Gene: Zap70 (zeta-chain (TCR) associated protein kinase 70)  Rattus norvegicus

Symbol: Zap70
Name: zeta-chain (TCR) associated protein kinase 70
Description: ENCODES a protein that exhibits ATP binding (ortholog); phosphotyrosine binding (ortholog); protein kinase activity (ortholog); INVOLVED IN beta selection (ortholog); immune response (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; primary immunodeficiency disease pathway; T cell receptor signaling pathway; ASSOCIATED WITH Immunologic Deficiency Syndromes (ortholog); Severe Combined Immunodeficiency (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); immunological synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC108902; Srk; syk-related protein tyrosine kinase; tyrosine-protein kinase ZAP-70; Zap70_mapped; zap70_mapped; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70 (mapped); zeta-chain (tcr) associated protein kinase 70 (mapped); zeta-chain (TCR) associated protein kinase 70kDa
Orthologs: Homo sapiens : ZAP70 (zeta-chain (TCR) associated protein kinase 70kDa)  HGNC
Mus musculus : Zap70 (zeta-chain (TCR) associated protein kinase)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map9q21 NCBI
RGSC Genome Assembly v5.0942,980,050 - 43,002,015+NCBI
RGSC Genome Assembly v3.4935,693,089 - 35,715,071+NCBI
Rat Celera Assembly936,755,106 - 36,777,088+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Zap70
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3983
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE