GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H2ax | increases expression | ISO | H2AX (Homo sapiens) | 6480464 | CTD | aflatoxin G1 results in increased expression of H2AX protein modified form | PMID:23907605 | H2ax | increases phosphorylation | ISO | H2AX (Homo sapiens) | 6480464 | CTD | aflatoxin G1 results in increased phosphorylation of H2AX protein | PMID:36997055 | H2ax | multiple interactions | ISO | H2AX (Homo sapiens) | 6480464 | CTD | CYP2E1 promotes the reaction [aflatoxin G1 results in increased expression of H2AX protein]; Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein modified form]; Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein modified form]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]]; TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein] | PMID:23907605 PMID:36997055 | H2ax | multiple interactions | ISO | H2ax (Mus musculus) | 6480464 | CTD | aflatoxin G1 results in increased expression of and results in increased localization of H2AX protein; TNFRSF1B protein inhibits the reaction [aflatoxin G1 results in increased expression of H2AX protein] | PMID:36997055 | | ||||||||||||||||||||||
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