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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic metaphase chromosome alignment
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Accession:GO:0007080 term browser browse the term
Definition:A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.



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mitotic metaphase chromosome alignment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd53 ankyrin repeat domain 53 involved_in ISO
IBA
(PMID:26820536)
GO_REF:0000033
RGD
GO_Central
PMID:26820536 GO_REF:0000033 NCBI chr 4:116,245,561...116,253,018
Ensembl chr 4:116,246,955...116,253,017
JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:23478334) RGD PMID:23478334 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248) RGD PMID:17938248 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
G Ccnb1 cyclin B1 involved_in ISO
IEA
IBA
(PMID:18195732)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18195732 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdc23 cell division cycle 23 involved_in ISO (PMID:14657031) RGD PMID:14657031 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
JBrowse link
G Cdca5 cell division cycle associated 5 involved_in ISO
IBA
(PMID:15837422)
GO_REF:0000033
RGD
GO_Central
PMID:15837422 GO_REF:0000033 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca8 cell division cycle associated 8 involved_in ISO (PMID:15260989) RGD PMID:15260989 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) RGD PMID:15843429 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cep55 centrosomal protein 55 NOT|involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Chmp1a charged multivesicular body protein 1A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436
JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452
JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:3,337,478...3,364,015
Ensembl chr11:3,337,494...3,385,181
JBrowse link
G Chmp3 charged multivesicular body protein 3 NOT|involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in IEA
ISO
GO_REF:0000107
(PMID:20616062)
Ensembl
RGD
PMID:20616062 GO_REF:0000107 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668
JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529
JBrowse link
G Chmp6 charged multivesicular body protein 6 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640
JBrowse link
G Chmp7 charged multivesicular body protein 7 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr15:44,790,983...44,806,216
Ensembl chr15:44,790,996...44,806,216
JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA
(PMID:17543862), (PMID:19995937)
GO_REF:0000107
RGD
Ensembl
PMID:17543862 PMID:19995937 GO_REF:0000107 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
JBrowse link
G Dctn2 dynactin subunit 2 involved_in ISO
IEA
(PMID:8647893)
GO_REF:0000107
RGD
Ensembl
PMID:8647893 GO_REF:0000107 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543
JBrowse link
G Eml3 EMAP like 3 involved_in ISO (PMID:18445686), (PMID:30723163) RGD PMID:18445686 PMID:30723163 NCBI chr 1:205,826,354...205,837,790
Ensembl chr 1:205,817,378...205,837,807
JBrowse link
G Eml4 EMAP like 4 involved_in ISO (PMID:25789526) RGD PMID:25789526 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:15843429) RGD PMID:15843429 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Kif18a kinesin family member 18A involved_in
acts_upstream_of_or_within
ISO (PMID:17346968)
(PMID:20981276)
RGD PMID:17346968 PMID:20981276 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
JBrowse link
G Kif22 kinesin family member 22 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15843429)
UniProt
Ensembl
RGD
PMID:15843429 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
JBrowse link
G Kif2c kinesin family member 2C involved_in ISO
ISS
(PMID:15843429)
GO_REF:0000024
RGD
UniProt
PMID:15843429 GO_REF:0000024 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kifc1 kinesin family member C1 involved_in ISO
IEA
ISS
(PMID:15843429)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15843429 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Kpnb1 karyopherin subunit beta 1 involved_in ISO
IEA
(PMID:23783028)
GO_REF:0000107
RGD
Ensembl
PMID:23783028 GO_REF:0000107 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Nudc nuclear distribution C, dynein complex regulator involved_in ISO
ISS
(PMID:25789526)
GO_REF:0000024
RGD
UniProt
PMID:25789526 GO_REF:0000024 NCBI chr 5:145,758,006...145,771,390
Ensembl chr 5:145,758,002...145,771,425
JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein NOT|involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:21224392) RGD PMID:21224392 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO
IEA
(PMID:19393617)
GO_REF:0000107
RGD
Ensembl
PMID:19393617 GO_REF:0000107 NCBI chr15:38,097,896...38,157,143
Ensembl chr15:38,097,886...38,157,140
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:18411309)
UniProt
GO_Central
Ensembl
RGD
PMID:18411309 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
JBrowse link
G Rab11a RAB11a, member RAS oncogene family involved_in ISO (PMID:24561039) RGD PMID:24561039 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog involved_in ISO (PMID:19465021) RGD PMID:19465021 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140
JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:17363900) RGD PMID:17363900 NCBI chr18:61,346,986...61,369,987 JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:28495837)
UniProt
RGD
PMID:28495837 GO_REF:0000024 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q96BD8 (PMID:28495837)
UniProt
RGD
PMID:28495837 GO_REF:0000024 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISS
ISO
GO_REF:0000024
UniProtKB:Q96BD8 (PMID:28495837)
UniProt
RGD
PMID:28495837 GO_REF:0000024 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in ISO
