H2ax Rat (+)-catechin multiple interactions ISO H2AX (Homo sapiens) 6480464 Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of H2AX protein] CTD PMID:21882252 H2ax Rat (+)-dexrazoxane multiple interactions ISO H2ax (Mus musculus) 6480464 Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein] CTD PMID:37690746 H2ax Rat (-)-ephedrine multiple interactions EXP 6480464 [Caffeine co-treated with Ephedrine] results in increased phosphorylation of H2AX protein CTD PMID:15537744 H2ax Rat (-)-epigallocatechin 3-gallate increases phosphorylation ISO H2ax (Mus musculus) 6480464 epigallocatechin gallate results in increased phosphorylation of H2AX protein CTD PMID:25528115 H2ax Rat (-)-epigallocatechin 3-gallate multiple interactions ISO H2ax (Mus musculus) 6480464 epigallocatechin gallate inhibits the reaction [epigallocatechin gallate results in increased phosphorylation of H2AX protein] CTD PMID:25528115 H2ax Rat (-)-epigallocatechin 3-gallate increases expression ISO H2ax (Mus musculus) 6480464 epigallocatechin gallate results in increased expression of H2AX protein CTD PMID:25585349|PMID:29175576 H2ax Rat (1->4)-beta-D-glucan multiple interactions ISO H2ax (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of H2AX mRNA CTD PMID:36331819 H2ax Rat (S)-nicotine multiple interactions ISO H2AX (Homo sapiens) 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein modified form] CTD PMID:23907605 H2ax Rat 1,10-phenanthroline multiple interactions ISO H2AX (Homo sapiens) 6480464 [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased expression of H2AX more ... CTD PMID:22659117 H2ax Rat 1,2-dimethylhydrazine increases expression EXP 6480464 1,2-Dimethylhydrazine results in increased expression of H2AX protein CTD PMID:32387197 H2ax Rat 1,2-dimethylhydrazine increases expression ISO H2ax (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of H2AX protein CTD PMID:38563870 H2ax Rat 1,2-dimethylhydrazine multiple interactions ISO H2ax (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of H2AX mRNA CTD PMID:22206623 H2ax Rat 1,3-benzothiazole-2-thiol increases expression ISO H2AX (Homo sapiens) 6480464 captax results in increased expression of H2AX protein CTD PMID:35279910 H2ax Rat 1,3-benzothiazole-2-thiol multiple interactions ISO H2AX (Homo sapiens) 6480464 1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the more ... CTD PMID:35279910 H2ax Rat 1,3-dinitrobenzene decreases expression EXP 6480464 3-dinitrobenzene results in decreased expression of H2AX mRNA CTD PMID:21983209 H2ax Rat 1,4-benzoquinone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 quinone results in increased phosphorylation of H2AX protein CTD PMID:18835433 H2ax Rat 1,4-benzoquinone multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [quinone analog results in increased expression of H2AX protein modified form]; more ... CTD PMID:33961949 H2ax Rat 1,4-benzoquinone increases expression ISO H2ax (Mus musculus) 6480464 quinone analog results in increased expression of H2AX protein modified form CTD PMID:33961949 H2ax Rat 1,4-benzoquinone increases phosphorylation ISO H2ax (Mus musculus) 6480464 quinone results in increased phosphorylation of H2AX protein CTD PMID:31340051 H2ax Rat 1,4-dioxane increases expression ISO H2ax (Mus musculus) 6480464 1,4-dioxane results in increased expression of H2AX protein CTD PMID:33693819 H2ax Rat 1,4-dioxane increases expression EXP 6480464 1,4-dioxane results in increased expression of H2AX protein CTD PMID:37258237 H2ax Rat 1-aminobenzotriazole multiple interactions ISO H2AX (Homo sapiens) 6480464 1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 1-aminobenzotriazole inhibits the more ... CTD PMID:28300663|PMID:29722447|PMID:35279910 H2ax Rat 1-fluoro-2,4-dinitrobenzene increases expression ISO H2AX (Homo sapiens) 6480464 Dinitrofluorobenzene results in increased expression of H2AX mRNA CTD PMID:23999411 H2ax Rat 1-naphthyl isothiocyanate affects expression EXP 6480464 1-Naphthylisothiocyanate affects the expression of H2AX protein CTD PMID:26011634 H2ax Rat 17alpha-ethynylestradiol increases expression ISO H2ax (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of H2AX mRNA CTD PMID:12072388 H2ax Rat 17beta-estradiol increases expression ISO H2AX (Homo sapiens) 6480464 Estradiol results in increased expression of H2AX mRNA; Estradiol results in increased expression of H2AX more ... CTD PMID:16462019|PMID:16474171|PMID:19167446|PMID:25933419|PMID:31939680 H2ax Rat 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of H2AX mRNA CTD PMID:32145629 H2ax Rat 17beta-estradiol increases expression ISO H2ax (Mus musculus) 6480464 Estradiol results in increased expression of H2AX protein modified form CTD PMID:31939680 H2ax Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of H2AX protein CTD PMID:23788033 H2ax Rat 17beta-estradiol multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [Estradiol results in increased expression of H2AX protein] CTD PMID:23788033 H2ax Rat 17beta-estradiol multiple interactions ISO H2AX (Homo sapiens) 6480464 Estradiol promotes the reaction [PCB 180 metabolite results in increased phosphorylation of H2AX protein]; Fulvestrant more ... CTD PMID:26148434|PMID:31939680 H2ax Rat 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO H2AX (Homo sapiens) 6480464 [ATM mutant form inhibits the reaction [Metribolone results in increased expression of H2AX protein]] which more ... CTD PMID:21134073|PMID:23272087 H2ax Rat 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO H2AX (Homo sapiens) 6480464 Metribolone results in increased expression of H2AX protein CTD PMID:23272087 H2ax Rat 1H-pyrazole increases expression ISO H2ax (Mus musculus) 6480464 pyrazole results in increased expression of H2AX mRNA CTD PMID:17945193 H2ax Rat 2'-Hydroxy-2,3,5'-trimethoxychalcone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 2-hydroxy-3',5,5'-trimethoxychalcone results in increased phosphorylation of H2AX protein CTD PMID:30408460 H2ax Rat 2'-Hydroxy-2,3,5'-trimethoxychalcone multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased phosphorylation of H2AX protein] CTD PMID:30408460 H2ax Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO H2ax (Mus musculus) 6480464 2,2',4,4'-tetrabromodiphenyl ether affects the expression of H2AX mRNA CTD PMID:30294300 H2ax Rat 2,2'-bipyridine multiple interactions ISO H2AX (Homo sapiens) 6480464 [Copper binds to phthalic acid binds to 2,2'-Dipyridyl] which results in increased expression of H2AX more ... CTD PMID:22659117 H2ax Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO H2ax (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in increased expression of H2AX mRNA CTD PMID:31388691 H2ax Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO H2ax (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of H2AX protein CTD PMID:21846477|PMID:33823233 H2ax Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of H2AX mRNA CTD PMID:33387578 H2ax Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO H2ax (Mus musculus) 6480464 NFE2L2 gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of H2AX protein]; more ... CTD PMID:21846477 H2ax Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO H2ax (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of H2AX mRNA CTD PMID:21570461 H2ax Rat 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO H2AX (Homo sapiens) 6480464 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of H2AX mRNA CTD PMID:19031421 H2ax Rat 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of H2AX mRNA CTD PMID:21346803 H2ax Rat 2,4-diaminotoluene decreases expression ISO H2ax (Mus musculus) 6480464 2,4-diaminotoluene results in decreased expression of H2AX mRNA CTD PMID:20713471 H2ax Rat 2,4-diaminotoluene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 2,4-diaminotoluene results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 2,4-dibromophenol multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; more ... CTD PMID:33961949 H2ax Rat 2,4-dibromophenol increases expression ISO H2ax (Mus musculus) 6480464 2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form CTD PMID:33961949 H2ax Rat 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of H2AX protein CTD PMID:26338220 H2ax Rat 2-acetamidofluorene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 2-Acetylaminofluorene results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 2-Amino-3-methyl-9H-pyrido[2,3-b]indole increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat 2-Amino-9H-pyrido[2,3-b]indole increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-9H-pyrido(2,3-b)indole results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat 2-deoxy-D-glucose decreases expression ISO H2AX (Homo sapiens) 6480464 Deoxyglucose results in decreased expression of H2AX protein CTD PMID:23363784 H2ax Rat 2-hydroxyethyl methacrylate increases expression ISO H2ax (Mus musculus) 6480464 hydroxyethyl methacrylate results in increased expression of H2AX protein CTD PMID:37778984 H2ax Rat 2-methoxy-17beta-estradiol increases expression ISO H2AX (Homo sapiens) 6480464 2-Methoxyestradiol results in increased expression of H2AX protein modified form CTD PMID:23967052 H2ax Rat 2-nitroanisole increases expression EXP 6480464 2-nitroanisole results in increased expression of H2AX protein CTD PMID:26338220 H2ax Rat 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat 2-nitropropane increases phosphorylation EXP 6480464 2-nitropropane results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat 2-palmitoylglycerol increases expression ISO H2AX (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of H2AX mRNA CTD PMID:37199045 H2ax Rat 2-phenylethylamine multiple interactions ISO H2AX (Homo sapiens) 6480464 [NAT2 protein results in increased susceptibility to phenethylamine] which results in increased expression of H2AX more ... CTD PMID:36138126 H2ax Rat 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of H2AX protein] CTD PMID:28583816 H2ax Rat 2-tert-butylhydroquinone multiple interactions ISO H2AX (Homo sapiens) 6480464 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein] CTD PMID:35123993 H2ax Rat 2-tert-butylhydroquinone increases expression ISO H2AX (Homo sapiens) 6480464 2-tert-butylhydroquinone results in increased expression of H2AX protein CTD PMID:35123993 H2ax Rat 3,3',4,4',5-pentachlorobiphenyl increases expression ISO H2AX (Homo sapiens) 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2AX protein CTD PMID:31733235 H2ax Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO H2AX (Homo sapiens) 6480464 2,4,3',5'-tetramethoxystilbene inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2AX protein] CTD PMID:31733235 H2ax Rat 3,3',4,4'-tetrachlorobiphenyl increases expression ISO H2AX (Homo sapiens) 6480464 3,4,3',4'-tetrachlorobiphenyl results in increased expression of H2AX protein CTD PMID:31733235 H2ax Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO H2AX (Homo sapiens) 6480464 2,4,3',5'-tetramethoxystilbene inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of H2AX protein] CTD PMID:31733235 H2ax Rat 3,3',5-triiodo-L-thyronine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Triiodothyronine analog results in increased phosphorylation of H2AX protein CTD PMID:22383522 H2ax Rat 3,3',5-triiodo-L-thyronine multiple interactions ISO H2AX (Homo sapiens) 6480464 Triiodothyronine analog promotes the reaction [Cisplatin results in increased expression of H2AX protein] CTD PMID:22383522 H2ax Rat 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases expression ISO H2AX (Homo sapiens) 6480464 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat 3,4-methylenedioxymethamphetamine multiple interactions ISO H2AX (Homo sapiens) 6480464 [NAT2 protein results in increased susceptibility to N-Methyl-3,4-methylenedioxyamphetamine] which results in increased expression of H2AX more ... CTD PMID:36138126 H2ax Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole increases expression ISO H2AX (Homo sapiens) 6480464 3-amino-1-methyl-5H-pyrido(4,3-b)indole results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-3-methylimidazo(4,5-f)quinoline results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 2-amino-3-methylimidazo(4,5-f)quinoline results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 3-methyladenine multiple interactions ISO H2AX (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Aflatoxin B1 results in increased expression of H2AX protein] CTD PMID:34396909 H2ax Rat 3-nitropropanoic acid increases expression ISO H2ax (Mus musculus) 6480464 3-nitropropionic acid results in increased expression of H2AX protein CTD PMID:39832703 H2ax Rat 4,4'-sulfonyldiphenol increases expression ISO H2ax (Mus musculus) 6480464 bisphenol S results in increased expression of H2AX mRNA CTD PMID:39298647 H2ax Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 H2ax Rat 4,4'-sulfonyldiphenol multiple interactions ISO H2AX (Homo sapiens) 6480464 [bisphenol S co-treated with cylindrospermopsin] results in increased expression of H2AX protein CTD PMID:32244372 H2ax Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the more ... CTD PMID:21882252|PMID:26231820|PMID:34784199|PMID:35435490 H2ax Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO H2AX (Homo sapiens) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX more ... CTD PMID:34784199|PMID:35435490 H2ax Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein CTD PMID:26231820 H2ax Rat 4-Aminophenyl ether increases expression ISO H2AX (Homo sapiens) 6480464 di-(4-aminophenyl)ether results in increased expression of H2AX protein CTD PMID:38906436 H2ax Rat 4-chloroaniline increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-chloroaniline results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 4-hydroxynon-2-enal multiple interactions ISO H2ax (Mus musculus) 6480464 POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLK protein more ... CTD PMID:22331492 H2ax Rat 4-hydroxynon-2-enal increases expression ISO H2AX (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of H2AX protein CTD PMID:34503147 H2ax Rat 4-hydroxynon-2-enal multiple interactions ISO H2AX (Homo sapiens) 6480464 [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with more ... CTD PMID:34503147 H2ax Rat 4-hydroxynon-2-enal increases phosphorylation ISO H2ax (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein CTD PMID:22331492 H2ax Rat 4-methoxy-TEMPO multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; pyrazolanthrone inhibits the more ... CTD PMID:28993908 H2ax Rat 4-methoxy-TEMPO increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein CTD PMID:28993908 H2ax Rat 4-Nerolidylcatechol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-nerolidylcatechol results in increased phosphorylation of H2AX protein CTD PMID:22372875 H2ax Rat 4-nitroquinoline N-oxide increases expression ISO H2AX (Homo sapiens) 6480464 4-Nitroquinoline-1-oxide results in increased expression of H2AX protein CTD PMID:32087850 H2ax Rat 4-nitroquinoline N-oxide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-Nitroquinoline-1-oxide results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 4-nonylphenol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-nonylphenol results in increased phosphorylation of H2AX protein CTD PMID:32466334 H2ax Rat 4-tert-Octylphenol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of H2AX protein CTD PMID:32466334 H2ax Rat 4-vinylcyclohexene dioxide increases expression ISO H2AX (Homo sapiens) 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of H2AX protein CTD PMID:37182589 H2ax Rat 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid multiple interactions ISO H2AX (Homo sapiens) 6480464 pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased more ... CTD PMID:32941855 H2ax Rat 5-aza-2'-deoxycytidine multiple interactions ISO H2AX (Homo sapiens) 6480464 ATM protein affects the reaction [Decitabine results in increased expression of H2AX protein]; DNMT1 protein more ... CTD PMID:17991895|PMID:19732952 H2ax Rat 5-aza-2'-deoxycytidine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Decitabine results in increased phosphorylation of H2AX protein CTD PMID:19215824|PMID:19732952 H2ax Rat 5-aza-2'-deoxycytidine increases expression ISO H2AX (Homo sapiens) 6480464 Decitabine results in increased expression of H2AX protein CTD PMID:17991895|PMID:18223691 H2ax Rat 5-aza-2'-deoxycytidine affects localization ISO H2AX (Homo sapiens) 6480464 Decitabine affects the localization of H2AX protein CTD PMID:17991895 H2ax Rat 5-azacytidine increases expression ISO H2AX (Homo sapiens) 6480464 Azacitidine results in increased expression of H2AX protein CTD PMID:17991895 H2ax Rat 5-azacytidine multiple interactions EXP 6480464 Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein] CTD PMID:25015661 H2ax Rat 5-chloro-7-iodoquinolin-8-ol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Clioquinol results in increased phosphorylation of H2AX protein CTD PMID:22627294 H2ax Rat 5-fluorouracil multiple interactions ISO H2AX (Homo sapiens) 6480464 [Fluorouracil co-treated with olaparib] results in increased phosphorylation of H2AX protein; [S100A11 mutant form results more ... CTD PMID:15016801|PMID:25940438|PMID:26544897 H2ax Rat 5-fluorouracil increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Fluorouracil results in increased phosphorylation of H2AX protein CTD PMID:26544897|PMID:34510228 H2ax Rat 5-fluorouracil affects expression ISO H2AX (Homo sapiens) 6480464 Fluorouracil affects the expression of H2AX mRNA CTD PMID:16584549 H2ax Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of H2AX mRNA CTD PMID:24780913 H2ax Rat 680C91 decreases expression ISO H2AX (Homo sapiens) 6480464 TDO inhibitor LM10 results in decreased expression of H2AX protein modified form CTD PMID:26651356 H2ax Rat 7,12-dimethyltetraphene increases expression EXP 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AX protein CTD PMID:23969067 H2ax Rat 7,12-dimethyltetraphene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat 7,12-dimethyltetraphene increases expression ISO H2ax (Mus musculus) 6480464 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of H2AX protein modified form; 9,10-Dimethyl-1,2-benzanthracene results in increased more ... CTD PMID:25448685|PMID:32553695 H2ax Rat 7,12-dimethyltetraphene multiple interactions ISO H2ax (Mus musculus) 6480464 A gene mutant form affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of H2AX protein] CTD PMID:25448685 H2ax Rat 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO H2ax (Mus musculus) 6480464 CASP1 gene mutant form inhibits the reaction [Uric Acid results in increased phosphorylation of H2AX more ... CTD PMID:23619996 H2ax Rat 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases phosphorylation ISO H2ax (Mus musculus) 6480464 Uric Acid results in increased phosphorylation of H2AX protein CTD PMID:23619996 H2ax Rat 9-aminoacridine multiple interactions ISO H2AX (Homo sapiens) 6480464 [Aminacrine results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in increased more ... CTD PMID:26928355 H2ax Rat 9-aminoacridine decreases phosphorylation ISO H2AX (Homo sapiens) 6480464 Aminacrine results in decreased phosphorylation of H2AX protein CTD PMID:26928355 H2ax Rat [6]-Shogaol multiple interactions ISO H2AX (Homo sapiens) 6480464 shogaol analog inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein] CTD PMID:23899529 H2ax Rat ABT-737 multiple interactions ISO H2AX (Homo sapiens) 6480464 [ABT-737 co-treated with hydroquinone] results in increased expression of H2AX protein CTD PMID:28843007 H2ax Rat acetylsalicylic acid decreases expression ISO H2AX (Homo sapiens) 6480464 Aspirin results in decreased expression of H2AX protein CTD PMID:23363784 H2ax Rat acrolein increases expression ISO H2AX (Homo sapiens) 6480464 Acrolein results in increased expression of H2AX protein CTD PMID:34958888 H2ax Rat acrylamide increases expression ISO H2ax (Mus musculus) 6480464 Acrylamide results in increased expression of H2AX protein CTD PMID:36599426|PMID:36997053 H2ax Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of H2AX protein CTD PMID:37987225 H2ax Rat acrylamide multiple interactions EXP 6480464 Selenium inhibits the reaction [Acrylamide results in increased expression of H2AX protein] CTD PMID:37987225 H2ax Rat acrylonitrile increases expression ISO H2ax (Mus musculus) 6480464 Acrylonitrile results in increased expression of H2AX protein CTD PMID:35429547 H2ax Rat actinomycin D increases expression ISO H2AX (Homo sapiens) 6480464 Dactinomycin results in increased expression of H2AX protein CTD PMID:31226288 H2ax Rat adenosine multiple interactions ISO H2AX (Homo sapiens) 6480464 Adenosine promotes the reaction [Cesium-137 results in increased expression of and affects the localization of more ... CTD PMID:32941855 H2ax Rat adenosine 5'-monophosphate multiple interactions ISO H2AX (Homo sapiens) 6480464 Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat ADP multiple interactions ISO H2AX (Homo sapiens) 6480464 Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat aflatoxin B1 multiple interactions ISO H2AX (Homo sapiens) 6480464 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Aflatoxin B1 results in increased expression of H2AX protein]; 3-methyladenine inhibits more ... CTD PMID:28882572|PMID:31103741|PMID:33984424|PMID:34396909|PMID:36442682|PMID:38382706 H2ax Rat aflatoxin B1 increases expression ISO H2ax (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of H2AX protein CTD PMID:34396909 H2ax Rat aflatoxin B1 increases expression ISO H2AX (Homo sapiens) 6480464 Aflatoxin B1 analog results in increased expression of H2AX protein; Aflatoxin B1 results in increased more ... CTD PMID:31154085|PMID:32106047|PMID:33164849|PMID:33984424|PMID:34396909|PMID:35690182|PMID:36442682 H2ax Rat aflatoxin B1 increases methylation ISO H2AX (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of H2AX polyA tail CTD PMID:30157460 H2ax Rat aflatoxin B1 increases phosphorylation ISO H2ax (Mus musculus) 6480464 Aflatoxin B1 results in increased phosphorylation of H2AX protein CTD PMID:19770486 H2ax Rat aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat aflatoxin B1 increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Aflatoxin B1 results in increased phosphorylation of H2AX protein CTD PMID:28882572|PMID:34510228 H2ax Rat Aflatoxin G1 increases expression ISO H2AX (Homo sapiens) 6480464 aflatoxin G1 results in increased expression of H2AX protein modified form CTD PMID:23907605 H2ax Rat Aflatoxin G1 increases phosphorylation ISO H2AX (Homo sapiens) 6480464 aflatoxin G1 results in increased phosphorylation of H2AX protein CTD PMID:36997055 H2ax Rat Aflatoxin G1 multiple interactions ISO H2ax (Mus musculus) 6480464 aflatoxin G1 results in increased expression of and results in increased localization of H2AX protein; more ... CTD PMID:36997055 H2ax Rat Aflatoxin G1 multiple interactions ISO H2AX (Homo sapiens) 6480464 CYP2E1 promotes the reaction [aflatoxin G1 results in increased expression of H2AX protein]; Methoxsalen inhibits more ... CTD PMID:23907605|PMID:36997055 H2ax Rat aldehydo-D-glucose increases expression ISO H2ax (Mus musculus) 6480464 Glucose results in increased expression of H2AX protein CTD PMID:31672611 H2ax Rat aldehydo-D-glucose multiple interactions ISO H2ax (Mus musculus) 6480464 Glucose promotes the reaction [Bupivacaine results in increased expression of H2AX protein] CTD PMID:31672611 H2ax Rat alizarin multiple interactions ISO H2AX (Homo sapiens) 6480464 alizarin inhibits the reaction [Benzo(a)pyrene results in increased expression of H2AX protein] CTD PMID:37515497 H2ax Rat all-trans-retinoic acid decreases expression ISO H2AX (Homo sapiens) 6480464 Tretinoin results in decreased expression of H2AX mRNA CTD PMID:16249480|PMID:33167477 H2ax Rat all-trans-retinoic acid increases expression ISO H2ax (Mus musculus) 6480464 Tretinoin results in increased expression of H2AX protein CTD PMID:33823233 H2ax Rat all-trans-retinoic acid multiple interactions ISO H2AX (Homo sapiens) 6480464 [alpha-pyrrolidinononanophenone analog co-treated with Tretinoin] results in increased expression of H2AX protein CTD PMID:38040126 H2ax Rat alternariol increases expression ISO H2AX (Homo sapiens) 6480464 alternariol results in increased expression of H2AX protein modified form CTD PMID:26341179 H2ax Rat aluminium atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [erionite results in increased abundance of Aluminum] which results in increased phosphorylation of H2AX protein CTD PMID:38605572 H2ax Rat aluminium(0) multiple interactions ISO H2AX (Homo sapiens) 6480464 [erionite results in increased abundance of Aluminum] which results in increased phosphorylation of H2AX protein CTD PMID:38605572 H2ax Rat alvocidib affects expression ISO H2AX (Homo sapiens) 6480464 alvocidib affects the expression of H2AX protein CTD PMID:15078984 H2ax Rat alvocidib multiple interactions ISO H2AX (Homo sapiens) 6480464 alvocidib inhibits the reaction [Benzo(a)pyrene results in increased expression of H2AX protein] CTD PMID:37515497 H2ax Rat amsacrine multiple interactions ISO H2AX (Homo sapiens) 6480464 ATM protein promotes the reaction [Amsacrine results in increased phosphorylation of H2AX protein] CTD PMID:37451322 H2ax Rat amsacrine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Amsacrine results in increased phosphorylation of H2AX protein CTD PMID:37451322 H2ax Rat anthocyanin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Anthocyanins results in increased phosphorylation of H2AX protein CTD PMID:27444805 H2ax Rat anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO H2AX (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; pyrazolanthrone inhibits the more ... CTD PMID:25619392|PMID:28993908 H2ax Rat aphidicolin multiple interactions ISO H2AX (Homo sapiens) 6480464 Aphidicolin inhibits the reaction [Docetaxel results in increased expression of H2AX protein] CTD PMID:20878124 H2ax Rat aristolochic acid A multiple interactions ISO H2ax (Mus musculus) 6480464 TRP53 protein affects the reaction [aristolochic acid I results in increased expression of H2AX protein] CTD PMID:31602497 H2ax Rat aristolochic acid A increases expression ISO H2AX (Homo sapiens) 6480464 aristolochic acid I results in increased expression of H2AX mRNA CTD PMID:33212167 H2ax Rat aristolochic acid A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [aristolochic acid I results in increased expression of H2AX protein] CTD PMID:36863539 H2ax Rat aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of H2AX protein CTD PMID:36863539 H2ax Rat aristolochic acid A increases expression ISO H2ax (Mus musculus) 6480464 aristolochic acid I results in increased expression of H2AX protein CTD PMID:31602497 H2ax Rat arsane increases expression ISO H2AX (Homo sapiens) 6480464 Arsenic results in increased expression of H2AX mRNA; Arsenic results in increased expression of H2AX more ... CTD PMID:29161537|PMID:31822296|PMID:34998823|PMID:35821281|PMID:38723480 H2ax Rat arsane decreases expression ISO H2ax (Mus musculus) 6480464 Arsenic results in decreased expression of H2AX protein CTD PMID:37888683 H2ax Rat arsane multiple interactions ISO H2ax (Mus musculus) 6480464 GW 4064 affects the reaction [Arsenic results in decreased expression of H2AX protein] CTD PMID:37888683 H2ax Rat arsane increases expression ISO H2ax (Mus musculus) 6480464 Arsenic results in increased expression of H2AX protein CTD PMID:34998823 H2ax Rat arsane multiple interactions ISO H2AX (Homo sapiens) 6480464 [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of H2AX more ... CTD PMID:31822296|PMID:34998823|PMID:35809665|PMID:35821281|PMID:38723480 H2ax Rat arsane multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in more ... CTD PMID:31542844 H2ax Rat arsenic atom increases expression ISO H2AX (Homo sapiens) 6480464 Arsenic results in increased expression of H2AX mRNA; Arsenic results in increased expression of H2AX more ... CTD PMID:29161537|PMID:31822296|PMID:34998823|PMID:35821281|PMID:38723480 H2ax Rat arsenic atom multiple interactions ISO H2ax (Mus musculus) 6480464 GW 4064 affects the reaction [Arsenic results in decreased expression of H2AX protein] CTD PMID:37888683 H2ax Rat arsenic atom decreases expression ISO H2ax (Mus musculus) 6480464 Arsenic results in decreased expression of H2AX protein CTD PMID:37888683 H2ax Rat arsenic atom increases expression ISO H2ax (Mus musculus) 6480464 Arsenic results in increased expression of H2AX protein CTD PMID:34998823 H2ax Rat arsenic atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of H2AX more ... CTD PMID:31822296|PMID:34998823|PMID:35809665|PMID:35821281|PMID:38723480 H2ax Rat arsenic atom multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in more ... CTD PMID:31542844 H2ax Rat arsenic trichloride multiple interactions ISO H2AX (Homo sapiens) 6480464 [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of H2AX more ... CTD PMID:35809665 H2ax Rat arsenite(3-) multiple interactions ISO H2AX (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to H2AX mRNA] CTD PMID:32406909 H2ax Rat arsenite(3-) increases expression ISO H2ax (Mus musculus) 6480464 arsenite results in increased expression of H2AX protein CTD PMID:38563870 H2ax Rat arsenous acid multiple interactions ISO H2AX (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with ruxolitinib] results in increased phosphorylation of H2AX protein; [Arsenic Trioxide co-treated more ... CTD PMID:18636201|PMID:23861973|PMID:28318385|PMID:30012499 H2ax Rat arsenous acid increases expression ISO H2AX (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of H2AX protein; Arsenic Trioxide results in increased expression more ... CTD PMID:28265077|PMID:28318385|PMID:31597699 H2ax Rat arsenous acid multiple interactions EXP 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of H2AX protein] CTD PMID:23337567 H2ax Rat arsenous acid increases expression ISO H2ax (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of H2AX protein modified form CTD PMID:28265077 H2ax Rat arsenous acid increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of H2AX protein CTD PMID:16891316|PMID:23861973 H2ax Rat arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of H2AX protein CTD PMID:23337567 H2ax Rat artesunate increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Artesunate results in increased phosphorylation of H2AX protein CTD PMID:31664825 H2ax Rat artesunate multiple interactions ISO H2AX (Homo sapiens) 6480464 APOBEC3C protein promotes the reaction [Artesunate results in increased phosphorylation of H2AX protein] CTD PMID:31664825 H2ax Rat ATP multiple interactions ISO H2AX (Homo sapiens) 6480464 Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat atrazine affects expression ISO H2ax (Mus musculus) 6480464 Atrazine affects the expression of H2AX protein modified form CTD PMID:26518232 H2ax Rat auramine O increases phosphorylation EXP 6480464 Benzophenoneidum results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat azathioprine decreases expression ISO H2AX (Homo sapiens) 6480464 Azathioprine results in decreased expression of H2AX mRNA CTD PMID:22623647 H2ax Rat Azoxymethane increases expression ISO H2ax (Mus musculus) 6480464 Azoxymethane results in increased expression of H2AX protein CTD PMID:38563870 H2ax Rat bafilomycin A1 multiple interactions ISO H2AX (Homo sapiens) 6480464 bafilomycin A1 promotes the reaction [sodium arsenite results in increased expression of H2AX protein] CTD PMID:38678786 H2ax Rat Benz[c]acridine increases expression ISO H2AX (Homo sapiens) 6480464 benz(c)acridine metabolite results in increased expression of H2AX protein CTD PMID:31051210 H2ax Rat benzene increases expression ISO H2ax (Mus musculus) 6480464 Benzene results in increased expression of H2AX mRNA CTD PMID:15120971|PMID:15122651 H2ax Rat benzene increases phosphorylation ISO H2ax (Mus musculus) 6480464 Benzene results in increased phosphorylation of H2AX protein CTD PMID:35963423 H2ax Rat benzidine increases phosphorylation EXP 6480464 benzidine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat benzidine multiple interactions ISO H2AX (Homo sapiens) 6480464 [NAT1 polymorphism affects the susceptibility to benzidine] which affects the expression of H2AX CTD PMID:37097310 H2ax Rat benzo[a]pyrene increases expression ISO H2AX (Homo sapiens) 6480464 Benzo(a)pyrene metabolite results in increased expression of H2AX protein; Benzo(a)pyrene results in increased expression of more ... CTD PMID:21873372|PMID:26657896|PMID:31051210|PMID:31733235|PMID:32087850|PMID:33249052|PMID:35690182|PMID:37390851|PMID:37515497 H2ax Rat benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of H2AX protein modified form CTD PMID:34283317 H2ax Rat benzo[a]pyrene increases phosphorylation ISO H2ax (Mus musculus) 6480464 Benzo(a)pyrene results in increased phosphorylation of H2AX protein CTD PMID:19770486|PMID:33393179 H2ax Rat benzo[a]pyrene increases methylation ISO H2AX (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of H2AX promoter CTD PMID:27901495 H2ax Rat benzo[a]pyrene increases expression ISO H2ax (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of H2AX protein modified form CTD PMID:32553695 H2ax Rat benzo[a]pyrene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Benzo(a)pyrene results in increased phosphorylation of H2AX protein CTD PMID:20888899|PMID:22389207|PMID:26148434|PMID:28882572|PMID:29126329|PMID:33393179|PMID:34510228 H2ax Rat benzo[a]pyrene multiple interactions ISO H2ax (Mus musculus) 6480464 pinocembrin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of H2AX protein] CTD PMID:33393179 H2ax Rat benzo[a]pyrene multiple interactions ISO H2AX (Homo sapiens) 6480464 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Benzo(a)pyrene results in increased expression of H2AX protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide more ... CTD PMID:20888899|PMID:21882252|PMID:26148434|PMID:28882572|PMID:31733235|PMID:33249052|PMID:33393179|PMID:36399157|PMID:36982514|PMID:37515497|PMID:38382706 H2ax Rat benzo[a]pyrene diol epoxide I increases expression ISO H2AX (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of H2AX mRNA CTD PMID:19150397 H2ax Rat benzo[a]pyrene diol epoxide I increases phosphorylation ISO H2ax (Mus musculus) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of H2AX protein CTD PMID:22331492 H2ax Rat benzo[a]pyrene diol epoxide I multiple interactions ISO H2ax (Mus musculus) 6480464 POLH protein affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of H2AX protein]; REV1 more ... CTD PMID:22331492 H2ax Rat benzo[a]pyrene diol epoxide I affects phosphorylation ISO H2AX (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the phosphorylation of H2AX protein CTD PMID:18848825 H2ax Rat benzo[a]pyrene diol epoxide I decreases expression ISO H2AX (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of H2AX mRNA CTD PMID:20382639 H2ax Rat benzo[a]pyrene diol epoxide I multiple interactions ISO H2AX (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide] results in increased phosphorylation of H2AX protein CTD PMID:18848825 H2ax Rat benzo[e]pyrene increases methylation ISO H2AX (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of H2AX polyA tail CTD PMID:30157460 H2ax Rat Benzo[ghi]perylene multiple interactions ISO H2AX (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of H2AX protein] CTD PMID:35182551 H2ax Rat Benzo[ghi]perylene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 1,12-benzoperylene results in increased phosphorylation of H2AX protein CTD PMID:37150498 H2ax Rat Benzo[ghi]perylene increases expression ISO H2AX (Homo sapiens) 6480464 1,12-benzoperylene results in increased expression of H2AX protein CTD PMID:31518672|PMID:35182551 H2ax Rat berberine increases expression ISO H2AX (Homo sapiens) 6480464 Berberine results in increased expression of H2AX protein modified form CTD PMID:23747414 H2ax Rat berberine decreases expression ISO H2AX (Homo sapiens) 6480464 Berberine results in decreased expression of H2AX mRNA; Berberine results in decreased expression of H2AX more ... CTD PMID:23363784|PMID:27311644 H2ax Rat berberine multiple interactions ISO H2AX (Homo sapiens) 6480464 TOP2A protein affects the reaction [Berberine results in increased expression of H2AX protein modified form] CTD PMID:23747414 H2ax Rat beta-hexachlorocyclohexane increases phosphorylation ISO H2AX (Homo sapiens) 6480464 beta-hexachlorocyclohexane results in increased phosphorylation of H2AX protein CTD PMID:33207735 H2ax Rat betaxolol increases expression ISO H2AX (Homo sapiens) 6480464 Betaxolol results in increased expression of H2AX protein CTD PMID:38325520 H2ax Rat biphenyl-4-amine increases expression ISO H2AX (Homo sapiens) 6480464 4-biphenylamine results in increased expression of H2AX protein CTD PMID:32433928|PMID:32905825|PMID:33847444 H2ax Rat biphenyl-4-amine multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of H2AX protein]; Propolis inhibits the more ... CTD PMID:32433928|PMID:32905825|PMID:33847444 H2ax Rat bis(2-chloroethyl) sulfide increases expression ISO H2AX (Homo sapiens) 6480464 Mustard Gas results in increased expression of H2AX protein modified form CTD PMID:25102026 H2ax Rat bis(2-chloroethyl) sulfide decreases expression ISO H2AX (Homo sapiens) 6480464 Mustard Gas results in decreased expression of H2AX mRNA CTD PMID:33491125 H2ax Rat bis(2-chloroethyl) sulfide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Mustard Gas results in increased phosphorylation of H2AX protein CTD PMID:20435105|PMID:25448276 H2ax Rat bis(2-chloroethyl) sulfide multiple interactions ISO H2AX (Homo sapiens) 6480464 pifithrin promotes the reaction [Mustard Gas results in increased phosphorylation of H2AX protein] CTD PMID:25448276 H2ax Rat bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of H2AX protein CTD PMID:30543897 H2ax Rat bis(2-ethylhexyl) phthalate increases phosphorylation ISO H2ax (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of H2AX protein CTD PMID:30939196|PMID:33234378|PMID:34492810|PMID:36423848 H2ax Rat bis(2-ethylhexyl) phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 [Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased phosphorylation of H2AX protein CTD PMID:30939196 H2ax Rat bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of H2AX protein CTD PMID:37258237 H2ax Rat bis(2-ethylhexyl) phthalate increases expression ISO H2ax (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of H2AX protein CTD PMID:26845775|PMID:28771232 H2ax Rat bis(2-ethylhexyl) phthalate increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of H2AX protein CTD PMID:30543897 H2ax Rat bis(2-ethylhexyl) phthalate multiple interactions ISO H2AX (Homo sapiens) 6480464 Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of H2AX protein modified form]; more ... CTD PMID:30543897|PMID:30720231 H2ax Rat bisphenol A increases expression ISO H2AX (Homo sapiens) 6480464 bisphenol A results in increased expression of H2AX mRNA; bisphenol A results in increased expression more ... CTD PMID:16462019|PMID:16474171|PMID:25933419|PMID:29275510 H2ax Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of H2AX mRNA CTD PMID:32145629 H2ax Rat bisphenol A increases expression ISO H2ax (Mus musculus) 6480464 bisphenol A results in increased expression of H2AX mRNA CTD PMID:32156529 H2ax Rat bisphenol A affects expression ISO H2AX (Homo sapiens) 6480464 bisphenol A affects the expression of H2AX mRNA CTD PMID:30903817 H2ax Rat bisphenol A increases phosphorylation ISO H2AX (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of H2AX protein CTD PMID:29128613|PMID:32466334 H2ax Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:23788033|PMID:26496021|PMID:36041667 H2ax Rat bisphenol A multiple interactions ISO H2ax (Mus musculus) 6480464 bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium more ... CTD PMID:25693136|PMID:33239236 H2ax Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of H2AX protein CTD PMID:23788033 H2ax Rat bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of H2AX protein CTD PMID:29128613 H2ax Rat bisphenol A decreases expression ISO H2AX (Homo sapiens) 6480464 bisphenol A results in decreased expression of H2AX mRNA; bisphenol A results in decreased expression more ... CTD PMID:29275510|PMID:34186270 H2ax Rat bisphenol A decreases expression ISO H2ax (Mus musculus) 6480464 bisphenol A results in decreased expression of H2AX