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Gene: Fbxo4 (F-box protein 4) Mus musculus
Symbol: Fbxo4
Name: F-box protein 4
Description: Exhibits ubiquitin protein ligase activity. Involved in several processes, including common myeloid progenitor cell proliferation; positive regulation of protein polyubiquitination; and protein destabilization. Localizes to SCF ubiquitin ligase complex. Is expressed in several structures, including craniocervical region bone; esophagus; lung; pituitary gland; and sensory organ. Orthologous to human FBXO4 (F-box protein 4); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700096C12Rik; AI851261; AW494535; F-box only protein 4; Fbx4
Homo sapiens (human) : FBXO4 (F-box protein 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo4 (F-box protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo4 (F-box protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO4 (F-box protein 4)
Canis lupus familiaris (dog) : FBXO4 (F-box protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo4 (F-box protein 4)
Sus scrofa (pig) : FBXO4 (F-box protein 4)
Chlorocebus sabaeus (African green monkey) : FBXO4 (F-box protein 4)
Heterocephalus glaber (naked mole-rat) : Fbxo4 (F-box protein 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl153,965,445 - 3,979,573 (-)EnsemblGRCm38mm10GRCm38
GRCm38153,963,564 - 3,979,573 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37153,913,564 - 3,929,573 (-)NCBIGRCm37mm9NCBIm37
MGSCv36153,915,461 - 3,929,573 (-)NCBImm8
Celera153,825,238 - 3,841,215 (-)NCBICelera
Cytogenetic Map15A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbxo4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316857
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.