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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:mirex
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Accession:CHEBI:34852 term browser browse the term
Definition:A chlorocarbon that has formula C10Cl12.
Synonyms:exact_synonym: 1,1a,2,2,3,3a,4,5,5,5a,5b,6-dodecachlorooctahydro-1H-1,3,4-(methanetriyl)cyclobuta[cd]pentalene
 related_synonym: 1,2,3,4,5,5,6,7,8,9,10,10-dodecachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decane;   CG-1283;   Dechlorane;   Formula=C10Cl12;   InChI=1S/C10Cl12/c11-1-2(12)7(17)4(14)3(13,5(1,15)9(7,19)20)6(1,16)10(21,22)8(2,4)18;   InChIKey=GVYLCNUFSHDAAW-UHFFFAOYSA-N;   SMILES=ClC1(Cl)C2(Cl)C3(Cl)C4(Cl)C(Cl)(Cl)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl;   dodecachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalene;   perchlorodihomocubane;   perchloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decane;   perchloropentacyclodecane
 xref: Beilstein:2010845;   CAS:2385-85-5;   Gmelin:1789502;   HMDB:HMDB0059573;   KEGG:C14184
 xref_mesh: MESH:D008917
 xref: PPDB:1294;   Patent:US2702305;   Patent:US2724730;   Reaxys:2010845;   Wikipedia:Mirex


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mirex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP-binding cassette, sub-family C member 6 decreases expression ISO Mirex results in decreased expression of ABCC6 mRNA CTD PMID:23153324 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Mirex results in increased expression of ABCG5 mRNA CTD PMID:23153324 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439 		JBrowse link
G Aqp9 aquaporin 9 decreases expression ISO Mirex results in decreased expression of AQP9 mRNA CTD PMID:23153324 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964 		JBrowse link
G Ar androgen receptor multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Hydrocarbons, Chlorinated] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21295777 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide decreases expression ISO Mirex results in decreased expression of ATP1B1 mRNA CTD PMID:23153324 NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924 		JBrowse link
G Atp2c1 ATPase, Ca++-sequestering decreases expression ISO Mirex results in decreased expression of ATP2C1 mRNA CTD PMID:23153324 NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518 		JBrowse link
G Bcat1 branched chain aminotransferase 1, cytosolic increases expression ISO Mirex results in increased expression of BCAT1 mRNA CTD PMID:23153324 NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910 		JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Mirex results in increased expression of CCNB1 mRNA CTD PMID:23153324 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Mirex results in increased expression of CCNB2 mRNA CTD PMID:23153324 NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829 		JBrowse link
G Cdkn3 cyclin dependent kinase inhibitor 3 increases expression ISO Mirex results in increased expression of CDKN3 mRNA CTD PMID:23153324 NCBI chr14:46,997,912...47,008,987
Ensembl chr14:46,997,998...47,009,126 		JBrowse link
G Cenpe centromere protein E increases expression ISO Mirex results in increased expression of CENPE mRNA CTD PMID:23153324 NCBI chr 3:134,918,324...134,979,301
Ensembl chr 3:134,918,298...134,979,372 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit decreases expression ISO Mirex results in decreased expression of CHRNA1 mRNA CTD PMID:23153324 NCBI chr 2:73,393,625...73,410,682
Ensembl chr 2:73,393,559...73,410,682 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) increases expression ISO Mirex results in increased expression of CSF3 mRNA CTD PMID:23153324 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions EXP Mirex results in increased expression of and results in increased activity of CYP2B10 protein CTD PMID:8722114 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression ISO Mirex results in increased expression of CYP2B2 mRNA; Mirex results in increased expression of CYP2B2 protein CTD PMID:1715015 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO Mirex results in decreased expression of CYP2E1 protein CTD PMID:3113478 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Ect2 ect2 oncogene increases expression ISO Mirex results in increased expression of ECT2 mRNA CTD PMID:23153324 NCBI chr 3:27,151,371...27,207,971
Ensembl chr 3:27,151,371...27,208,027 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 increases expression ISO Mirex results in increased expression of ELOVL7 mRNA CTD PMID:23153324 NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217 		JBrowse link
G Ereg epiregulin increases expression ISO Mirex results in increased expression of EREG mRNA CTD PMID:23153324 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA CTD PMID:21295777 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Mirex results in increased expression of HK2 mRNA CTD PMID:23153324 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435 		JBrowse link
G Kif18b kinesin family member 18B increases expression ISO Mirex results in increased expression of KIF18B mRNA CTD PMID:23153324 NCBI chr11:102,796,344...102,815,960
Ensembl chr11:102,796,355...102,815,950 		JBrowse link
G Lmnb1 lamin B1 increases expression ISO Mirex results in increased expression of LMNB1 mRNA CTD PMID:23153324 NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 increases expression ISO Mirex results in increased expression of LRRC1 mRNA CTD PMID:23153324 NCBI chr 9:77,338,103...77,453,749
Ensembl chr 9:77,338,105...77,452,152 		JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression ISO Mirex results in increased expression of MEOX2 mRNA CTD PMID:23153324 NCBI chr12:37,158,539...37,229,533
Ensembl chr12:37,158,539...37,229,533 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Mirex results in increased expression of MMD mRNA CTD PMID:23153324 NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression ISO Mirex results in decreased expression of NNT mRNA CTD PMID:23153324 NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533
