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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566119 Species: Rattus norvegicus RGD Object: Gene Symbol: H2afx Name: H2A histone family, member X

Acc ID: CHEBI:50225 Term: razoxane Definition: A N-alkylpiperazine that has formula C11H16N4O4. CasRN: 21416-87-5 Chemical ID: MESH:D011929

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Razoxane inhibits the reaction [Doxorubicin results in increased expression of H2AFX protein] Razoxane inhibits the reaction [Etoposide results in increased expression of H2AFX protein]	PMID:17875725