Fgg (fibrinogen gamma chain) - Rat Genome Database

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Gene: Fgg (fibrinogen gamma chain) Rattus norvegicus
Analyze
Symbol: Fgg
Name: fibrinogen gamma chain
RGD ID: 2613
Description: Enables identical protein binding activity. Involved in cellular response to interleukin-1; cellular response to interleukin-6; and platelet maturation. Located in blood microparticle. Biomarker of obesity; pancreatitis; and pulmonary embolism. Human ortholog(s) of this gene implicated in brain small vessel disease; congenital afibrinogenemia; and multiple myeloma. Orthologous to human FGG (fibrinogen gamma chain); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: fibrinogen, gamma polypeptide
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   SS.MNS-(D2Chm25-Fgg)/Ayd  
QTLs:   Bp257  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,652,929 - 170,660,372 (+)NCBIGRCr8
mRatBN7.22168,354,880 - 168,362,325 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2168,355,013 - 168,362,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,545,169 - 175,552,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,566,102 - 173,573,404 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02168,167,520 - 168,174,818 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,987,080 - 181,994,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,987,217 - 181,994,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02201,401,700 - 201,409,143 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,727,312 - 174,734,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,677,417 - 174,684,698 (+)NCBI
Celera2162,381,731 - 162,389,018 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-Oleoyl-2-acetyl-sn-glycerol  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arachidonyl-2'-chloroethylamide  (ISO)
aristolochic acids  (EXP)
Azaspiracid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
calcium silicate  (ISO)
carbon nanotube  (EXP,ISO)
carnosic acid  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chlorpyrifos  (ISO)
chromium trinitrate  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
dabigatran  (ISO)
dibenz[a,h]anthracene  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dienogest  (ISO)
diethyl maleate  (ISO)
diisopropyl fluorophosphate  (EXP)
dimethyl sulfoxide  (EXP)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
elemental selenium  (EXP)
endosulfan  (EXP)
fenofibrate  (EXP)
fenthion  (ISO)
fructose  (ISO)
furan  (EXP)
gemcitabine  (ISO)
gestodene  (ISO)
glucose  (ISO)
glyphosate  (ISO)
graphene oxide  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
inulin  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
levonorgestrel  (ISO)
malathion  (ISO)
menadione  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
natamycin  (ISO)
nefazodone  (EXP)
nitrofen  (EXP)
norethisterone  (ISO)
norgestimate  (ISO)
nystatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl caffeate  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
quartz  (EXP)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
selenium atom  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
titanium dioxide  (EXP,ISO)
tremolite asbestos  (ISO)
tributylstannane  (ISO)
Triptolide  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vitamin E  (EXP)
vitamin K  (EXP)
XAV939  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Hepatic fibrinogen storage disease: identification of two novel mutations (p.Asp316Asn, fibrinogen Pisa and p.Gly366Ser, fibrinogen Beograd) impacting on the fibrinogen gamma-module. Asselta R, etal., J Thromb Haemost. 2015 Aug;13(8):1459-67. doi: 10.1111/jth.13021. Epub 2015 Jul 14.
2. Molecular characterization of 7 patients affected by dys- or hypo-dysfibrinogenemia: Identification of a novel mutation in the fibrinogen Bbeta chain causing a gain of glycosylation. Asselta R, etal., Thromb Res. 2015 Jul;136(1):168-74. doi: 10.1016/j.thromres.2015.05.007. Epub 2015 May 14.
3. Novel fibrinogen gamma375 Arg-->Trp mutation (fibrinogen aguadilla) causes hepatic endoplasmic reticulum storage and hypofibrinogenemia. Brennan SO, etal., Hepatology. 2002 Sep;36(3):652-8.
4. Abnormal expression of Smurf2 during the process of rat liver fibrosis. Cai Y, etal., Chin J Dig Dis. 2006;7(4):237-45.
5. Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study. Carty CL, etal., Thromb Haemost. 2008 Feb;99(2):388-95.
6. Quantitative organellar proteomics analysis of rough endoplasmic reticulum from normal and acute pancreatitis rat pancreas. Chen X, etal., J Proteome Res. 2010 Feb 5;9(2):885-96.
7. Profiling of gender-specific rat plasma proteins associated with susceptibility or resistance to diet-induced obesity. Choi JW, etal., J Proteomics. 2012 Feb 2;75(4):1386-400. doi: 10.1016/j.jprot.2011.11.012. Epub 2011 Nov 20.
8. Developmental expression of mRNAs encoding platelet proteins in rat megakaryocytes. Courtney MA, etal., Blood. 1991 Feb 1;77(3):560-8.
9. Organization of the rat gamma-fibrinogen gene: alternative mRNA splice patterns produce the gamma A and gamma B (gamma ') chains of fibrinogen. Crabtree GR and Kant JA, Cell 1982 Nov;31(1):159-66.
10. [Comparative plasma proteomic analysis of patients with multiple myeloma treated with bortezomib-based regimens]. Cumova J, etal., Klin Onkol. 2012;25(1):17-25.
11. Mapping of a quantitative trait locus for blood pressure on rat chromosome 2. Deng AY, etal., J Clin Invest 1994 Jul;94(1):431-6
12. Mapping of rat chromosome 2 markers generated from chromosome-sorted DNA. Deng AY, etal., Mamm Genome 1997 Oct;8(10):731-5.
13. Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions. Fowlkes DM, etal., Proc Natl Acad Sci U S A 1984 Apr;81(8):2313-6.
14. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
15. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
16. Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. Gralinski LE, etal., mBio. 2013 Aug 6;4(4). pii: mBio.00271-13. doi: 10.1128/mBio.00271-13.
17. Identification of a novel splicing mutation in the fibrinogen gamma chain gene leading to dysfibrinogenaemia in a Chinese pedigree. Huang D, etal., Pathology. 2015 Feb;47(2):145-50. doi: 10.1097/PAT.0000000000000213.
18. Haemostatic abnormalities persist despite glycaemic improvement by insulin therapy in lean type 2 diabetic patients. Knobl P, etal., Thromb Haemost. 1994 Jun;71(6):692-7.
19. Fibrinogen beta-derived Bbeta(15-42) peptide protects against kidney ischemia/reperfusion injury. Krishnamoorthy A, etal., Blood. 2011 Aug 18;118(7):1934-42. Epub 2011 Jun 17.
20. Improved radiation hybrid map of rat chromosome 2: colocalization of the genes encoding corticotropin-releasing hormone and IL6-receptor with quantitative trait loci regulating the inflammatory response. Laes JF, etal., Cytogenet Cell Genet 2001;92(1-2):130-3.
21. ICAM1 and fibrinogen-gamma are increased in uterine epithelial cells at the time of implantation in rats. Lecce L, etal., Mol Reprod Dev. 2011 May;78(5):318-27. doi: 10.1002/mrd.21307. Epub 2011 Mar 29.
22. Fibrinogen Hangzhou: congenital dysfibrinogenemia caused by the novel missense mutation in FGG (gamma308Asn-->Thr). Liao Z, etal., Clin Chim Acta. 2014 Jan 20;428:106-9.
23. Basic mechanisms and regulation of fibrinolysis. Longstaff C and Kolev K, J Thromb Haemost. 2015 Jun;13 Suppl 1:S98-105. doi: 10.1111/jth.12935.
24. A G-to-A mutation in IVS-3 of the human gamma fibrinogen gene causing afibrinogenemia due to abnormal RNA splicing. Margaglione M, etal., Blood 2000 Oct 1;96(7):2501-5.
25. Novel fibrinogen mutation (gamma 313 Ser-->Asn) associated with hypofibrinogenemia in two unrelated families. Meyer M, etal., Blood Coagul Fibrinolysis. 2006 Jan;17(1):63-7.
26. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
27. Nucleotide sequence of the gamma chain gene of rat fibrinogen: conserved intronic sequences. Morgan JG, etal., Nucleic Acids Res 1987 Mar 25;15(6):2774-6.
28. Fibrinogen and fibrin structure and functions. Mosesson MW J Thromb Haemost. 2005 Aug;3(8):1894-904.
29. Plasma fibrinogen gamma' chain content in the thrombotic microangiopathy syndrome. Mosesson MW, etal., J Thromb Haemost. 2007 Jan;5(1):62-9. Epub 2006 Oct 13.
30. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
31. Expression and analysis of a split premature termination codon in FGG responsible for congenital afibrinogenemia: escape from RNA surveillance mechanisms in transfected cells. Neerman-Arbez M, etal., Blood. 2004 Dec 1;104(12):3618-23. Epub 2004 Jul 29.
32. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
33. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
34. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
35. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
36. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
37. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
38. Comprehensive gene review and curation RGD comprehensive gene curation
39. The responses of rat liver glucocorticoid receptors and genes for tyrosine aminotransferase, alpha-2-macroglobulin and gamma-fibrinogen to adrenalectomy-, dexamethasone- and inflammation-induced changes in the levels of glucocorticoids and proinflammatory cytokines. Sevaljevic L, etal., Biol Signals Recept. 2001 Sep-Oct;10(5):299-309.
40. Fibrinogen Seoul (FGG Ala341Asp): a novel mutation associated with hypodysfibrinogenemia. Song KS, etal., Clin Appl Thromb Hemost. 2006 Jul;12(3):338-43.
41. Molecular basis of quantitative fibrinogen disorders in 27 patients from India. Sumitha E, etal., Haemophilia. 2013 Jul;19(4):611-8. doi: 10.1111/hae.12143. Epub 2013 Apr 8.
42. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
43. Ability of fibrinogen gamma-derived dodecapeptides with different sequences to bind to rat platelets. Tokutomi K, etal., Int J Pharm. 2012 Nov 15;438(1-2):296-301. doi: 10.1016/j.ijpharm.2012.09.016. Epub 2012 Sep 15.
44. Proteomic analysis of plasma from rats following total parenteral nutrition-induced liver injury. Tsai JJ, etal., Proteomics. 2015 Nov;15(22):3865-74. doi: 10.1002/pmic.201500128.
45. Haplotypes of the fibrinogen gene and cerebral small vessel disease: the Rotterdam scan study. van Oijen M, etal., J Neurol Neurosurg Psychiatry. 2008 Jul;79(7):799-803. Epub 2007 Oct 19.
46. Proteomics of microparticles after experimental pulmonary embolism. Watts JA, etal., Thromb Res. 2011 Oct 17.
47. Interleukin 1beta inhibits interleukin 6-mediated rat gamma fibrinogen gene expression. Zhang Z and Fuller GM, Blood 2000 Nov 15;96(10):3466-72.
48. A novel fibrinogen mutation (gamma Thr277Arg) causes hereditary hypofibrinogenemia in a Chinese family. Zhu L, etal., Blood Coagul Fibrinolysis. 2013 Sep;24(6):642-4. doi: 10.1097/MBC.0b013e32835facdc.
49. Novel mutations (gammaTrp208Leu and gammaLys232Thr) leading to congenital hypofibrinogenemia in two unrelated Chinese families. Zhu L, etal., Blood Coagul Fibrinolysis. 2014 Dec;25(8):894-7. doi: 10.1097/MBC.0000000000000156.