Ensembl chr13:119,471,984...119,545,533 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Mirex results in decreased expression of NR3C1 protein CTD PMID:1638671 PMID:1673321 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 increases expression ISO Mirex results in increased expression of NT5DC2 mRNA CTD PMID:23153324 NCBI chr14:30,853,046...30,861,081
Ensembl chr14:30,853,010...30,861,081 		JBrowse link
G Odc1 ornithine decarboxylase, structural 1 increases activity ISO Mirex results in increased activity of ODC1 protein CTD PMID:2283661 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506 		JBrowse link
G Pttg1 pituitary tumor-transforming gene 1 increases expression ISO Mirex results in increased expression of PTTG1 mRNA CTD PMID:23153324 NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078 		JBrowse link
G Rfc4 replication factor C (activator 1) 4 increases expression ISO Mirex results in increased expression of RFC4 mRNA CTD PMID:23153324 NCBI chr16:22,932,698...22,946,480
Ensembl chr16:22,932,693...22,946,487 		JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases expression ISO Mirex results in increased expression of SERPINB2 mRNA CTD PMID:23153324 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208 		JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression ISO Mirex results in decreased expression of SLC10A1 mRNA CTD PMID:23153324 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479 		JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 decreases expression ISO Mirex results in decreased expression of SLC16A1 mRNA CTD PMID:23153324 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778 		JBrowse link
G Slc16a4 solute carrier family 16 (monocarboxylic acid transporters), member 4 decreases expression ISO Mirex results in decreased expression of SLC16A4 mRNA CTD PMID:23153324 NCBI chr 3:107,198,543...107,219,437
Ensembl chr 3:107,198,546...107,219,431 		JBrowse link
G Slc16a7 solute carrier family 16 (monocarboxylic acid transporters), member 7 decreases expression ISO Mirex results in decreased expression of SLC16A7 mRNA CTD PMID:23153324 NCBI chr10:125,055,139...125,225,455
Ensembl chr10:125,055,139...125,225,334 		JBrowse link
G Slc17a3 solute carrier family 17 (sodium phosphate), member 3 decreases expression ISO Mirex results in decreased expression of SLC17A3 mRNA CTD PMID:23153324 NCBI chr13:24,020,905...24,044,701
Ensembl chr13:24,023,417...24,044,699 		JBrowse link
G Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 decreases expression ISO Mirex results in decreased expression of SLC17A5 mRNA CTD PMID:23153324 NCBI chr 9:78,443,769...78,495,346
Ensembl chr 9:78,443,770...78,495,323 		JBrowse link
G Slc19a2 solute carrier family 19 (thiamine transporter), member 2 decreases expression ISO Mirex results in decreased expression of SLC19A2 mRNA CTD PMID:23153324 NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression ISO Mirex results in decreased expression of SLC2A2 mRNA CTD PMID:23153324 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc31a2 solute carrier family 31, member 2 decreases expression ISO Mirex results in decreased expression of SLC31A2 mRNA CTD PMID:23153324 NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648 		JBrowse link
G Slc34a2 solute carrier family 34 (sodium phosphate), member 2 decreases expression ISO Mirex results in decreased expression of SLC34A2 mRNA CTD PMID:23153324 NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 increases expression ISO Mirex results in increased expression of SLC38A1 mRNA CTD PMID:23153324 NCBI chr15:96,469,299...96,541,396
Ensembl chr15:96,469,299...96,540,794 		JBrowse link
G Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 increases expression ISO Mirex results in increased expression of SLC4A7 mRNA CTD PMID:23153324 NCBI chr14:7,669,819...7,766,808
Ensembl chr14:7,669,823...7,767,484 		JBrowse link
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 decreases expression ISO Mirex results in decreased expression of SLC5A6 mRNA CTD PMID:23153324 NCBI chr 5:31,193,380...31,206,268
Ensembl chr 5:31,193,380...31,206,268 		JBrowse link
G Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 decreases expression ISO Mirex results in decreased expression of SLC7A2 mRNA CTD PMID:23153324 NCBI chr 8:41,315,404...41,375,107
Ensembl chr 8:41,315,433...41,375,345 		JBrowse link
G Slc7a6 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 decreases expression ISO Mirex results in decreased expression of SLC7A6 mRNA CTD PMID:23153324 NCBI chr 8:106,894,718...106,925,346
Ensembl chr 8:106,895,489...106,925,338 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Mirex co-treated with Corticosterone] results in increased activity of TAT protein CTD PMID:2893471 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO Mirex results in increased expression of TRIP13 mRNA CTD PMID:23153324 NCBI chr13:74,060,577...74,085,855
Ensembl chr13:74,059,466...74,085,903 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22210
    role 22195
      chemical role 21439
        environmental contaminant 20022
          persistent organic pollutant 17615
            mirex 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 22210
    subatomic particle 22202
      composite particle 22202
        hadron 22202
          baryon 22202
            nucleon 22202
              atomic nucleus 22202
                atom 22202
                  main group element atom 22136
                    p-block element atom 22136
                      carbon group element atom 21936
                        carbon atom 21861
                          organic molecular entity 21861
                            heteroorganic entity 21517
                              organohalogen compound 20031
                                organochlorine compound 19675
                                  organochlorine pesticide 7516
                                    organochlorine insecticide 6759
                                      mirex 50
paths to the root