| 1307580 | Fbxo4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; FOUND IN cytoplasm (ortholog); SCF ubiquitin ligase complex (ortholog); ubiquitin ligase complex (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 2 | 54902394 | 54915388 | Rat | 122 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316856 | FBXO4 | F-box protein 4 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependen t ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] | 5 | 41925281 | 42040404 | Human | 119 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316857 | Fbxo4 | F-box protein 4 | Enables ubiquitin protein ligase activity and ubiquitin-like ligase-substrate adaptor activity. Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; protein destabilization; and regulation of macromolecule metabolic process. Part of SCF ubiquitin liga se complex. Is expressed in several structures, including craniocervical region bone; esophagus; lung; pituitary gland; and sensory organ. Orthologous to human FBXO4 (F-box protein 4). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 3993046 | 4009055 | Mouse | 137 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9007818 | Fbxo4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (ortholog); SCF ubiquitin ligase complex (ortholog); ubiquitin ligase complex (ortholog) | NW_004955426 | 26046742 | 26066747 | Chinchilla | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11958890 | FBXO4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred) | 5 | 68336673 | 68474481 | Bonobo | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12327420 | FBXO4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred) | 4 | 67620947 | 67664862 | Dog | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12447566 | Fbxo4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred) | NW_004936518 | 855304 | 873927 | Squirrel | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13952578 | FBXO4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18483154 | FBXO4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred) | | | | Green Monkey | 48 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907146 | Fbxo4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); ubiquitin ligase complex (inferred) | | | | Naked Mole-Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867307 | FBXO4 | F-box protein 4 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155237945 | fbxo4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626014237 | Fbxo4 | F-box protein 4 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular homeostasis (ortholog); cellular response to ionizing radiation (ortholog); cellular senescenc e (ortholog); FOUND IN cytoplasm (ortholog); SCF ubiquitin ligase complex (ortholog); ubiquitin ligase complex (ortholog) | | | | Black Rat | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233165 | fbxo4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1309781 | Fbxo40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH alpha-Zearalanol; b isphenol A; cyclophosphamide | 11 | 77299826 | 77318086 | Rat | 32 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320304 | FBXO40 | F-box protein 40 | Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] | 3 | 121593379 | 121630295 | Human | 35 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1320305 | Fbxo40 | F-box protein 40 | Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Involved in muscle cell differentiation. Located in cytoplasm. Orthologous to human FBXO40 (F-box protein 40). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 36783823 | 36811321 | Mouse | 33 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8779832 | Fbxo40 | F-box protein 40 | INVOLVED IN muscle cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog) | NW_004955427 | 20979180 | 20996654 | Chinchilla | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11835159 | FBXO40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | 3 | 118695215 | 118730183 | Bonobo | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12243215 | FBXO40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | 33 | 24841998 | 24899973 | Dog | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12570642 | Fbxo40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | NW_004936536 | 8045171 | 8064492 | Squirrel | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13974511 | FBXO40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | | | | Pig | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18635246 | FBXO40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | | | | Green Monkey | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918516 | Fbxo40 | F-box protein 40 | ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (inferred) | | | | Naked Mole-Rat | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083373 | fbxo40 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625870158 | Fbxo40 | F-box protein 40 | INVOLVED IN muscle cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN cytoplasm (ortholog) | | | | Black Rat | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1351223 | FBXO41 | F-box protein 41 | This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box prote ins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014] | 2 | 73254690 | 73284478 | Human | 60 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1557931 | Fbxo41 | F-box protein 41 | Acts upstream of or within chemical synaptic transmission; gene expression; and nervous system development. Predicted to be located in synapse. Is expressed in several structures, including forelimb bud; male reproductive gland or organ; nervous system; notochord; and sensory organ. Orthologous to h uman FBXO41 (F-box protein 41). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 85446556 | 85479976 | Mouse | 85 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1566130 | Fbxo41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog); FOUND IN synapse (inferred); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; gentamycin | 4 | 119565012 | 119597042 | Rat | 59 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8943358 | Fbxo41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | NW_004955424 | 12339588 | 12378116 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11911355 | FBXO41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | 2A | 73307478 | 73337242 | Bonobo | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12217340 | FBXO41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | 17 | 49585511 | 49613406 | Dog | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12573074 | Fbxo41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | NW_004936491 | 17035988 | 17048165 | Squirrel | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14251967 | FBXO41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18769846 | FBXO41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | | | | Green Monkey | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901084 | Fbxo41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | | | | Naked Mole-Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235779 | fbxo41 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626164911 | Fbxo41 | F-box protein 41 | INVOLVED IN chemical synaptic transmission (ortholog); dentate gyrus development (ortholog); gene expression (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1304787 | Fbxo42 | F-box protein 42 | INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 5 | 158734165 | 158792560 | Rat | 65 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312431 | FBXO42 | F-box protein 42 | Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box pr oteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010] | 1 | 16246840 | 16352480 | Human | 69 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1550029 | Fbxo42 | F-box protein 42 | Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in brain; glossopharyngeal ganglion; spinal cord; trigeminal ganglion; and vestibulo-cochlear ganglion. Orthologous to human FBXO4 span>2 (F-box protein 42). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 140875216 | 140931373 | Mouse | 79 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8977355 | Fbxo42 | F-box protein 42 | | NW_004955527 | 1967232 | 2049524 | Chinchilla | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11669530 | FBXO42 | F-box protein 42 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | 1 | 15383505 | 15489800 | Bonobo | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12358553 | FBXO42 | F-box protein 42 | | 2 | 81358204 | 81460603 | Dog | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12528955 | Fbxo42 | F-box protein 42 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | NW_004936474 | 3738332 | 3818796 | Squirrel | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14252504 | FBXO42 | F-box protein 42 | | | | | Pig | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18679569 | FBXO42 | F-box protein 42 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | | | | Green Monkey | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913409 | Fbxo42 | F-box protein 42 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | | | | Naked Mole-Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155258671 | fbxo42 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626128937 | Fbxo42 | F-box protein 42 | | | | | Black Rat | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1310225 | Fbxo43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus; negative regulation of cell cycle process (ortholog); negative regulation of meiotic nuclear division (ortholog); ASSOCIATED WITH Oocyte/Zygote/Em bryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; gentamycin | 7 | 69218298 | 69231873 | Rat | 68 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321003 | FBXO43 | F-box protein 43 | Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] | 8 | 100133351 | 100150569 | Human | 87 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1553428 | Fbxo43 | F-box protein 43 | Predicted to enable zinc ion binding activity. Acts upstream of or within negative regulation of meiotic nuclear division and negative regulation of protein catabolic process. Located in female germ cell nucleus. Is expressed in early conceptus and gonad. Human ortholog(s) of this gene implicated in spermatogenic failure 64. Orthologous to human FBXO43 (F-box protein 43). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 36150206 | 36170086 | Mouse | 80 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9057106 | Fbxo43 | F-box protein 43 | INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of cell cycle process (ortholog); negative regulation of meiotic nuclear division (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (ortholog) | NW_004955417 | 15394481 | 15406751 | Chinchilla | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11911303 | FBXO43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of protein catabolic process (ortholog); ASSOCIATED WIT H Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (inferred) | 8 | 96774246 | 96786933 | Bonobo | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12402396 | FBXO43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of protein catabolic process (ortholog); ASSOCIATED WIT H Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (ortholog) | 13 | 2037270 | 2057465 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12571096 | Fbxo43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of protein catabolic process (ortholog); ASSOCIATED WIT H Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (inferred) | NW_004936470 | 43091516 | 43100973 | Squirrel | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14122129 | FBXO43 | F-box protein 43 | ENCODES a protein that exhibits G-protein alpha-subunit binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of protein catabolic process (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18570886 | FBXO43 | F-box protein 43 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of meiotic nuclear division (ortholog); negative regulation of protein catabolic process (ortholog); ASSOCIATED WIT H Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245868 | fbxo43 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626064431 | Fbxo43 | F-box protein 43 | INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); negative regulation of cell cycle process (ortholog); negative regulation of meiotic nuclear division (ortholog); ASSOCIATED WITH Oocyte/Zygote/Embryo Maturation Arrest 12 (ortholog); spermatogenic failure 64 (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1558178 | Fbxo44 | F-box protein 44 | Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and glycoprotein catabolic process. Predicted to act upstream of or within proteasomal protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in brain; gut; and male reproductive gland or organ. Orthologous to human FBXO44 (F-box protein 44). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 148237256 | 148244663 | Mouse | 68 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562463 | Fbxo44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neo plasms (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 5 | 163866517 | 163875928 | Rat | 67 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606989 | FBXO44 | F-box protein 44 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependen t ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015] | 1 | 11654407 | 11663327 | Human | 68 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8993649 | Fbxo44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neo plasms (ortholog); FOUND IN nucleus (ortholog); SCF ubiquitin ligase complex (ortholog) | NW_004955486 | 2204470 | 2210604 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12243206 | FBXO44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN proteasomal protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); SCF ubiq uitin ligase complex (inferred) | 2 | 84557468 | 84562578 | Dog | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12631773 | Fbxo44 | F-box protein 44 | ENCODES a protein that exhibits carbohydrate binding (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN proteasomal protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Ne oplasms (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); SCF ubiquitin ligase complex (inferred) | NW_004936474 | 526191 | 531825 | Squirrel | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13920511 | FBXO44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neo plasms (ortholog); FOUND IN nucleus (ortholog) | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18396672 | FBXO44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN proteasomal protein catabolic process (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neo plasms (ortholog); FOUND IN nucleus (ortholog) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 329330687 | FBXO44 | F-box protein 44 | ENCODES a protein that exhibits ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN proteasomal protein catabolic process (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cyto plasm (inferred); nucleus (inferred); SCF ubiquitin ligase complex (inferred) | | | | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626176359 | fbxo44 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626177886 | fbxo44 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626180670 | fbxo44 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626182495 | fbxo44 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626185180 | fbxo44 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 1311861 | Fbxo45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN glutamatergic synapse (ortholo g); nucleoplasm (ortholog); postsynaptic cytosol (ortholog); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2,2',4,4'-Tetrabromodiphenyl ether (ortholog) | 11 | 82056457 | 82072080 | Rat | 84 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1349858 | FBXO45 | F-box protein 45 | Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Jan 2011] | 3 | 196568660 | 196589059 | Human | 74 | symbol , old_gene_name , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1553097 | Fbxo45 | F-box protein 45 | Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of synaptic vesicle exocytosis. Acts upstream of or within nervous system development. Located in postsynaptic d ensity. Is active in glutamatergic synapse; postsynaptic cytosol; and presynaptic cytosol. Is expressed in nervous system. Orthologous to human FBXO45 (F-box protein 45). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 32048930 | 32065843 | Mouse | 101 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9066734 | Fbxo45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN glutamatergic synapse (ortholo g); nucleoplasm (ortholog); postsynaptic cytosol (ortholog) | NW_004955420 | 12714749 | 12727600 | Chinchilla | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12122462 | FBXO45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN cytosol (inferred); glutamater gic synapse (inferred); nucleoplasm (inferred) | 33 | 29627762 | 29642175 | Dog | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12728793 | Fbxo45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN cytosol (inferred); glutamater gic synapse (inferred); nucleoplasm (inferred) | NW_004936784 | 1162950 | 1177407 | Squirrel | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14162305 | FBXO45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN cytosol (inferred); glutamater gic synapse (inferred); nucleoplasm (inferred) | | | | Pig | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18597601 | FBXO45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN cytosol (inferred); glutamater gic synapse (inferred); nucleoplasm (inferred) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936776 | Fbxo45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN glutamatergic synapse (ortholo g); nucleoplasm (ortholog); postsynaptic cytosol (ortholog) | | | | Naked Mole-Rat | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20420453 | FBXO45 | F-box protein 45 | | | | | Bonobo | | symbol | gene, protein-coding |
| 32732647 | FBXO45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN cytosol (inferred); glutamater gic synapse (inferred); nucleoplasm (inferred) | 3 | 193913712 | 193934123 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242877 | fbxo45 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626159904 | Fbxo45 | F-box protein 45 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN anterior commissure morphogenesis (ortholog); cerebral cortex radially oriented cell migration (ortholog); cerebral cortex tangential migration (ortholog); FOUND IN glutamatergic synapse (ortholo g); nucleoplasm (ortholog); postsynaptic cytosol (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1308393 | Fbxo46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodi oxine; 6-propyl-2-thiouracil | 1 | 87898029 | 87914615 | Rat | 57 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318136 | FBXO46 | F-box protein 46 | Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] | 19 | 45710629 | 45733177 | Human | 55 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1318137 | Fbxo46 | F-box protein 46 | Orthologous to human FBXO46 (F-box protein 46). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 18853784 | 18872186 | Mouse | 63 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8792510 | Fbxo46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | NW_004955574 | 177374 | 191720 | Chinchilla | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11872841 | FBXO46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | 19 | 42715616 | 42735949 | Bonobo | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12219934 | FBXO46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | 1 | 109863907 | 109878908 | Dog | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12652092 | Fbxo46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | NW_004936706 | 2080744 | 2095350 | Squirrel | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14283552 | FBXO46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | | | | Pig | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18382794 | FBXO46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN SCF ubiquitin ligase complex (inferred) | | | | Green Monkey | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934824 | Fbxo46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | | | | Naked Mole-Rat | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231423 | fbxo46 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626111768 | Fbxo46 | F-box protein 46 | ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog) | | | | Black Rat | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1559709 | Fbxo47 | F-box protein 47 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; paracetamol | 10 | 83331750 | 83376669 | Rat | 20 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1606618 | FBXO47 | F-box protein 47 | INTERACTS WITH benzo[a]pyrene; CGP 52608; lipopolysaccharide | 17 | 38936432 | 38967403 | Human | 21 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1623166 | Fbxo47 | F-box protein 47 | Orthologous to human FBXO47 (F-box protein 47). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 97741137 | 97775240 | Mouse | 31 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8766503 | Fbxo47 | F-box protein 47 | | NW_004955451 | 13939786 | 13967049 | Chinchilla | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12229004 | FBXO47 | F-box protein 47 | | 9 | 23310242 | 23337280 | Dog | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12615538 | Fbxo47 | F-box protein 47 | | NW_004936490 | 14311978 | 14331536 | Squirrel | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14115140 | FBXO47 | F-box protein 47 | | | | | Pig | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18570587 | FBXO47 | F-box protein 47 | | | | | Green Monkey | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922604 | Fbxo47 | F-box protein 47 | | | | | Naked Mole-Rat | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245339 | fbxo47 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 329345265 | FBXO47 | F-box protein 47 | | | | | Bonobo | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626124649 | Fbxo47 | F-box protein 47 | | | | | Black Rat | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1309073 | Fbxo48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred); INTERACTS WITH acetamide; bisphenol A; flutamide | 14 | 95582493 | 95583950 | Rat | 37 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319210 | Fbxo48 | F-box protein 48 | Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in axial skeleton; liver; midbrain ventricular layer; and telencephalon ventricular layer. Orth ologous to human FBXO48 (F-box protein 48). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 16901225 | 16908516 | Mouse | 40 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605751 | FBXO48 | F-box protein 48 | Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 68459422 | 68467294 | Human | 36 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 9058793 | Fbxo48 | F-box protein 48 | | NW_004955424 | 16449166 | 16455034 | Chinchilla | 1 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11980969 | FBXO48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | 2A | 68504304 | 68509113 | Bonobo | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12141194 | FBXO48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | 10 | 67449168 | 67453540 | Dog | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12518951 | Fbxo48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | NW_004936491 | 12854829 | 12857682 | Squirrel | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14086788 | FBXO48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | | | | Pig | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18767810 | FBXO48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910447 | Fbxo48 | F-box protein 48 | INVOLVED IN protein ubiquitination (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (inferred); SCF ubiquitin ligase complex (inferred) | | | | Naked Mole-Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284432080 | fbxo48 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 288081988 | fbxo40.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155237296 | fbxo41.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254021 | fbxo41.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155253618 | fbxo42.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259508 | fbxo42.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245869 | fbxo43.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155260037 | fbxo43.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248131 | fbxo45.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241092 | fbxo45.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155252097 | fbxo46.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155231424 | fbxo46.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469104 | fbxo48.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469170 | fbxo48.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1353624 | ECT2L | epithelial cell transforming 2 like | Predicted to enable guanyl-nucleotide exchange factor activity. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 138796087 | 138904070 | Human | 13 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11672353 | FBXO6 | F-box protein 6 | ENCODES a protein that exhibits carbohydrate binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN ERAD pathway (inferred); glycoprotein catabolic process (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH Stevens-J ohnson syndrome (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum quality control compartment (inferred); SCF ubiquitin ligase complex (inferred) | 1 | 10414856 | 10436406 | Bonobo | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913989 | LOC101722747 | F-box only protein 44 | ENCODES a protein that exhibits carbohydrate binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN ERAD pathway (inferred); glycoprotein catabolic process (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); FOUND IN cytoplasm (infer red); SCF ubiquitin ligase complex (inferred) | | | | Naked Mole-Rat | 12 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936357 | Smim8 | small integral membrane protein 8 | FOUND IN mitochondrion (ortholog) | | | | Naked Mole-Rat | 2 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