mRNA CTD PMID:30245210 H2ax Rat bisphenol A multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of H2AX protein]; bisphenol A more ... CTD PMID:23227178|PMID:25933419|PMID:29128613 H2ax Rat bisphenol AF multiple interactions ISO H2AX (Homo sapiens) 6480464 [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of H2AX protein; [CYP1A1 protein results more ... CTD PMID:32244372|PMID:35395335 H2ax Rat bisphenol AF multiple interactions ISO H2ax (Mus musculus) 6480464 Fulvestrant inhibits the reaction [bisphenol AF results in decreased expression of H2AX protein] CTD PMID:36098747 H2ax Rat bisphenol AF increases expression ISO H2AX (Homo sapiens) 6480464 bisphenol AF results in increased expression of H2AX protein CTD PMID:32244372 H2ax Rat bisphenol AF decreases expression ISO H2ax (Mus musculus) 6480464 bisphenol AF results in decreased expression of H2AX mRNA; bisphenol AF results in decreased expression more ... CTD PMID:36098747 H2ax Rat Bisphenol B increases expression ISO H2ax (Mus musculus) 6480464 bisphenol B results in increased expression of H2AX protein CTD PMID:33392205 H2ax Rat Bisphenol B increases expression ISO H2AX (Homo sapiens) 6480464 bisphenol B results in increased expression of H2AX protein CTD PMID:34186270 H2ax Rat bisphenol F increases expression ISO H2ax (Mus musculus) 6480464 bisphenol F results in increased expression of H2AX protein CTD PMID:29102535 H2ax Rat bisphenol F increases expression ISO H2AX (Homo sapiens) 6480464 bisphenol F results in increased expression of H2AX protein CTD PMID:34186270 H2ax Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... CTD PMID:36041667 H2ax Rat bisphenol F multiple interactions ISO H2AX (Homo sapiens) 6480464 [bisphenol F co-treated with cylindrospermopsin] results in increased expression of H2AX protein CTD PMID:32244372 H2ax Rat bisphenol F decreases phosphorylation EXP 6480464 bisphenol F results in decreased phosphorylation of H2AX protein CTD PMID:37837293 H2ax Rat bleomycin A2 increases expression ISO H2AX (Homo sapiens) 6480464 Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 H2ax Rat bortezomib multiple interactions ISO H2AX (Homo sapiens) 6480464 [Bortezomib co-treated with romidepsin] results in increased phosphorylation of H2AX protein; Acetylcysteine inhibits the reaction more ... CTD PMID:15173094|PMID:16778179 H2ax Rat bortezomib decreases phosphorylation ISO H2AX (Homo sapiens) 6480464 Bortezomib results in decreased phosphorylation of H2AX protein CTD PMID:32482060 H2ax Rat bortezomib multiple interactions EXP 6480464 Bortezomib inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; Bortezomib inhibits the more ... CTD PMID:17875725 H2ax Rat bortezomib increases expression ISO H2AX (Homo sapiens) 6480464 Bortezomib results in increased expression of H2AX protein modified form CTD PMID:16778179|PMID:18790767 H2ax Rat brequinar decreases expression ISO H2AX (Homo sapiens) 6480464 brequinar results in decreased expression of H2AX mRNA CTD PMID:39900124 H2ax Rat bromoethene increases phosphorylation EXP 6480464 vinyl bromide results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat bupivacaine multiple interactions ISO H2ax (Mus musculus) 6480464 Glucose promotes the reaction [Bupivacaine results in increased expression of H2AX protein] CTD PMID:31672611 H2ax Rat bupivacaine increases expression ISO H2ax (Mus musculus) 6480464 Bupivacaine results in increased expression of H2AX protein CTD PMID:31672611 H2ax Rat busulfan increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Busulfan results in increased phosphorylation of H2AX protein CTD PMID:18339423 H2ax Rat busulfan multiple interactions ISO H2AX (Homo sapiens) 6480464 [Clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased expression of H2AX protein CTD PMID:20933509 H2ax Rat Butylbenzyl phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of H2AX protein] CTD PMID:36756972 H2ax Rat Butylbenzyl phthalate increases phosphorylation ISO H2ax (Mus musculus) 6480464 butylbenzyl phthalate results in increased phosphorylation of H2AX protein CTD PMID:36756972 H2ax Rat butyric acid decreases expression EXP 6480464 Butyric Acid results in decreased expression of H2AX mRNA CTD PMID:12800193 H2ax Rat butyric acid multiple interactions ISO H2AX (Homo sapiens) 6480464 Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased more ... CTD PMID:36399157 H2ax Rat butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of H2AX protein CTD PMID:25070040 H2ax Rat cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of H2AX protein CTD PMID:27658547 H2ax Rat cadmium atom increases phosphorylation ISO H2ax (Mus musculus) 6480464 Cadmium results in increased phosphorylation of H2AX protein CTD PMID:31521246 H2ax Rat cadmium atom multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results more ... CTD PMID:30804470 H2ax Rat cadmium atom multiple interactions ISO H2ax (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of H2AX more ... CTD PMID:35870590|PMID:38944328 H2ax Rat cadmium atom increases expression ISO H2ax (Mus musculus) 6480464 Cadmium results in increased expression of H2AX protein CTD PMID:33396178|PMID:38563870|PMID:38944328 H2ax Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of H2AX more ... CTD PMID:33031904 H2ax Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of H2AX protein CTD PMID:22457795 H2ax Rat cadmium dichloride multiple interactions ISO H2ax (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of H2AX more ... CTD PMID:35870590 H2ax Rat cadmium dichloride increases expression ISO H2AX (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of H2AX protein CTD PMID:39778856 H2ax Rat cadmium dichloride increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of H2AX protein CTD PMID:39778856 H2ax Rat cadmium dichloride multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results more ... CTD PMID:30804470 H2ax Rat cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of H2AX protein CTD PMID:37451666 H2ax Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of H2AX more ... CTD PMID:33031904|PMID:37451666 H2ax Rat cadmium dichloride affects expression ISO H2ax (Mus musculus) 6480464 Cadmium Chloride affects the expression of H2AX mRNA CTD PMID:18974090 H2ax Rat caffeine multiple interactions ISO H2AX (Homo sapiens) 6480464 Caffeine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; Caffeine inhibits the more ... CTD PMID:15975956|PMID:16777994|PMID:20888899|PMID:24069304|PMID:26231820|PMID:33971260 H2ax Rat caffeine multiple interactions EXP 6480464 [Caffeine co-treated with Ephedrine] results in increased phosphorylation of H2AX protein CTD PMID:15537744 H2ax Rat calciol decreases expression ISO H2AX (Homo sapiens) 6480464 Cholecalciferol results in decreased expression of H2AX protein CTD PMID:23363784 H2ax Rat calcitriol decreases expression ISO H2AX (Homo sapiens) 6480464 Calcitriol results in decreased expression of H2AX mRNA CTD PMID:21592394 H2ax Rat calcitriol multiple interactions ISO H2AX (Homo sapiens) 6480464 [salinomycin co-treated with Calcitriol] results in decreased expression of H2AX mRNA; [Testosterone co-treated with Calcitriol] more ... CTD PMID:21592394|PMID:35914560 H2ax Rat calcium silicate decreases expression ISO H2AX (Homo sapiens) 6480464 calcium silicate results in decreased expression of H2AX protein CTD PMID:38301883 H2ax Rat camptothecin multiple interactions ISO H2AX (Homo sapiens) 6480464 3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide inhibits the reaction [Camptothecin results in increased expression of H2AX protein modified form]; [Aminacrine more ... CTD PMID:21227924|PMID:21693595|PMID:22302033|PMID:25269479|PMID:25772433|PMID:26928355|PMID:30720231 H2ax Rat camptothecin increases expression ISO H2ax (Mus musculus) 6480464 Camptothecin results in increased expression of H2AX protein CTD PMID:17875725 H2ax Rat camptothecin increases expression EXP 6480464 Camptothecin results in increased expression of H2AX protein CTD PMID:17875725 H2ax Rat camptothecin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Camptothecin results in increased phosphorylation of H2AX protein CTD PMID:21646468|PMID:32482060 H2ax Rat camptothecin increases expression ISO H2AX (Homo sapiens) 6480464 Camptothecin results in increased expression of H2AX protein; Camptothecin results in increased expression of H2AX more ... CTD PMID:21227924|PMID:22302033|PMID:25269479|PMID:25772433|PMID:30720231 H2ax Rat cannabidiol multiple interactions ISO H2AX (Homo sapiens) 6480464 Cannabidiol promotes the reaction [Dronabinol results in increased expression of H2AX protein modified form]; Cannabidiol more ... CTD PMID:27769052|PMID:38342230 H2ax Rat cannabidiol increases expression ISO H2AX (Homo sapiens) 6480464 Cannabidiol results in increased expression of H2AX protein modified form CTD PMID:27769052 H2ax Rat capsaicin increases localization ISO H2AX (Homo sapiens) 6480464 Capsaicin results in increased localization of H2AX protein CTD PMID:22226932 H2ax Rat carbamate ester multiple interactions ISO H2AX (Homo sapiens) 6480464 Carbamates analog results in increased phosphorylation of and results in increased activity of H2AX protein CTD PMID:19376255 H2ax Rat carbamate ester increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Carbamates analog results in increased phosphorylation of H2AX protein CTD PMID:19111005 H2ax Rat carbamazepine increases expression ISO H2AX (Homo sapiens) 6480464 Carbamazepine results in increased expression of H2AX protein CTD PMID:36995427 H2ax Rat carbon nanotube increases expression ISO H2ax (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of H2AX mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25554681 H2ax Rat carbon nanotube increases expression ISO H2AX (Homo sapiens) 6480464 Nanotubes, Carbon results in increased expression of H2AX protein CTD PMID:32493873 H2ax Rat carboplatin increases expression ISO H2AX (Homo sapiens) 6480464 Carboplatin results in increased expression of H2AX protein CTD PMID:22302033 H2ax Rat carboplatin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Carboplatin results in increased phosphorylation of H2AX protein CTD PMID:37708916 H2ax Rat carboplatin multiple interactions ISO H2AX (Homo sapiens) 6480464 palbociclib inhibits the reaction [Carboplatin results in increased expression of H2AX protein]; phellopterin promotes the more ... CTD PMID:22302033|PMID:37708916 H2ax Rat carmustine decreases expression ISO H2AX (Homo sapiens) 6480464 Carmustine results in decreased expression of H2AX mRNA CTD PMID:15980968 H2ax Rat carmustine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Carmustine results in increased phosphorylation of H2AX protein CTD PMID:20472715 H2ax Rat carmustine multiple interactions ISO H2AX (Homo sapiens) 6480464 MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes more ... CTD PMID:20472715 H2ax Rat carmustine affects localization ISO H2AX (Homo sapiens) 6480464 Carmustine affects the localization of H2AX protein CTD PMID:20472715 H2ax Rat carteolol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Carteolol results in increased phosphorylation of H2AX protein CTD PMID:37120125 H2ax Rat celecoxib multiple interactions ISO H2AX (Homo sapiens) 6480464 Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 H2ax Rat CGP 52608 multiple interactions ISO H2AX (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to H2AX gene] CTD PMID:28238834 H2ax Rat chlorambucil increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Chlorambucil analog results in increased phosphorylation of H2AX protein; Chlorambucil results in increased phosphorylation of more ... CTD PMID:16861886|PMID:32482060 H2ax Rat chlordecone increases expression ISO H2ax (Mus musculus) 6480464 Chlordecone results in increased expression of H2AX protein modified form CTD PMID:31084621 H2ax Rat chlorite multiple interactions EXP 6480464 chlorite promotes the reaction [Bromates results in increased phosphorylation of H2AX protein] CTD PMID:21864635 H2ax Rat chloropicrin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 chloropicrin results in increased phosphorylation of H2AX protein CTD PMID:31884112 H2ax Rat chloropicrin multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [chloropicrin results in increased phosphorylation of H2AX protein] CTD PMID:31884112 H2ax Rat chloroprene increases expression ISO H2ax (Mus musculus) 6480464 Chloroprene results in increased expression of H2AX mRNA CTD PMID:23125180 H2ax Rat chlorpyrifos increases expression ISO H2AX (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of H2AX protein CTD PMID:32156659 H2ax Rat chlorpyrifos multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat chlorpyrifos decreases expression ISO H2ax (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of H2AX mRNA CTD PMID:37019170 H2ax Rat cholesterol multiple interactions ISO H2ax (Mus musculus) 6480464 bisphenol A promotes the reaction [Cholesterol results in increased phosphorylation of H2AX protein]; Resveratrol inhibits more ... CTD PMID:33239236 H2ax Rat cholesterol increases phosphorylation ISO H2ax (Mus musculus) 6480464 Cholesterol results in increased phosphorylation of H2AX protein CTD PMID:33239236 H2ax Rat choline multiple interactions ISO H2ax (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased phosphorylation more ... CTD PMID:20548288 H2ax Rat chromium atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated more ... CTD PMID:38605572 H2ax Rat chromium(6+) increases ubiquitination ISO H2AX (Homo sapiens) 6480464 chromium hexavalent ion results in increased ubiquitination of H2AX protein CTD PMID:25288669 H2ax Rat chromium(6+) increases ubiquitination ISO H2ax (Mus musculus) 6480464 chromium hexavalent ion results in increased ubiquitination of H2AX protein CTD PMID:25288669 H2ax Rat chromium(6+) increases phosphorylation ISO H2ax (Mus musculus) 6480464 chromium hexavalent ion results in increased phosphorylation of H2AX protein CTD PMID:25288669 H2ax Rat chromium(6+) increases expression ISO H2ax (Mus musculus) 6480464 chromium hexavalent ion results in increased expression of H2AX protein CTD PMID:25352572|PMID:38563870 H2ax Rat chromium(6+) multiple interactions ISO H2ax (Mus musculus) 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression more ... CTD PMID:25288669|PMID:35643323 H2ax Rat chromium(6+) increases phosphorylation ISO H2AX (Homo sapiens) 6480464 chromium hexavalent ion results in increased phosphorylation of H2AX protein CTD PMID:25288669 H2ax Rat chromium(6+) multiple interactions ISO H2AX (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... CTD PMID:25288669|PMID:38479592 H2ax Rat chromone increases expression ISO H2AX (Homo sapiens) 6480464 4-chromone analog results in increased expression of H2AX protein modified form CTD PMID:30256521 H2ax Rat Cinobufagin increases expression ISO H2AX (Homo sapiens) 6480464 cinobufagin results in increased expression of H2AX protein CTD PMID:35427566 H2ax Rat cisplatin increases expression ISO H2AX (Homo sapiens) 6480464 Cisplatin results in increased expression of H2AX mRNA; Cisplatin results in increased expression of H2AX more ... CTD PMID:21500194|PMID:22383522|PMID:22659117|PMID:24994473|PMID:24999622|PMID:25940438|PMID:27594783|PMID:28371273|PMID:29567272|PMID:30804470|PMID:33545341|PMID:34822033|PMID:37802411|PMID:39461470 H2ax Rat cisplatin increases phosphorylation ISO H2ax (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of H2AX protein CTD PMID:21285353|PMID:21593482|PMID:22006019|PMID:26193055 H2ax Rat cisplatin multiple interactions ISO H2ax (Mus musculus) 6480464 erdosteine inhibits the reaction [Cisplatin results in increased phosphorylation of H2AX protein]; Lovastatin inhibits the more ... CTD PMID:21324906|PMID:26193055|PMID:26739623 H2ax Rat cisplatin increases expression ISO H2ax (Mus musculus) 6480464 Cisplatin results in increased expression of H2AX protein; Cisplatin results in increased expression of H2AX more ... CTD PMID:26723870|PMID:26739623 H2ax Rat cisplatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form] CTD PMID:26739623 H2ax Rat cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of H2AX protein modified form CTD PMID:26739623 H2ax Rat cisplatin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Cisplatin results in increased phosphorylation of H2AX protein CTD PMID:20145152|PMID:21285353|PMID:21324906|PMID:21356574|PMID:21445297|PMID:21875941|PMID:23861973|PMID:26721606|PMID:32482060|PMID:34510228|PMID:36425765 H2ax Rat cisplatin multiple interactions ISO H2AX (Homo sapiens) 6480464 (+)-JQ1 compound promotes the reaction [Cisplatin results in increased expression of H2AX protein]; [MIR138-1 results more ... CTD PMID:20145152|PMID:21324906|PMID:21356574|PMID:21445297|PMID:21693595|PMID:21750216|PMID:21875941|PMID:22383522|PMID:23861973|PMID:24999622|PMID:25940438|PMID:26721606|PMID:29567272|PMID:34822033|PMID:36425765|PMID:37802411|PMID:39461470 H2ax Rat clofarabine multiple interactions ISO H2AX (Homo sapiens) 6480464 [Clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased expression of H2AX protein CTD PMID:20933509 H2ax Rat cobalt atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated more ... CTD PMID:38605572 H2ax Rat cobalt dichloride multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation more ... CTD PMID:22172632 H2ax Rat cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of H2AX mRNA CTD PMID:24386269 H2ax Rat cobalt dichloride decreases expression ISO H2AX (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of H2AX mRNA CTD PMID:19376846 H2ax Rat cobalt dichloride increases phosphorylation ISO H2AX (Homo sapiens) 6480464 cobaltous chloride results in increased phosphorylation of H2AX protein CTD PMID:22172632 H2ax Rat copper atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased expression of H2AX more ... CTD PMID:22659117|PMID:35809665 H2ax Rat copper atom increases expression ISO H2AX (Homo sapiens) 6480464 Copper results in increased expression of H2AX protein CTD PMID:35809665 H2ax Rat copper(0) multiple interactions ISO H2AX (Homo sapiens) 6480464 [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased expression of H2AX more ... CTD PMID:22659117|PMID:35809665 H2ax Rat copper(0) increases expression ISO H2AX (Homo sapiens) 6480464 Copper results in increased expression of H2AX protein CTD PMID:35809665 H2ax Rat copper(II) sulfate decreases expression ISO H2AX (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of H2AX mRNA CTD PMID:19549813 H2ax Rat corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of H2AX protein CTD PMID:38259729 H2ax Rat corticosterone multiple interactions EXP 6480464 [Ethanol co-treated with Corticosterone] results in increased expression of H2AX protein CTD PMID:38259729 H2ax Rat coumestrol multiple interactions ISO H2AX (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AX mRNA; [Coumestrol co-treated with Resveratrol] more ... CTD PMID:19167446 H2ax Rat coumestrol increases expression ISO H2AX (Homo sapiens) 6480464 Coumestrol results in increased expression of H2AX mRNA; Coumestrol results in increased expression of H2AX more ... CTD PMID:19167446|PMID:28986287 H2ax Rat crizotinib multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Crizotinib results in increased phosphorylation of H2AX protein] CTD PMID:31639374 H2ax Rat crizotinib increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Crizotinib results in increased phosphorylation of H2AX protein CTD PMID:31639374 H2ax Rat crocidolite asbestos decreases expression ISO H2AX (Homo sapiens) 6480464 Asbestos, Crocidolite results in decreased expression of H2AX protein CTD PMID:38301883 H2ax Rat crocidolite asbestos increases secretion ISO H2AX (Homo sapiens) 6480464 Asbestos, Crocidolite results in increased secretion of H2AX protein CTD PMID:38605572 H2ax Rat CU-O LINKAGE increases expression ISO H2AX (Homo sapiens) 6480464 cupric oxide analog results in increased expression of H2AX protein CTD PMID:27270449 H2ax Rat CU-O LINKAGE decreases expression ISO H2AX (Homo sapiens) 6480464 cupric oxide results in decreased expression of H2AX mRNA CTD PMID:22077320 H2ax Rat curcumin multiple interactions ISO H2AX (Homo sapiens) 6480464 [Curcumin co-treated with Metribolone] results in