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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dipyridodiazepine
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Accession:CHEBI:63667 term browser browse the term
Definition:An organic heterotricyclic compound whose skeleton consists of a diazepine ring which is fused to two pyridine rings.
Synonyms:related_synonym: dipyridodiazepines


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nevirapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Nevirapine results in increased expression of ABCB1A mRNA CTD PMID:23947594 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression EXP Nevirapine metabolite results in decreased expression of ADAMTS9 mRNA; Nevirapine results in decreased expression of ADAMTS9 mRNA CTD PMID:23947594 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression EXP Nevirapine metabolite results in increased expression of ADGRF5 mRNA CTD PMID:23947594 NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
increases secretion		 ISO Nevirapine results in increased expression of ADIPOQ mRNA
Nevirapine results in increased secretion of ADIPOQ protein		 CTD PMID:21619898 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Nevirapine metabolite results in decreased expression of AIF1 mRNA CTD PMID:23947594 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Alb albumin affects binding ISO Nevirapine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Nevirapine results in increased expression of APOA1 protein CTD PMID:19667106 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Ar androgen receptor increases expression ISO Nevirapine results in increased expression of AR mRNA; Nevirapine results in increased expression of AR protein CTD PMID:19152342 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression EXP Nevirapine metabolite results in decreased expression of ARMCX2 mRNA; Nevirapine results in decreased expression of ARMCX2 mRNA CTD PMID:23947594 NCBI chr  X:97,980,662...97,985,523
Ensembl chr  X:97,980,660...97,985,552 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP Nevirapine metabolite results in increased expression of ARNT mRNA CTD PMID:23947594 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Nevirapine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Cd36 CD36 molecule increases expression EXP Nevirapine metabolite results in increased expression of CD36 mRNA CTD PMID:23947594 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Nevirapine results in increased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Nevirapine results in increased expression of CES2 mRNA CTD PMID:23947594 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO Nevirapine results in increased expression of CIITA CTD PMID:26626330 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Clec4a1 C-type lectin domain family 4, member A1 decreases expression EXP Nevirapine results in decreased expression of CLEC4A1 mRNA CTD PMID:23947594 NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008 		JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression EXP Nevirapine results in decreased expression of CLEC4A3 mRNA CTD PMID:23947594 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817 		JBrowse link
G Clec4m C-type lectin domain family 4 member M increases expression EXP Nevirapine metabolite results in increased expression of CD209B mRNA CTD PMID:23947594 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539 		JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression EXP Nevirapine results in decreased expression of COTL1 mRNA CTD PMID:23947594 NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689 		JBrowse link
G Cux2 cut-like homeobox 2 decreases expression EXP Nevirapine metabolite results in decreased expression of CUX2 mRNA CTD PMID:23947594 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP2B1 mRNA; Nevirapine results in increased expression of CYP2B1 mRNA CTD PMID:23947594 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects binding EXP Nevirapine binds to CYP2C11 protein CTD PMID:22793666 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects binding ISO Nevirapine binds to CYP3A4 protein CTD PMID:22793666 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects binding
increases expression		 EXP Nevirapine binds to CYP3A23-3A1 protein
Nevirapine results in increased expression of CYP3A23-3A1 mRNA		 CTD PMID:22793666 PMID:23947594 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP Nevirapine results in increased expression of CYP3A9 mRNA CTD PMID:23947594 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP4B1 mRNA CTD PMID:23947594 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Dapk1 death associated protein kinase 1 increases expression EXP Nevirapine metabolite results in increased expression of DAPK1 mRNA CTD PMID:23947594 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP Nevirapine metabolite results in decreased expression of DBP mRNA CTD PMID:23947594 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP Nevirapine results in decreased expression of DDHD1 mRNA CTD PMID:23947594 NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression EXP Nevirapine results in increased expression of DIP2A mRNA CTD PMID:23947594 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Nevirapine metabolite results in increased expression of DNAJB5 mRNA CTD PMID:23947594 NCBI chr 5:57,176,840...57,186,067
