GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H2ax | decreases expression | EXP | | 6480464 | CTD | cobaltous chloride results in decreased expression of H2AX mRNA | PMID:24386269 | H2ax | decreases expression | ISO | H2AX (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in decreased expression of H2AX mRNA | PMID:19376846 | H2ax | increases phosphorylation | ISO | H2AX (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased phosphorylation of H2AX protein | PMID:22172632 | H2ax | multiple interactions | ISO | H2AX (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]]; cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein] | PMID:22172632 | | ||||||||||||||||||||||
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