Fbxo40 (F-box protein 40) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Fbxo40 (F-box protein 40) Ictidomys tridecemlineatus
Analyze
Symbol: Fbxo40
Name: F-box protein 40
RGD ID: 12570642
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN muscle cell differentiation (inferred); ASSOCIATED WITH alkaptonuria (ortholog); autistic disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box only protein 40; F-box protein 40, transcript variant X1; F-box protein 40, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,460,291 - 129,477,016 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,055,765 - 8,064,522 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,045,171 - 8,064,492 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxo40
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,460,291 - 129,477,016 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,055,765 - 8,064,522 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,045,171 - 8,064,492 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO40
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383121,593,379 - 121,630,295 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3121,593,379 - 121,630,295 (+)EnsemblGRCh38hg38GRCh38
GRCh373121,312,226 - 121,349,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363122,794,860 - 122,831,829 (+)NCBINCBI36Build 36hg18NCBI36
Build 343122,794,953 - 122,829,612NCBI
Celera3119,721,852 - 119,758,855 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3118,686,314 - 118,723,298 (+)NCBIHuRef
CHM1_13121,275,741 - 121,312,709 (+)NCBICHM1_1
T2T-CHM13v2.03124,313,284 - 124,350,193 (+)NCBIT2T-CHM13v2.0
Fbxo40
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391636,783,823 - 36,811,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1636,783,822 - 36,810,829 (-)EnsemblGRCm39 Ensembl
GRCm381636,963,461 - 36,990,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1636,963,460 - 36,990,467 (-)EnsemblGRCm38mm10GRCm38
MGSCv371636,966,159 - 36,979,222 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361636,885,312 - 36,898,375 (-)NCBIMGSCv36mm8
Celera1637,376,963 - 37,388,325 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.32NCBI
Fbxo40
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,299,826 - 77,318,086 (+)NCBIGRCr8
mRatBN7.21163,794,452 - 63,812,697 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1163,794,624 - 63,812,697 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01166,713,913 - 66,731,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,713,888 - 66,731,198 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01169,805,318 - 69,822,300 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,607,617 - 65,612,879 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,665,205 - 65,670,468 (+)NCBI
Celera1163,268,024 - 63,286,379 (+)NCBICelera
Cytogenetic Map11q21NCBI
Fbxo40
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542720,979,180 - 20,998,977 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542720,979,180 - 20,996,654 (+)NCBIChiLan1.0ChiLan1.0
FBXO40
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22119,550,057 - 119,588,185 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13119,554,834 - 119,592,962 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03118,695,215 - 118,730,183 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13125,604,930 - 125,639,658 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3125,604,930 - 125,639,658 (+)Ensemblpanpan1.1panPan2
FBXO40
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13324,841,998 - 24,899,973 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3324,880,530 - 24,897,129 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3324,869,274 - 24,926,898 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,084,229 - 25,142,217 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,122,484 - 25,142,217 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13324,882,504 - 24,940,457 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03324,924,936 - 24,982,927 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03325,481,797 - 25,540,040 (+)NCBIUU_Cfam_GSD_1.0
FBXO40
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13138,881,513 - 138,905,356 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113138,881,528 - 138,905,410 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213148,508,052 - 148,533,199 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO40
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12259,259,107 - 59,295,391 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2259,256,354 - 59,295,017 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041107,058,641 - 107,065,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo40
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473126,562,650 - 26,579,272 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473126,561,050 - 26,579,450 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000022938   ⟹   ENSSTOP00000023547
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365368,055,765 - 8,064,522 (+)Ensembl
RefSeq Acc Id: XM_013359713   ⟹   XP_013215167
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,460,291 - 129,477,016 (-)NCBI
SpeTri2.0NW_0049365368,045,199 - 8,064,492 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040270286   ⟹   XP_040126220
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602129,460,291 - 129,473,453 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013215167 (Get FASTA)   NCBI Sequence Viewer  
  XP_040126220 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023547.2
GenBank Protein KAG3271369 (Get FASTA)   NCBI Sequence Viewer  
  KAG3271370 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013215167   ⟸   XM_013359713
- UniProtKB: I3NGQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040126220   ⟸   XM_040270286
- UniProtKB: I3NGQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000023547   ⟸   ENSSTOT00000022938
Protein Domains
F-box   TRAF-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021524 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022938.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.30.40.150 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  Fbxo30/Fbxo40 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
  Znf_TRAF_N UniProtKB/TrEMBL
NCBI Gene Fbxo40 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 40 UniProtKB/TrEMBL
  PTHR15933 UniProtKB/TrEMBL
Pfam F-box_4 UniProtKB/TrEMBL
  zf-TRAF_2 UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
UniProt I3NGQ0 ENTREZGENE, UniProtKB/TrEMBL