Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:octahydronaphthalenes
go back to main search page
Accession:CHEBI:138397 term browser browse the term
Definition:Any carbobycyclic compound that is an octahydronaphthalene or a compound obtained from an octahydronaphthalene by formal substitution of one or more hydrogens.


show annotations for term's descendants           Sort by:
(+)-artemisinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions		 ISO [artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of CEBPA mRNA
[[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol		 CTD PMID:23063590 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Dct dopachrome tautomerase decreases expression ISO artemisic acid results in decreased expression of DCT mRNA CTD PMID:23063590 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression		 ISO [[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA] which results in decreased chemical synthesis of Cholesterol; [artemisic acid results in decreased expression of HMGCR protein] which results in decreased chemical synthesis of Cholesterol
[artemisic acid results in decreased expression of CEBPA mRNA] which results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR mRNA; artemisic acid results in decreased expression of HMGCR protein		 CTD PMID:23063590 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO artemisic acid results in decreased expression of KIT mRNA CTD PMID:23063590 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kitlg KIT ligand decreases expression ISO artemisic acid results in decreased expression of KITLG mRNA CTD PMID:23063590 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Mif macrophage migration inhibitory factor decreases expression ISO artemisic acid results in decreased expression of MIF mRNA CTD PMID:23063590 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO artemisic acid results in decreased expression of MITF mRNA CTD PMID:23063590 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Tyr tyrosinase decreases expression ISO artemisic acid results in decreased expression of TYR mRNA CTD PMID:23063590 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO artemisic acid results in decreased expression of TYRP1 mRNA CTD PMID:23063590 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity ISO drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      molecular entity 19806
        polyatomic entity 19764
          molecule 19670
            cyclic compound 19486
              bicyclic compound 17279
                carbobicyclic compound 5872
                  octahydronaphthalenes 13
                    (+)-5-epi-aristolochene + 0
                    (+)-O-methylkolavelool 0
                    (+)-Tau-muurolol 0
                    (+)-artemisinic acid 9
                    (+)-artemisinic alcohol + 9
                    (+)-delta-cadinol 0
                    (+)-epicubenol 0
                    (+)-eremophilene 0
                    (+)-gamma-cadinene + 0
                    (+)-kolavelool + 0
                    (+)-kolavenyl diphosphate 0
                    (+)-subersic acid 0
                    (-)-4-epi-eremophilene + 0
                    (-)-5-epi-eremophilene 0
                    (-)-7-epi-alpha-selinene 0
                    (-)-Tau-muurolol 0
                    (-)-cubenol 0
                    (-)-delta-cadinol 0
                    (-)-epicubenol 0
                    (-)-eremophilene 0
                    (-)-gamma-cadinene + 0
                    (-)-kolavenyl diphosphate 0
                    (11R)-dihydroartemisinic aldehyde 0
                    (13E)-labda-7,13-dien-15-ol 0
                    (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene 0
                    1-epi-bicyclosesquiphellandrene 0
                    14-hydroxy-6,12-muuroloadien-15-oic acid 0
                    2beta-hydroxy-5-epi-aristolochene 0
                    5-epi-alpha-selinene 0
                    6-isopropenyl-4,4a-dimethyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol + 0
                    7-epi-alpha-eudesmol 0
                    8-epi-ilicicolin H 0
                    UCS1025 A 0
                    achilleol B 0
                    alpha,gamma-onoceradienediol 0
                    alpha-cadinol 0
                    alpha-eudesmol 0
                    alpha-seco-amyrin 0
                    alpha-selinene 0
                    amorpha-4,11-diene 0
                    aristolochene + 0
                    artemisinic aldehyde + 0
                    ballodiolic acid 0
                    ballotenic acid 0
                    beta-seco-amyrin 0
                    bicyclosesquiphellandrene 0
                    callicarpenal 0
                    capsidiol + 0
                    capsidiol 3-acetate 0
                    dihydroartemisinic acid 0
                    dihydromonacolin L + 0
                    dihydromonacolin L acid + 0
                    dihydrostemphyloxin I 0
                    drimendiol 0
                    drimenol + 4
                    drimenol diphosphate(3-) 0
                    drimenol phosphate(2-) 0
                    dysidine 0
                    elisabethatriene 0
                    equisetin 0
                    gamma-cadinene + 0
                    gamma-muurolene 0
                    hedychilactone D 0
                    ilicicolin H + 0
                    lamesticumin C 0
                    lamesticumin D 0
                    lobophytumin D 0
                    melemeleone B 0
                    mitchellene D 0
                    mitchellene E 0
                    oplodiol 0
                    sch 210971 0
                    sch 210972 + 0
                    sch 213766 0
                    scutebarbatine C 0
                    sibirene + 0
                    solanapyrone A + 0
                    solanapyrone B 0
                    solanapyrone C 0
                    solanapyrone D 0
                    solanapyrone E 0
                    stemphyloxin I + 0
                    talaroconvolutin A 0