increased phosphorylation of H2AX protein; [Isoflavones co-treated with Curcumin] more ... CTD PMID:21134073 H2ax Rat curcumin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Curcumin results in increased phosphorylation of H2AX protein CTD PMID:19401701|PMID:21134073 H2ax Rat CX-5461 increases expression ISO H2AX (Homo sapiens) 6480464 CX 5461 results in increased expression of H2AX protein CTD PMID:28211448 H2ax Rat cyclophosphamide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Cyclophosphamide results in increased phosphorylation of H2AX protein CTD PMID:32482060|PMID:34510228 H2ax Rat cyclophosphamide increases expression ISO H2ax (Mus musculus) 6480464 Cyclophosphamide results in increased expression of H2AX protein CTD PMID:37690746|PMID:39952379 H2ax Rat cyclophosphamide increases phosphorylation EXP 6480464 Cyclophosphamide results in increased phosphorylation of H2AX protein CTD PMID:33211169 H2ax Rat cyclophosphamide multiple interactions ISO H2ax (Mus musculus) 6480464 Dexrazoxane inhibits the reaction [Cyclophosphamide results in increased expression of H2AX protein]; TRPM2 protein affects more ... CTD PMID:37690746|PMID:39952379 H2ax Rat cyclosporin A decreases expression ISO H2AX (Homo sapiens) 6480464 Cyclosporine results in decreased expression of H2AX mRNA CTD PMID:20106945|PMID:21632981|PMID:25562108 H2ax Rat cyhalothrin multiple interactions ISO H2AX (Homo sapiens) 6480464 [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in more ... CTD PMID:22389207|PMID:34503147 H2ax Rat cylindrospermopsin increases expression ISO H2AX (Homo sapiens) 6480464 cylindrospermopsin results in increased expression of H2AX protein CTD PMID:30905859|PMID:32244372 H2ax Rat cylindrospermopsin multiple interactions ISO H2AX (Homo sapiens) 6480464 [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of H2AX protein; [bisphenol F co-treated more ... CTD PMID:32244372 H2ax Rat cypermethrin increases phosphorylation EXP 6480464 cypermethrin results in increased phosphorylation of H2AX protein CTD PMID:35512476 H2ax Rat cyprodinil multiple interactions ISO H2AX (Homo sapiens) 6480464 [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in more ... CTD PMID:22389207|PMID:34503147 H2ax Rat cyprodinil increases phosphorylation ISO H2AX (Homo sapiens) 6480464 cyprodinil results in increased phosphorylation of H2AX protein CTD PMID:22389207 H2ax Rat cytarabine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Cytarabine results in increased phosphorylation of H2AX protein CTD PMID:19628630|PMID:34510228 H2ax Rat D-glucitol increases expression ISO H2AX (Homo sapiens) 6480464 Sorbitol results in increased expression of H2AX protein CTD PMID:30804470 H2ax Rat D-glucose multiple interactions ISO H2ax (Mus musculus) 6480464 Glucose promotes the reaction [Bupivacaine results in increased expression of H2AX protein] CTD PMID:31672611 H2ax Rat D-glucose increases expression ISO H2ax (Mus musculus) 6480464 Glucose results in increased expression of H2AX protein CTD PMID:31672611 H2ax Rat daunorubicin affects expression ISO H2AX (Homo sapiens) 6480464 Daunorubicin affects the expression of H2AX mRNA CTD PMID:27780733 H2ax Rat daunorubicin increases expression ISO H2AX (Homo sapiens) 6480464 Daunorubicin results in increased expression of H2AX protein CTD PMID:34963561 H2ax Rat DDE increases expression ISO H2AX (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of H2AX mRNA CTD PMID:38568856 H2ax Rat decabromodiphenyl ether increases expression ISO H2ax (Mus musculus) 6480464 decabromobiphenyl ether results in increased expression of H2AX mRNA; decabromobiphenyl ether results in increased expression more ... CTD PMID:34936917 H2ax Rat desferrioxamine B decreases expression ISO H2AX (Homo sapiens) 6480464 Deferoxamine results in decreased expression of H2AX protein CTD PMID:38483099 H2ax Rat desferrioxamine B decreases expression EXP 6480464 Deferoxamine results in decreased expression of H2AX protein CTD PMID:38483099 H2ax Rat desferrioxamine B multiple interactions EXP 6480464 PRKCD protein affects the reaction [Deferoxamine results in increased phosphorylation of H2AX protein] CTD PMID:17563398 H2ax Rat desferrioxamine B increases phosphorylation EXP 6480464 Deferoxamine results in increased phosphorylation of H2AX protein CTD PMID:17563398 H2ax Rat dexamethasone multiple interactions ISO H2AX (Homo sapiens) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX more ... CTD PMID:26424790 H2ax Rat diallyl trisulfide decreases expression ISO H2AX (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of H2AX mRNA CTD PMID:34995734 H2ax Rat diarsenic trioxide increases expression ISO H2ax (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of H2AX protein modified form CTD PMID:28265077 H2ax Rat diarsenic trioxide increases expression ISO H2AX (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of H2AX protein; Arsenic Trioxide results in increased expression more ... CTD PMID:28265077|PMID:28318385|PMID:31597699 H2ax Rat diarsenic trioxide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of H2AX protein CTD PMID:16891316|PMID:23861973 H2ax Rat diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of H2AX protein CTD PMID:23337567 H2ax Rat diarsenic trioxide multiple interactions ISO H2AX (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with ruxolitinib] results in increased phosphorylation of H2AX protein; [Arsenic Trioxide co-treated more ... CTD PMID:18636201|PMID:23861973|PMID:28318385|PMID:30012499 H2ax Rat diarsenic trioxide multiple interactions EXP 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of H2AX protein] CTD PMID:23337567 H2ax Rat diazinon multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat dibenz[a,h]anthracene increases expression ISO H2AX (Homo sapiens) 6480464 1,2,5,6-dibenzanthracene metabolite results in increased expression of H2AX protein CTD PMID:31051210 H2ax Rat Dibenz[a,j]acridine increases expression ISO H2AX (Homo sapiens) 6480464 dibenzacridine metabolite results in increased expression of H2AX protein CTD PMID:31051210 H2ax Rat Dibenz[c,h]acridine increases expression ISO H2AX (Homo sapiens) 6480464 dibenz(c,h)acridine metabolite results in increased expression of H2AX protein CTD PMID:31051210 H2ax Rat dibenziodolium multiple interactions ISO H2AX (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Aflatoxin B1 results in increased expression of H2AX protein]; diphenyleneiodonium inhibits more ... CTD PMID:34396909 H2ax Rat dibenzo[a,l]pyrene multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(morpholin-4-yl)benzo(h)chromen-4-one inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of H2AX protein] CTD PMID:31838185 H2ax Rat dibenzo[a,l]pyrene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 dibenzo(a,l)pyrene results in increased phosphorylation of H2AX protein CTD PMID:31838185 H2ax Rat dibutyl phthalate decreases expression ISO H2ax (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of H2AX mRNA CTD PMID:17361019|PMID:21266533 H2ax Rat dibutyl phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 AKT activator SC79 inhibits the reaction [Dibutyl Phthalate results in increased expression of H2AX protein]; more ... CTD PMID:30952838 H2ax Rat dibutyl phthalate increases expression ISO H2ax (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of H2AX protein CTD PMID:30952838 H2ax Rat dichlorine increases expression ISO H2ax (Mus musculus) 6480464 Chlorine results in increased expression of H2AX protein CTD PMID:36690086 H2ax Rat diclofenac increases expression ISO H2AX (Homo sapiens) 6480464 Diclofenac results in increased expression of H2AX protein CTD PMID:32087850 H2ax Rat diepoxybutane multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of H2AX protein modified form] CTD PMID:25633853 H2ax Rat diepoxybutane increases expression ISO H2ax (Mus musculus) 6480464 diepoxybutane results in increased expression of H2AX protein modified form CTD PMID:25633853 H2ax Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat dihydroxyacetone increases expression ISO H2AX (Homo sapiens) 6480464 Dihydroxyacetone results in increased expression of H2AX protein CTD PMID:32506039 H2ax Rat dimethoate multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat dimethocaine multiple interactions ISO H2AX (Homo sapiens) 6480464 [NAT2 protein results in increased susceptibility to dimethocaine] which results in increased expression of H2AX more ... CTD PMID:36138126 H2ax Rat dimethyl sulfoxide increases expression ISO H2AX (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of H2AX mRNA CTD PMID:39709020 H2ax Rat dioxygen decreases expression ISO H2AX (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of H2AX mRNA; Oxygen deficiency results in decreased expression more ... CTD PMID:26516004|PMID:38909692 H2ax Rat dioxygen multiple interactions ISO H2AX (Homo sapiens) 6480464 Oxygen deficiency inhibits the reaction [ferric oxide analog results in increased expression of H2AX protein]; more ... CTD PMID:27270449 H2ax Rat disodium selenite increases expression ISO H2AX (Homo sapiens) 6480464 Sodium Selenite results in increased expression of H2AX mRNA CTD PMID:18175754 H2ax Rat disodium selenite increases expression ISO H2ax (Mus musculus) 6480464 Sodium Selenite results in increased expression of H2AX protein CTD PMID:37142062 H2ax Rat Disperse Blue 1 increases phosphorylation EXP 6480464 Disperse Blue 1 results in increased phosphorylation of H2AX protein CTD PMID:33211169 H2ax Rat disulfiram multiple interactions ISO H2AX (Homo sapiens) 6480464 Disulfiram inhibits the reaction [captax results in increased expression of H2AX protein]; Disulfiram inhibits the more ... CTD PMID:28300663|PMID:29722447|PMID:35279910 H2ax Rat disulfiram increases expression ISO H2AX (Homo sapiens) 6480464 Disulfiram results in increased expression of H2AX protein CTD PMID:34830855 H2ax Rat dorsomorphin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 dorsomorphin results in increased phosphorylation of H2AX protein CTD PMID:23274516 H2ax Rat dorsomorphin multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of H2AX protein] CTD PMID:23274516 H2ax Rat doxorubicin multiple interactions ISO H2AX (Homo sapiens) 6480464 [TP53 protein affects the susceptibility to Doxorubicin] which affects the expression of H2AX mRNA; Acetylcysteine more ... CTD PMID:15489221|PMID:22302033|PMID:22751436|PMID:23899529|PMID:27634759|PMID:30769864|PMID:32107588|PMID:34783124|PMID:36634904 H2ax Rat doxorubicin decreases expression ISO H2AX (Homo sapiens) 6480464 Doxorubicin results in decreased expression of H2AX mRNA CTD PMID:29803840|PMID:36634904 H2ax Rat doxorubicin increases phosphorylation ISO H2ax (Mus musculus) 6480464 Doxorubicin results in increased phosphorylation of H2AX protein CTD PMID:22712078|PMID:31368505 H2ax Rat doxorubicin multiple interactions EXP 6480464 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; [Poly(ADP-ribose) Polymerase Inhibitors more ... CTD PMID:17875725|PMID:24902966|PMID:29913208 H2ax Rat doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of H2AX protein; Doxorubicin results in increased expression of H2AX more ... CTD PMID:17875725|PMID:24902966|PMID:29913208 H2ax Rat doxorubicin multiple interactions ISO H2ax (Mus musculus) 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein modified form]; Lovastatin more ... CTD PMID:17875725|PMID:22712078|PMID:28710503 H2ax Rat doxorubicin increases expression ISO H2ax (Mus musculus) 6480464 Doxorubicin results in increased expression of H2AX protein; Doxorubicin results in increased expression of H2AX more ... CTD PMID:17875725|PMID:28710503 H2ax Rat doxorubicin affects expression ISO H2AX (Homo sapiens) 6480464 Doxorubicin affects the expression of H2AX mRNA CTD PMID:27780733 H2ax Rat doxorubicin increases expression ISO H2AX (Homo sapiens) 6480464 Doxorubicin results in increased expression of H2AX mRNA; Doxorubicin results in increased expression of H2AX more ... CTD PMID:22302033|PMID:30769864|PMID:32107588|PMID:34783124|PMID:35690182 H2ax Rat doxorubicin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of H2AX protein CTD PMID:15489221|PMID:16432175|PMID:20978201|PMID:21356574|PMID:21646468|PMID:22751436|PMID:23899529|PMID:27922187 H2ax Rat dronedarone multiple interactions ISO H2AX (Homo sapiens) 6480464 CYP2D6 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein]; CYP3A4 protein more ... CTD PMID:29616291 H2ax Rat dronedarone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Dronedarone results in increased phosphorylation of H2AX protein CTD PMID:29616291 H2ax Rat Echimidine increases expression ISO H2AX (Homo sapiens) 6480464 echimidine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat elemental selenium increases expression ISO H2AX (Homo sapiens) 6480464 Selenium results in increased expression of H2AX mRNA CTD PMID:19244175 H2ax Rat elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Acrylamide results in increased expression of H2AX protein] CTD PMID:37987225 H2ax Rat ellipticine multiple interactions ISO H2AX (Homo sapiens) 6480464 [ellipticine binds to FTL protein] which results in increased expression of H2AX protein modified form CTD PMID:30914192 H2ax Rat ellipticine increases expression ISO H2AX (Homo sapiens) 6480464 ellipticine results in increased expression of H2AX protein modified form CTD PMID:30914192 H2ax Rat emodin increases expression ISO H2AX (Homo sapiens) 6480464 Emodin results in increased expression of H2AX protein; Emodin results in increased expression of H2AX more ... CTD PMID:20855424|PMID:34492313|PMID:36893906 H2ax Rat emodin multiple interactions ISO H2AX (Homo sapiens) 6480464 TOP2A affects the reaction [Emodin results in increased expression of H2AX protein modified form] CTD PMID:20855424 H2ax Rat empagliflozin multiple interactions ISO H2ax (Mus musculus) 6480464 empagliflozin inhibits the reaction [Sorafenib results in increased expression of H2AX protein] CTD PMID:38884142 H2ax Rat enilconazole multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat Enterolactone multiple interactions ISO H2AX (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AX mRNA CTD PMID:19167446 H2ax Rat entinostat increases phosphorylation ISO H2AX (Homo sapiens) 6480464 entinostat results in increased phosphorylation of H2AX protein CTD PMID:34665271 H2ax Rat epothilone A multiple interactions ISO H2AX (Homo sapiens) 6480464 [epothilone A co-treated with Metformin] results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat epothilone A increases expression ISO H2AX (Homo sapiens) 6480464 epothilone A results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat erastin increases expression ISO H2AX (Homo sapiens) 6480464 erastin results in increased expression of H2AX protein CTD PMID:30804470 H2ax Rat erdosteine multiple interactions ISO H2ax (Mus musculus) 6480464 erdosteine inhibits the reaction [Cisplatin results in increased phosphorylation of H2AX protein] CTD PMID:26193055 H2ax Rat Erionite multiple interactions ISO H2AX (Homo sapiens) 6480464 [erionite results in increased abundance of Aluminum] which results in increased phosphorylation of H2AX protein CTD PMID:38605572 H2ax Rat erlotinib hydrochloride multiple interactions ISO H2AX (Homo sapiens) 6480464 Erlotinib Hydrochloride promotes the reaction [Resveratrol results in increased expression of H2AX protein modified form]; more ... CTD PMID:25895606 H2ax Rat erlotinib hydrochloride increases expression ISO H2AX (Homo sapiens) 6480464 Erlotinib Hydrochloride results in increased expression of H2AX protein modified form CTD PMID:25895606 H2ax Rat erucifoline increases expression ISO H2AX (Homo sapiens) 6480464 erucifoline results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat estragole increases expression EXP 6480464 estragole results in increased expression of H2AX protein modified form CTD PMID:29054680 H2ax Rat ethanol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Ethanol results in increased phosphorylation of H2AX protein CTD PMID:24374569 H2ax Rat ethanol multiple interactions ISO H2AX (Homo sapiens) 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of more ... CTD PMID:34192554|PMID:34405320 H2ax Rat ethanol increases expression ISO H2AX (Homo sapiens) 6480464 Ethanol results in increased expression of H2AX mRNA; Ethanol results in increased expression of H2AX more ... CTD PMID:34192554|PMID:34405320 H2ax Rat ethanol increases expression ISO H2ax (Mus musculus) 6480464 Ethanol results in increased expression of H2AX mRNA; Ethanol results in increased expression of H2AX more ... CTD PMID:34192554|PMID:34405320|PMID:37271273 H2ax Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of H2AX protein CTD PMID:38259729 H2ax Rat ethanol multiple interactions EXP 6480464 [Ethanol co-treated with Corticosterone] results in increased expression of H2AX protein CTD PMID:38259729 H2ax Rat ethanol increases phosphorylation ISO H2ax (Mus musculus) 6480464 Ethanol results in increased phosphorylation of H2AX protein CTD PMID:26629949 H2ax Rat ethanol multiple interactions ISO H2ax (Mus musculus) 6480464 [BRCA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased phosphorylation more ... CTD PMID:26629949|PMID:34192554|PMID:34405320|PMID:37271273 H2ax Rat Ethyl maltol multiple interactions ISO H2AX (Homo sapiens) 6480464 APP protein inhibits the reaction [ethyl maltol results in increased expression of H2AX protein] CTD PMID:37606557 H2ax Rat Ethyl maltol increases expression ISO H2AX (Homo sapiens) 6480464 ethyl maltol results in increased expression of H2AX protein CTD PMID:37606557 H2ax Rat ethyl methanesulfonate increases expression ISO H2AX (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of H2AX protein CTD PMID:35395335|PMID:36995427|PMID:38823534 H2ax Rat Ethylenethiourea increases phosphorylation EXP 6480464 Ethylenethiourea results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat etoposide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Etoposide results in increased phosphorylation of H2AX protein CTD PMID:20978201|PMID:21745461|PMID:25078064|PMID:32482060|PMID:34510228|PMID:37451322 H2ax Rat etoposide increases expression ISO H2ax (Mus musculus) 6480464 Etoposide results in increased expression of H2AX protein CTD PMID:17875725|PMID:20643100|PMID:33823233 H2ax Rat etoposide multiple interactions ISO H2ax (Mus musculus) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide results in increased expression of H2AX protein]; RAD54B protein affects more ... CTD PMID:17875725|PMID:20643100|PMID:33823233 H2ax Rat etoposide multiple interactions EXP 6480464 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Etoposide results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits more ... CTD PMID:17875725 H2ax Rat etoposide increases expression EXP 6480464 Etoposide results in increased expression of H2AX protein CTD PMID:17875725 H2ax Rat etoposide decreases response to substance ISO H2ax (Mus musculus) 6480464 H2AX protein results in decreased susceptibility to Etoposide CTD PMID:21555580 H2ax Rat etoposide increases expression ISO H2AX (Homo sapiens) 6480464 Etoposide results in increased expression of H2AX protein; Etoposide results in increased expression of H2AX more ... CTD PMID:22302033|PMID:26259609|PMID:28343997|PMID:35690182 H2ax Rat etoposide multiple interactions ISO H2AX (Homo sapiens) 6480464 Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the more ... CTD PMID:21745461|PMID:22302033|PMID:26259609 H2ax Rat Evodiamine multiple interactions ISO H2AX (Homo sapiens) 6480464 [tetramethylpyrazine co-treated with evodiamine] results in increased expression of H2AX protein CTD PMID:39486648 H2ax Rat fenbendazole increases expression ISO H2AX (Homo sapiens) 6480464 Fenbendazole analog results in increased expression of H2AX protein; Fenbendazole results in increased expression of more ... CTD PMID:35569513 H2ax Rat fenthion increases expression ISO H2AX (Homo sapiens) 6480464 Fenthion results in increased expression of H2AX protein CTD PMID:33221015 H2ax Rat ferric ammonium citrate increases expression EXP 6480464 ferric ammonium citrate results in increased expression of H2AX protein CTD PMID:38483099 H2ax Rat ferric ammonium citrate increases expression ISO H2AX (Homo sapiens) 