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Gene: Fbxo4 (F-box protein 4) Mus musculus
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Symbol: Fbxo4
Name: F-box protein 4
Description: Exhibits ubiquitin protein ligase activity. Involved in several processes, including common myeloid progenitor cell proliferation; positive regulation of protein polyubiquitination; and protein destabilization. Localizes to SCF ubiquitin ligase complex. Is expressed in several structures, including craniocervical region bone; esophagus; lung; pituitary gland; and sensory organ. Orthologous to human FBXO4 (F-box protein 4); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700096C12Rik; AI851261; AW494535; F-box only protein 4; Fbx4
Orthologs:
Homo sapiens (human) : FBXO4 (F-box protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo4 (F-box protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo4 (F-box protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO4 (F-box protein 4)
Canis lupus familiaris (dog) : FBXO4 (F-box protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo4 (F-box protein 4)
Sus scrofa (pig) : FBXO4 (F-box protein 4)
Chlorocebus sabaeus (African green monkey) : FBXO4 (F-box protein 4)
Heterocephalus glaber (naked mole-rat) : Fbxo4 (F-box protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl153,965,445 - 3,979,573 (-)EnsemblGRCm38mm10GRCm38
GRCm38153,963,564 - 3,979,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37153,913,564 - 3,929,573 (-)NCBIGRCm37mm9NCBIm37
MGSCv36153,915,461 - 3,929,573 (-)NCBImm8
Celera153,825,238 - 3,841,215 (-)NCBICelera
Cytogenetic Map15A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxo4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316857
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.