                    tau-cadinol 0
                    terpentecin 0
                    terpentedienyl diphosphate 0
                    terpentetriene + 0
                    trichosetin + 0
                    valerianol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon group molecular entity 19705
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                carbocyclic compound 18559
                                  carbopolycyclic compound 17167
                                    carbobicyclic compound 5872
                                      octahydronaphthalenes 13
                                        (+)-5-epi-aristolochene + 0
                                        (+)-O-methylkolavelool 0
                                        (+)-Tau-muurolol 0
                                        (+)-artemisinic acid 9
                                        (+)-artemisinic alcohol + 9
                                        (+)-delta-cadinol 0
                                        (+)-epicubenol 0
                                        (+)-eremophilene 0
                                        (+)-gamma-cadinene + 0
                                        (+)-kolavelool + 0
                                        (+)-kolavenyl diphosphate 0
                                        (+)-subersic acid 0
                                        (-)-4-epi-eremophilene + 0
                                        (-)-5-epi-eremophilene 0
                                        (-)-7-epi-alpha-selinene 0
                                        (-)-Tau-muurolol 0
                                        (-)-cubenol 0
                                        (-)-delta-cadinol 0
                                        (-)-epicubenol 0
                                        (-)-eremophilene 0
                                        (-)-gamma-cadinene + 0
                                        (-)-kolavenyl diphosphate 0
                                        (11R)-dihydroartemisinic aldehyde 0
                                        (13E)-labda-7,13-dien-15-ol 0
                                        (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene 0
                                        1-epi-bicyclosesquiphellandrene 0
                                        14-hydroxy-6,12-muuroloadien-15-oic acid 0
                                        2beta-hydroxy-5-epi-aristolochene 0
                                        5-epi-alpha-selinene 0
                                        6-isopropenyl-4,4a-dimethyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol + 0
                                        7-epi-alpha-eudesmol 0
                                        8-epi-ilicicolin H 0
                                        UCS1025 A 0
                                        achilleol B 0
                                        alpha,gamma-onoceradienediol 0
                                        alpha-cadinol 0
                                        alpha-eudesmol 0
                                        alpha-seco-amyrin 0
                                        alpha-selinene 0
                                        amorpha-4,11-diene 0
                                        aristolochene + 0
                                        artemisinic aldehyde + 0
                                        ballodiolic acid 0
                                        ballotenic acid 0
                                        beta-seco-amyrin 0
                                        bicyclosesquiphellandrene 0
                                        callicarpenal 0
                                        capsidiol + 0
                                        capsidiol 3-acetate 0
                                        dihydroartemisinic acid 0
                                        dihydromonacolin L + 0
                                        dihydromonacolin L acid + 0
                                        dihydrostemphyloxin I 0
                                        drimendiol 0
                                        drimenol + 4
                                        drimenol diphosphate(3-) 0
                                        drimenol phosphate(2-) 0
                                        dysidine 0
                                        elisabethatriene 0
                                        equisetin 0
                                        gamma-cadinene + 0
                                        gamma-muurolene 0
                                        hedychilactone D 0
                                        ilicicolin H + 0
                                        lamesticumin C 0
                                        lamesticumin D 0
                                        lobophytumin D 0
                                        melemeleone B 0
                                        mitchellene D 0
                                        mitchellene E 0
                                        oplodiol 0
                                        sch 210971 0
                                        sch 210972 + 0
                                        sch 213766 0
                                        scutebarbatine C 0
                                        sibirene + 0
                                        solanapyrone A + 0
                                        solanapyrone B 0
                                        solanapyrone C 0
                                        solanapyrone D 0
                                        solanapyrone E 0
                                        stemphyloxin I + 0
                                        talaroconvolutin A 0
                                        tau-cadinol 0
                                        terpentecin 0
                                        terpentedienyl diphosphate 0
                                        terpentetriene + 0
                                        trichosetin + 0
                                        valerianol 0
paths to the root