6480464 ferric ammonium citrate results in increased expression of H2AX protein CTD PMID:38483099 H2ax Rat ferric oxide multiple interactions ISO H2AX (Homo sapiens) 6480464 Oxygen deficiency inhibits the reaction [ferric oxide analog results in increased expression of H2AX protein] CTD PMID:27270449 H2ax Rat ferric oxide increases expression ISO H2AX (Homo sapiens) 6480464 ferric oxide analog results in increased expression of H2AX protein CTD PMID:27270449 H2ax Rat ferrostatin-1 multiple interactions ISO H2ax (Mus musculus) 6480464 ferrostatin-1 inhibits the reaction [triptolide results in increased expression of H2AX protein] CTD PMID:38960301 H2ax Rat fisetin multiple interactions EXP 6480464 fisetin inhibits the reaction [IL1B protein results in increased expression of H2AX protein] CTD PMID:38278314 H2ax Rat fisetin affects expression EXP 6480464 fisetin affects the expression of H2AX protein CTD PMID:38278314 H2ax Rat flavanones multiple interactions ISO H2AX (Homo sapiens) 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Flavanones results in increased phosphorylation of H2AX protein]; CDKN1A gene mutant more ... CTD PMID:21616090 H2ax Rat flavanones increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Flavanones results in increased phosphorylation of H2AX protein CTD PMID:21616090 H2ax Rat flavokawain B increases phosphorylation ISO H2AX (Homo sapiens) 6480464 flavokawain B results in increased phosphorylation of H2AX protein CTD PMID:30025493 H2ax Rat fludioxonil multiple interactions ISO H2AX (Homo sapiens) 6480464 [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in more ... CTD PMID:22389207|PMID:34503147 H2ax Rat fludioxonil increases phosphorylation ISO H2AX (Homo sapiens) 6480464 fludioxonil results in increased phosphorylation of H2AX protein CTD PMID:22389207 H2ax Rat fluoranthene multiple interactions ISO H2ax (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of H2AX mRNA CTD PMID:28329830 H2ax Rat fluoranthene multiple interactions ISO H2AX (Homo sapiens) 6480464 [fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of H2AX protein; [pyrene co-treated with fluoranthene more ... CTD PMID:33249052 H2ax Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of H2AX mRNA CTD PMID:24793618 H2ax Rat folic acid multiple interactions ISO H2ax (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of H2AX mRNA; [Methionine deficiency co-treated more ... CTD PMID:20548288|PMID:22206623 H2ax Rat folic acid affects phosphorylation ISO H2ax (Mus musculus) 6480464 Folic Acid deficiency affects the phosphorylation of H2AX protein CTD PMID:28471487 H2ax Rat fomepizole multiple interactions ISO H2AX (Homo sapiens) 6480464 Fomepizole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein] CTD PMID:28300663 H2ax Rat formaldehyde increases expression ISO H2AX (Homo sapiens) 6480464 Formaldehyde results in increased expression of H2AX protein CTD PMID:22479348 H2ax Rat fotemustine increases expression ISO H2AX (Homo sapiens) 6480464 fotemustine results in increased expression of H2AX protein modified form CTD PMID:25125662 H2ax Rat FR900359 affects phosphorylation ISO H2AX (Homo sapiens) 6480464 FR900359 affects the phosphorylation of H2AX protein CTD PMID:37730182 H2ax Rat fructose multiple interactions ISO H2ax (Mus musculus) 6480464 [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with more ... CTD PMID:37271273 H2ax Rat fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of H2AX protein]; Fulvestrant inhibits more ... CTD PMID:23788033 H2ax Rat fulvestrant multiple interactions ISO H2ax (Mus musculus) 6480464 Fulvestrant inhibits the reaction [bisphenol AF results in decreased expression of H2AX protein]; Fulvestrant inhibits more ... CTD PMID:36098747 H2ax Rat fulvestrant multiple interactions ISO H2AX (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [Estradiol results in increased expression of H2AX protein modified form]; Fulvestrant more ... CTD PMID:31939680 H2ax Rat fumonisin B1 decreases expression ISO H2AX (Homo sapiens) 6480464 fumonisin B1 results in decreased expression of H2AX protein CTD PMID:25800559 H2ax Rat furan increases methylation EXP 6480464 furan results in increased methylation of H2AX gene CTD PMID:22079235 H2ax Rat GDP multiple interactions ISO H2AX (Homo sapiens) 6480464 Guanosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat gemcitabine multiple interactions ISO H2AX (Homo sapiens) 6480464 PIF1 protein inhibits the reaction [Gemcitabine results in increased expression of H2AX protein]; Thymidine inhibits more ... CTD PMID:37183367 H2ax Rat gemcitabine increases expression ISO H2AX (Homo sapiens) 6480464 Gemcitabine results in increased expression of H2AX protein; Gemcitabine results in increased expression of H2AX more ... CTD PMID:20798217|PMID:37183367|PMID:38000456 H2ax Rat genistein multiple interactions ISO H2AX (Homo sapiens) 6480464 ATM protein affects the reaction [Genistein results in increased phosphorylation of H2AX protein] CTD PMID:15177039 H2ax Rat genistein increases expression ISO H2AX (Homo sapiens) 6480464 Genistein results in increased expression of H2AX mRNA CTD PMID:16474171 H2ax Rat genistein increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Genistein results in increased phosphorylation of H2AX protein CTD PMID:15177039 H2ax Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of H2AX mRNA CTD PMID:33387578 H2ax Rat Gingerenone A increases expression ISO H2AX (Homo sapiens) 6480464 gingerenone A results in increased expression of H2AX protein CTD PMID:35326237 H2ax Rat Gingerenone A multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [gingerenone A results in increased expression of H2AX protein] CTD PMID:35326237 H2ax Rat ginsenoside Rg1 multiple interactions ISO H2AX (Homo sapiens) 6480464 ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of H2AX mRNA] CTD PMID:34783124 H2ax Rat Glu-P-1 increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat Glu-P-2 increases expression ISO H2AX (Homo sapiens) 6480464 Glu-P-2 results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat glucose increases expression ISO H2ax (Mus musculus) 6480464 Glucose results in increased expression of H2AX protein CTD PMID:31672611 H2ax Rat glucose multiple interactions ISO H2ax (Mus musculus) 6480464 Glucose promotes the reaction [Bupivacaine results in increased expression of H2AX protein] CTD PMID:31672611 H2ax Rat glutathione multiple interactions ISO H2ax (Mus musculus) 6480464 Glutathione inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of H2AX protein] CTD PMID:21722719 H2ax Rat glutathione multiple interactions ISO H2AX (Homo sapiens) 6480464 Glutathione inhibits the reaction [rubimaillin results in increased phosphorylation of H2AX protein] CTD PMID:35007525 H2ax Rat glycerol 2-phosphate multiple interactions ISO H2AX (Homo sapiens) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX more ... CTD PMID:26424790 H2ax Rat glyphosate increases expression ISO H2ax (Mus musculus) 6480464 Glyphosate results in increased expression of H2AX protein modified form CTD PMID:31352102 H2ax Rat GSK690693 multiple interactions ISO H2AX (Homo sapiens) 6480464 GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein] CTD PMID:34784199 H2ax Rat GTP multiple interactions ISO H2AX (Homo sapiens) 6480464 Guanosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat guanosine multiple interactions ISO H2AX (Homo sapiens) 6480464 Guanosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of more ... CTD PMID:32941855 H2ax Rat GW 4064 multiple interactions ISO H2ax (Mus musculus) 6480464 GW 4064 affects the reaction [Arsenic results in decreased expression of H2AX protein] CTD PMID:37888683 H2ax Rat Heliotrine increases expression ISO H2AX (Homo sapiens) 6480464 heliotrine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat hexachlorobenzene increases expression ISO H2AX (Homo sapiens) 6480464 Hexachlorobenzene results in increased expression of H2AX protein CTD PMID:32156659 H2ax Rat hexadecanoic acid increases expression ISO H2AX (Homo sapiens) 6480464 Palmitic Acid results in increased expression of H2AX protein CTD PMID:40023272 H2ax Rat hydrazine increases phosphorylation EXP 6480464 hydrazine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat hydrogen peroxide multiple interactions ISO H2AX (Homo sapiens) 6480464 [ERCC6 protein affects the susceptibility to Hydrogen Peroxide] which affects the expression of H2AX protein; more ... CTD PMID:18848825|PMID:25136123|PMID:25972194|PMID:28300663|PMID:35279910 H2ax Rat hydrogen peroxide multiple interactions ISO H2ax (Mus musculus) 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased phosphorylation of H2AX protein CTD PMID:31494107 H2ax Rat hydrogen peroxide increases expression ISO H2ax (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of H2AX protein CTD PMID:17875725 H2ax Rat hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of H2AX protein CTD PMID:17875725 H2ax Rat hydrogen peroxide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Hydrogen Peroxide results in increased phosphorylation of H2AX protein CTD PMID:25460656|PMID:28300663 H2ax Rat hydrogen peroxide increases expression ISO H2AX (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of H2AX mRNA; Hydrogen Peroxide results in increased expression more ... CTD PMID:25972194|PMID:28343997|PMID:29074359|PMID:35279910|PMID:37121742 H2ax Rat hydrogen peroxide decreases expression ISO H2AX (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of H2AX protein modified form CTD PMID:27655674 H2ax Rat hydroquinone multiple interactions ISO H2AX (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; 2-tert-butylhydroquinone more ... CTD PMID:17875398|PMID:21267443|PMID:22981619|PMID:26822515|PMID:27515134|PMID:28843007|PMID:30506647|PMID:35123993|PMID:39029599 H2ax Rat hydroquinone multiple interactions ISO H2ax (Mus musculus) 6480464 FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein] CTD PMID:22687461 H2ax Rat hydroquinone increases expression ISO H2ax (Mus musculus) 6480464 hydroquinone results in increased expression of H2AX protein CTD PMID:22687461|PMID:23940708 H2ax Rat hydroquinone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 hydroquinone results in increased phosphorylation of H2AX protein CTD PMID:18835433|PMID:39029599 H2ax Rat hydroquinone affects localization ISO H2AX (Homo sapiens) 6480464 hydroquinone affects the localization of H2AX protein modified form CTD PMID:20036648 H2ax Rat hydroquinone increases expression ISO H2AX (Homo sapiens) 6480464 hydroquinone results in increased expression of H2AX protein; hydroquinone results in increased expression of H2AX more ... CTD PMID:21267443|PMID:22981619|PMID:26335980|PMID:26822515|PMID:27515134|PMID:28843007|PMID:35123993 H2ax Rat hydroxychloroquine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Hydroxychloroquine results in increased phosphorylation of H2AX protein CTD PMID:38311193 H2ax Rat hydroxyurea increases expression ISO H2AX (Homo sapiens) 6480464 Hydroxyurea results in increased expression of H2AX protein; Hydroxyurea results in increased expression of H2AX more ... CTD PMID:21840268|PMID:25125662|PMID:25130544 H2ax Rat hydroxyurea increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Hydroxyurea results in increased phosphorylation of H2AX protein CTD PMID:32466334|PMID:32482060 H2ax Rat hydroxyurea multiple interactions ISO H2ax (Mus musculus) 6480464 TRP53 gene mutant form inhibits the reaction [Hydroxyurea results in increased phosphorylation of H2AX protein] CTD PMID:29228353 H2ax Rat hydroxyurea increases phosphorylation ISO H2ax (Mus musculus) 6480464 Hydroxyurea results in increased phosphorylation of H2AX protein CTD PMID:29228353 H2ax Rat IDP multiple interactions ISO H2AX (Homo sapiens) 6480464 Inosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat imiquimod decreases expression ISO H2ax (Mus musculus) 6480464 Imiquimod results in decreased expression of H2AX mRNA CTD PMID:21878529 H2ax Rat indicine increases expression ISO H2AX (Homo sapiens) 6480464 indicine analog results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat inosine multiple interactions ISO H2AX (Homo sapiens) 6480464 Inosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of more ... CTD PMID:32941855 H2ax Rat intermedine increases expression ISO H2AX (Homo sapiens) 6480464 intermedine analog results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat iprodione multiple interactions ISO H2AX (Homo sapiens) 6480464 [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in more ... CTD PMID:22389207|PMID:34503147|PMID:34830855 H2ax Rat irinotecan increases expression ISO H2AX (Homo sapiens) 6480464 Irinotecan metabolite results in increased expression of H2AX mRNA; Irinotecan results in increased expression of more ... CTD PMID:15956246|PMID:30612311 H2ax Rat irinotecan multiple interactions ISO H2AX (Homo sapiens) 6480464 [Irinotecan co-treated with rucaparib] results in increased expression of H2AX protein CTD PMID:30612311 H2ax Rat iron(2+) sulfate (anhydrous) increases expression EXP 6480464 ferrous sulfate results in increased expression of H2AX protein CTD PMID:28583816 H2ax Rat iron(2+) sulfate (anhydrous) multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of H2AX protein] CTD PMID:28583816 H2ax Rat isocyanates increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Isocyanates analog results in increased phosphorylation of H2AX protein CTD PMID:19111005 H2ax Rat isocyanates increases phosphorylation ISO H2ax (Mus musculus) 6480464 [Isocyanates results in increased phosphorylation of ATM protein] which results in increased phosphorylation of H2AX more ... CTD PMID:19197993 H2ax Rat isocyanates increases expression ISO H2AX (Homo sapiens) 6480464 Isocyanates results in increased expression of H2AX protein CTD PMID:19283680 H2ax Rat isoflavones multiple interactions ISO H2AX (Homo sapiens) 6480464 [Isoflavones co-treated with Curcumin] results in increased phosphorylation of H2AX protein CTD PMID:21134073 H2ax Rat isoprenaline increases expression ISO H2ax (Mus musculus) 6480464 Isoproterenol results in increased expression of H2AX mRNA CTD PMID:21335049 H2ax Rat isotretinoin decreases expression ISO H2AX (Homo sapiens) 6480464 Isotretinoin results in decreased expression of H2AX mRNA CTD PMID:20436886 H2ax Rat jacobine increases expression ISO H2AX (Homo sapiens) 6480464 jacobine analog results in increased expression of H2AX protein; jacobine results in increased expression of more ... CTD PMID:31154085 H2ax Rat kaempferol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 kaempferol results in increased phosphorylation of H2AX protein CTD PMID:19028473 H2ax Rat kaempferol increases expression ISO H2AX (Homo sapiens) 6480464 kaempferol results in increased expression of H2AX protein CTD PMID:35063459 H2ax Rat kaempferol increases expression ISO H2ax (Mus musculus) 6480464 kaempferol results in increased expression of H2AX protein CTD PMID:24595819 H2ax Rat L-ascorbic acid multiple interactions ISO H2AX (Homo sapiens) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX more ... CTD PMID:19482829|PMID:26424790 H2ax Rat L-methionine multiple interactions ISO H2ax (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased phosphorylation more ... CTD PMID:20548288 H2ax Rat lapatinib increases expression ISO H2AX (Homo sapiens) 6480464 Lapatinib results in increased expression of H2AX protein CTD PMID:37788138 H2ax Rat lapatinib multiple interactions ISO H2AX (Homo sapiens) 6480464 CYP3A5 protein inhibits the reaction [Lapatinib results in increased expression of H2AX protein]; CYP3A7 protein more ... CTD PMID:37788138 H2ax Rat Lasiocarpine increases phosphorylation EXP 6480464 lasiocarpine results in increased phosphorylation of H2AX protein CTD PMID:31289892 H2ax Rat Lasiocarpine multiple interactions ISO H2AX (Homo sapiens) 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased phosphorylation of H2AX more ... CTD PMID:31103741 H2ax Rat Lasiocarpine increases expression ISO H2AX (Homo sapiens) 6480464 lasiocarpine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat Lasiocarpine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 lasiocarpine results in increased phosphorylation of H2AX protein CTD PMID:31289892 H2ax Rat lead diacetate multiple interactions ISO H2AX (Homo sapiens) 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of H2AX more ... CTD PMID:31874198 H2ax Rat lead(0) multiple interactions ISO H2AX (Homo sapiens) 6480464 [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of H2AX more ... CTD PMID:31874198 H2ax Rat leflunomide decreases expression ISO H2AX (Homo sapiens) 6480464 Leflunomide results in decreased expression of H2AX mRNA CTD PMID:28988120 H2ax Rat leptomycin B multiple interactions ISO H2AX (Homo sapiens) 6480464 leptomycin B promotes the reaction [Bortezomib results in increased expression of H2AX protein modified form] CTD PMID:16778179 H2ax Rat Licochalcone B increases expression ISO H2AX (Homo sapiens) 6480464 licochalcone B results in increased expression of H2AX mRNA CTD PMID:33647349 H2ax Rat Licochalcone B increases phosphorylation ISO H2AX (Homo sapiens) 6480464 licochalcone B results in increased phosphorylation of H2AX protein CTD PMID:35948134 H2ax Rat Liensinine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 liensinine results in increased phosphorylation of H2AX protein CTD PMID:37423554 H2ax Rat Longikaurin A increases expression ISO H2AX (Homo sapiens) 6480464 longikaurin A results in increased expression of H2AX protein modified form CTD PMID:28801140 H2ax Rat lovastatin multiple interactions ISO H2AX (Homo sapiens) 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased phosphorylation of H2AX protein] CTD PMID:21356574 H2ax Rat lovastatin multiple interactions ISO H2ax (Mus musculus) 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form]; Lovastatin more ... CTD PMID:22712078|PMID:26739623|PMID:28710503 H2ax Rat lovastatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form] CTD PMID:26739623 H2ax Rat luteolin multiple interactions ISO H2AX (Homo sapiens) 6480464 CYP1A1 protein promotes the reaction [Luteolin results in increased expression of H2AX protein]; CYP1A2 protein more ... CTD PMID:33727136 H2ax Rat luteolin increases expression ISO H2AX (Homo sapiens) 6480464 Luteolin results in increased expression of H2AX protein CTD PMID:33727136 H2ax Rat LY294002 multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein] CTD PMID:34784199 H2ax Rat magnesium atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated more ... CTD PMID:38605572 H2ax Rat mancozeb multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat maneb multiple interactions ISO H2AX (Homo sapiens) 6480464 [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with more ... CTD PMID:34830855 H2ax Rat manumycin A increases phosphorylation ISO H2AX (Homo sapiens) 6480464 manumycin results in increased phosphorylation of H2AX protein CTD PMID:19409983 H2ax Rat manumycin A multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [manumycin results in increased phosphorylation of H2AX protein] CTD PMID:19409983 H2ax Rat mechlorethamine increases expression ISO H2ax (Mus musculus) 6480464 Mechlorethamine results in increased expression of H2AX protein modified form CTD PMID:25891025 H2ax Rat mechlorethamine increases expression EXP 6480464 Mechlorethamine results in increased expression of H2AX protein modified form CTD PMID:33971176 H2ax Rat MeIQ increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat MeIQx increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat melatonin multiple interactions ISO H2ax (Mus musculus) 6480464 Melatonin inhibits the reaction [[Particulate Matter co-treated with Dietary Fats] results in increased phosphorylation of more ... CTD PMID:35643323|PMID:37994397|PMID:38944328 H2ax Rat melphalan multiple interactions ISO H2AX (Homo sapiens) 6480464 [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Melphalan results in decreased susceptibility to Melphalan]] which results in more ... CTD PMID:25351371 H2ax Rat menadione multiple interactions ISO H2AX (Homo sapiens) 6480464 [Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation more ... CTD PMID:19482829 H2ax Rat