Adgrf5 (adhesion G protein-coupled receptor F5) - Rat Genome Database

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Gene: Adgrf5 (adhesion G protein-coupled receptor F5) Rattus norvegicus
Analyze
Symbol: Adgrf5
Name: adhesion G protein-coupled receptor F5
RGD ID: 621679
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; energy reserve metabolic process; and fat cell differentiation. Predicted to act upstream of or within several processes, including glomerular filtration; negative regulation of macrophage activation; and pharyngeal arch artery morphogenesis. Predicted to be located in apical part of cell and cell surface. Predicted to be active in cytoplasmic vesicle. Orthologous to human ADGRF5 (adhesion G protein-coupled receptor F5); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: G protein-coupled hepta-helical receptor Ig-Hepta; G protein-coupled receptor 116; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116; Gpr116; Gprhep; Ig-Hepta; probable G-protein coupled receptor 116
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8925,014,861 - 25,128,045 (-)NCBIGRCr8
mRatBN7.2917,517,596 - 17,624,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,520,009 - 17,623,968 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx926,112,113 - 26,215,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,186,682 - 31,289,610 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,475,906 - 29,578,852 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0920,091,121 - 20,195,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,091,099 - 20,195,566 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,967,333 - 19,071,668 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,217,956 - 13,323,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,215,277 - 13,320,737 (-)NCBI
Celera915,237,160 - 15,339,123 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fipronil  (EXP)
gentamycin  (EXP)
isoprenaline  (ISO)
levonorgestrel  (ISO)
methamphetamine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-Nitrosopyrrolidine  (ISO)
nevirapine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
rotenone  (EXP)
testosterone undecanoate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
triadimefon  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
apical part of cell  (IEA,ISO)
cell surface  (IEA,ISO)
cytoplasmic vesicle  (IBA,IEA,ISO)
plasma membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Ig-hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs. Abe J, etal., J Biol Chem 1999 Jul 9;274(28):19957-64.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11973329   PMID:22971422   PMID:23590306   PMID:23684610   PMID:25778400   PMID:28806758  


Genomics

Comparative Map Data
Adgrf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8925,014,861 - 25,128,045 (-)NCBIGRCr8
mRatBN7.2917,517,596 - 17,624,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,520,009 - 17,623,968 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx926,112,113 - 26,215,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,186,682 - 31,289,610 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,475,906 - 29,578,852 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0920,091,121 - 20,195,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,091,099 - 20,195,566 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,967,333 - 19,071,668 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,217,956 - 13,323,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,215,277 - 13,320,737 (-)NCBI
Celera915,237,160 - 15,339,123 (-)NCBICelera
Cytogenetic Map9q13NCBI
ADGRF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,852,522 - 46,954,939 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,852,522 - 46,954,943 (-)EnsemblGRCh38hg38GRCh38
GRCh37646,820,259 - 46,922,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,928,201 - 47,030,634 (-)NCBINCBI36Build 36hg18NCBI36
Build 34646,928,297 - 46,990,825NCBI
Celera648,372,598 - 48,475,024 (-)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef646,543,478 - 46,645,785 (-)NCBIHuRef
CHM1_1646,823,487 - 46,925,912 (-)NCBICHM1_1
T2T-CHM13v2.0646,689,996 - 46,792,404 (-)NCBIT2T-CHM13v2.0
Adgrf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,671,225 - 43,770,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,671,342 - 43,770,448 (+)EnsemblGRCm39 Ensembl
GRCm381743,360,329 - 43,459,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,360,451 - 43,459,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv371743,526,415 - 43,596,506 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361742,825,075 - 42,924,198 (+)NCBIMGSCv36mm8
Celera1746,814,258 - 46,884,453 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.73NCBI
Adgrf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,639,891 - 11,688,257 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,639,555 - 11,710,362 (-)NCBIChiLan1.0ChiLan1.0