Additional References at PubMed
PMID:6281794   PMID:6451630   PMID:6777381   PMID:7822297   PMID:8100742   PMID:8470043   PMID:8910396   PMID:10903502   PMID:11001902   PMID:12477932   PMID:12706644   PMID:15489334  
PMID:15739255   PMID:15914557   PMID:16452087   PMID:16502470   PMID:16846481   PMID:18676163   PMID:19056867   PMID:19193866   PMID:22206666   PMID:22516433   PMID:23376485   PMID:23533145  
PMID:24414074  


Genomics

Comparative Map Data
Fgg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82170,652,929 - 170,660,372 (+)NCBIGRCr8
mRatBN7.22168,354,880 - 168,362,325 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2168,355,013 - 168,362,322 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2175,545,169 - 175,552,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02173,566,102 - 173,573,404 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02168,167,520 - 168,174,818 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,987,080 - 181,994,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,987,217 - 181,994,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02201,401,700 - 201,409,143 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,727,312 - 174,734,594 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12174,677,417 - 174,684,698 (+)NCBI
Celera2162,381,731 - 162,389,018 (+)NCBICelera
Cytogenetic Map2q34NCBI
FGG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384154,604,136 - 154,612,656 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4154,604,134 - 154,612,967 (-)EnsemblGRCh38hg38GRCh38
GRCh374155,525,288 - 155,533,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364155,744,736 - 155,753,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 344155,883,339 - 155,891,408NCBI
Celera4152,856,249 - 152,864,865 (-)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4151,265,862 - 151,274,478 (-)NCBIHuRef
CHM1_14155,503,216 - 155,511,832 (-)NCBICHM1_1
T2T-CHM13v2.04157,935,943 - 157,944,463 (-)NCBIT2T-CHM13v2.0
Fgg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39382,915,031 - 82,922,363 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl382,915,031 - 82,922,356 (+)EnsemblGRCm39 Ensembl
GRCm38383,007,724 - 83,015,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl383,007,724 - 83,015,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv37382,811,818 - 82,818,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36383,093,823 - 83,100,976 (+)NCBIMGSCv36mm8
Celera383,011,995 - 83,019,099 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map336.94NCBI
Fgg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554718,786,910 - 8,795,013 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554718,786,910 - 8,794,947 (+)NCBIChiLan1.0ChiLan1.0
FGG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23152,516,571 - 152,539,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14152,872,009 - 152,886,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04146,970,671 - 146,979,348 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14158,788,761 - 158,797,460 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4158,788,966 - 158,797,237 (-)Ensemblpanpan1.1panPan2
FGG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11552,261,215 - 52,270,077 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1552,261,217 - 52,269,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1552,605,731 - 52,614,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01552,948,278 - 52,957,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1552,948,283 - 52,957,026 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11552,203,172 - 52,211,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01552,307,741 - 52,316,537 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01552,622,568 - 52,631,351 (-)NCBIUU_Cfam_GSD_1.0
