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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of CD4-positive, alpha-beta T cell activation
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Accession:GO:2000514 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.

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regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor involved_in ISO (PMID:22473704) UniProt PMID:22473704 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in ISO (PMID:22307619) UniProt PMID:22307619 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955402:2,652,020...2,685,350
Ensembl chrNW_004955402:2,652,020...2,686,117 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chrNW_004955568:365,700...372,149 JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chrNW_004955484:9,503,286...9,557,066
Ensembl chrNW_004955484:9,503,227...9,557,066 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) UniProt PMID:22473704 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chrNW_004955452:4,580,444...4,606,820
Ensembl chrNW_004955452:4,579,331...4,636,884 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in ISO (MGI:5908533|PMID:25009204) UniProt PMID:25009204 MGI:5908533 NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) UniProt PMID:24691993 NCBI chrNW_004955434:9,487,309...9,508,366
Ensembl chrNW_004955434:9,487,315...9,505,904 		JBrowse link
G Cd44 CD44 molecule (IN blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:17028180) MGI PMID:17028180 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:14973438) MGI PMID:14973438 NCBI chrNW_004955422:26,810,829...26,918,517
Ensembl chrNW_004955422:26,809,972...26,887,123 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097)
(MGI:5688819|PMID:25065622)		 UniProt PMID:20209097 PMID:25065622 MGI:5688819 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004955415:11,643,846...11,666,131
Ensembl chrNW_004955415:11,643,846...11,666,131 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) MGI PMID:15568026 NCBI chrNW_004955486:8,670,182...8,684,677 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955402:2,652,020...2,685,350
Ensembl chrNW_004955402:2,652,020...2,686,117 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:24691993)
(PMID:21383057)		 UniProt
MGI		 PMID:21383057 PMID:24691993 NCBI chrNW_004955437:19,716,466...19,743,428 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) UniProt PMID:24463518 MGI:5565031 NCBI chrNW_004955422:14,051,140...14,053,521
Ensembl chrNW_004955422:14,051,140...14,053,521 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004955524:3,399,895...3,412,018
Ensembl chrNW_004955524:3,401,642...3,411,643 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) UniProt PMID:24463518 MGI:5565031 NCBI chrNW_004955422:14,051,140...14,053,521
Ensembl chrNW_004955422:14,051,140...14,053,521 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) UniProt PMID:23169781 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il2 interleukin 2 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) MGI PMID:18792410 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955419:5,054,288...5,103,926
Ensembl chrNW_004955419:5,054,289...5,103,926 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chrNW_004955402:34,028,184...34,058,949
Ensembl chrNW_004955402:34,028,063...34,058,291 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO (PMID:23034280) MGI PMID:23034280 NCBI chrNW_004955545:1,504,656...1,519,954
Ensembl chrNW_004955545:1,503,514...1,521,003 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase like 3 involved_in ISO (MGI:5825383|PMID:28065600)
(PMID:28065600)		 UniProt PMID:28065600 MGI:5825383 NCBI chrNW_004955424:11,236,415...11,255,801
Ensembl chrNW_004955424:11,236,836...11,259,570 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chrNW_004955406:13,391,162...13,402,479 JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO (PMID:17008549) UniProt PMID:17008549 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) UniProt PMID:24463518 MGI:5565031 NCBI chrNW_004955422:14,051,140...14,053,521
Ensembl chrNW_004955422:14,051,140...14,053,521 		JBrowse link
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004955520:2,937,131...2,941,170
Ensembl chrNW_004955520:2,936,815...2,941,170 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chrNW_004955441:13,593,342...13,657,389
Ensembl chrNW_004955441:13,593,342...13,657,389 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO (PMID:15917799) MGI PMID:15917799 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G LOC102019320 mamu class II histocompatibility antigen, DR alpha chain involved_in ISO (PMID:15265931) UniProt PMID:15265931 NCBI chrNW_004955437:1,109,735...1,114,742
Ensembl chrNW_004955437:1,109,713...1,114,802 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd83 CD83 molecule acts_upstream_of_or_within ISO (PMID:15322158) MGI PMID:15322158 NCBI chrNW_004955465:676,006...692,770
Ensembl chrNW_004955465:674,168...693,353 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:17028180) MGI PMID:17028180 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (MGI:3818191|PMID:19015308) UniProt PMID:19015308 MGI:3818191 NCBI chrNW_004955458:1,733,799...1,785,591
Ensembl chrNW_004955458:1,733,883...1,784,182 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISO (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chrNW_004955442:7,321,337...7,323,109
Ensembl chrNW_004955442:7,321,337...7,323,109 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chrNW_004955545:1,504,656...1,519,954
Ensembl chrNW_004955545:1,503,514...1,521,003 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:15314074)
(PMID:8125140)		 MGI PMID:8125140 PMID:15314074 NCBI chrNW_004955411:32,270,881...32,275,236
Ensembl chrNW_004955411:32,270,881...32,275,236 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:14973438), (PMID:8125140), (PMID:9368605)
(PMID:9368605)		 MGI PMID:8125140 PMID:9368605 PMID:14973438 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:11894097), (PMID:14973438), (PMID:8125140) MGI PMID:8125140 PMID:11894097 PMID:14973438 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004955406:42,773,368...42,796,205 JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:22307619) UniProt PMID:22307619 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (MGI:3822251|PMID:18806793) UniProt PMID:18806793 MGI:3822251 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Prkcq protein kinase C theta acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894097)