ADGRF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,350,720 - 61,452,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,216,959 - 57,319,166 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0646,438,128 - 46,540,325 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,703,158 - 47,805,347 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,700,570 - 47,772,510 (-)Ensemblpanpan1.1panPan2
ADGRF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11215,013,567 - 15,115,889 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1215,006,949 - 15,086,116 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1215,045,001 - 15,147,394 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01215,510,094 - 15,612,365 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1215,512,606 - 15,612,218 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11215,024,852 - 15,127,029 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01215,117,916 - 15,219,946 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,263,867 - 15,336,692 (-)NCBIUU_Cfam_GSD_1.0
Adgrf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,457,310 - 50,546,121 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647613,414,058 - 13,504,509 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647613,414,087 - 13,503,926 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,640,257 - 41,769,232 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1741,640,256 - 41,769,422 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,301,437 - 48,429,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,323,613 - 25,427,370 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,356,427 - 25,430,061 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,866,043 - 46,976,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,778,170 - 13,843,723 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475413,778,573 - 13,843,931 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adgrf5
843 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:50
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000015223
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat

Markers in Region
D9Got26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,584,551 - 17,584,707 (+)MAPPERmRatBN7.2
Rnor_6.0920,156,566 - 20,156,721NCBIRnor6.0
Rnor_5.0919,032,778 - 19,032,933UniSTSRnor5.0
RGSC_v3.4913,283,515 - 13,283,671RGDRGSC3.4
RGSC_v3.4913,283,516 - 13,283,671UniSTSRGSC3.4
RGSC_v3.1913,280,838 - 13,280,993RGD
Celera915,300,501 - 15,300,656UniSTS
RH 3.4 Map9125.9UniSTS
RH 3.4 Map9125.9RGD
RH 2.0 Map90.0RGD
Cytogenetic Map9q12UniSTS
D9Got23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,565,176 - 17,565,422 (+)MAPPERmRatBN7.2
Rnor_6.0920,138,702 - 20,138,947NCBIRnor6.0
Rnor_5.0919,014,914 - 19,015,159UniSTSRnor5.0
RGSC_v3.4913,262,121 - 13,262,367RGDRGSC3.4
RGSC_v3.4913,262,122 - 13,262,367UniSTSRGSC3.4
RGSC_v3.1913,259,444 - 13,259,689RGD
Celera915,281,341 - 15,281,588UniSTS
RH 3.4 Map9105.3UniSTS
RH 3.4 Map9105.3RGD
RH 2.0 Map999.8RGD
Cytogenetic Map9q12UniSTS
D9Wox36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2917,521,251 - 17,521,491 (+)MAPPERmRatBN7.2
Rnor_6.0920,094,776 - 20,095,015NCBIRnor6.0
Rnor_5.0918,970,988 - 18,971,227UniSTSRnor5.0
RGSC_v3.4913,218,196 - 13,218,435UniSTSRGSC3.4
Celera915,237,400 - 15,237,639UniSTS
Cytogenetic Map9q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 35 25 14 14 14 8 10 35 35 27 11 8
Low 3 8 32 27 5 27 1 39 14
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_139110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB019120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC119458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000015223   ⟹   ENSRNOP00000015223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,521,012 - 17,623,968 (-)Ensembl
Rnor_6.0 Ensembl920,094,536 - 20,195,566 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082904   ⟹   ENSRNOP00000071238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,521,012 - 17,623,968 (-)Ensembl
Rnor_6.0 Ensembl920,091,099 - 20,154,077 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118179   ⟹   ENSRNOP00000096657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,520,009 - 17,623,968 (-)Ensembl
RefSeq Acc Id: NM_139110   ⟹   NP_620810
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,018,277 - 25,121,237 (-)NCBI
mRatBN7.2917,521,012 - 17,623,968 (-)NCBI
Rnor_6.0920,094,536 - 20,195,566 (-)NCBI
Rnor_5.0918,967,333 - 19,071,668 (-)NCBI
RGSC_v3.4913,217,956 - 13,323,415 (-)RGD
Celera915,237,160 - 15,339,123 (-)RGD
Sequence:
RefSeq Acc Id: XM_008766832   ⟹   XP_008765054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,093,161 (-)NCBI
mRatBN7.2917,517,596 - 17,595,904 (-)NCBI
Rnor_6.0920,091,121 - 20,168,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766833   ⟹   XP_008765055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,121,369 (-)NCBI
mRatBN7.2917,517,596 - 17,624,107 (-)NCBI
Rnor_6.0920,091,121 - 20,195,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766834   ⟹   XP_008765056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,018,973 - 25,079,333 (-)NCBI
mRatBN7.2917,521,671 - 17,582,066 (-)NCBI
