GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H2ax | increases expression | EXP | | 6480464 | CTD | tributyltin results in increased expression of H2AX protein modified form | PMID:26079211 | H2ax | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Phycocyanin inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form] | PMID:26079211 | H2ax | increases expression | ISO | H2AX (Homo sapiens) | 6480464 | CTD | tributyltin results in increased expression of H2AX protein modified form | PMID:31401084 | H2ax | increases phosphorylation | ISO | H2AX (Homo sapiens) | 6480464 | CTD | tributyltin results in increased phosphorylation of H2AX protein | PMID:36319700 | H2ax | increases phosphorylation | ISO | H2ax (Mus musculus) | 6480464 | CTD | tributyltin results in increased phosphorylation of H2AX protein | PMID:36319700 | H2ax | multiple interactions | ISO | H2AX (Homo sapiens) | 6480464 | CTD | 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [tributyltin results in increased phosphorylation of H2AX protein]; DFFB protein promotes the reaction [tributyltin results in increased expression of H2AX protein modified form] | PMID:31401084 PMID:36319700 | |
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