Fbxo41 (F-box protein 41) - Rat Genome Database

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Gene: Fbxo41 (F-box protein 41) Mus musculus
Analyze
Symbol: Fbxo41
Name: F-box protein 41
RGD ID: 1557931
MGI Page MGI
Description: Is expressed in several structures, including forelimb bud; male reproductive gland or organ; nervous system; notochord; and sensory organ. Orthologous to human FBXO41 (F-box protein 41); INTERACTS WITH 4,4'-sulfonyldiphenol; chloroethene; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9630017H13; D6Ertd538; D6Ertd538e; F-box only protein 41
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,446,556 - 85,479,976 (-)NCBIGRCm39mm39
GRCm39 Ensembl685,446,556 - 85,479,976 (-)Ensembl
GRCm38685,469,574 - 85,502,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,469,574 - 85,502,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,419,572 - 85,452,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,436,185 - 85,468,652 (-)NCBImm8
Celera687,441,520 - 87,474,821 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14621295   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16452087  
PMID:17114649   PMID:21267068   PMID:22174793   PMID:24194600   PMID:26063905   PMID:26238476   PMID:27507650   PMID:27626380   PMID:28634551   PMID:28671696   PMID:29254152   PMID:31138677  
PMID:31160656   PMID:32581705  


Genomics

Comparative Map Data
Fbxo41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,446,556 - 85,479,976 (-)NCBIGRCm39mm39
GRCm39 Ensembl685,446,556 - 85,479,976 (-)Ensembl
GRCm38685,469,574 - 85,502,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,469,574 - 85,502,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,419,572 - 85,452,880 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,436,185 - 85,468,652 (-)NCBImm8
Celera687,441,520 - 87,474,821 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.48NCBI
FBXO41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl273,254,682 - 73,284,478 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl273,254,682 - 73,284,431 (-)EnsemblGRCh38hg38GRCh38
GRCh38273,254,690 - 73,284,478 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37273,481,818 - 73,511,606 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,335,308 - 73,351,551 (-)NCBINCBI36hg18NCBI36
Build 34273,394,603 - 73,408,251NCBI
Celera273,332,638 - 73,347,586 (-)NCBI
Cytogenetic Map2p13.2NCBI
HuRef273,217,469 - 73,232,417 (-)NCBIHuRef
CHM1_1273,412,617 - 73,427,565 (-)NCBICHM1_1
Fbxo41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24118,007,517 - 118,039,547 (-)NCBI
Rnor_6.0 Ensembl4117,256,770 - 117,268,178 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04117,255,143 - 117,285,228 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04181,832,758 - 181,861,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,725,853 - 119,740,162 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4106,991,380 - 107,020,972 (-)NCBICelera
Cytogenetic Map4q34NCBI
Fbxo41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,349,326 - 12,378,116 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,339,588 - 12,378,116 (+)NCBIChiLan1.0ChiLan1.0
FBXO41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A74,796,196 - 74,810,790 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,800,490 - 74,811,075 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A73,307,478 - 73,337,242 (-)NCBIMhudiblu_PPA_v0panPan3
FBXO41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,585,511 - 49,613,406 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,599,488 - 49,609,166 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1749,246,224 - 49,260,015 (+)NCBI
ROS_Cfam_1.01750,465,524 - 50,479,315 (+)NCBI
UMICH_Zoey_3.11749,481,830 - 49,495,621 (+)NCBI
UNSW_CanFamBas_1.01749,548,501 - 49,562,291 (+)NCBI
UU_Cfam_GSD_1.01750,107,680 - 50,121,471 (+)NCBI
Fbxo41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,500,082 - 11,535,289 (+)NCBI
SpeTri2.0NW_00493649117,035,988 - 17,048,165 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,496,651 - 69,525,845 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,496,527 - 69,525,854 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,699,383 - 72,729,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO41
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,904,062 - 33,919,470 (+)NCBI
ChlSab1.1 Ensembl1433,904,087 - 33,915,134 (+)Ensembl
Fbxo41
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624762360,168 - 386,642 (+)NCBI

Position Markers
AU022460  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38685,428,062 - 85,428,274UniSTSGRCm38
MGSCv37685,378,056 - 85,378,268UniSTSGRCm37
Celera687,400,008 - 87,400,220UniSTS
Cytogenetic Map6C3UniSTS
cM Map635.5UniSTS
Whitehead/MRC_RH6883.63UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4215
Count of miRNA genes:676
Interacting mature miRNAs:819
Transcripts:ENSMUST00000159062, ENSMUST00000161078, ENSMUST00000161546
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000159062   ⟹   ENSMUSP00000125671
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,469,574 - 85,502,994 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161078   ⟹   ENSMUSP00000124524
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,469,578 - 85,502,886 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161546   ⟹   ENSMUSP00000124754
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl685,469,580 - 85,502,858 (-)Ensembl
RefSeq Acc Id: NM_001001160   ⟹   NP_001001160
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,446,556 - 85,479,976 (-)NCBI
GRCm38685,469,574 - 85,502,994 (-)NCBI
MGSCv37685,419,572 - 85,452,880 (-)RGD
Celera687,441,516 - 87,474,929 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001289674   ⟹   NP_001276603
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,446,556 - 85,479,976 (-)NCBI
GRCm38685,469,574 - 85,502,994 (-)NCBI
Celera687,441,516 - 87,474,929 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289675   ⟹   NP_001276604
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,446,556 - 85,479,976 (-)NCBI
GRCm38685,469,574 - 85,502,994 (-)NCBI
Celera687,441,516 - 87,474,929 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001001160   ⟸   NM_001001160
- UniProtKB: Q6NS60 (UniProtKB/Swiss-Prot),   Q3UGY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276604   ⟸   NM_001289675
- UniProtKB: Q6NS60 (UniProtKB/Swiss-Prot),   Q3UGY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276603   ⟸   NM_001289674
- UniProtKB: Q6NS60 (UniProtKB/Swiss-Prot),   Q3UGY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000125671   ⟸   ENSMUST00000159062
RefSeq Acc Id: ENSMUSP00000124754   ⟸   ENSMUST00000161546
RefSeq Acc Id: ENSMUSP00000124524   ⟸   ENSMUST00000161078
Protein Domains
F-box

Promoters
RGD ID:6839296
Promoter ID:MM_KWN:46686
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_001001160,   OTTMUST00000072104,   UC009CPX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36685,452,871 - 85,453,371 (-)MPROMDB
RGD ID:6890234
Promoter ID:EPDNEW_M8568
Type:initiation region
Name:Fbxo41_1
Description:Mus musculus F-box protein 41 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38685,502,992 - 85,503,052EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1261912 AgrOrtholog
Ensembl Genes ENSMUSG00000047013 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000124524 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124754 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000125671 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000159062 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000161078 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000161546 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:330369 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1261912 ENTREZGENE
NCBI Gene 330369 ENTREZGENE
Pfam F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fbxo41 PhenoGen
Superfamily-SCOP SSF81383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FBX41_MOUSE UniProtKB/Swiss-Prot
  Q3UGY7 ENTREZGENE, UniProtKB/TrEMBL
  Q6NS60 ENTREZGENE
UniProt Secondary Q6P7W4 UniProtKB/Swiss-Prot
  Q6ZPG1 UniProtKB/Swiss-Prot