt		 PMID:12717439 GO_REF:0000024 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:110,159,624...110,245,382
Ensembl chr 3:110,159,708...110,249,217 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G H2ax H2A.X variant histone NOT|acts_upstream_of_or_within
involved_in		 ISO (PMID:17974976)
MGI:2156048 (MGI:2179182|PMID:11934988)		 RGD PMID:11934988 PMID:17974976 MGI:2179182 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Hinfp histone H4 transcription factor involved_in ISO (PMID:17974976) RGD PMID:17974976 NCBI chr 8:48,626,398...48,638,012
Ensembl chr 8:48,628,340...48,634,797 		JBrowse link
G Hus1 HUS1 checkpoint clamp component acts_upstream_of_or_within
involved_in		 ISO (PMID:21659603)
MGI:1927769 (MGI:2449744|PMID:12529385)		 RGD PMID:12529385 PMID:21659603 MGI:2449744 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825 		JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr13:110,257,571...110,310,413
Ensembl chr13:110,257,571...110,310,413 		JBrowse link
G LOC100911807 ATR-interacting protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:118,428,032...118,437,999
Ensembl chr 8:118,428,289...118,436,894 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:2679752|PMID:12937170)		 Ensembl
RGD		 PMID:12937170 GO_REF:0000107 MGI:2679752 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Nbn nibrin involved_in ISO (PMID:12529385) RGD PMID:12529385 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:2176524 (MGI:2679752|PMID:12937170) RGD PMID:12937170 MGI:2679752 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO
IBA		 (PMID:21659603)
PMID:21873635		 RGD PMID:21659603, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:60,461,513...60,469,646
Ensembl chr 2:60,461,551...60,469,685 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451 		JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in ISO
IBA		 (PMID:21659603)
PMID:21873635		 RGD PMID:21659603, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:161,679,674...161,685,060
Ensembl chr 4:161,680,027...161,681,660 		JBrowse link
G Tipin timeless interacting protein acts_upstream_of_or_within ISO (MGI:3706226|PMID:17141802) RGD PMID:17141802 MGI:3706226 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305 		JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO (PMID:17384681) RGD PMID:17384681 NCBI chr13:83,478,966...83,504,448
Ensembl chr13:83,478,974...83,504,494 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in IEA
IBA
ISO
ISS		 GO_REF:0000107
PMID:21873635
(PMID:18662541)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18662541, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 8:53,295,188...53,355,572
Ensembl chr 8:53,295,222...53,355,572 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO
IBA		 (PMID:21726810)
PMID:21873635		 RGD PMID:21726810, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:134,804,128...134,941,912
Ensembl chr 6:134,804,141...134,939,358 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:171,037,891...171,050,500
Ensembl chr 3:171,037,957...171,050,475 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO
IEA		 (PMID:16213212)
(MGI:5882892|PMID:16213212)
GO_REF:0000107		 RGD
Ensembl		 PMID:16213212 GO_REF:0000107 MGI:5882892 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in		 ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)		 RGD PMID:16107883 PMID:16213212 MGI:3589512 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
DNA replication checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA		 (PMID:14672932)
(MGI:2388867|PMID:12192004)
PMID:21873635		 RGD PMID:12192004 PMID:14672932, PMID:21873635, PMID:21873635 MGI:2388867, RGD:13792537, RGD:13792537 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511 		JBrowse link
G Clspn claspin involved_in ISO (PMID:12766152) RGD PMID:12766152 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22570476)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22570476 GO_REF:0000024 GO_REF:0000107
G Rad9a RAD9 checkpoint clamp component A involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:39,699,076...39,731,218
Ensembl chr12:39,699,181...39,729,516 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:27,283,383...27,308,069
Ensembl chr20:27,254,984...27,308,069 		JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628 		JBrowse link
G Tipin timeless interacting protein involved_in ISO
ISS
IEA
IBA		 (PMID:17102137)
GO_REF:0000024
GO_REF:0000104
PMID:21873635		 RGD
UniProt		 PMID:17102137, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000104, RGD:13792537, RGD:13792537 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305 		JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:173,761...174,959
Ensembl chr 5:173,744...174,921 		JBrowse link
G1 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) RGD PMID:21329877 NCBI chr17:60,887,606...60,946,630
Ensembl chr17:60,888,017...60,946,426 		JBrowse link
intra-S DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO
ISS		 (PMID:15916964)
GO_REF:0000024		 RGD
UniProt		 PMID:15916964 GO_REF:0000024 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:82,366,820...82,375,510
Ensembl chr10:82,367,084...82,374,171 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930 		JBrowse link
G Fancd2 FA complementation group D2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825 		JBrowse link
G LOC103690165 checkpoint protein HUS1B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:34,691,084...34,694,690
Ensembl chr17:34,693,597...34,694,690 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease acts_upstream_of_or_within
involved_in		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3027036 (MGI:2683367|PMID:14690604), (MGI:3805397|PMID:18614044)
PMID:21873635		 Ensembl
RGD		 PMID:14690604 PMID:18614044, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:2683367 MGI:3805397, RGD:13792537, RGD:13792537 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
MGI:103557 (MGI:3512823|PMID:15533840)		 Ensembl
RGD		 PMID:15533840 GO_REF:0000107 MGI:3512823 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:220,862,474...220,867,973
Ensembl chr 1:220,862,386...220,867,815 		JBrowse link
G Nek11 NIMA-related kinase 11 involved_in ISO
IBA		 (PMID:15161910)
PMID:21873635		 RGD PMID:15161910, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:113,703,406...113,937,097
Ensembl chr 8:113,787,128...113,937,097 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO
IEA		 (PMID:15538388)
GO_REF:0000107		 RGD
Ensembl		 PMID:15538388 GO_REF:0000107 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within
involved_in		 ISO
IBA		 UniProtKB:P26306 (MGI:1289930|PMID:9766521)
PMID:21873635		 RGD PMID:9766521, PMID:21873635, PMID:21873635 MGI:1289930, RGD:13792537, RGD:13792537 NCBI chr 1:219,443,347...219,450,574
Ensembl chr 1:219,444,092...219,450,451 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:39,699,076...39,731,218
Ensembl chr12:39,699,181...39,729,516 		JBrowse link
G Tipin timeless interacting protein involved_in ISO
ISS		 (PMID:17102137)
GO_REF:0000024		 RGD
UniProt		 PMID:17102137 GO_REF:0000024 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:101816 (MGI:3512823|PMID:15533840) RGD PMID:15533840 MGI:3512823 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985 		JBrowse link
meiotic cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsun2 NOP2/Sun RNA methyltransferase 2 involved_in ISO (MGI:5525987|PMID:23401851) RGD PMID:23401851 MGI:5525987 NCBI chr 1:36,295,650...36,319,906
Ensembl chr 1:36,295,650...36,319,966 		JBrowse link
meiotic DNA integrity checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hus1 HUS1 checkpoint clamp component involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825 		JBrowse link
G LOC103690165 checkpoint protein HUS1B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:34,691,084...34,694,690
Ensembl chr17:34,693,597...34,694,690 		JBrowse link
meiotic recombination checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hormad1 HORMA domain containing 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
(MGI:4868505|PMID:21079677), (MGI:5009722|PMID:21478856)
MGI:5587823 (MGI:5586966|PMID:22530760)
PMID:21873635
MGI:5587823 (MGI:4868505|PMID:21079677), (MGI:5009722|PMID:21478856), (MGI:5586966|PMID:22530760)		 UniProt
RGD		 PMID:21079677 PMID:21478856 PMID:22530760, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:4868505 MGI:5009722 MGI:5586966, RGD:13792537, RGD:13792537 NCBI chr 2:197,681,820...197,720,197
Ensembl chr 2:197,682,000...197,719,254 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO UniProtKB:P22193 (PMID:9716408) RGD PMID:9716408 NCBI chr 2:60,461,513...60,469,646
Ensembl chr 2:60,461,551...60,469,685 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919 		JBrowse link
meiotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5056148 (MGI:5049806|PMID:21558374)
PMID:21873635		 RGD PMID:21558374, PMID:21873635, PMID:21873635 MGI:5049806, RGD:13792537, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993 		JBrowse link
meiotic spindle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chfr checkpoint with forkhead and ring finger domains involved_in ISO
IEA		 (PMID:10935642)
GO_REF:0000107		 RGD
Ensembl		 PMID:10935642 GO_REF:0000107 NCBI chr12:52,562,594...52,596,162
Ensembl chr12:52,562,597...52,596,076 		JBrowse link
mitotic cytokinesis checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991 		JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22422861), (PMID:24814515)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22422861 PMID:24814515 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO
ISS		 (PMID:24814515)
GO_REF:0000024		 RGD
UniProt		 PMID:24814515 GO_REF:0000024 NCBI chr19:39,230,050...39,243,298
Ensembl chr19:39,229,754...39,243,496 		JBrowse link
G Zfyve19 zinc finger FYVE-type containing 19 involved_in ISO
IBA		 (PMID:24814515)
PMID:21873635		 RGD PMID:24814515, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:111,013,856...111,021,841
Ensembl chr 3:111,013,856...111,021,841 		JBrowse link
mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624 		JBrowse link
G Stk33 serine/threonine kinase 33 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:173,872,744...174,051,768
Ensembl chr 1:173,872,736...174,047,572 		JBrowse link
G Zfp830 zinc finger protein 830 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3583779 (MGI:5428139|PMID:23213458)
PMID:21873635		 RGD PMID:23213458, PMID:21873635, PMID:21873635 MGI:5428139, RGD:13792537, RGD:13792537 NCBI chr10:70,118,250...70,119,714
Ensembl chr10:70,118,250...70,119,716 		JBrowse link
mitotic DNA integrity checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Setmar SET domain and mariner transposase fusion gene involved_in ISO (PMID:18790802) RGD PMID:18790802 NCBI chr 4:140,092,346...140,104,495
Ensembl chr 4:140,092,352...140,105,316 		JBrowse link
G Top2a DNA topoisomerase II alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154 		JBrowse link
mitotic DNA replication checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049960.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 5:146,294,030...146,296,221 JBrowse link
G Cdc6 cell division cycle 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (PMID:16885022)
PMID:21873635		 RGD PMID:16885022, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr14:89,194,086...89,208,825
Ensembl chr14:89,194,092...89,208,825 		JBrowse link
G LOC103690165 checkpoint protein HUS1B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr17:34,691,084...34,694,690
Ensembl chr17:34,693,597...34,694,690 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:10722740)		 Ensembl
RGD		 PMID:10722740 GO_REF:0000107 NCBI chr19:653,510...680,378
Ensembl chr19:653,510...680,378 		JBrowse link
G Orc1 origin recognition complex, subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:128,186,651...128,212,901
Ensembl chr 5:128,190,708...128,210,445 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:141,391,738...141,433,615
Ensembl chr 1:141,391,262...141,433,109 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:111,790,655...111,835,224
Ensembl chr 8:111,790,678...111,827,151 		JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4950701|PMID:21191184)
PMID:21873635		 UniProt
RGD		 PMID:21191184, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:4950701, RGD:13792537, RGD:13792537 NCBI chr10:70,118,250...70,119,714
Ensembl chr10:70,118,250...70,119,716 		JBrowse link
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISO
ISS		 (PMID:19412162)
GO_REF:0000024		 RGD