menaquinone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Vitamin K 2 results in increased phosphorylation of H2AX protein CTD PMID:29432837 H2ax Rat mestranol decreases expression ISO H2ax (Mus musculus) 6480464 Mestranol results in decreased expression of H2AX mRNA; Mestranol results in decreased expression of H2AX more ... CTD PMID:36098747 H2ax Rat mestranol multiple interactions ISO H2ax (Mus musculus) 6480464 Fulvestrant inhibits the reaction [Mestranol results in decreased expression of H2AX protein] CTD PMID:36098747 H2ax Rat metformin decreases expression ISO H2AX (Homo sapiens) 6480464 Metformin results in decreased expression of H2AX protein CTD PMID:23363784 H2ax Rat metformin increases expression ISO H2AX (Homo sapiens) 6480464 Metformin results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat metformin multiple interactions ISO H2AX (Homo sapiens) 6480464 [epothilone A co-treated with Metformin] results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat methapyrilene increases methylation ISO H2AX (Homo sapiens) 6480464 Methapyrilene results in increased methylation of H2AX polyA tail CTD PMID:30157460 H2ax Rat methotrexate affects response to substance ISO H2AX (Homo sapiens) 6480464 H2AX protein affects the susceptibility to Methotrexate CTD PMID:16217747 H2ax Rat methotrexate increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Methotrexate results in increased phosphorylation of H2AX protein CTD PMID:21114963 H2ax Rat methoxsalen multiple interactions ISO H2AX (Homo sapiens) 6480464 Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein modified form] CTD PMID:23907605 H2ax Rat methoxychlor increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Methoxychlor results in increased phosphorylation of H2AX protein CTD PMID:32466334 H2ax Rat methyl methanesulfonate increases expression ISO H2AX (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of H2AX protein CTD PMID:32087850 H2ax Rat methyl methanesulfonate increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat methyllycaconitine multiple interactions ISO H2AX (Homo sapiens) 6480464 methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein] CTD PMID:34784199 H2ax Rat miconazole increases expression ISO H2ax (Mus musculus) 6480464 Miconazole results in increased expression of H2AX mRNA CTD PMID:27462272 H2ax Rat microcystin-LR increases expression ISO H2AX (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of H2AX protein CTD PMID:36435412 H2ax Rat mitomycin C increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Mitomycin results in increased phosphorylation of H2AX protein CTD PMID:21386838|PMID:32482060|PMID:34510228 H2ax Rat mitomycin C increases expression ISO H2AX (Homo sapiens) 6480464 Mitomycin results in increased expression of H2AX protein; Mitomycin results in increased expression of H2AX more ... CTD PMID:29928969|PMID:32087850 H2ax Rat mitoxantrone increases expression ISO H2AX (Homo sapiens) 6480464 Mitoxantrone results in increased expression of H2AX protein CTD PMID:24994473 H2ax Rat mitoxantrone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Mitoxantrone results in increased phosphorylation of H2AX protein CTD PMID:19738048 H2ax Rat mitoxantrone increases expression EXP 6480464 Mitoxantrone results in increased expression of H2AX protein CTD PMID:29913208 H2ax Rat mitoxantrone multiple interactions EXP 6480464 Poly(ADP-ribose) Polymerase Inhibitors affects the reaction [Mitoxantrone results in increased expression of H2AX protein] CTD PMID:29913208 H2ax Rat MK-2206 multiple interactions ISO H2ax (Mus musculus) 6480464 MK 2206 inhibits the reaction [AKT activator SC79 inhibits the reaction [Dibutyl Phthalate results in more ... CTD PMID:30952838 H2ax Rat ML-792 multiple interactions ISO H2AX (Homo sapiens) 6480464 ML-792 inhibits the reaction [Arsenic results in increased expression of H2AX protein]; ML-792 promotes the more ... CTD PMID:38723480 H2ax Rat mono(2-ethylhexyl) phthalate increases expression ISO H2ax (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of H2AX protein CTD PMID:38563870 H2ax Rat mono(2-ethylhexyl) phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... CTD PMID:39752319 H2ax Rat mono(2-ethylhexyl) phthalate increases phosphorylation ISO H2ax (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased phosphorylation of H2AX protein CTD PMID:36174712 H2ax Rat monobenzyl phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... CTD PMID:39752319 H2ax Rat Monobutylphthalate multiple interactions ISO H2ax (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... CTD PMID:39752319 H2ax Rat monocrotaline increases expression ISO H2AX (Homo sapiens) 6480464 Monocrotaline results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat monoethyl phthalate multiple interactions ISO H2ax (Mus musculus) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-isobutyl more ... CTD PMID:39752319 H2ax Rat monuron increases phosphorylation EXP 6480464 monuron results in increased phosphorylation of H2AX protein CTD PMID:38301995 H2ax Rat MST-312 increases expression ISO H2AX (Homo sapiens) 6480464 MST 312 results in increased expression of H2AX protein modified form CTD PMID:26022559 H2ax Rat myricetin multiple interactions ISO H2AX (Homo sapiens) 6480464 myricetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein] CTD PMID:32107588 H2ax Rat N,N-bis(2-hydroxypropyl)nitrosamine increases phosphorylation EXP 6480464 diisopropanolnitrosamine results in increased phosphorylation of H2AX protein CTD PMID:33211169 H2ax Rat N,N-dimethylformamide increases expression ISO H2AX (Homo sapiens) 6480464 Dimethylformamide results in increased expression of H2AX protein CTD PMID:26387567 H2ax Rat N-acetyl-L-cysteine multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the more ... CTD PMID:15173094|PMID:15489221|PMID:18852132|PMID:19409983|PMID:21135414|PMID:22172632|PMID:23274516|PMID:26148434|PMID:28300663|PMID:28506552|PMID:28993908|PMID:29128613|PMID:29416738|PMID:30408460|PMID:30917517|PMID:31157515|PMID:31168028|PMID:31639374|PMID:31682804|PMID:31715134|PMID:31884112|PMID:32433928|PMID:33971260|PMID:35123993|PMID:35279910|PMID:35326237|PMID:37072049 H2ax Rat N-acetyl-L-cysteine increases expression ISO H2AX (Homo sapiens) 6480464 Acetylcysteine results in increased expression of H2AX protein CTD PMID:31715134|PMID:35123993 H2ax Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ... CTD PMID:26079211|PMID:33031904|PMID:35088107|PMID:36863539 H2ax Rat N-acetyl-L-cysteine multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; more ... CTD PMID:24614525|PMID:25633853|PMID:33961949|PMID:39362619 H2ax Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO H2AX (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of more ... CTD PMID:21227924 H2ax Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde more ... CTD PMID:17875725 H2ax Rat N-butyl-N-(4-hydroxybutyl)nitrosamine increases expression EXP 6480464 Butylhydroxybutylnitrosamine results in increased expression of H2AX protein CTD PMID:26338220|PMID:35771629 H2ax Rat N-ethyl-N-nitrosourea increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Ethylnitrosourea results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat N-methyl-4-phenylpyridinium decreases expression ISO H2AX (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of H2AX mRNA CTD PMID:24810058 H2ax Rat N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO H2AX (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form CTD PMID:26921499|PMID:27233451 H2ax Rat N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO H2ax (Mus musculus) 6480464 Methylnitronitrosoguanidine results in increased expression of H2AX protein CTD PMID:38563870 H2ax Rat N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO H2AX (Homo sapiens) 6480464 [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in more ... CTD PMID:26921499 H2ax Rat N-methyl-N-nitrosourea increases expression ISO H2AX (Homo sapiens) 6480464 Methylnitrosourea results in increased expression of H2AX protein modified form CTD PMID:27233451 H2ax Rat N-nitroso-N-methyl-4-aminobutyric acid multiple interactions ISO H2AX (Homo sapiens) 6480464 [CYP2A6 protein results in increased metabolism of 4-(N-nitroso-N-methylamino)butyric acid] which results in increased expression of more ... CTD PMID:35882637 H2ax Rat N-Nitrosodiethanolamine increases phosphorylation EXP 6480464 N-nitrosodiethanolamine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat N-nitrosodiethylamine increases expression ISO H2ax (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of H2AX protein modified form CTD PMID:27746196 H2ax Rat N-nitrosodiethylamine increases phosphorylation EXP 6480464 Diethylnitrosamine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat N-nitrosodiethylamine multiple interactions ISO H2AX (Homo sapiens) 6480464 [CYP2A6 protein results in increased metabolism of Diethylnitrosamine] which results in increased expression of H2AX more ... CTD PMID:35882637 H2ax Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of H2AX protein CTD PMID:26589970|PMID:37258237 H2ax Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat N-nitrosodimethylamine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Dimethylnitrosamine results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat N-Nitrosomethylethylamine increases phosphorylation EXP 6480464 methylethylnitrosamine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat N-Nitrosopyrrolidine decreases expression ISO H2AX (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of H2AX mRNA CTD PMID:32234424 H2ax Rat N-Phenyl-1-naphthylamine increases expression ISO H2AX (Homo sapiens) 6480464 N-phenyl-1-naphthylamine results in increased expression of H2AX protein CTD PMID:35279910 H2ax Rat n-propyl gallate decreases phosphorylation ISO H2AX (Homo sapiens) 6480464 Propyl Gallate results in decreased phosphorylation of H2AX protein CTD PMID:26928355 H2ax Rat n-propyl gallate multiple interactions ISO H2AX (Homo sapiens) 6480464 [Propyl Gallate results in decreased phosphorylation of H2AX protein] inhibits the reaction [Camptothecin results in more ... CTD PMID:26928355 H2ax Rat nickel atom increases expression ISO H2AX (Homo sapiens) 6480464 Nickel results in increased expression of H2AX mRNA CTD PMID:25583101 H2ax Rat nickel atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated more ... CTD PMID:38605572 H2ax Rat nickel dichloride decreases expression ISO H2AX (Homo sapiens) 6480464 nickel chloride results in decreased expression of H2AX mRNA CTD PMID:17312168 H2ax Rat nickel dichloride increases expression ISO H2AX (Homo sapiens) 6480464 nickel chloride results in increased expression of H2AX protein modified form CTD PMID:28552779 H2ax Rat nickel dichloride increases phosphorylation ISO H2AX (Homo sapiens) 6480464 nickel chloride results in increased phosphorylation of H2AX protein CTD PMID:22172632 H2ax Rat nickel dichloride multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation more ... CTD PMID:22172632 H2ax Rat nicotine multiple interactions ISO H2AX (Homo sapiens) 6480464 Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein modified form] CTD PMID:23907605 H2ax Rat nimesulide multiple interactions ISO H2AX (Homo sapiens) 6480464 nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 H2ax Rat nimustine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Nimustine results in increased phosphorylation of H2AX protein CTD PMID:26418950 H2ax Rat niraparib multiple interactions ISO H2AX (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [niraparib results in increased expression of H2AX protein] CTD PMID:34396909 H2ax Rat niraparib increases expression ISO H2AX (Homo sapiens) 6480464 niraparib results in increased expression of H2AX protein CTD PMID:34396909 H2ax Rat nitenpyram increases expression ISO H2AX (Homo sapiens) 6480464 nitenpyram results in increased expression of H2AX mRNA CTD PMID:35568224 H2ax Rat nitrates multiple interactions ISO H2ax (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of H2AX more ... CTD PMID:35964746 H2ax Rat nitrogen mustard multiple interactions ISO H2AX (Homo sapiens) 6480464 MGMT protein affects the reaction [Nitrogen Mustard Compounds results in increased expression of H2AX protein]; more ... CTD PMID:27342729 H2ax Rat nitrogen mustard increases expression ISO H2AX (Homo sapiens) 6480464 Nitrogen Mustard Compounds results in increased expression of H2AX mRNA; Nitrogen Mustard Compounds results in more ... CTD PMID:27342729 H2ax Rat Nitrosoheptamethyleneimine increases phosphorylation EXP 6480464 N-nitrosoheptamethyleneimine results in increased phosphorylation of H2AX protein CTD PMID:37527026 H2ax Rat NMN zwitterion multiple interactions ISO H2ax (Mus musculus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of H2AX protein] CTD PMID:36756972 H2ax Rat nocodazole increases expression ISO H2AX (Homo sapiens) 6480464 Nocodazole results in increased expression of H2AX protein modified form CTD PMID:26914363 H2ax Rat NORCANTHARIDIN increases expression ISO H2AX (Homo sapiens) 6480464 norcantharidin results in increased expression of H2AX protein modified form CTD PMID:34272796 H2ax Rat NORCANTHARIDIN multiple interactions ISO H2AX (Homo sapiens) 6480464 Paclitaxel promotes the reaction [norcantharidin results in increased expression of H2AX protein modified form] CTD PMID:34272796 H2ax Rat norethisterone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Norethindrone results in increased phosphorylation of H2AX protein CTD PMID:15905198 H2ax Rat NS-398 multiple interactions ISO H2AX (Homo sapiens) 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 H2ax Rat NSC 23766 multiple interactions ISO H2ax (Mus musculus) 6480464 NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of H2AX protein modified form] CTD PMID:28710503 H2ax Rat O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of H2AX protein CTD PMID:26011634 H2ax Rat o-toluidine increases expression ISO H2AX (Homo sapiens) 6480464 2-toluidine results in increased expression of H2AX protein CTD PMID:35279910 H2ax Rat ochratoxin A decreases expression ISO H2AX (Homo sapiens) 6480464 ochratoxin A results in decreased expression of H2AX mRNA CTD PMID:19287073 H2ax Rat ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of H2AX protein CTD PMID:38301995 H2ax Rat ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of H2AX mRNA; ochratoxin A results in increased expression more ... CTD PMID:23358140|PMID:24243707 H2ax Rat ochratoxin A increases expression ISO H2AX (Homo sapiens) 6480464 ochratoxin A results in increased expression of H2AX protein CTD PMID:28286205 H2ax Rat okadaic acid increases expression ISO H2AX (Homo sapiens) 6480464 Okadaic Acid results in increased expression of H2AX mRNA CTD PMID:38832940 H2ax Rat olaparib multiple interactions ISO H2AX (Homo sapiens) 6480464 (+)-JQ1 compound promotes the reaction [olaparib results in increased expression of H2AX protein]; [BRD4 protein more ... CTD PMID:26544897|PMID:29567272 H2ax Rat olaparib increases expression ISO H2AX (Homo sapiens) 6480464 olaparib results in increased expression of H2AX protein CTD PMID:29567272 H2ax Rat olaparib increases phosphorylation ISO H2AX (Homo sapiens) 6480464 olaparib results in increased phosphorylation of H2AX protein CTD PMID:25531448 H2ax Rat otosenine increases expression ISO H2AX (Homo sapiens) 6480464 otosenine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat ouabain increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Ouabain results in increased phosphorylation of H2AX protein CTD PMID:31436044 H2ax Rat oxaliplatin increases expression ISO H2AX (Homo sapiens) 6480464 Oxaliplatin results in increased expression of H2AX protein modified form CTD PMID:19735649 H2ax Rat oxaliplatin multiple interactions EXP 6480464 [Oxaliplatin co-treated with Topotecan] results in decreased expression of H2AX mRNA CTD PMID:25729387 H2ax Rat oxaliplatin affects localization ISO H2AX (Homo sapiens) 6480464 Oxaliplatin affects the localization of H2AX protein modified form CTD PMID:19735649 H2ax Rat oxaliplatin multiple interactions ISO H2AX (Homo sapiens) 6480464 [pifithrin results in decreased phosphorylation of TP53 protein] inhibits the reaction [Oxaliplatin results in increased more ... CTD PMID:19735649|PMID:21285347|PMID:21750216|PMID:33271260 H2ax Rat oxybenzone increases expression ISO H2AX (Homo sapiens) 6480464 oxybenzone results in increased expression of H2AX protein modified form CTD PMID:31939680 H2ax Rat oxybenzone increases expression ISO H2ax (Mus musculus) 6480464 oxybenzone results in increased expression of H2AX protein modified form CTD PMID:31939680 H2ax Rat oxybenzone multiple interactions ISO H2AX (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [oxybenzone results in increased expression of H2AX protein modified form] CTD PMID:31939680 H2ax Rat ozone multiple interactions ISO H2ax (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... CTD PMID:34911549 H2ax Rat ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Ozone]] which results in more ... CTD PMID:36423397 H2ax Rat p-tert-Amylphenol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of H2AX protein CTD PMID:32466334 H2ax Rat paclitaxel increases expression ISO H2AX (Homo sapiens) 6480464 Paclitaxel results in increased expression of H2AX protein; Paclitaxel results in increased expression of H2AX more ... CTD PMID:18451153|PMID:22302033|PMID:34272796 H2ax Rat paclitaxel multiple interactions ISO H2AX (Homo sapiens) 6480464 Paclitaxel promotes the reaction [norcantharidin results in increased expression of H2AX protein modified form]; palbociclib more ... CTD PMID:22302033|PMID:34272796 H2ax Rat palbociclib multiple interactions ISO H2AX (Homo sapiens) 6480464 Doxorubicin inhibits the reaction [palbociclib results in decreased phosphorylation of H2AX protein]; palbociclib inhibits the more ... CTD PMID:22302033|PMID:22751436 H2ax Rat palbociclib decreases phosphorylation ISO H2AX (Homo sapiens) 6480464 palbociclib results in decreased phosphorylation of H2AX protein CTD PMID:22751436 H2ax Rat palmatine increases expression ISO H2AX (Homo sapiens) 6480464 palmatine results in increased expression of H2AX protein modified form CTD PMID:23747414 H2ax Rat panobinostat increases expression ISO H2AX (Homo sapiens) 6480464 Panobinostat results in increased expression of H2AX protein CTD PMID:22923501 H2ax Rat panobinostat multiple interactions ISO H2AX (Homo sapiens) 6480464 manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Resveratrol promotes the reaction [Panobinostat results in increased expression of more ... CTD PMID:22923501|PMID:23681230 H2ax Rat paracetamol increases expression ISO H2AX (Homo sapiens) 6480464 Acetaminophen results in increased expression of H2AX mRNA; Acetaminophen results in increased expression of H2AX more ... CTD PMID:21420995|PMID:22230336|PMID:33971260 H2ax Rat paracetamol multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide promotes the reaction [Acetaminophen results in increased expression of H2AX protein]; Acetylcysteine inhibits the more ... CTD PMID:33971260 H2ax Rat paracetamol increases expression ISO H2ax (Mus musculus) 6480464 Acetaminophen results in increased expression of H2AX protein modified form CTD PMID:29540258 H2ax Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of H2AX mRNA; Acetaminophen results in decreased expression of H2AX more ... CTD PMID:26011634|PMID:33387578 H2ax Rat paracetamol affects expression ISO H2ax (Mus musculus) 6480464 Acetaminophen affects the expression of H2AX mRNA CTD PMID:17562736 H2ax Rat paracetamol affects expression ISO H2AX (Homo sapiens) 6480464 Acetaminophen affects the expression of H2AX mRNA CTD PMID:25458485 H2ax Rat paraquat increases expression ISO H2ax (Mus musculus) 6480464 Paraquat results in increased expression of H2AX protein CTD PMID:28012437|PMID:34811946 H2ax Rat paraquat multiple interactions ISO H2ax (Mus musculus) 6480464 ATG7 protein affects the reaction [Paraquat results in increased expression of H2AX protein]; ST2825 inhibits more ... CTD PMID:28012437|PMID:34811946 H2ax Rat pectolinarigenin increases expression ISO H2AX (Homo sapiens) 6480464 pectolinarigenin results in increased expression