Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:extracellular exosome biogenesis
go back to main search page
Accession:GO:0097734 term browser browse the term
Definition:The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
Synonyms:exact_synonym: exosome assembly or secretion;   exosome biogenesis;   exosome production
 related_synonym: ILV assembly;   intraluminal vesicle assembly

show annotations for term's descendants           Sort by:
 
extracellular exosome biogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO (PMID:25392495) RGD PMID:25392495 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637 		JBrowse link
exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops5 COP9 signalosome subunit 5 involved_in ISO (PMID:19246649) RGD PMID:19246649 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family involved_in ISO (PMID:15634213) RGD PMID:15634213 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family involved_in ISO (PMID:23092844) RGD PMID:23092844 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (MGI:4367682|PMID:18617898) RGD PMID:18617898 MGI:4367682 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (MGI:5770036|PMID:25392495) RGD PMID:25392495 MGI:5770036 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950 		JBrowse link
extracellular exosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISO
ISS		 (PMID:21835908)
GO_REF:0000024		 RGD
UniProt		 PMID:21835908 GO_REF:0000024 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647 		JBrowse link
negative regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp9a ATPase phospholipid transporting 9A (putative) involved_in ISO
IEA		 (PMID:30947313)
GO_REF:0000107		 RGD
Ensembl		 PMID:30947313 GO_REF:0000107 NCBI chr 3:165,405,588...165,511,104
Ensembl chr 3:165,412,803...165,477,771 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:26911690) RGD PMID:26911690 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:26911690) RGD PMID:26911690 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460 		JBrowse link
positive regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a2 ATPase cation transporting 13A2 involved_in ISO (PMID:24603074), (PMID:25392495)
(MGI:5770036|PMID:25392495)		 RGD PMID:24603074 PMID:25392495 MGI:5770036 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637 		JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr10:109,638,944...109,657,460
Ensembl chr10:109,638,767...109,657,456 		JBrowse link
G Myo5b myosin Vb IMP RGD PMID:18984164 RGD:11533643 NCBI chr18:70,426,865...70,729,985
Ensembl chr18:70,427,007...70,729,030 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173 		JBrowse link
G Sdc1 syndecan 1 involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016 		JBrowse link
G Sdc4 syndecan 4 involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in IMP PMID:24743145 BHF-UCL PMID:24743145 RGD:10054083 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528 		JBrowse link
G Snf8 SNF8 subunit of ESCRT-II involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr10:83,856,331...83,868,621
Ensembl chr10:83,856,280...83,868,598 		JBrowse link
G Stam signal transducing adaptor molecule involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:22660413), (PMID:24105262) RGD PMID:22660413 PMID:24105262 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO UniProtKB:O75351 (PMID:22660413) RGD PMID:22660413 NCBI chr19:39,230,050...39,243,298
Ensembl chr19:39,229,754...39,243,496 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO UniProtKB:Q9UN37 (PMID:22660413) RGD PMID:22660413 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460 		JBrowse link
positive regulation of extracellular exosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125 		JBrowse link
G Sdc1 syndecan 1 involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016 		JBrowse link
G Sdc4 syndecan 4 involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190 		JBrowse link
G Sdcbp syndecan binding protein involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485 		JBrowse link
regulation of exosomal secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chmp3 charged multivesicular body protein 3 NOT|involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423 		JBrowse link
G Chmp6 charged multivesicular body protein 6 NOT|involved_in ISO (PMID:22660413) RGD PMID:22660413 NCBI chr10:109,073,678...109,079,348
Ensembl chr10:109,073,678...109,079,348 		JBrowse link
regulation of extracellular exosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125 		JBrowse link
G Stam signal transducing adaptor molecule involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr17:81,209,795...81,256,111
Ensembl chr17:81,209,867...81,255,808 		JBrowse link
G Tsg101 tumor susceptibility 101 involved_in ISO (PMID:24105262) RGD PMID:24105262 NCBI chr 1:102,941,151...102,971,017
Ensembl chr 1:102,941,231...102,970,950 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19633
    cellular process 18481
      cellular component organization or biogenesis 6709
        cellular component biogenesis 3276
          extracellular vesicle biogenesis 26
            extracellular exosome biogenesis 24
              exosomal secretion + 23
              extracellular exosome assembly + 7
paths to the root