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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566119
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H2ax
Name: H2A.X variant histone
Acc ID: CHEBI:5141
Term: fomepizole
Definition: A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Chemical ID: MESH:C010238
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2axmultiple interactionsISOH2AX (Homo sapiens)6480464CTDFomepizole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]PMID:28300663
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