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ONTOLOGY REPORT - ANNOTATIONS

Term:long-chain fatty acid biosynthetic process
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Accession:GO:0042759 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:exact_synonym: long-chain fatty acid anabolism;   long-chain fatty acid biosynthesis;   long-chain fatty acid formation;   long-chain fatty acid synthesis


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long-chain fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11381125 GO_REF:0000033, RGD:68727 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391 		JBrowse link
G Acsbg2 acyl-CoA synthetase bubblegum family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:1,683,846...1,715,517
Ensembl chr 9:1,683,847...1,714,518 		JBrowse link
G Acsbg3 acyl-CoA synthetase bubblegum family member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:1,715,613...1,727,637
Ensembl chr 9:1,704,674...1,727,634 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in ISO
ISS		 (PMID:20937905)
GO_REF:0000024		 RGD
UniProt		 PMID:20937905 GO_REF:0000024 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Fads1 fatty acid desaturase 1 acts_upstream_of_or_within ISO (PMID:10601301) RGD PMID:10601301 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27791009)		 UniProt
Ensembl
RGD		 PMID:27791009 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Ltc4s leukotriene C4 synthase involved_in ISO
IEA
ISS		 (PMID:27791009)
GO_REF:0000104
GO_REF:0000024		 RGD
UniProt		 PMID:27791009 GO_REF:0000024 GO_REF:0000104 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within ISO MGI:1856005 (PMID:1150661) RGD PMID:1150661 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Plp1 proteolipid protein 1 acts_upstream_of_or_within ISO MGI:1856065 (PMID:1150661) RGD PMID:1150661 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856539 (PMID:1150661)		 Ensembl
RGD		 PMID:1150661 GO_REF:0000107 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
hepoxilin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in IDA PMID:23382512 UniProt PMID:23382512 RGD:8554649 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IDA
IBA		 PMID:23382512
GO_REF:0000033		 GO_Central PMID:23382512 GO_REF:0000033, RGD:8554649 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in IDA PMID:23382512 RGD
UniProt		 PMID:15123652 PMID:23382512 RGD:5509794, RGD:8554649 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IDA
IBA		 PMID:23382512
GO_REF:0000033		 GO_Central PMID:23382512 GO_REF:0000033, RGD:8554649 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO
IBA
IDA		 (PMID:12881489), (PMID:17045234)
GO_REF:0000033
(MGI:3694035|PMID:17045234), (MGI:5488571|PMID:22832496)
PMID:23382512		 RGD
GO_Central		 PMID:12881489 PMID:17045234 PMID:22832496 PMID:23382512 GO_REF:0000033 MGI:3694035 MGI:5488571, RGD:8554649 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in ISO
ISS		 (PMID:21046276)
GO_REF:0000024		 RGD
UniProt		 PMID:21046276 GO_REF:0000024 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO
ISS		 (PMID:21046276)
GO_REF:0000024		 RGD
UniProt		 PMID:21046276 GO_REF:0000024 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
ISS		 (PMID:21046276)
GO_REF:0000024		 RGD
UniProt		 PMID:21046276 GO_REF:0000024 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
leukotriene A4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24282679), (PMID:31664810)
(MGI:6392995|PMID:31642348)		 UniProt
Ensembl
RGD		 PMID:24282679 PMID:31642348 PMID:31664810 GO_REF:0000024 GO_REF:0000107 MGI:6392995 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
lipoxin A4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(PMID:8250832)		 UniProt
RGD		 PMID:8250832 GO_REF:0000024 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3579746|PMID:15708862)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15708862 GO_REF:0000024 GO_REF:0000107 MGI:3579746 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:27145229)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:27145229 GO_REF:0000024 GO_REF:0000107 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
lipoxin B4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(PMID:8250832)		 UniProt
RGD		 PMID:8250832 GO_REF:0000024 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
palmitic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot7 acyl-CoA thioesterase 7 involved_in ISO
IEA		 (PMID:10578051)
GO_REF:0000107		 RGD
Ensembl		 PMID:10578051 GO_REF:0000107 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18196
      cellular metabolic process 9552
        cellular lipid metabolic process 1074
          fatty acid metabolic process 454
            long-chain fatty acid metabolic process 120
              long-chain fatty acid biosynthetic process 22
                (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                hepoxilin biosynthetic process 9
                jasmonic acid biosynthetic process + 0
                leukotriene A4 biosynthetic process 1
                leukotriene B4 biosynthetic process 0
                lipoxin A4 biosynthetic process 3
                lipoxin B4 biosynthetic process 1
                palmitic acid biosynthetic process 1
                resolvin biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11448
      cellular metabolic process 9552
        organic acid metabolic process 1021
          oxoacid metabolic process 1010
            carboxylic acid metabolic process 995
              monocarboxylic acid metabolic process 729
                fatty acid metabolic process 454
                  long-chain fatty acid metabolic process 120
                    long-chain fatty acid biosynthetic process 22
                      (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                      hepoxilin biosynthetic process 9
                      jasmonic acid biosynthetic process + 0
                      leukotriene A4 biosynthetic process 1
                      leukotriene B4 biosynthetic process 0
                      lipoxin A4 biosynthetic process 3
                      lipoxin B4 biosynthetic process 1
                      palmitic acid biosynthetic process 1
                      resolvin biosynthetic process + 0
paths to the root