IBA
ISS
(PMID:19468067)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:19468067 GO_REF:0000024 GO_REF:0000033 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO
IEA
(PMID:20616062)
GO_REF:0000107
RGD
Ensembl
PMID:20616062 GO_REF:0000107 NCBI chr19:34,934,999...34,948,888
Ensembl chr19:34,934,961...34,948,887
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229
JBrowse link
G Zw10 zw10 kinetochore protein involved_in ISO (PMID:19468067) RGD PMID:19468067 NCBI chr 8:49,396,541...49,424,743
Ensembl chr 8:49,396,545...49,421,805
JBrowse link
attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cenpc centromere protein C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:15843429) RGD PMID:15843429 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 involved_in ISO
IBA
(PMID:21063390)
GO_REF:0000033
RGD
GO_Central
PMID:21063390 GO_REF:0000033 NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984
JBrowse link
G Kif2c kinesin family member 2C involved_in ISO
ISS
IEA
(PMID:23891108)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:23891108 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 involved_in ISS
ISO
IEA
GO_REF:0000024
UniProtKB:Q96BD8 (PMID:23001180), (PMID:36592928)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23001180 PMID:36592928 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in ISO
IEA
ISS
(PMID:23891108)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23891108 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO
IBA
(PMID:22581055), (PMID:23891108), (PMID:25743205), (PMID:30409912)
GO_REF:0000033
RGD
GO_Central
PMID:22581055 PMID:23891108 PMID:25743205 PMID:30409912 GO_REF:0000033 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Seh1l SEH1-like nucleoporin involved_in ISO (PMID:17363900) RGD PMID:17363900 NCBI chr18:61,346,986...61,369,987 JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:29487209), (PMID:36592928)
Ensembl
UniProt
RGD
PMID:29487209 PMID:36592928 GO_REF:0000024 GO_REF:0000107 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:29487209)
UniProt
RGD
PMID:29487209 GO_REF:0000024 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28479321), (PMID:29487209)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28479321 PMID:29487209 GO_REF:0000024 GO_REF:0000107 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
JBrowse link
lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:23891108) RGD PMID:23891108 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
microtubule plus-end directed mitotic chromosome migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpe centromere protein E involved_in ISO (PMID:25908662) RGD PMID:25908662 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
mitotic sister chromatid biorientation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISS
ISO
GO_REF:0000024
(PMID:22371557)
UniProt
RGD
PMID:22371557 GO_REF:0000024 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 involved_in ISO (PMID:17938248), (PMID:24157919) RGD PMID:17938248 PMID:24157919 NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787
JBrowse link
negative regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 involved_in ISO (PMID:30409912) RGD PMID:30409912 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
positive regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in ISO (PMID:23478334) RGD PMID:23478334 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:21242313)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21242313 GO_REF:0000024 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:23001180) RGD PMID:23001180 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO
ISS
IEA
(PMID:30409912)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:30409912 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO
IEA
(PMID:28751710)
GO_REF:0000107
RGD
Ensembl
PMID:28751710 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
regulation of attachment of mitotic spindle microtubules to kinetochore term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin-dependent kinase 1 involved_in ISO
ISS
(PMID:28479321)
GO_REF:0000024
RGD
UniProt
PMID:28479321 GO_REF:0000024 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
repair of mitotic kinetochore microtubule attachment defect term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISS
ISO
GO_REF:0000024
(PMID:22371557)
UniProt
RGD
PMID:22371557 GO_REF:0000024 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Ttk Ttk protein kinase involved_in ISO (PMID:18243099), (PMID:28441529) RGD PMID:18243099 PMID:28441529 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    cellular process 18312
      cell cycle process 1295
        mitotic cell cycle process 736
          mitotic metaphase chromosome alignment 60
            attachment of mitotic spindle microtubules to kinetochore + 22
            microtubule plus-end directed mitotic chromosome migration 1
            mitotic metaphase chromosome recapture 0
            repair of mitotic kinetochore microtubule attachment defect + 2
Path 2
Term Annotations click to browse term
  biological_process 19872
    cellular process 18312
      cellular component organization or biogenesis 7000
        cellular component organization 6747
          organelle organization 3721
            organelle fission 519
              nuclear division 461
                mitotic nuclear division 275
                  mitotic sister chromatid segregation 184
                    mitotic metaphase chromosome alignment 60
                      attachment of mitotic spindle microtubules to kinetochore + 22
                      microtubule plus-end directed mitotic chromosome migration 1
                      mitotic metaphase chromosome recapture 0
                      repair of mitotic kinetochore microtubule attachment defect + 2
paths to the root