UniProt		 PMID:19412162 GO_REF:0000024 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO UniProtKB:P06400 (PMID:16286473) RGD PMID:16286473 NCBI chr 3:80,844,002...80,886,487
Ensembl chr 3:80,844,005...80,875,817 		JBrowse link
G Fbxo31 F-box protein 31 involved_in IEA
ISO
ISS		 GO_REF:0000002
(PMID:19412162)
GO_REF:0000024		 InterPro
RGD
UniProt		 PMID:19412162 GO_REF:0000002 GO_REF:0000024 NCBI chr19:53,487,610...53,625,673
Ensembl chr19:53,487,613...53,625,673 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO MGI:4126459 (MGI:4366664|PMID:19744960) RGD PMID:19744960 MGI:4366664 NCBI chr 9:94,425,191...94,550,431
Ensembl chr 9:94,425,252...94,550,431 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) RGD PMID:20173098 NCBI chr19:42,960,597...42,971,894
Ensembl chr19:42,964,586...42,972,101 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within
involved_in		 ISO (PMID:7958916)
(MGI:3589512|PMID:16107883)		 RGD PMID:7958916 PMID:16107883 MGI:3589512 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
mitotic G1/S transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plk3 polo-like kinase 3 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5142362|PMID:21376736)
PMID:21873635		 UniProt
RGD		 PMID:21376736, PMID:21873635, PMID:21873635 GO_REF:0000024 MGI:5142362, RGD:13792537, RGD:13792537 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900 		JBrowse link
G Plk5 polo-like kinase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:12,212,910...12,234,253
Ensembl chr 7:12,212,911...12,221,330 		JBrowse link
mitotic G2 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049960.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr 5:146,294,030...146,296,221 JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) RGD PMID:11309417 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) RGD PMID:15150265 NCBI chr 1:72,701,281...72,727,061
Ensembl chr 1:72,701,610...72,727,112 		JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISS PMID:15150265 UniProt PMID:15150265, PMID:15150265 RGD:8554801, RGD:8554801 NCBI chr 1:214,918,757...214,940,883
Ensembl chr 1:214,927,172...214,947,624 		JBrowse link
G Ccng1 cyclin G1 IMP RGD PMID:9464250 RGD:2316029 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:2679752|PMID:12937170)
PMID:21873635		 RGD PMID:12937170, PMID:21873635, PMID:21873635 MGI:2679752, RGD:13792537, RGD:13792537 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15790566)		 Ensembl
UniProt
RGD		 PMID:15790566 GO_REF:0000024 GO_REF:0000107 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) RGD PMID:23213251 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (PMID:18662541)
PMID:21873635		 RGD PMID:18662541, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490 		JBrowse link
G Foxn3 forkhead box N3 involved_in ISO UniProtKB:P38111 (PMID:9154802) RGD PMID:9154802 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695 		JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (MGI:2183145|PMID:12048180) RGD PMID:12048180 MGI:2183145 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS		 (PMID:16061642)
GO_REF:0000024		 RGD
UniProt		 PMID:16061642 GO_REF:0000024 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:5432078|PMID:20467439) RGD PMID:20467439 MGI:5432078 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in ISO (MGI:4455105|PMID:20154723) RGD PMID:20154723 MGI:4455105 NCBI chr 1:206,324,763...206,417,143
Ensembl chr 1:206,324,765...206,417,143 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase acts_upstream_of_or_within ISO MGI:2684310 (MGI:2682526|PMID:14614141) RGD PMID:14614141 MGI:2682526 NCBI chr 4:147,744,673...147,756,462
Ensembl chr 4:147,746,186...147,756,294 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease acts_upstream_of_or_within
involved_in		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3027036 (MGI:2683367|PMID:14690604)
PMID:21873635		 Ensembl
RGD		 PMID:14690604, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:2683367, RGD:13792537, RGD:13792537 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:35,680,687...35,704,685
Ensembl chr10:35,680,658...35,704,776 		JBrowse link
G Nbn nibrin acts_upstream_of_or_within
involved_in		 IEA
ISO
ISS
IBA		 GO_REF:0000107
