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ONTOLOGY REPORT - ANNOTATIONS

Term:attachment of mitotic spindle microtubules to kinetochore
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Accession:GO:0051315 term browser browse the term
Definition:The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
Comment:This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation)
Synonyms:exact_synonym: attachment of spindle microtubules to kinetochore involved in mitosis;   attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation;   attachment of spindle microtubules to mitotic chromosome
 related_synonym: attachment of spindle microtubules to kinetochore during mitosis;   mitotic bipolar attachment
 alt_id: GO:0051314


show annotations for term's descendants           Sort by:
 
attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Cenpc centromere protein C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) RGD PMID:15843429 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in ISO
IBA		 (PMID:21063390)
PMID:21873635		 RGD PMID:21063390 PMID:21873635 RGD:13792537 NCBI chr16:75,733,958...75,744,977
Ensembl chr16:75,733,805...75,744,984 		JBrowse link
G Kif2c kinesin family member 2C involved_in ISO
ISS
IEA		 (PMID:23891108)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:23891108 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23001180)		 UniProt
RGD		 PMID:23001180 GO_REF:0000024 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in ISO
ISS		 (PMID:23891108)
GO_REF:0000024		 RGD
UniProt		 PMID:23891108 GO_REF:0000024 NCBI chr10:55,739,590...55,747,915
Ensembl chr10:55,739,564...55,751,068 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO
IEA		 (PMID:23891108), (PMID:25743205)
GO_REF:0000104
(PMID:23891108), (PMID:25743205), (PMID:30409912)		 RGD
UniProt		 PMID:23891108 PMID:25743205 PMID:30409912 GO_REF:0000104 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:17363900) RGD PMID:17363900
lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:23891108) RGD PMID:23891108 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
mitotic sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248), (PMID:24157919) RGD PMID:17938248 PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787 		JBrowse link
positive regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in ISO (PMID:23478334) RGD PMID:23478334 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IBA
IEA
ISO
ISS		 PMID:21873635
GO_REF:0000107
(PMID:21242313)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21242313 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:23001180) RGD PMID:23001180 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO
ISS		 (PMID:30409912)
GO_REF:0000024		 RGD
UniProt		 PMID:30409912 GO_REF:0000024 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO (PMID:28751710) RGD PMID:28751710 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cell cycle process 1244
        mitotic cell cycle process 760
          attachment of mitotic spindle microtubules to kinetochore 17
            lateral attachment of mitotic spindle microtubules to kinetochore + 2
            mitotic sister chromatid biorientation + 1
            negative regulation of attachment of mitotic spindle microtubules to kinetochore 0
            positive regulation of attachment of mitotic spindle microtubules to kinetochore + 5
            regulation of attachment of mitotic spindle microtubules to kinetochore + 5
Path 2
Term Annotations click to browse term
  biological_process 20094
    cellular process 18691
      cellular component organization or biogenesis 6758
        cellular component organization 6506
          organelle organization 3660
            organelle fission 528
              nuclear division 475
                mitotic nuclear division 303
                  mitotic sister chromatid segregation 175
                    mitotic metaphase plate congression 54
                      attachment of mitotic spindle microtubules to kinetochore 17
                        lateral attachment of mitotic spindle microtubules to kinetochore + 2
                        mitotic sister chromatid biorientation + 1
                        negative regulation of attachment of mitotic spindle microtubules to kinetochore 0
                        positive regulation of attachment of mitotic spindle microtubules to kinetochore + 5
                        regulation of attachment of mitotic spindle microtubules to kinetochore + 5
paths to the root