of H2AX protein CTD PMID:37393350 H2ax Rat pectolinarigenin multiple interactions ISO H2AX (Homo sapiens) 6480464 TOP2A protein affects the reaction [pectolinarigenin results in increased expression of H2AX protein] CTD PMID:37393350 H2ax Rat pentachlorophenol increases expression ISO H2ax (Mus musculus) 6480464 Pentachlorophenol results in increased expression of H2AX mRNA CTD PMID:23892564 H2ax Rat pentamidine affects localization ISO H2AX (Homo sapiens) 6480464 Pentamidine affects the localization of H2AX protein modified form CTD PMID:20144237 H2ax Rat perfluorooctane-1-sulfonic acid multiple interactions ISO H2ax (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of H2AX mRNA CTD PMID:36331819 H2ax Rat Phellopterin multiple interactions ISO H2AX (Homo sapiens) 6480464 phellopterin promotes the reaction [[Carboplatin results in increased phosphorylation of H2AX protein] which results in more ... CTD PMID:37708916 H2ax Rat phenanthridone increases expression ISO H2AX (Homo sapiens) 6480464 phenanthridone results in increased expression of H2AX protein modified form CTD PMID:29416738 H2ax Rat phenanthridone multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [phenanthridone results in increased expression of H2AX protein modified form]; TXNRD1 more ... CTD PMID:29416738 H2ax Rat phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of H2AX mRNA CTD PMID:31324951 H2ax Rat phenobarbital affects expression ISO H2AX (Homo sapiens) 6480464 Phenobarbital affects the expression of H2AX mRNA CTD PMID:19159669 H2ax Rat phenobarbital increases expression ISO H2ax (Mus musculus) 6480464 Phenobarbital results in increased expression of H2AX mRNA CTD PMID:19363144|PMID:23091169 H2ax Rat phenol affects localization ISO H2AX (Homo sapiens) 6480464 Phenol affects the localization of H2AX protein modified form CTD PMID:20096274 H2ax Rat PhIP increases expression ISO H2AX (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of H2AX protein modified form CTD PMID:28160022 H2ax Rat PhIP increases phosphorylation ISO H2AX (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased phosphorylation of H2AX protein CTD PMID:32466334|PMID:34510228 H2ax Rat phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of H2AX protein CTD PMID:21439308 H2ax Rat phosphoramide mustard multiple interactions EXP 6480464 phosphoramide mustard results in increased phosphorylation of and results in increased expression of H2AX protein CTD PMID:25497287 H2ax Rat phosphoramide mustard increases expression ISO H2ax (Mus musculus) 6480464 phosphoramide mustard results in increased expression of H2AX protein CTD PMID:21439308 H2ax Rat phthalic acid multiple interactions ISO H2AX (Homo sapiens) 6480464 [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased expression of H2AX more ... CTD PMID:22659117 H2ax Rat pifithrin-alpha hydrobromide multiple interactions ISO H2AX (Homo sapiens) 6480464 [pifithrin results in decreased phosphorylation of TP53 protein] inhibits the reaction [Oxaliplatin results in increased more ... CTD PMID:19732952|PMID:19735649|PMID:25448276|PMID:26259609 H2ax Rat pifithrin-alpha hydrobromide multiple interactions ISO H2ax (Mus musculus) 6480464 pifithrin promotes the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; more ... CTD PMID:33961949 H2ax Rat pinocembrin multiple interactions ISO H2AX (Homo sapiens) 6480464 pinocembrin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of H2AX protein] CTD PMID:33393179 H2ax Rat pinocembrin multiple interactions ISO H2ax (Mus musculus) 6480464 pinocembrin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of H2AX protein] CTD PMID:33393179 H2ax Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of H2AX mRNA CTD PMID:15890375 H2ax Rat pirinixic acid decreases expression ISO H2ax (Mus musculus) 6480464 pirinixic acid results in decreased expression of H2AX mRNA CTD PMID:17426115 H2ax Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of H2AX mRNA CTD PMID:15890375|PMID:19162173 H2ax Rat piroxicam decreases expression ISO H2AX (Homo sapiens) 6480464 Piroxicam results in decreased expression of H2AX mRNA CTD PMID:21858171 H2ax Rat poly(vinylpyrrolidone) multiple interactions ISO H2AX (Homo sapiens) 6480464 [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 H2ax Rat potassium bromate multiple interactions EXP 6480464 Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]; trichostatin A more ... CTD PMID:25015661 H2ax Rat potassium bromate multiple interactions ISO H2ax (Mus musculus) 6480464 [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased more ... CTD PMID:25693136 H2ax Rat potassium bromate increases phosphorylation EXP 6480464 potassium bromate results in increased phosphorylation of H2AX protein CTD PMID:25015661 H2ax Rat potassium dichromate multiple interactions ISO H2AX (Homo sapiens) 6480464 EHMT2 protein promotes the reaction [Potassium Dichromate results in increased expression of H2AX protein modified more ... CTD PMID:29391238 H2ax Rat potassium dichromate increases expression ISO H2AX (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of H2AX protein modified form CTD PMID:29391238 H2ax Rat Pranoprofen increases expression ISO H2AX (Homo sapiens) 6480464 pyranoprofen results in increased expression of H2AX protein CTD PMID:31765691 H2ax Rat procymidone multiple interactions ISO H2AX (Homo sapiens) 6480464 [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in more ... CTD PMID:22389207|PMID:34503147 H2ax Rat promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of H2AX protein CTD PMID:26011634 H2ax Rat propiconazole increases expression ISO H2ax (Mus musculus) 6480464 propiconazole results in increased expression of H2AX mRNA CTD PMID:19363144|PMID:21278054 H2ax Rat propylparaben multiple interactions ISO H2AX (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [propylparaben results in increased expression of H2AX protein modified form] CTD PMID:31939680 H2ax Rat propylparaben increases expression ISO H2AX (Homo sapiens) 6480464 propylparaben results in increased expression of H2AX protein modified form CTD PMID:31939680 H2ax Rat protein kinase inhibitor increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Protein Kinase Inhibitors results in increased phosphorylation of H2AX protein CTD PMID:21878655 H2ax Rat pterostilbene multiple interactions ISO H2AX (Homo sapiens) 6480464 [Resveratrol co-treated with pterostilbene] results in decreased expression of H2AX protein modified form; CCN1 protein more ... CTD PMID:26459286|PMID:34405320 H2ax Rat pterostilbene multiple interactions ISO H2ax (Mus musculus) 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of more ... CTD PMID:34405320 H2ax Rat pyrene multiple interactions ISO H2AX (Homo sapiens) 6480464 [pyrene co-treated with Benzo(a)pyrene] results in increased expression of H2AX protein; [pyrene co-treated with fluoranthene more ... CTD PMID:33249052 H2ax Rat pyrimethamine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Pyrimethamine results in increased phosphorylation of H2AX protein CTD PMID:19435820 H2ax Rat pyrrolidine dithiocarbamate multiple interactions ISO H2AX (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in more ... CTD PMID:36997055 H2ax Rat quercetin multiple interactions ISO H2AX (Homo sapiens) 6480464 Quercetin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form] CTD PMID:24999622 H2ax Rat quercetin increases expression ISO H2ax (Mus musculus) 6480464 Quercetin results in increased expression of H2AX protein CTD PMID:24595819 H2ax Rat quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein modified form] CTD PMID:24902966 H2ax Rat quercetin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Quercetin results in increased phosphorylation of H2AX protein CTD PMID:15177039 H2ax Rat quizartinib increases phosphorylation ISO H2AX (Homo sapiens) 6480464 quizartinib results in increased phosphorylation of H2AX protein CTD PMID:34665271 H2ax Rat quizartinib multiple interactions ISO H2AX (Homo sapiens) 6480464 quizartinib affects the reaction [RGFP966 results in increased phosphorylation of H2AX protein]; quizartinib promotes the more ... CTD PMID:34665271 H2ax Rat rac-1,2-dichloropropane increases phosphorylation ISO H2AX (Homo sapiens) 6480464 propylene dichloride results in increased phosphorylation of H2AX protein CTD PMID:28300663 H2ax Rat rac-1,2-dichloropropane multiple interactions ISO H2ax (Mus musculus) 6480464 NFE2L2 gene mutant form inhibits the reaction [propylene dichloride results in increased expression of H2AX more ... CTD PMID:37326970 H2ax Rat rac-1,2-dichloropropane increases phosphorylation ISO H2ax (Mus musculus) 6480464 propylene dichloride results in increased phosphorylation of H2AX protein CTD PMID:28300663 H2ax Rat rac-1,2-dichloropropane multiple interactions ISO H2AX (Homo sapiens) 6480464 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits more ... CTD PMID:28300663 H2ax Rat razoxane multiple interactions EXP 6480464 Razoxane inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; Razoxane inhibits the more ... CTD PMID:17875725 H2ax Rat reactive oxygen species decreases response to substance ISO H2ax (Mus musculus) 6480464 H2AX protein results in decreased susceptibility to Reactive Oxygen Species CTD PMID:21555580 H2ax Rat remdesivir increases expression ISO H2AX (Homo sapiens) 6480464 remdesivir results in increased expression of H2AX protein CTD PMID:35417658 H2ax Rat resorcinol increases expression ISO H2AX (Homo sapiens) 6480464 resorcinol results in increased expression of H2AX mRNA CTD PMID:22623647 H2ax Rat resveratrol multiple interactions ISO H2AX (Homo sapiens) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Resveratrol results in increased phosphorylation of H2AX protein]; [Coumestrol co-treated with more ... CTD PMID:15975956|PMID:19167446|PMID:22923501|PMID:23522185|PMID:25619392|PMID:25895606|PMID:26459286 H2ax Rat resveratrol multiple interactions ISO H2ax (Mus musculus) 6480464 Resveratrol inhibits the reaction [bisphenol A promotes the reaction [Cholesterol results in increased phosphorylation of more ... CTD PMID:33239236 H2ax Rat resveratrol decreases expression ISO H2AX (Homo sapiens) 6480464 Resveratrol results in decreased expression of H2AX protein; Resveratrol results in decreased expression of H2AX more ... CTD PMID:23363784|PMID:26459286 H2ax Rat resveratrol increases response to substance ISO H2AX (Homo sapiens) 6480464 H2AX protein results in increased susceptibility to Resveratrol CTD PMID:25619392 H2ax Rat resveratrol increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Resveratrol results in increased phosphorylation of H2AX protein CTD PMID:15975956|PMID:19559722|PMID:20697895|PMID:23522185|PMID:25619392 H2ax Rat resveratrol increases expression ISO H2AX (Homo sapiens) 6480464 Resveratrol results in increased expression of H2AX protein; Resveratrol results in increased expression of H2AX more ... CTD PMID:22923501|PMID:23681230|PMID:25895606 H2ax Rat Retrorsine increases expression ISO H2AX (Homo sapiens) 6480464 retrorsine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat RGFP966 increases phosphorylation ISO H2AX (Homo sapiens) 6480464 RGFP966 results in increased phosphorylation of H2AX protein CTD PMID:34665271 H2ax Rat RGFP966 multiple interactions ISO H2AX (Homo sapiens) 6480464 quizartinib affects the reaction [RGFP966 results in increased phosphorylation of H2AX protein]; RGFP966 affects the more ... CTD PMID:34665271 H2ax Rat ribavirin increases expression ISO H2AX (Homo sapiens) 6480464 Ribavirin results in increased expression of H2AX protein modified form CTD PMID:32112805 H2ax Rat riddelliine increases expression ISO H2AX (Homo sapiens) 6480464 riddelliine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat riddelliine increases phosphorylation EXP 6480464 riddelliine results in increased phosphorylation of H2AX protein CTD PMID:31289892 H2ax Rat riddelliine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 riddelliine results in increased phosphorylation of H2AX protein CTD PMID:31289892 H2ax Rat romidepsin multiple interactions ISO H2AX (Homo sapiens) 6480464 [Bortezomib co-treated with romidepsin] results in increased phosphorylation of H2AX protein; Acetylcysteine inhibits the reaction more ... CTD PMID:15173094|PMID:34665271 H2ax Rat romidepsin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 romidepsin results in increased phosphorylation of H2AX protein CTD PMID:34665271 H2ax Rat rotenone increases phosphorylation ISO H2ax (Mus musculus) 6480464 Rotenone results in increased phosphorylation of H2AX protein CTD PMID:23619996 H2ax Rat rotenone multiple interactions ISO H2AX (Homo sapiens) 6480464 [PSME4 protein affects the susceptibility to Rotenone] which results in decreased expression of H2AX protein more ... CTD PMID:32368861 H2ax Rat rotenone multiple interactions ISO H2ax (Mus musculus) 6480464 CASP1 gene mutant form inhibits the reaction [Rotenone results in increased phosphorylation of H2AX protein]; more ... CTD PMID:23619996 H2ax Rat rotenone decreases response to substance ISO H2ax (Mus musculus) 6480464 H2AX protein results in decreased susceptibility to Rotenone CTD PMID:21555580 H2ax Rat rubimaillin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 rubimaillin results in increased phosphorylation of H2AX protein CTD PMID:35007525 H2ax Rat rubimaillin multiple interactions ISO H2AX (Homo sapiens) 6480464 Glutathione inhibits the reaction [rubimaillin results in increased phosphorylation of H2AX protein] CTD PMID:35007525 H2ax Rat rubimaillin increases phosphorylation ISO H2ax (Mus musculus) 6480464 rubimaillin results in increased phosphorylation of H2AX protein CTD PMID:35007525 H2ax Rat rucaparib multiple interactions ISO H2AX (Homo sapiens) 6480464 [Irinotecan co-treated with rucaparib] results in increased expression of H2AX protein; [rucaparib co-treated with CPI-0610] more ... CTD PMID:30612311|PMID:32927276 H2ax Rat rucaparib affects expression ISO H2AX (Homo sapiens) 6480464 rucaparib affects the expression of H2AX protein CTD PMID:30612311 H2ax Rat ruxolitinib multiple interactions ISO H2AX (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with ruxolitinib] results in increased phosphorylation of H2AX protein CTD PMID:30012499 H2ax Rat Salinomycin decreases expression ISO H2AX (Homo sapiens) 6480464 salinomycin results in decreased expression of H2AX mRNA CTD PMID:35914560 H2ax Rat Salinomycin multiple interactions ISO H2AX (Homo sapiens) 6480464 [salinomycin co-treated with Calcitriol] results in decreased expression of H2AX mRNA CTD PMID:35914560 H2ax Rat Satratoxin H increases phosphorylation EXP 6480464 satratoxin H results in increased phosphorylation of H2AX protein CTD PMID:22863859 H2ax Rat SB 431542 multiple interactions ISO H2AX (Homo sapiens) 6480464 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in more ... CTD PMID:30804470 H2ax Rat selenium atom increases expression ISO H2AX (Homo sapiens) 6480464 Selenium results in increased expression of H2AX mRNA CTD PMID:19244175 H2ax Rat selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Acrylamide results in increased expression of H2AX protein] CTD PMID:37987225 H2ax Rat selenocystine multiple interactions ISO H2AX (Homo sapiens) 6480464 [selenocystine co-treated with Cisplatin] results in increased expression of H2AX protein; Cisplatin promotes the reaction more ... CTD PMID:39461470 H2ax Rat selenocystine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 selenocystine results in increased phosphorylation of H2AX protein CTD PMID:35863474 H2ax Rat selenocystine increases phosphorylation ISO H2ax (Mus musculus) 6480464 selenocystine results in increased phosphorylation of H2AX protein CTD PMID:35863474 H2ax Rat selenocystine increases expression ISO H2AX (Homo sapiens) 6480464 selenocystine results in increased expression of H2AX protein CTD PMID:39461470 H2ax Rat selinexor increases expression ISO H2AX (Homo sapiens) 6480464 selinexor results in increased expression of H2AX protein CTD PMID:37899423 H2ax Rat selinexor multiple interactions ISO H2AX (Homo sapiens) 6480464 [selinexor co-treated with INCB057643] results in increased expression of H2AX protein CTD PMID:37899423 H2ax Rat senecionine increases expression ISO H2AX (Homo sapiens) 6480464 senecionine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat seneciphylline increases expression ISO H2AX (Homo sapiens) 6480464 seneciphylline results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat Senkirkine increases expression ISO H2AX (Homo sapiens) 6480464 senkirkine results in increased expression of H2AX protein CTD PMID:31154085 H2ax Rat serpentine asbestos affects expression ISO H2AX (Homo sapiens) 6480464 Asbestos, Serpentine affects the expression of H2AX protein CTD PMID:38301883 H2ax Rat serpentine asbestos multiple interactions ISO H2AX (Homo sapiens) 6480464 [Asbestos, Serpentine results in increased abundance of [Magnesium co-treated with Chromium co-treated with Nickel co-treated more ... CTD PMID:38605572 H2ax Rat silibinin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Silybin results in increased phosphorylation of H2AX protein CTD PMID:16777994 H2ax Rat silibinin multiple interactions ISO H2AX (Homo sapiens) 6480464 Caffeine inhibits the reaction [Silybin results in increased phosphorylation of H2AX protein] CTD PMID:16777994 H2ax Rat silicon dioxide increases expression ISO H2AX (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of H2AX mRNA; Silicon Dioxide results in increased expression more ... CTD PMID:25351596|PMID:28757444 H2ax Rat silicon dioxide increases expression ISO H2ax (Mus musculus) 6480464 Silicon Dioxide results in increased expression of H2AX mRNA; Silicon Dioxide results in increased expression more ... CTD PMID:29341224|PMID:39362619 H2ax Rat silicon dioxide multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of H2AX mRNA]; Acetylcysteine inhibits more ... CTD PMID:39362619 H2ax Rat silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide results in increased phosphorylation of H2AX protein CTD PMID:23178243 H2ax Rat silicon dioxide increases phosphorylation ISO H2ax (Mus musculus) 6480464 Silicon Dioxide results in increased phosphorylation of H2AX protein CTD PMID:23619996 H2ax Rat silicon dioxide multiple interactions ISO H2AX (Homo sapiens) 6480464 PARP1 protein inhibits the reaction [Silicon Dioxide results in increased expression of H2AX protein modified more ... CTD PMID:28757444 H2ax Rat silver atom multiple interactions ISO H2AX (Homo sapiens) 6480464 [Silver analog co-treated with poly(N-vinylpyrrolidine)] results in increased expression of H2AX protein; [Silver co-treated with more ... CTD PMID:26028148|PMID:27387714 H2ax Rat silver(0) multiple interactions ISO H2AX (Homo sapiens) 6480464 [Silver analog co-treated with poly(N-vinylpyrrolidine)] results in increased expression of H2AX protein; [Silver co-treated with more ... CTD PMID:26028148|PMID:27387714 H2ax Rat simvastatin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Simvastatin results in increased phosphorylation of H2AX protein CTD PMID:20499237 H2ax Rat sirolimus decreases expression ISO H2AX (Homo sapiens) 6480464 Sirolimus results in decreased expression of H2AX protein CTD PMID:23363784 H2ax Rat sodium arsenite increases expression ISO H2AX (Homo sapiens) 6480464 sodium arsenite results in increased expression of H2AX mRNA; sodium arsenite results in increased expression more ... CTD PMID:22706169|PMID:24866292|PMID:28595984|PMID:29161537|PMID:29301061|PMID:32844245|PMID:32866568|PMID:34032870|PMID:36089002|PMID:36958258|PMID:38228842|PMID:38678786|PMID:39756915 H2ax Rat sodium arsenite multiple interactions ISO H2AX (Homo sapiens) 6480464 ATG5 protein affects the reaction [sodium arsenite results in increased expression of H2AX protein]; bafilomycin more ... CTD PMID:38678786|PMID:39265400 H2ax Rat sodium arsenite decreases expression ISO H2AX (Homo sapiens) 6480464 sodium arsenite results in decreased expression of H2AX mRNA CTD PMID:38568856 H2ax Rat sodium arsenite multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in more ... CTD PMID:31542844 H2ax Rat sodium arsenite decreases expression ISO H2ax (Mus musculus) 6480464 sodium arsenite results in decreased expression