MGI:2183796 (MGI:3805397|PMID:18614044)
GO_REF:0000024
(PMID:11438675)
PMID:21873635		 Ensembl
RGD
UniProt		 PMID:11438675 PMID:18614044, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3805397, RGD:13792537, RGD:13792537 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) RGD PMID:21741933 NCBI chr 1:77,836,522...77,843,991
Ensembl chr 1:77,836,196...77,844,189 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor acts_upstream_of_or_within ISO MGI:3904866 (MGI:5435138|PMID:22448250) RGD PMID:22448250 MGI:5435138 NCBI chr 5:153,269,638...153,277,562
Ensembl chr 5:153,269,526...153,277,563 		JBrowse link
G Taok1 TAO kinase 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17396146)		 Ensembl
UniProt
RGD		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155 		JBrowse link
G Taok2 TAO kinase 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17396146)		 Ensembl
UniProt
RGD		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075 		JBrowse link
G Taok3 TAO kinase 3 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17396146)		 Ensembl
UniProt
RGD		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:45,037,951...45,116,593
Ensembl chr12:45,037,883...45,182,974 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:141,391,738...141,433,615
Ensembl chr 1:141,391,262...141,433,109 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 8:111,790,655...111,835,224
Ensembl chr 8:111,790,678...111,827,151 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23213251)		 UniProt
RGD		 PMID:23213251 GO_REF:0000024 NCBI chr20:2,500,691...2,514,546
Ensembl chr20:2,500,689...2,514,546 		JBrowse link
mitotic G2/M transition checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated acts_upstream_of_or_within
involved_in		 IEA
ISO		 GO_REF:0000107
(MGI:3052267|PMID:15254237)		 Ensembl
RGD		 PMID:15254237 GO_REF:0000107 MGI:3052267 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO
ISS		 (PMID:19223857)
GO_REF:0000024		 RGD
UniProt		 PMID:19223857 GO_REF:0000024 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO
ISS		 (PMID:33108758)
GO_REF:0000024		 RGD
UniProt		 PMID:33108758 GO_REF:0000024 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Ints3 integrator complex subunit 3 involved_in ISO
IEA		 (PMID:19683501)
GO_REF:0000107		 RGD
Ensembl		 PMID:19683501 GO_REF:0000107 NCBI chr 2:189,766,927...189,818,327
Ensembl chr 2:189,766,735...189,818,224 		JBrowse link
G Nabp1 nucleic acid binding protein 1 involved_in ISO
ISS		 (PMID:19683501)
GO_REF:0000024		 RGD
UniProt		 PMID:19683501 GO_REF:0000024 NCBI chr 9:55,049,893...55,057,784
Ensembl chr 9:55,050,203...55,057,658 		JBrowse link
G Nabp2 nucleic acid binding protein 2 involved_in ISO
IEA
ISS		 (PMID:19683501)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19683501 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:2,820,006...2,825,627
Ensembl chr 7:2,820,007...2,825,608 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO
ISS		 (PMID:33108758)
GO_REF:0000024		 RGD
UniProt		 PMID:33108758 GO_REF:0000024 NCBI chr 1:242,372,458...242,373,764
Ensembl chr 1:242,372,458...242,373,764 		JBrowse link
mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in ISO
IEA		 (PMID:17227893)
GO_REF:0000107		 RGD
Ensembl		 PMID:17227893 GO_REF:0000107 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) RGD PMID:11943150 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Aurkb aurora kinase B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12805209)		 UniProt
RGD		 PMID:12805209 GO_REF:0000024 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:2673075 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747 		JBrowse link
G Ik IK cytokine involved_in ISO
ISS		 (PMID:22351768)
GO_REF:0000024		 RGD
UniProt		 PMID:22351768 GO_REF:0000024 NCBI chr18:29,587,901...29,602,705
Ensembl chr18:29,587,901...29,608,338 		JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member acts_upstream_of_or_within ISO MGI:3844604 (MGI:3844372|PMID:19376971) RGD PMID:19376971 MGI:3844372 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592 		JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISO
IEA
ISS
IBA		 (PMID:23455478)
GO_REF:0000107
GO_REF:0000024
PMID:21873635		 RGD
Ensembl