Ensembl chr 5:57,176,845...57,185,490 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Nevirapine results in increased expression of EDEM1 mRNA CTD PMID:23947594 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Egf epidermal growth factor decreases expression ISO Nevirapine results in decreased expression of EGF mRNA CTD PMID:19152342 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression EXP Nevirapine results in decreased expression of EPB41L3 mRNA CTD PMID:23947594 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Ereg epiregulin increases expression ISO Nevirapine results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of ESM1 mRNA; Nevirapine results in increased expression of ESM1 mRNA CTD PMID:23947594 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression EXP Nevirapine results in increased expression of FAM107A mRNA CTD PMID:23947594 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396 		JBrowse link
G Fibin fin bud initiation factor homolog increases expression EXP Nevirapine results in increased expression of FIBIN mRNA CTD PMID:23947594 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Nevirapine metabolite results in increased expression of FKBP5 mRNA; Nevirapine results in increased expression of FKBP5 mRNA CTD PMID:23947594 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of FMO1 mRNA CTD PMID:23947594 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Nevirapine results in increased expression of GADD45B mRNA CTD PMID:23947594 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Nevirapine metabolite results in decreased expression of GLUL mRNA CTD PMID:23947594 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases glutathionylation ISO GSTA1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases glutathionylation ISO GSTM1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases glutathionylation ISO GSTP1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gzma granzyme A decreases expression EXP Nevirapine metabolite results in decreased expression of GZMA mRNA CTD PMID:23947594 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G Gzmf granzyme F decreases expression EXP Nevirapine metabolite results in decreased expression of GZMF mRNA CTD PMID:23947594 NCBI chr15:30,005,361...30,018,649
Ensembl chr15:30,007,267...30,018,649 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HAO2 mRNA; Nevirapine results in decreased expression of HAO2 mRNA CTD PMID:23947594 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hdc histidine decarboxylase decreases expression EXP Nevirapine metabolite results in decreased expression of HDC mRNA CTD PMID:23947594 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hgf hepatocyte growth factor decreases secretion ISO Nevirapine results in decreased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Nevirapine metabolite results in increased expression of HMGCS2 mRNA; Nevirapine results in increased expression of HMGCS2 mRNA CTD PMID:23947594 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression EXP Nevirapine metabolite results in increased expression of HPGD mRNA CTD PMID:23947594 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HSD17B2 mRNA CTD PMID:23947594 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Ifng interferon gamma increases expression ISO
EXP		 Nevirapine results in increased expression of IFNG protein CTD PMID:23947594 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igh-6 immunoglobulin heavy chain 6 increases expression EXP Nevirapine results in increased expression of IGH-6 mRNA CTD PMID:23947594
G Il1b interleukin 1 beta increases expression ISO Nevirapine results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 increases expression EXP Nevirapine metabolite results in increased expression of IL22RA2 mRNA CTD PMID:23947594 NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844 		JBrowse link
G Il24 interleukin 24 increases expression ISO Nevirapine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 decreases secretion ISO Nevirapine results in decreased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Nevirapine metabolite results in decreased expression of INHBE mRNA CTD PMID:23947594 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Nevirapine results in increased expression of INMT mRNA CTD PMID:23947594 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Nevirapine results in increased expression of INSIG2 mRNA CTD PMID:23947594 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Irgm immunity-related GTPase M decreases expression EXP Nevirapine results in decreased expression of IRGM mRNA CTD PMID:23947594 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP Nevirapine results in increased expression of ITPR1 mRNA CTD PMID:23947594 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Klf15 KLF transcription factor 15 increases expression EXP Nevirapine metabolite results in increased expression of KLF15 mRNA CTD PMID:23947594 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression ISO Nevirapine results in increased expression of KLK3 mRNA; Nevirapine results in increased expression of KLK3 protein CTD PMID:19152342 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Krt18 keratin 18 increases expression ISO Nevirapine results in increased expression of KRT18 protein CTD PMID:19152342 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt23 keratin 23 increases expression EXP Nevirapine metabolite results in increased expression of KRT23 mRNA CTD PMID:23947594 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Nevirapine results in increased expression of LCAT protein CTD PMID:19667106 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Ldaf1 lipid droplet assembly factor 1 decreases expression EXP Nevirapine results in decreased expression of LDAF1 mRNA CTD PMID:23947594 NCBI chr 1:174,484,438...174,503,037