Fgg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530138,194,766 - 38,203,257 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365761,343,661 - 1,352,143 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365761,343,657 - 1,352,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl874,553,105 - 74,563,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1874,553,040 - 74,562,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,850,804 - 78,859,881 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17101,148,457 - 101,157,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7101,148,058 - 101,157,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603780,803,057 - 80,811,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248585,827,316 - 5,838,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248585,828,334 - 5,836,382 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fgg
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:16
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000034521
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat

Markers in Region
D2Mit12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,358,098 - 168,358,342 (+)MAPPERmRatBN7.2
Rnor_6.02181,990,297 - 181,990,540NCBIRnor6.0
Rnor_5.02201,404,917 - 201,405,160UniSTSRnor5.0
RGSC_v3.42174,730,375 - 174,730,618UniSTSRGSC3.4
Celera2162,384,792 - 162,385,042UniSTS
RH 3.4 Map21094.5RGD
RH 3.4 Map21094.5UniSTS
FHH x ACI Map275.4999UniSTS
FHH x ACI Map275.4999RGD
Cytogenetic Map2q31-q34UniSTS
D2Wox17  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,358,200 - 168,358,343 (+)MAPPERmRatBN7.2
Rnor_6.02181,990,399 - 181,990,541NCBIRnor6.0
Rnor_5.02201,405,019 - 201,405,161UniSTSRnor5.0
RGSC_v3.42174,730,476 - 174,730,619RGDRGSC3.4
RGSC_v3.42174,730,477 - 174,730,619UniSTSRGSC3.4
RGSC_v3.12174,680,582 - 174,680,725RGD
Celera2162,384,894 - 162,385,043UniSTS
RH 3.4 Map21098.6UniSTS
RH 3.4 Map21098.6RGD
RH 2.0 Map2765.0RGD
Cytogenetic Map2q31-q34UniSTS
D2Wox18  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,355,132 - 168,355,276 (+)MAPPERmRatBN7.2
Rnor_6.02181,987,333 - 181,987,474NCBIRnor6.0
Rnor_5.02201,401,953 - 201,402,094UniSTSRnor5.0
RGSC_v3.42174,727,410 - 174,727,552RGDRGSC3.4
RGSC_v3.42174,727,411 - 174,727,552UniSTSRGSC3.4
RGSC_v3.12174,677,516 - 174,677,658RGD
Celera2162,381,830 - 162,381,969UniSTS
RH 3.4 Map21098.7UniSTS
RH 3.4 Map21098.7RGD
RH 2.0 Map2764.4RGD
Cytogenetic Map2q31-q34UniSTS
D2Arb12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,358,132 - 168,358,402 (+)MAPPERmRatBN7.2
Rnor_6.02181,990,331 - 181,990,600NCBIRnor6.0
Rnor_5.02201,404,951 - 201,405,220UniSTSRnor5.0
RGSC_v3.42174,730,408 - 174,730,678RGDRGSC3.4
RGSC_v3.42174,730,409 - 174,730,678UniSTSRGSC3.4
RGSC_v3.12174,680,514 - 174,680,784RGD
Celera2162,384,826 - 162,385,102UniSTS
RH 3.4 Map21098.7UniSTS
RH 3.4 Map21098.7RGD
FHH x ACI Map275.4199UniSTS
FHH x ACI Map275.4199RGD
Cytogenetic Map2q31-q34UniSTS
RH127613  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,361,936 - 168,362,154 (+)MAPPERmRatBN7.2
Rnor_6.02181,994,135 - 181,994,352NCBIRnor6.0
Rnor_5.02201,408,755 - 201,408,972UniSTSRnor5.0
RGSC_v3.42174,734,213 - 174,734,430UniSTSRGSC3.4
Celera2162,388,637 - 162,388,854UniSTS
RH 3.4 Map21098.7UniSTS
Cytogenetic Map2q31-q34UniSTS
RH137153  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,361,582 - 168,361,791 (+)MAPPERmRatBN7.2
Rnor_6.02181,993,781 - 181,993,989NCBIRnor6.0
Rnor_5.02201,408,401 - 201,408,609UniSTSRnor5.0
RGSC_v3.42174,733,859 - 174,734,067UniSTSRGSC3.4
Celera2162,388,283 - 162,388,491UniSTS
RH 3.4 Map21097.0UniSTS
Cytogenetic Map2q31-q34UniSTS
d2mit12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22168,358,098 - 168,358,343 (+)MAPPERmRatBN7.2
Rnor_6.02181,990,297 - 181,990,541NCBIRnor6.0
Rnor_5.02201,404,917 - 201,405,161UniSTSRnor5.0
RGSC_v3.42174,730,375 - 174,730,619UniSTSRGSC3.4
Celera2162,384,792 - 162,385,043UniSTS
Cytogenetic Map2q31-q34UniSTS


Related Rat Strains
The following Strains have been annotated to Fgg
SS.MNS-(D2Chm25-Fgg)/Ayd    


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 31 31 31
Medium 12 10 10 2 2 10 11 2
Low 16 14 17 6 6 41 35 29 6