UniProt		 PMID:23455478, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr11:87,646,489...87,718,808
Ensembl chr11:87,677,966...87,718,826 		JBrowse link
G Kntc1 kinetochore associated 1 involved_in ISO
IEA		 (PMID:11146660)
GO_REF:0000107		 RGD
Ensembl		 PMID:11146660 GO_REF:0000107 NCBI chr12:38,200,463...38,274,162
Ensembl chr12:38,200,463...38,274,036 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO
IBA		 (PMID:18981471)
PMID:21873635		 RGD PMID:18981471, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr12:16,410,083...16,721,232
Ensembl chr12:16,410,083...16,719,824 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:18981471)
MGI:2178781 (MGI:1930685|PMID:11201745)
PMID:21873635		 RGD PMID:11201745 PMID:18981471, PMID:21873635, PMID:21873635 MGI:1930685, RGD:13792537, RGD:13792537 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:23455478)		 Ensembl
UniProt
RGD		 PMID:23455478 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989 		JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (MGI:2388532|PMID:12147697) RGD PMID:12147697 MGI:2388532 NCBI chr18:63,394,991...63,420,491
Ensembl chr18:63,394,900...63,409,600 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:19,628,070...19,652,914
Ensembl chr10:19,628,258...19,652,898 		JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor involved_in IEA
ISO
IBA
ISS		 GO_REF:0000107
(MGI:5318128|PMID:22405274)
PMID:21873635
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22405274, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5318128, RGD:13792537, RGD:13792537 NCBI chr10:74,724,070...74,849,172
Ensembl chr10:74,724,549...74,849,194 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:20133940)		 UniProt
RGD		 PMID:20133940 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO
ISS		 (PMID:28553959)
GO_REF:0000024		 RGD
UniProt		 PMID:28553959 GO_REF:0000024 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919 		JBrowse link
G Ttk Ttk protein kinase involved_in ISO
IBA		 MGI:5056148 (MGI:5608719|PMID:25197064)
PMID:21873635		 RGD PMID:25197064, PMID:21873635, PMID:21873635 MGI:5608719, RGD:13792537, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993 		JBrowse link
G Zfp207 zinc finger protein 207 involved_in ISO
IBA		 (PMID:24462186), (PMID:24462187)
PMID:21873635		 RGD PMID:24462186 PMID:24462187, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr10:67,762,970...67,784,854
Ensembl chr10:67,762,995...67,774,787 		JBrowse link
G Zw10 zw10 kinetochore protein involved_in IBA
ISO
ISS		 PMID:21873635
(PMID:11146660)
GO_REF:0000024		 RGD
HGNC-UCL		 PMID:11146660, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 8:53,365,881...53,390,742
Ensembl chr 8:53,365,857...53,390,930 		JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO
IEA		 (PMID:15485811)
GO_REF:0000107		 RGD
Ensembl		 PMID:15485811 GO_REF:0000107 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766 		JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055 		JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624 		JBrowse link
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:48,196,789...48,213,506
Ensembl chr  X:48,196,916...48,213,505 		JBrowse link
G Ddx39b DExD-box helicase 39B involved_in ISO
ISS		 (PMID:22144908)
GO_REF:0000024		 RGD
UniProt		 PMID:22144908 GO_REF:0000024 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568 		JBrowse link
G Thoc1 THO complex 1 involved_in ISO (PMID:22144908) RGD PMID:22144908 NCBI chr18:1,142,540...1,177,084
Ensembl chr18:1,142,782...1,176,974 		JBrowse link
G Thoc5 THO complex 5 involved_in ISO
ISS		 (PMID:22144908)
GO_REF:0000024		 RGD
UniProt		 PMID:22144908 GO_REF:0000024 NCBI chr14:85,138,219...85,171,729
Ensembl chr14:85,142,279...85,171,726 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q15554 (PMID:23426265)		 Ensembl
RGD		 PMID:23426265 GO_REF:0000107 NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286 		JBrowse link
positive regulation of cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prox1 prospero homeobox 1 acts_upstream_of_or_within ISO (MGI:4946187|PMID:21040746) RGD PMID:21040746 MGI:4946187 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:51,818,887...51,834,443