Rnor_6.0920,095,245 - 20,168,006 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083012   ⟹   XP_038938940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,079,333 (-)NCBI
mRatBN7.2917,517,596 - 17,582,066 (-)NCBI
RefSeq Acc Id: XM_039083013   ⟹   XP_038938941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,079,333 (-)NCBI
mRatBN7.2917,517,596 - 17,582,066 (-)NCBI
RefSeq Acc Id: XM_039083014   ⟹   XP_038938942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,093,161 (-)NCBI
mRatBN7.2917,517,596 - 17,592,525 (-)NCBI
RefSeq Acc Id: XM_063266630   ⟹   XP_063122700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,018,973 - 25,079,333 (-)NCBI
RefSeq Acc Id: XM_063266631   ⟹   XP_063122701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,128,045 (-)NCBI
RefSeq Acc Id: XM_063266632   ⟹   XP_063122702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8925,014,861 - 25,128,045 (-)NCBI
RefSeq Acc Id: NP_620810   ⟸   NM_139110
- Peptide Label: precursor
- UniProtKB: Q9WVT0 (UniProtKB/Swiss-Prot),   A6JJ39 (UniProtKB/TrEMBL),   A0A8I6AR34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765055   ⟸   XM_008766833
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AR34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765054   ⟸   XM_008766832
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AR34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765056   ⟸   XM_008766834
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AR34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071238   ⟸   ENSRNOT00000082904
RefSeq Acc Id: ENSRNOP00000015223   ⟸   ENSRNOT00000015223
RefSeq Acc Id: XP_038938942   ⟸   XM_039083014
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AR34 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938940   ⟸   XM_039083012
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZZ0 (UniProtKB/TrEMBL),   A0A8I6AR34 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938941   ⟸   XM_039083013
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AR34 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096657   ⟸   ENSRNOT00000118179
RefSeq Acc Id: XP_063122702   ⟸   XM_063266632
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063122701   ⟸   XM_063266631
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063122700   ⟸   XM_063266630
- Peptide Label: isoform X3
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WVT0-F1-model_v2 AlphaFold Q9WVT0 1-1349 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696558
Promoter ID:EPDNEW_R7082
Type:multiple initiation site
Name:Adgrf5_1
Description:adhesion G protein-coupled receptor F5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,195,601 - 20,195,661EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621679 AgrOrtholog
BioCyc Gene G2FUF-28104 BioCyc
Ensembl Genes ENSRNOG00000011154 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055020095 UniProtKB/Swiss-Prot
  ENSRNOG00060021816 UniProtKB/Swiss-Prot
  ENSRNOG00065023255 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015223 ENTREZGENE
  ENSRNOT00000015223.3 UniProtKB/Swiss-Prot
  ENSRNOT00000082904 ENTREZGENE
  ENSRNOT00000082904.2 UniProtKB/TrEMBL
  ENSRNOT00000118179.1 UniProtKB/TrEMBL
  ENSRNOT00055034326 UniProtKB/Swiss-Prot
  ENSRNOT00060037919 UniProtKB/Swiss-Prot
  ENSRNOT00065039830 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.220.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.960 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GAIN_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_Ig-hepta-like_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:245977 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 245977 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR F5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45813 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adgrf5 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGHEPTARCPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011154 RatGTEx
  ENSRNOG00055020095 RatGTEx
  ENSRNOG00060021816 RatGTEx
  ENSRNOG00065023255 RatGTEx
SMART GPS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82671 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZZ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR34 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ39 ENTREZGENE, UniProtKB/TrEMBL
  AGRF5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-16 Adgrf5  adhesion G protein-coupled receptor F5  Gpr116  G protein-coupled receptor 116  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gpr116  G protein-coupled receptor 116  Gprhep  G protein-coupled hepta-helical receptor Ig-Hepta  Symbol and Name updated 1299863 APPROVED
2004-02-11 Gprhep    Ig-Hepta  G protein-coupled hepta-helical receptor Ig-Hepta  Symbol updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Ig-Hepta  G protein-coupled hepta-helical receptor Ig-Hepta      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a long extracellular domain comprising Ig-like repeats 625424
gene_expression expressed predominantly in the lung 625424