Ensembl chr 1:174,484,447...174,503,036 		JBrowse link
G Lep leptin increases expression ISO Nevirapine results in increased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lifr LIF receptor subunit alpha increases expression EXP Nevirapine metabolite results in increased expression of LIFR mRNA CTD PMID:23947594 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Lipg lipase G, endothelial type decreases expression EXP Nevirapine metabolite results in decreased expression of LIPG mRNA; Nevirapine results in decreased expression of LIPG mRNA CTD PMID:23947594 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lpin1 lipin 1 increases expression EXP Nevirapine metabolite results in increased expression of LPIN1 mRNA CTD PMID:23947594 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lpl lipoprotein lipase increases expression ISO Nevirapine results in increased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression EXP Nevirapine metabolite results in increased expression of LRG1 mRNA CTD PMID:23947594 NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813 		JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression EXP Nevirapine results in decreased expression of LY86 mRNA CTD PMID:23947594 NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260 		JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP Nevirapine results in increased expression of MEOX2 mRNA CTD PMID:23947594 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Nevirapine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mgp matrix Gla protein increases expression EXP Nevirapine results in increased expression of MGP mRNA CTD PMID:23947594 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression EXP Nevirapine metabolite results in increased expression of MRC1 mRNA CTD PMID:23947594 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Ms4a7 membrane spanning 4-domains A7 decreases expression EXP Nevirapine results in decreased expression of MS4A7 mRNA CTD PMID:23947594 NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Nevirapine metabolite results in increased expression of NAMPT mRNA CTD PMID:23947594 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP Nevirapine results in increased expression of NDUFAF4 mRNA CTD PMID:23947594 NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 increases expression ISO Nevirapine results in increased expression of NLRC5 CTD PMID:26626330 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP Nevirapine metabolite results in decreased expression of NPAS2 mRNA; Nevirapine results in decreased expression of NPAS2 mRNA CTD PMID:23947594 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320 		JBrowse link
G Nptx2 neuronal pentraxin 2 increases expression EXP Nevirapine results in increased expression of NPTX2 mRNA CTD PMID:23947594 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP Nevirapine metabolite results in decreased expression of NR1D1 mRNA CTD PMID:23947594 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Nevirapine metabolite results in decreased expression of NREP mRNA; Nevirapine results in decreased expression of NREP mRNA CTD PMID:23947594 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression EXP Nevirapine results in decreased expression of P2RX7 mRNA CTD PMID:23947594 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 decreases expression EXP Nevirapine results in decreased expression of PCP4L1 mRNA CTD PMID:23947594 NCBI chr13:83,588,992...83,612,631
Ensembl chr13:83,588,992...83,609,966 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Nevirapine metabolite results in increased expression of PDK4 mRNA CTD PMID:23947594 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Nevirapine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression EXP Nevirapine results in increased expression of PIK3IP1 mRNA CTD PMID:23947594 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pir pirin increases expression EXP Nevirapine metabolite results in increased expression of PIR mRNA CTD PMID:23947594 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Pira2 paired-Ig-like receptor A2 decreases expression EXP Nevirapine results in decreased expression of PIRA2 mRNA CTD PMID:23947594 NCBI chr 1:65,352,125...65,422,842
Ensembl chr 1:65,415,946...65,422,853 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Nevirapine metabolite results in increased expression of PNPLA2 mRNA CTD PMID:23947594 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Nevirapine metabolite results in increased expression of POR mRNA; Nevirapine results in increased expression of POR mRNA CTD PMID:23947594 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Nevirapine results in increased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP Nevirapine metabolite results in decreased expression of PPP2R2B mRNA; Nevirapine results in decreased expression of PPP2R2B mRNA CTD PMID:23947594 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Prf1 perforin 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PRF1 mRNA CTD PMID:23947594 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PYCR1 mRNA CTD PMID:23947594 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP Nevirapine results in increased expression of RBM3 mRNA CTD PMID:23947594 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Retreg1 reticulophagy regulator 1 increases expression EXP Nevirapine metabolite results in increased expression of RETREG1 mRNA; Nevirapine results in increased expression of RETREG1 mRNA CTD PMID:23947594 NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