(PMID:11894098)		 MGI PMID:11894097 PMID:11894098 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (PMID:17164348) BHF-UCL PMID:17164348 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (MGI:5009207|PMID:9973465) BHF-UCL PMID:9973465 MGI:5009207 NCBI chrNW_004955462:8,594,416...8,598,101 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384)
(PMID:12612578)
(PMID:16301745), (PMID:18573908)		 MGI PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004955475:10,676,592...10,680,565
Ensembl chrNW_004955475:10,676,870...10,680,517 		JBrowse link
G Klhl25 kelch like family member 25 involved_in ISO (PMID:34491895)
(MGI:6765767|PMID:34491895)		 UniProt PMID:34491895 MGI:6765767 NCBI chrNW_004955416:18,965,966...18,991,099 JBrowse link
G LOC102019320 mamu class II histocompatibility antigen, DR alpha chain involved_in ISO (PMID:28467828) UniProt PMID:28467828 NCBI chrNW_004955437:1,109,735...1,114,742
Ensembl chrNW_004955437:1,109,713...1,114,802 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO (PMID:17008549) UniProt PMID:17008549 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chrNW_004955472:1,444,598...1,446,488
Ensembl chrNW_004955472:1,444,316...1,446,490 		JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004955520:2,937,131...2,941,170
Ensembl chrNW_004955520:2,936,815...2,941,170 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894097) MGI PMID:11894097 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chrNW_004955441:13,593,342...13,657,389
Ensembl chrNW_004955441:13,593,342...13,657,389 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955402:42,919,480...42,968,873
Ensembl chrNW_004955402:42,911,649...42,972,429 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955468:2,680,934...2,688,797
Ensembl chrNW_004955468:2,680,806...2,689,155 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955427:3,350,174...3,358,609
Ensembl chrNW_004955427:3,350,174...3,360,379 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISO (PMID:28262505)
(MGI:6106706|PMID:28262505)		 UniProt PMID:28262505 MGI:6106706 NCBI chrNW_004955437:1,584,890...1,592,486
Ensembl chrNW_004955437:1,584,479...1,592,826 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (MGI:6106706|PMID:28262505) UniProt PMID:28262505 MGI:6106706 NCBI chrNW_004955495:7,959,033...7,989,216
Ensembl chrNW_004955495:7,957,510...7,988,498 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3851279|PMID:19501566) BHF-UCL PMID:19501566 MGI:3851279 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312 		JBrowse link
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcq protein kinase C theta involved_in ISO (MGI:3587418|PMID:15263025) UniProt PMID:15263025 MGI:3587418 NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in ISO (MGI:3608083|PMID:12829194) BHF-UCL PMID:12829194 MGI:3608083 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (MGI:3584076|PMID:15987782) UniProt PMID:15987782 MGI:3584076 NCBI chrNW_004955486:8,947,579...9,021,702
Ensembl chrNW_004955486:8,947,579...9,021,702 		JBrowse link
G Rara retinoic acid receptor alpha involved_in ISO (PMID:18416830) BHF-UCL PMID:18416830 NCBI chrNW_004955451:14,876,663...14,917,134
Ensembl chrNW_004955451:14,897,726...14,917,134 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:24645804) MGI PMID:24645804 NCBI chrNW_004955419:28,423,354...28,555,948
Ensembl chrNW_004955419:28,421,354...28,558,823 		JBrowse link
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (MGI:6158776|PMID:27084103) UniProt PMID:27084103 MGI:6158776 NCBI chrNW_004955403:36,989,509...37,141,188
Ensembl chrNW_004955403:36,988,811...37,142,401 		JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in ISO (PMID:12734330) UniProt PMID:12734330 NCBI chrNW_004955493:6,712,005...6,717,417
Ensembl chrNW_004955493:6,712,005...6,717,417 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:18776904) MGI PMID:18776904 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G LOC102019320 mamu class II histocompatibility antigen, DR alpha chain involved_in ISO (PMID:15322540) UniProt PMID:15322540 NCBI chrNW_004955437:1,109,735...1,114,742
Ensembl chrNW_004955437:1,109,713...1,114,802 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO (PMID:18776904) MGI PMID:18776904 NCBI chrNW_004955545:1,504,656...1,519,954
Ensembl chrNW_004955545:1,503,514...1,521,003 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12360
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          T cell activation 507
            alpha-beta T cell activation 177
              regulation of alpha-beta T cell activation 110
                regulation of CD4-positive, alpha-beta T cell activation 73
                  negative regulation of CD4-positive, alpha-beta T cell activation + 33
                  positive regulation of CD4-positive, alpha-beta T cell activation + 42
                  regulation of CD4-positive, alpha-beta T cell costimulation + 2
                  regulation of CD4-positive, alpha-beta T cell differentiation + 51
                  regulation of CD4-positive, alpha-beta T cell proliferation + 24
                  regulation of T-helper 1 cell activation + 1
                  regulation of T-helper 2 cell activation + 2
Path 2
Term Annotations click to browse term
  biological_process 12360
    biological regulation 8890
      regulation of biological process 8624
        regulation of cellular process 8177
          regulation of cell activation 567
            regulation of leukocyte activation 516
              regulation of lymphocyte activation 447
                regulation of T cell activation 326
                  regulation of alpha-beta T cell activation 110
                    regulation of CD4-positive, alpha-beta T cell activation 73
                      negative regulation of CD4-positive, alpha-beta T cell activation + 33
                      positive regulation of CD4-positive, alpha-beta T cell activation + 42
                      regulation of CD4-positive, alpha-beta T cell costimulation + 2
                      regulation of CD4-positive, alpha-beta T cell differentiation + 51
                      regulation of CD4-positive, alpha-beta T cell proliferation + 24
                      regulation of T-helper 1 cell activation + 1
                      regulation of T-helper 2 cell activation + 2
paths to the root