FBXO6 (F-box protein 6) - Rat Genome Database

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Gene: FBXO6 (F-box protein 6) Pan paniscus
Analyze
Symbol: FBXO6 (Ensembl: FBXO44)
Name: F-box protein 6 (Ensembl:F-box protein 44)
RGD ID: 11672353
Description: ENCODES a protein that exhibits carbohydrate binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN ERAD pathway (inferred); glycoprotein catabolic process (inferred); SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); chromosome 1p36 deletion syndrome (ortholog); Familial Atrial Fibrillation 6 (ortholog); FOUND IN cytoplasm (inferred); endoplasmic reticulum quality control compartment (inferred); SCF ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 44; F-box only protein 6; F-box protein 44; FBXO44
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,414,856 - 10,436,406 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,632,724 - 11,641,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)NCBIpanpan1.1panPan2
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FBXO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,414,856 - 10,436,406 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,632,724 - 11,641,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)NCBIpanpan1.1panPan2
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensemblpanpan1.1panPan2
FBXO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,664,200 - 11,674,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,664,200 - 11,674,354 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,724,257 - 11,734,411 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,646,768 - 11,656,998 (+)NCBINCBI36Build 36hg18NCBI36
Build 34111,658,446 - 11,668,673NCBI
Celera110,836,207 - 10,846,475 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef110,878,308 - 10,888,516 (+)NCBIHuRef
CHM1_1111,712,136 - 11,722,413 (+)NCBICHM1_1
T2T-CHM13v2.0111,208,255 - 11,218,422 (+)NCBIT2T-CHM13v2.0
Fbxo44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,237,256 - 148,244,663 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,237,257 - 148,244,939 (-)EnsemblGRCm39 Ensembl
GRCm384148,152,799 - 148,160,183 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,152,800 - 148,160,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv374147,526,909 - 147,534,173 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364146,996,601 - 147,003,680 (-)NCBIMGSCv36mm8
Celera4150,414,144 - 150,420,371 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.67NCBI
Fbxo44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,866,517 - 163,875,928 (-)NCBIGRCr8
mRatBN7.25158,583,363 - 158,592,510 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,583,366 - 158,592,363 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5161,300,649 - 161,309,123 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05163,122,440 - 163,130,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05163,078,789 - 163,087,259 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,962,921 - 164,972,273 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,963,433 - 164,971,903 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,620,959 - 168,630,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,230,006 - 165,238,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5156,863,159 - 156,870,562 (-)NCBICelera
Cytogenetic Map5q36NCBI
Fbxo44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,204,470 - 2,210,604 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,204,470 - 2,210,604 (-)NCBIChiLan1.0ChiLan1.0
FBXO44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,557,468 - 84,562,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,089,720 - 81,095,293 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,220,535 - 85,225,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,220,537 - 85,225,672 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,969,300 - 81,974,662 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,970,031 - 82,975,586 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,032,774 - 84,038,260 (-)NCBIUU_Cfam_GSD_1.0
Fbxo44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,701,331 - 34,709,683 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936474525,862 - 532,152 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936474526,191 - 531,825 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,743,261 - 71,774,223 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,747,210 - 71,754,519 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,666,697 - 65,673,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,128,422 - 120,137,081 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,127,750 - 120,136,395 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605423,996,752 - 24,005,502 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,286,820 - 1,292,755 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248181,286,819 - 1,292,565 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003822078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003822079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008975611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034955529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000036057   ⟹   ENSPPAP00000013386
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036063   ⟹   ENSPPAP00000013392
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,632,768 - 11,640,846 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000050891   ⟹   ENSPPAP00000028047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl111,643,009 - 11,654,837 (+)Ensembl
RefSeq Acc Id: XM_034955416   ⟹   XP_034811307
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21216,550,354 - 216,557,625 (-)NCBI
NHGRI_mPanPan11215,196,499 - 215,209,566 (-)NCBI
Mhudiblu_PPA_v0110,423,103 - 10,436,081 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034811307 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028047.1
Reference Protein Sequences
RefSeq Acc Id: XP_034811307   ⟸   XM_034955416
- UniProtKB: A0A2R9BIE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028047   ⟸   ENSPPAT00000050891
RefSeq Acc Id: ENSPPAP00000013392   ⟸   ENSPPAT00000036063
RefSeq Acc Id: ENSPPAP00000013386   ⟸   ENSPPAT00000036057
Protein Domains
F-box   FBA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029865 Ensembl, ENTREZGENE
  ENSPPAG00000037077 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050891.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro F-box-assoc_dom UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_only UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
NCBI Gene FBXO44 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 6 UniProtKB/TrEMBL
  PTHR12125 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBA UniProtKB/TrEMBL
PROSITE FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
SMART FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
Superfamily-SCOP SSF49785 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A2R9BIE4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 FBXO6  F-box protein 6  FBXO44  F-box protein 44  Symbol and/or name change 5135510 APPROVED
2020-06-11 FBXO44  F-box protein 44  FBXO6  F-box protein 6  Data merged from RGD:11732955 737654 PROVISIONAL