G Rhbdd2 rhomboid domain containing 2 increases expression EXP Nevirapine results in increased expression of RHBDD2 mRNA CTD PMID:23947594 NCBI chr12:21,043,605...21,054,305
Ensembl chr12:21,043,608...21,054,289 		JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression EXP Nevirapine metabolite results in decreased expression of RPRM mRNA CTD PMID:23947594 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998 		JBrowse link
G S100a7a S100 calcium binding protein A7A increases expression EXP Nevirapine metabolite results in increased expression of S100A7A mRNA CTD PMID:23947594 NCBI chr 2:176,151,405...176,155,846
Ensembl chr 2:176,151,288...176,156,441 		JBrowse link
G Scp2 sterol carrier protein 2 increases expression ISO Nevirapine results in increased expression of SCP2 CTD PMID:26626330 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Slamf9 SLAM family member 9 decreases expression EXP Nevirapine results in decreased expression of SLAMF9 mRNA CTD PMID:23947594 NCBI chr13:84,941,896...84,944,749
Ensembl chr13:84,941,982...84,944,748 		JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Nevirapine metabolite results in decreased expression of SLC34A2 mRNA CTD PMID:23947594 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Nevirapine results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
decreases expression		 ISO
EXP		 Nevirapine results in increased expression of SREBF1 mRNA
Nevirapine metabolite results in decreased expression of SREBF1 mRNA		 CTD PMID:21619898 PMID:23947594 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases activity EXP Nevirapine metabolite results in increased activity of SULT1A1 protein; Nevirapine results in increased activity of SULT1A1 protein CTD PMID:27417440 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tg thyroglobulin increases expression ISO Nevirapine results in increased expression of TG mRNA; Nevirapine results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tmem64 transmembrane protein 64 increases expression EXP Nevirapine metabolite results in increased expression of TMEM64 mRNA; Nevirapine results in increased expression of TMEM64 mRNA CTD PMID:23947594 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Nevirapine results in increased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tox3 TOX high mobility group box family member 3 increases expression EXP Nevirapine results in increased expression of TOX3 mRNA CTD PMID:23947594 NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148 		JBrowse link
G Tpo thyroid peroxidase increases expression ISO Nevirapine results in increased expression of TPO mRNA; Nevirapine results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Trim24 tripartite motif-containing 24 decreases expression EXP Nevirapine results in decreased expression of TRIM24 mRNA CTD PMID:23947594 NCBI chr 4:66,567,342...66,692,029
Ensembl chr 4:66,566,686...66,717,241 		JBrowse link
G Trim63 tripartite motif containing 63 increases expression EXP Nevirapine metabolite results in increased expression of TRIM63 mRNA CTD PMID:23947594 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Nevirapine results in increased expression of TSC22D3 mRNA CTD PMID:23947594 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein; Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Nevirapine results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP Nevirapine results in increased expression of TSKU mRNA CTD PMID:23947594 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588 		JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO Nevirapine results in increased expression of UCP1 CTD PMID:16038477 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Nevirapine metabolite results in increased expression of UCP3 mRNA CTD PMID:23947594 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of VCAM1 mRNA CTD PMID:23947594 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nevirapine results in decreased expression of VEGFA mRNA CTD PMID:19152342 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Nevirapine metabolite results in decreased expression of VSNL1 mRNA; Nevirapine results in decreased expression of VSNL1 mRNA CTD PMID:23947594 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 increases expression EXP Nevirapine results in increased expression of ZAP70 mRNA CTD PMID:23947594 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      atom 19839
        nonmetal atom 19777
          nitrogen atom 18962
            nitrogen molecular entity 18962
              organonitrogen compound 18812
                organonitrogen heterocyclic compound 18154
                  dipyridodiazepine 134
                    12-hydroxynevirapine 0
                    nevirapine + 134
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteropolycyclic compound 18301
                                    organic heterotricyclic compound 15642
                                      dipyridodiazepine 134
                                        12-hydroxynevirapine 0
                                        nevirapine + 134
paths to the root