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Gene: Asah2 (N-acylsphingosine amidohydrolase 2) Rattus norvegicus
Symbol: Asah2
Name: N-acylsphingosine amidohydrolase 2
RGD ID: 69410
Description: Exhibits dihydroceramidase activity and phytoceramidase activity. Involved in response to organic substance and sphingolipid metabolic process. Localizes to extracellular space; integral component of plasma membrane; and mitochondrion. Colocalizes with membrane raft. Orthologous to several human genes including ASAH2B (N-acylsphingosine amidohydrolase 2B); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acylsphingosine deacylase 2; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; N-CDase; NCDase; neutral ceramidase; neutral/alkaline ceramidase
Homo sapiens (human) : ASAH2 (N-acylsphingosine amidohydrolase 2)  HGNC  Alliance
Mus musculus (house mouse) : Asah2 (N-acylsphingosine amidohydrolase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Asah2 (N-acylsphingosine amidohydrolase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985247 (putative inactive neutral ceramidase B)
Canis lupus familiaris (dog) : ASAH2 (N-acylsphingosine amidohydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Asah2 (N-acylsphingosine amidohydrolase 2)
Sus scrofa (pig) : ASAH2 (N-acylsphingosine amidohydrolase 2)
Chlorocebus sabaeus (African green monkey) : ASAH2 (N-acylsphingosine amidohydrolase 2)
Heterocephalus glaber (naked mole-rat) : Asah2 (N-acylsphingosine amidohydrolase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01250,557,042 - 250,665,083 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1250,557,044 - 250,630,677 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01257,790,747 - 257,898,648 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,000,768 - 236,072,477 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11236,164,792 - 236,236,500 (-)NCBI
Celera1226,986,485 - 227,059,852 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Asah2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69410
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.