Ensembl chr15:51,818,897...51,834,030 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19229290)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19229290 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 involved_in ISO (MGI:4839685|PMID:20870947)
(PMID:20870947), (PMID:8824189)		 RGD PMID:8824189 PMID:20870947 MGI:4839685 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947)
(MGI:4839685|PMID:20870947)		 RGD PMID:20870947 MGI:4839685 NCBI chr16:81,757,582...81,783,047
Ensembl chr16:81,756,971...81,783,047 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:18981471), (PMID:19273613)		 UniProt
RGD		 PMID:18981471 PMID:19273613 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) RGD PMID:15342622 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369 		JBrowse link
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5567851|PMID:24489120)		 UniProt
RGD		 PMID:24489120 GO_REF:0000024 MGI:5567851 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097 		JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO MGI:3851025 (MGI:3850765|PMID:19481525) RGD PMID:19481525 MGI:3850765 NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO
IBA		 (PMID:27723717), (PMID:27723720)
PMID:21873635		 RGD PMID:27723717 PMID:27723720, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677 		JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO MGI:5301830 (MGI:5299398|PMID:21911473) RGD PMID:21911473 MGI:5299398 NCBI chr 2:53,797,954...53,811,134
Ensembl chr 2:53,797,954...53,811,134 		JBrowse link
G Fem1b fem-1 homolog B involved_in ISO
ISS		 (PMID:19330022)
GO_REF:0000024		 RGD
UniProt		 PMID:19330022 GO_REF:0000024 NCBI chr 8:67,695,041...67,708,313
Ensembl chr 8:67,694,904...67,708,304 		JBrowse link
G Nek1 NIMA-related kinase 1 involved_in ISO (MGI:5619475|PMID:18843199) RGD PMID:18843199 MGI:5619475 NCBI chr16:32,321,010...32,439,421
Ensembl chr16:32,321,010...32,439,421 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:21504906) RGD PMID:21504906 NCBI chr19:42,960,597...42,971,894
Ensembl chr19:42,964,586...42,972,101 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B acts_upstream_of_or_within ISO MGI:4432164 (MGI:5435090|PMID:22802351) RGD PMID:22802351 MGI:5435090 NCBI chr15:45,422,010...45,472,792
Ensembl chr15:45,422,010...45,464,892 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS		 (PMID:21504906)
GO_REF:0000024		 RGD
UniProt		 PMID:21504906 GO_REF:0000024 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269 		JBrowse link
G Wdr76 WD repeat domain 76 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 3:113,445,498...113,479,483
Ensembl chr 3:113,448,877...113,478,215 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO
ISS
IBA		 (PMID:21926987)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:21926987, PMID:21873635, PMID:21873635 GO_REF:0000024, RGD:13792537, RGD:13792537 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054 		JBrowse link
G Ccnb1 cyclin B1 involved_in ISO (PMID:18195732) RGD PMID:18195732 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19282672)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19282672 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102 		JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 involved_in ISO
IEA		 (PMID:17724024)
GO_REF:0000107		 RGD
Ensembl		 PMID:17724024 GO_REF:0000107 NCBI chr 1:193,335,629...193,391,620
Ensembl chr 1:193,335,645...193,391,638 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) RGD PMID:21853124 MGI:5448515 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206 		JBrowse link
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rint1 RAD50 interactor 1 involved_in ISO
IBA		 (PMID:11096100)
PMID:21873635		 RGD PMID:11096100, PMID:21873635 RGD:13792537 NCBI chr 4:7,851,602...7,885,446
Ensembl chr 4:7,852,224...7,885,301 		JBrowse link
signal transduction involved in cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox11 SRY-box transcription factor 11 involved_in ISO (PMID:20624318) RGD PMID:20624318 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983 		JBrowse link
signal transduction involved in DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc5l cell division cycle 5-like involved_in ISO
ISS		 (PMID:24332808)
