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ONTOLOGY REPORT - ANNOTATIONS


Term:attachment of mitotic spindle microtubules to kinetochore
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Accession:GO:0051315 term browser browse the term
Definition:The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.
Comment:This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation)
Synonyms:exact_synonym: attachment of spindle microtubules to kinetochore involved in mitosis;   attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation;   attachment of spindle microtubules to mitotic chromosome
 related_synonym: attachment of spindle microtubules to kinetochore during mitosis;   mitotic bipolar attachment
 alt_id: GO:0051314



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attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cenpc centromere protein C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) RGD PMID:15843429 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in ISO
IBA
(PMID:21063390)
GO_REF:0000033
RGD
GO_Central
PMID:21063390 GO_REF:0000033 NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984
JBrowse link
G Kif2c kinesin family member 2C involved_in ISO
ISS
IEA
(PMID:23891108)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:23891108 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:23001180)
UniProt
Ensembl
RGD
PMID:23001180 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in ISO
IEA
ISS
(PMID:23891108)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23891108 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO
IBA
(PMID:22581055), (PMID:23891108), (PMID:25743205), (PMID:30409912)
GO_REF:0000033
RGD
GO_Central
PMID:22581055 PMID:23891108 PMID:25743205 PMID:30409912 GO_REF:0000033 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:17363900) RGD PMID:17363900 NCBI chr18:61,346,986...61,369,987 JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:29487209)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29487209 GO_REF:0000024 GO_REF:0000107 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:29487209)
UniProt
RGD
PMID:29487209 GO_REF:0000024 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29487209)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29487209 GO_REF:0000024 GO_REF:0000107 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
JBrowse link
lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:23891108) RGD PMID:23891108 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
mitotic sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248), (PMID:24157919) RGD PMID:17938248 PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
negative regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 involved_in ISO (PMID:30409912) RGD PMID:30409912 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
positive regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in ISO (PMID:23478334) RGD PMID:23478334 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:21242313)
GO_REF:0000024
GO_REF:0000118
Ensembl
RGD
UniProt
TreeGrafter
PMID:21242313 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:23001180) RGD PMID:23001180 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO
ISS
IEA
(PMID:30409912)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:30409912 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO
IEA
(PMID:28751710)
GO_REF:0000107
RGD
Ensembl
PMID:28751710 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cell cycle process 1345
        mitotic cell cycle process 767
          attachment of mitotic spindle microtubules to kinetochore 21
            lateral attachment of mitotic spindle microtubules to kinetochore + 2
            mitotic sister chromatid biorientation + 1
            negative regulation of attachment of mitotic spindle microtubules to kinetochore 1
            positive regulation of attachment of mitotic spindle microtubules to kinetochore + 5
            regulation of attachment of mitotic spindle microtubules to kinetochore + 6
Path 2
Term Annotations click to browse term
  biological_process 20328
    cellular process 18788
      cellular component organization or biogenesis 7188
        cellular component organization 6877
          organelle organization 3816
            organelle fission 536
              nuclear division 477
                mitotic nuclear division 277
                  mitotic sister chromatid segregation 185
                    mitotic metaphase chromosome alignment 58
                      attachment of mitotic spindle microtubules to kinetochore 21
                        lateral attachment of mitotic spindle microtubules to kinetochore + 2
                        mitotic sister chromatid biorientation + 1
                        negative regulation of attachment of mitotic spindle microtubules to kinetochore 1
                        positive regulation of attachment of mitotic spindle microtubules to kinetochore + 5
                        regulation of attachment of mitotic spindle microtubules to kinetochore + 6
paths to the root