of H2AX mRNA CTD PMID:16014739 H2ax Rat sodium arsenite increases phosphorylation ISO H2ax (Mus musculus) 6480464 sodium arsenite results in increased phosphorylation of H2AX protein CTD PMID:30456849|PMID:39265400 H2ax Rat sodium arsenite increases expression ISO H2ax (Mus musculus) 6480464 sodium arsenite results in increased expression of H2AX protein modified form CTD PMID:25787150 H2ax Rat sodium arsenite increases phosphorylation ISO H2AX (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of H2AX protein CTD PMID:20375080|PMID:29039521|PMID:34510228|PMID:39265400 H2ax Rat sodium chromate multiple interactions ISO H2AX (Homo sapiens) 6480464 MUS81 protein mutant form inhibits the reaction [sodium chromate(VI) results in increased expression of H2AX more ... CTD PMID:28318385 H2ax Rat sodium chromate multiple interactions ISO H2ax (Mus musculus) 6480464 [sodium chromate(VI) results in increased abundance of chromium hexavalent ion] which results in increased expression more ... CTD PMID:35643323 H2ax Rat sodium chromate increases expression ISO H2AX (Homo sapiens) 6480464 sodium chromate(VI) results in increased expression of H2AX protein modified form CTD PMID:28318385 H2ax Rat sodium dichromate decreases expression ISO H2ax (Mus musculus) 6480464 sodium bichromate results in decreased expression of H2AX mRNA CTD PMID:31558096 H2ax Rat sodium fluoride decreases expression ISO H2ax (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of H2AX protein CTD PMID:28918527 H2ax Rat sodium fluoride increases expression ISO H2ax (Mus musculus) 6480464 Sodium Fluoride results in increased expression of H2AX protein CTD PMID:27548804 H2ax Rat sodium nitrite increases expression ISO H2ax (Mus musculus) 6480464 Sodium Nitrite results in increased expression of H2AX protein modified form CTD PMID:31476334 H2ax Rat Sodium salicylate increases expression ISO H2AX (Homo sapiens) 6480464 Sodium Salicylate results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat sorafenib increases expression ISO H2ax (Mus musculus) 6480464 Sorafenib results in increased expression of H2AX protein CTD PMID:38884142 H2ax Rat sorafenib multiple interactions ISO H2ax (Mus musculus) 6480464 empagliflozin inhibits the reaction [Sorafenib results in increased expression of H2AX protein] CTD PMID:38884142 H2ax Rat sterigmatocystin increases expression ISO H2AX (Homo sapiens) 6480464 Sterigmatocystin results in increased expression of H2AX protein modified form CTD PMID:26914363 H2ax Rat sulindac multiple interactions ISO H2AX (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Sulindac] results in increased phosphorylation of H2AX protein CTD PMID:18636201 H2ax Rat sunitinib decreases expression ISO H2AX (Homo sapiens) 6480464 Sunitinib results in decreased expression of H2AX mRNA CTD PMID:31533062 H2ax Rat T-2 toxin multiple interactions ISO H2AX (Homo sapiens) 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein] CTD PMID:20150440 H2ax Rat T-2 toxin increases activity ISO H2AX (Homo sapiens) 6480464 T-2 Toxin results in increased activity of H2AX protein CTD PMID:20150440 H2ax Rat Tartrolon D increases expression ISO H2ax (Mus musculus) 6480464 tartrolon D results in increased expression of H2AX protein CTD PMID:39097071 H2ax Rat Tartrolon D increases expression ISO H2AX (Homo sapiens) 6480464 tartrolon D results in increased expression of H2AX protein CTD PMID:39097071 H2ax Rat temozolomide multiple interactions ISO H2AX (Homo sapiens) 6480464 [Temozolomide co-treated with Resveratrol] results in increased phosphorylation of H2AX protein CTD PMID:23522185 H2ax Rat temozolomide decreases response to substance ISO H2ax (Mus musculus) 6480464 H2AX protein results in decreased susceptibility to Temozolomide CTD PMID:21555580 H2ax Rat temozolomide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Temozolomide results in increased phosphorylation of H2AX protein CTD PMID:23522185|PMID:26418950 H2ax Rat TEMPO increases expression ISO H2ax (Mus musculus) 6480464 TEMPO results in increased expression of H2AX protein CTD PMID:25882087 H2ax Rat terbufos increases expression ISO H2AX (Homo sapiens) 6480464 terbufos results in increased expression of H2AX protein CTD PMID:33221015 H2ax Rat tert-butyl hydroperoxide decreases expression ISO H2AX (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of H2AX mRNA CTD PMID:15336504 H2ax Rat tert-butyl hydroperoxide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased phosphorylation of H2AX protein CTD PMID:33207735 H2ax Rat testosterone multiple interactions ISO H2AX (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of H2AX mRNA CTD PMID:21592394 H2ax Rat testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of H2AX mRNA CTD PMID:26496021 H2ax Rat testosterone decreases expression ISO H2AX (Homo sapiens) 6480464 Testosterone results in decreased expression of H2AX mRNA CTD PMID:21592394 H2ax Rat tetrachloromethane increases expression ISO H2ax (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of H2AX mRNA CTD PMID:31919559 H2ax Rat tetrachloromethane increases phosphorylation ISO H2ax (Mus musculus) 6480464 Carbon Tetrachloride results in increased phosphorylation of H2AX protein CTD PMID:36526012 H2ax Rat tetrachloromethane multiple interactions ISO H2ax (Mus musculus) 6480464 ATM protein inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of H2AX protein] CTD PMID:36526012 H2ax Rat tetramethylpyrazine multiple interactions ISO H2AX (Homo sapiens) 6480464 [tetramethylpyrazine co-treated with evodiamine] results in increased expression of H2AX protein CTD PMID:39486648 H2ax Rat tetraphene increases expression ISO H2AX (Homo sapiens) 6480464 benz(a)anthracene metabolite results in increased expression of H2AX protein CTD PMID:31051210 H2ax Rat thallium(I) acetate increases expression ISO H2AX (Homo sapiens) 6480464 thallium acetate results in increased expression of H2AX protein CTD PMID:36745568 H2ax Rat thapsigargin increases expression ISO H2AX (Homo sapiens) 6480464 Thapsigargin results in increased expression of H2AX mRNA CTD PMID:19442820 H2ax Rat thapsigargin decreases phosphorylation ISO H2AX (Homo sapiens) 6480464 Thapsigargin results in decreased phosphorylation of H2AX protein CTD PMID:32482060 H2ax Rat Theaflavin 3,3'-digallate decreases expression ISO H2AX (Homo sapiens) 6480464 theaflavin-3,3'-digallate results in decreased expression of H2AX protein CTD PMID:34925699 H2ax Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of H2AX mRNA; Thioacetamide results in increased expression of H2AX more ... CTD PMID:26011634|PMID:34492290|PMID:37258237 H2ax Rat thiram decreases expression ISO H2AX (Homo sapiens) 6480464 Thiram results in decreased expression of H2AX mRNA CTD PMID:38568856 H2ax Rat thymidine multiple interactions ISO H2AX (Homo sapiens) 6480464 Thymidine inhibits the reaction [PIF1 protein inhibits the reaction [Gemcitabine results in increased expression of more ... CTD PMID:37183367 H2ax Rat thymoquinone increases phosphorylation ISO H2AX (Homo sapiens) 6480464 thymoquinone results in increased phosphorylation of H2AX protein CTD PMID:31298468 H2ax Rat Tiron increases phosphorylation ISO H2AX (Homo sapiens) 6480464 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt results in increased phosphorylation of H2AX protein CTD PMID:22785532 H2ax Rat Tiron multiple interactions ISO H2AX (Homo sapiens) 6480464 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [9-bromo-5-(4,5-dimethoxy-1,3-dihydroisobenzofuran-1-yl)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-(1,3)-dioxolo(4,5-g)isoquinoline results in increased phosphorylation of H2AX protein] CTD PMID:22785532 H2ax Rat titanium dioxide increases expression ISO H2ax (Mus musculus) 6480464 titanium dioxide results in increased expression of H2AX mRNA CTD PMID:23557971 H2ax Rat Tomentosin increases expression ISO H2AX (Homo sapiens) 6480464 tomentosin results in increased expression of H2AX protein CTD PMID:30917517 H2ax Rat Tomentosin increases phosphorylation ISO H2AX (Homo sapiens) 6480464 tomentosin results in increased phosphorylation of H2AX protein CTD PMID:27922187 H2ax Rat Tomentosin multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [tomentosin results in increased expression of H2AX protein] CTD PMID:30917517 H2ax Rat topotecan increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Topotecan results in increased phosphorylation of H2AX protein CTD PMID:16432175 H2ax Rat topotecan increases expression ISO H2AX (Homo sapiens) 6480464 Topotecan results in increased expression of H2AX protein modified form CTD PMID:23376119 H2ax Rat topotecan multiple interactions ISO H2ax (Mus musculus) 6480464 APAF1 promotes the reaction [Topotecan results in increased phosphorylation of H2AX protein]; TRP53 inhibits the more ... CTD PMID:19812371 H2ax Rat topotecan increases phosphorylation ISO H2ax (Mus musculus) 6480464 Topotecan results in increased phosphorylation of H2AX protein CTD PMID:19812371 H2ax Rat topotecan multiple interactions EXP 6480464 [Oxaliplatin co-treated with Topotecan] results in decreased expression of H2AX mRNA CTD PMID:25729387 H2ax Rat topotecan multiple interactions ISO H2AX (Homo sapiens) 6480464 [veliparib co-treated with Topotecan] results in increased expression of H2AX protein CTD PMID:21795476 H2ax Rat toxaphene decreases expression EXP 6480464 Toxaphene results in decreased expression of H2AX mRNA CTD PMID:23153324 H2ax Rat triadimefon increases expression ISO H2ax (Mus musculus) 6480464 triadimefon results in increased expression of H2AX mRNA CTD PMID:19363144 H2ax Rat triapine increases expression ISO H2AX (Homo sapiens) 6480464 3-aminopyridine-2-carboxaldehyde thiosemicarbazone results in increased expression of H2AX protein CTD PMID:25130544 H2ax Rat tributylstannane multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Phycocyanin more ... CTD PMID:26079211 H2ax Rat tributylstannane increases expression ISO H2AX (Homo sapiens) 6480464 tributyltin results in increased expression of H2AX protein modified form CTD PMID:31401084 H2ax Rat tributylstannane increases phosphorylation ISO H2AX (Homo sapiens) 6480464 tributyltin results in increased phosphorylation of H2AX protein CTD PMID:36319700 H2ax Rat tributylstannane increases phosphorylation ISO H2ax (Mus musculus) 6480464 tributyltin results in increased phosphorylation of H2AX protein CTD PMID:36319700 H2ax Rat tributylstannane multiple interactions ISO H2AX (Homo sapiens) 6480464 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased phosphorylation of H2AX protein]; DFFB protein promotes more ... CTD PMID:31401084|PMID:36319700 H2ax Rat tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of H2AX protein modified form CTD PMID:26079211 H2ax Rat trichloroethene multiple interactions ISO H2AX (Homo sapiens) 6480464 1-aminobenzotriazole inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the more ... CTD PMID:29722447 H2ax Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of H2AX mRNA CTD PMID:33387578 H2ax Rat trichloroethene increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Trichloroethylene results in increased phosphorylation of H2AX protein CTD PMID:29722447 H2ax Rat trichloroethene increases phosphorylation ISO H2ax (Mus musculus) 6480464 Trichloroethylene results in increased phosphorylation of H2AX protein CTD PMID:29722447 H2ax Rat trichostatin A affects expression ISO H2AX (Homo sapiens) 6480464 trichostatin A affects the expression of H2AX mRNA CTD PMID:28542535 H2ax Rat trichostatin A multiple interactions EXP 6480464 trichostatin A inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein] CTD PMID:25015661 H2ax Rat triciribine increases expression ISO H2AX (Homo sapiens) 6480464 triciribine results in increased expression of H2AX mRNA CTD PMID:29117515 H2ax Rat trimellitic anhydride increases expression ISO H2ax (Mus musculus) 6480464 trimellitic anhydride results in increased expression of H2AX mRNA CTD PMID:19042947 H2ax Rat triphenyl phosphate increases expression ISO H2AX (Homo sapiens) 6480464 triphenyl phosphate results in increased expression of H2AX protein CTD PMID:36372259 H2ax Rat triphenyl phosphate increases expression ISO H2ax (Mus musculus) 6480464 triphenyl phosphate results in increased expression of H2AX protein CTD PMID:37149271 H2ax Rat Triptolide increases expression ISO H2ax (Mus musculus) 6480464 triptolide results in increased expression of H2AX mRNA; triptolide results in increased expression of H2AX more ... CTD PMID:32835833|PMID:38960301 H2ax Rat Triptolide multiple interactions ISO H2ax (Mus musculus) 6480464 ferrostatin-1 inhibits the reaction [triptolide results in increased expression of H2AX protein]; GPX4 protein inhibits more ... CTD PMID:38960301 H2ax Rat Triptolide increases expression ISO H2AX (Homo sapiens) 6480464 triptolide results in increased expression of H2AX protein CTD PMID:36990132 H2ax Rat Triptolide increases phosphorylation ISO H2AX (Homo sapiens) 6480464 triptolide results in increased phosphorylation of H2AX protein CTD PMID:31218727 H2ax Rat tris(2-butoxyethyl) phosphate increases expression ISO H2AX (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate results in increased expression of H2AX protein CTD PMID:38823534 H2ax Rat tris(2-chloroethyl) phosphate increases phosphorylation EXP 6480464 tris(chloroethyl)phosphate results in increased phosphorylation of H2AX protein CTD PMID:38301995 H2ax Rat troglitazone decreases expression ISO H2AX (Homo sapiens) 6480464 Troglitazone results in decreased expression of H2AX mRNA CTD PMID:19140230 H2ax Rat trovafloxacin multiple interactions ISO H2AX (Homo sapiens) 6480464 [TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartic more ... CTD PMID:25748550 H2ax Rat trovafloxacin decreases expression ISO H2ax (Mus musculus) 6480464 trovafloxacin results in decreased expression of H2AX mRNA CTD PMID:35537566 H2ax Rat trovafloxacin increases phosphorylation ISO H2ax (Mus musculus) 6480464 trovafloxacin results in increased phosphorylation of H2AX protein CTD PMID:24817034 H2ax Rat trovafloxacin increases expression ISO H2AX (Homo sapiens) 6480464 trovafloxacin results in increased expression of H2AX protein modified form CTD PMID:25748550 H2ax Rat UDP multiple interactions ISO H2AX (Homo sapiens) 6480464 Uridine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat usnic acid increases expression ISO H2AX (Homo sapiens) 6480464 usnic acid results in increased expression of H2AX protein; usnic acid results in increased expression more ... CTD PMID:27369375|PMID:31715134 H2ax Rat usnic acid increases phosphorylation ISO H2AX (Homo sapiens) 6480464 usnic acid results in increased phosphorylation of H2AX protein CTD PMID:38724177 H2ax Rat usnic acid multiple interactions ISO H2AX (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [usnic acid results in increased expression of H2AX protein]; NFE2L2 protein more ... CTD PMID:27369375|PMID:31715134 H2ax Rat UTP multiple interactions ISO H2AX (Homo sapiens) 6480464 Uridine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization more ... CTD PMID:32941855 H2ax Rat valproic acid affects expression ISO H2AX (Homo sapiens) 6480464 Valproic Acid affects the expression of H2AX mRNA CTD PMID:25979313 H2ax Rat valproic acid decreases expression ISO H2ax (Mus musculus) 6480464 Valproic Acid results in decreased expression of H2AX mRNA; Valproic Acid results in decreased expression more ... CTD PMID:21427059|PMID:21708246 H2ax Rat valproic acid increases expression ISO H2ax (Mus musculus) 6480464 Valproic Acid results in increased expression of H2AX protein CTD PMID:21708246 H2ax Rat vancomycin decreases expression ISO H2ax (Mus musculus) 6480464 Vancomycin results in decreased expression of H2AX mRNA CTD PMID:18930951 H2ax Rat veliparib increases expression ISO H2AX (Homo sapiens) 6480464 [veliparib results in increased expression of PARP1 protein] which results in increased expression of H2AX more ... CTD PMID:17505006|PMID:21917757|PMID:27694308 H2ax Rat veliparib multiple interactions ISO H2AX (Homo sapiens) 6480464 [veliparib co-treated with Topotecan] results in increased expression of H2AX protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the more ... CTD PMID:21227924|PMID:21795476|PMID:27694308 H2ax Rat versicolorin A increases expression ISO H2AX (Homo sapiens) 6480464 versicolorin A results in increased expression of H2AX protein CTD PMID:32106047|PMID:33984424 H2ax Rat versicolorin A multiple interactions ISO H2AX (Homo sapiens) 6480464 [Aflatoxin B1 co-treated with versicolorin A] results in increased expression of H2AX protein; versicolorin A more ... CTD PMID:33984424 H2ax Rat vincristine multiple interactions ISO H2AX (Homo sapiens) 6480464 [CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX more ... CTD PMID:28669723 H2ax Rat vorinostat increases activity ISO H2AX (Homo sapiens) 6480464 Vorinostat results in increased activity of H2AX protein CTD PMID:20460513 H2ax Rat vorinostat increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Vorinostat results in increased phosphorylation of H2AX protein CTD PMID:20531243 H2ax Rat vorinostat increases expression ISO H2AX (Homo sapiens) 6480464 Vorinostat results in increased expression of H2AX protein; Vorinostat results in increased expression of H2AX more ... CTD PMID:20679231|PMID:22923501 H2ax Rat vorinostat multiple interactions ISO H2AX (Homo sapiens) 6480464 Resveratrol promotes the reaction [Vorinostat results in increased expression of H2AX protein] CTD PMID:22923501 H2ax Rat wogonin increases expression ISO H2AX (Homo sapiens) 6480464 wogonin results in increased expression of H2AX protein CTD PMID:32671444 H2ax Rat wogonin multiple interactions ISO H2AX (Homo sapiens) 6480464 wogonin inhibits the reaction [Benzo(a)pyrene results in increased expression of H2AX protein] CTD PMID:37515497 H2ax Rat wortmannin multiple interactions ISO H2AX (Homo sapiens) 6480464 Wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; Wortmannin inhibits the more ... CTD PMID:17991895|PMID:20878124|PMID:22409540|PMID:34784199 H2ax Rat Xanthatin increases expression ISO H2AX (Homo sapiens) 6480464 xanthatin results in increased expression of H2AX protein modified form CTD PMID:29074359 H2ax Rat yttrium chloride increases phosphorylation EXP 6480464 yttrium chloride results in increased phosphorylation of H2AX protein CTD PMID:35088107 H2ax Rat yttrium chloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein] CTD PMID:35088107 H2ax Rat zearalenone increases expression ISO H2ax (Mus musculus) 6480464 Zearalenone results in increased expression of H2AX protein modified form CTD PMID:28089945|PMID:28552778|PMID:35650142 H2ax Rat zearalenone decreases expression ISO H2ax (Mus musculus) 6480464 Zearalenone results in decreased expression of H2AX protein CTD PMID:35504548 H2ax Rat zebularine increases expression ISO H2AX (Homo sapiens) 6480464 pyrimidin-2-one beta-ribofuranoside results in increased expression of H2AX protein CTD PMID:17991895 H2ax Rat zidovudine increases phosphorylation ISO H2AX (Homo sapiens) 6480464 Zidovudine results in increased phosphorylation of H2AX protein CTD PMID:34510228 H2ax Rat zinc atom increases expression ISO H2AX (Homo sapiens) 6480464 Zinc deficiency results in increased expression of H2AX mRNA CTD PMID:18356318 H2ax Rat zinc atom multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in more ... CTD PMID:31542844 H2ax Rat zinc dichloride increases expression ISO H2AX (Homo sapiens) 6480464 zinc chloride results in increased expression of H2AX mRNA CTD PMID:18947441 H2ax Rat zinc oxide increases activity ISO H2ax (Mus musculus) 6480464 Zinc Oxide analog results in increased activity of H2AX protein CTD PMID:24614525 H2ax Rat zinc oxide multiple interactions ISO H2ax (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased activity of H2AX protein] CTD PMID:24614525 H2ax Rat zinc(0) increases expression ISO H2AX (Homo sapiens) 6480464 Zinc deficiency results in increased expression of H2AX mRNA CTD PMID:18356318 H2ax Rat zinc(0) multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in more ... CTD PMID:31542844 H2ax Rat zoledronic acid increases expression ISO H2AX (Homo sapiens) 6480464 Zoledronic Acid results in increased expression of H2AX mRNA CTD PMID:20977926