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ONTOLOGY REPORT - ANNOTATIONS


Term:(+)-artemisinic alcohol
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Accession:CHEBI:64783 term browser browse the term
Definition:A monocarboxylic acid that is prop-2-en-1-ol acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). It is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua.
Synonyms:exact_synonym: 2-[(1R,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]prop-2-en-1-ol
 related_synonym: Formula=C15H24O;   InChI=1S/C15H24O/c1-10-4-6-13-11(2)5-7-14(12(3)9-16)15(13)8-10/h8,11,13-16H,3-7,9H2,1-2H3/t11-,13+,14+,15+/m1/s1;   InChIKey=CZSSHKCZSDDOAH-UNQGMJICSA-N;   SMILES=[H][C@@]12CCC(C)=C[C@]1([H])[C@@H](CC[C@H]2C)C(=C)CO;   amorpha-4,11-diene-12-ol
 xref: MetaCyc:CPD-7556;   PMID:16458889;   PMID:20723135;   PMID:2828054;   Patent:US2011162097;   Patent:WO2007048235;   Reaxys:8848568


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(+)-artemisinic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:6480464
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    chemical entity 19789
      molecular entity 19787
        polyatomic entity 19697
          molecule 19516
            cyclic compound 19285
              bicyclic compound 16595
                carbobicyclic compound 4559
                  (+)-artemisinic alcohol 9
                    (+)-artemisinic acid 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19483
                              organic cyclic compound 19246
                                carbocyclic compound 17628
                                  carbopolycyclic compound 14981
                                    carbobicyclic compound 4559
                                      octahydronaphthalenes 15
                                        (+)-artemisinic alcohol 9
                                          (+)-artemisinic acid 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.