GO_REF:0000024		 RGD
UniProt		 PMID:24332808 GO_REF:0000024 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISO
ISS		 (PMID:24332808)
GO_REF:0000024		 RGD
UniProt		 PMID:24332808 GO_REF:0000024 NCBI chr 1:226,947,065...226,958,147
Ensembl chr 1:226,947,105...226,958,144 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:3818783|PMID:18045533) RGD PMID:18045533 MGI:3818783 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427 		JBrowse link
signal transduction involved in G2 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17525340), (PMID:17643121), (PMID:19261748)		 Ensembl
UniProt
RGD		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr14:10,424,674...10,439,010
Ensembl chr14:10,424,674...10,439,003 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19261746), (PMID:19261748), (PMID:19261749)		 UniProt
RGD		 PMID:19261746 PMID:19261748 PMID:19261749 GO_REF:0000024 NCBI chr16:19,792,720...19,798,886
Ensembl chr16:19,792,838...19,798,894 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISO
ISS		 (PMID:19261748)
GO_REF:0000024		 RGD
UniProt		 PMID:19261748 GO_REF:0000024 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in IEA
ISO		 GO_REF:0000107
(PMID:17525340), (PMID:17643121), (PMID:19261748)		 Ensembl
RGD		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000107 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17525341), (PMID:19261746), (PMID:19261748)		 UniProt
RGD		 PMID:17525341 PMID:19261746 PMID:19261748 GO_REF:0000024 NCBI chr 9:9,863,380...9,865,920
Ensembl chr 9:9,863,404...9,865,920 		JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) RGD PMID:20932473 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:17085480) RGD PMID:17085480 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr 7:11,201,690...11,213,614
Ensembl chr 7:11,201,690...11,213,613 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:18662541)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18662541 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr17:10,061,915...10,130,921
Ensembl chr17:10,065,947...10,130,907 		JBrowse link
signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:11298456) RGD PMID:11298456 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624 		JBrowse link
signal transduction involved in mitotic cell cycle checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zw10 zw10 kinetochore protein involved_in ISO
IEA		 (PMID:15824131)
GO_REF:0000107		 RGD
Ensembl		 PMID:15824131 GO_REF:0000107 NCBI chr 8:53,365,881...53,390,742
Ensembl chr 8:53,365,857...53,390,930 		JBrowse link
G Zwilch zwilch kinetochore protein involved_in ISO
IEA		 (PMID:15824131)
GO_REF:0000107		 RGD
Ensembl		 PMID:15824131 GO_REF:0000107 NCBI chr 8:69,089,449...69,121,420
Ensembl chr 8:69,091,955...69,121,192 		JBrowse link
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871 		JBrowse link
signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    cellular process 18900
      cell cycle checkpoint 174
        DNA integrity checkpoint + 125
        detection of stimulus involved in cell cycle checkpoint + 1
        meiotic cell cycle checkpoint + 8
        mitotic cell cycle checkpoint + 120
        negative regulation of cell cycle checkpoint + 9
        positive regulation of cell cycle checkpoint + 10
        regulation of cell cycle checkpoint + 35
        signal transduction involved in cell cycle checkpoint + 33
        spindle checkpoint + 38
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of cellular process 12625
          negative regulation of cellular process 5183
            negative regulation of cell cycle 456
              cell cycle checkpoint 174
                DNA integrity checkpoint + 125
                detection of stimulus involved in cell cycle checkpoint + 1
                meiotic cell cycle checkpoint + 8
                mitotic cell cycle checkpoint + 120
                negative regulation of cell cycle checkpoint + 9
                positive regulation of cell cycle checkpoint + 10
                regulation of cell cycle checkpoint + 35
                signal transduction involved in cell cycle checkpoint + 33
                spindle checkpoint + 38
paths to the root