Below cutoff 2 20 2 2 33 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC078893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J00733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J00734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J00735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K01337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X05860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X05861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000034521   ⟹   ENSRNOP00000032735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2168,355,013 - 168,362,322 (+)Ensembl
Rnor_6.0 Ensembl2181,987,217 - 181,994,514 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115976   ⟹   ENSRNOP00000082495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2168,355,013 - 168,361,908 (+)Ensembl
RefSeq Acc Id: NM_012559   ⟹   NP_036691
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82170,653,083 - 170,660,365 (+)NCBI
mRatBN7.22168,355,034 - 168,362,318 (+)NCBI
Rnor_6.02181,987,234 - 181,994,516 (+)NCBI
Rnor_5.02201,401,700 - 201,409,143 (+)NCBI
RGSC_v3.42174,727,312 - 174,734,594 (+)RGD
Celera2162,381,731 - 162,389,018 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232525   ⟹   XP_006232587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82170,652,929 - 170,660,372 (+)NCBI
mRatBN7.22168,354,880 - 168,362,325 (+)NCBI
Rnor_6.02181,987,080 - 181,994,523 (+)NCBI
Rnor_5.02201,401,700 - 201,409,143 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_036691   ⟸   NM_012559
- Peptide Label: precursor
- UniProtKB: A6J5U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232587   ⟸   XM_006232525
- Peptide Label: isoform X1
- UniProtKB: Q68FY3 (UniProtKB/Swiss-Prot),   P02680 (UniProtKB/Swiss-Prot),   A6J5U8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032735   ⟸   ENSRNOT00000034521
RefSeq Acc Id: ENSRNOP00000082495   ⟸   ENSRNOT00000115976
Protein Domains
Fibrinogen C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P02680-F1-model_v2 AlphaFold P02680 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691395
Promoter ID:EPDNEW_R1920
Type:single initiation site
Name:Fgg_1
Description:fibrinogen gamma chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02181,987,214 - 181,987,274EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2613 AgrOrtholog
BioCyc Gene G2FUF-52663 BioCyc
Ensembl Genes ENSRNOG00000025074 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055021991 UniProtKB/Swiss-Prot
  ENSRNOG00060007361 UniProtKB/Swiss-Prot
  ENSRNOG00065030932 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000034521 ENTREZGENE
  ENSRNOT00000034521.7 UniProtKB/Swiss-Prot
  ENSRNOT00000115976 ENTREZGENE
  ENSRNOT00000115976.1 UniProtKB/Swiss-Prot
  ENSRNOT00055037761 UniProtKB/Swiss-Prot
  ENSRNOT00060012122 UniProtKB/Swiss-Prot
  ENSRNOT00065053321 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.215.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122366 IMAGE-MGC_LOAD
InterPro Fibrinogen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_a/b/g_coil_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24367 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93618 IMAGE-MGC_LOAD
NCBI Gene 24367 ENTREZGENE
PANTHER FIBRINOGEN ALPHA CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FIBRINOGEN GAMMA CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Fib_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibrinogen_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgg PhenoGen
PROSITE FIBRINOGEN_C_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025074 RatGTEx
  ENSRNOG00055021991 RatGTEx
  ENSRNOG00060007361 RatGTEx
  ENSRNOG00065030932 RatGTEx
SMART FBG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fib_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Fibrinogen C-terminal domain-like UniProtKB/TrEMBL
  Fibrinogen coiled-coil and central regions UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56496 UniProtKB/Swiss-Prot
TIGR TC219093
UniProt A6J5U7 ENTREZGENE, UniProtKB/TrEMBL
  A6J5U8 ENTREZGENE, UniProtKB/TrEMBL
  FIBG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q68FY3 ENTREZGENE
UniProt Secondary Q68FY3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Fgg  fibrinogen gamma chain  Fgg  fibrinogen, gamma polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Fgg  Fibrinogen, gamma polypeptide      Symbol and Name status set to approved 70586 APPROVED