Il23a (interleukin 23 subunit alpha) - Rat Genome Database

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Gene: Il23a (interleukin 23 subunit alpha) Chinchilla lanigera
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Symbol: Il23a
Name: interleukin 23 subunit alpha
RGD ID: 8734119
Description: ENCODES a protein that exhibits interleukin-23 receptor binding (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of interleukin-10 production (ortholog); positive regulation of activated T cell proliferation (ortholog); PARTICIPATES IN interleukin-23 signaling pathway; ASSOCIATED WITH Amebic Liver Abscess (ortholog); Animal Toxoplasmosis (ortholog); Bovine Tuberculosis (ortholog); FOUND IN extracellular space (ortholog); interleukin-23 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: interleukin 23, alpha subunit p19; interleukin-23 subunit alpha
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,947,803 - 3,949,312 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,946,964 - 3,949,180 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
defense response to Gram-negative bacterium  (ISO)
negative regulation of interleukin-10 production  (ISO)
positive regulation of activated T cell proliferation  (ISO)
positive regulation of activation of Janus kinase activity  (ISO)
positive regulation of defense response to virus by host  (ISO)
positive regulation of granulocyte macrophage colony-stimulating factor production  (ISO)
positive regulation of interferon-gamma production  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-17 production  (ISO)
positive regulation of memory T cell differentiation  (ISO)
positive regulation of natural killer cell proliferation  (ISO)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of NK T cell activation  (ISO)
positive regulation of NK T cell proliferation  (ISO)
positive regulation of osteoclast differentiation  (ISO)
positive regulation of T cell mediated cytotoxicity  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of T-helper 1 type immune response  (ISO)
positive regulation of T-helper 17 cell lineage commitment  (ISO)
positive regulation of T-helper 17 type immune response  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
regulation of tyrosine phosphorylation of STAT protein  (ISO)
T cell proliferation  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Il23a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,947,803 - 3,949,312 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,946,964 - 3,949,180 (+)NCBIChiLan1.0ChiLan1.0
IL23A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1256,334,174 - 56,340,410 (+)EnsemblGRCh38hg38GRCh38
GRCh381256,334,159 - 56,340,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,732,668 - 56,734,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,018,930 - 55,020,461 (+)NCBINCBI36hg18NCBI36
Build 341255,018,929 - 55,020,460NCBI
Celera1256,386,015 - 56,387,546 (+)NCBI
Cytogenetic Map12q13.3NCBI
HuRef1253,771,325 - 53,772,856 (+)NCBIHuRef
CHM1_11256,700,047 - 56,701,578 (+)NCBICHM1_1
Il23a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,132,009 - 128,133,953 (-)NCBIGRCm39mm39
GRCm39 Ensembl10128,132,008 - 128,134,621 (-)Ensembl
GRCm3810128,296,140 - 128,298,084 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,296,139 - 128,298,752 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,733,196 - 127,735,140 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610127,699,089 - 127,701,033 (-)NCBImm8
Celera10130,684,464 - 130,686,407 (-)NCBICelera
Cytogenetic Map10D3NCBI
Il23a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27721,809 - 723,923 (-)NCBI
Rnor_6.0 Ensembl72,710,609 - 2,712,723 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.072,710,609 - 2,712,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,689,128 - 2,691,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,584,112 - 1,586,226 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,584,111 - 1,586,226 (-)NCBI
Celera7597,260 - 599,374 (-)NCBICelera
Cytogenetic Map7q11NCBI
IL23A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11232,828,902 - 32,830,621 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,828,902 - 32,830,617 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,575,321 - 32,576,856 (-)NCBIMhudiblu_PPA_v0panPan3
IL23A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110635,384 - 640,715 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10638,719 - 640,359 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10700,688 - 704,049 (+)NCBI
ROS_Cfam_1.010646,091 - 649,452 (+)NCBI
UMICH_Zoey_3.110623,343 - 626,704 (+)NCBI
UNSW_CanFamBas_1.010866,496 - 869,858 (+)NCBI
UU_Cfam_GSD_1.010990,220 - 993,580 (+)NCBI
Il23a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,124,372 - 58,126,957 (-)NCBI
SpeTri2.0NW_004936646743,630 - 745,998 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL23A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,732,165 - 21,734,267 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,732,416 - 21,733,981 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IL23A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,289,486 - 52,296,735 (+)NCBI
ChlSab1.1 Ensembl1152,295,106 - 52,297,244 (+)Ensembl
Vero_WHO_p1.0NW_023666037193,689,882 - 193,696,291 (-)NCBI
Il23a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480211,662,851 - 11,664,444 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016715   ⟹   ENSCLAP00000016551
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554583,947,803 - 3,949,312 (+)Ensembl
RefSeq Acc Id: XM_005397309   ⟹   XP_005397366
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554583,946,964 - 3,949,180 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005397366 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005397366   ⟸   XM_005397309
- Sequence:
RefSeq Acc Id: ENSCLAP00000016551   ⟸   ENSCLAT00000016715


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011380 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000016551 ENTREZGENE
Ensembl Transcript ENSCLAT00000016715 ENTREZGENE
NCBI Gene Il23a ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Il23a  interleukin 23 subunit alpha    interleukin 23, alpha subunit p19  Symbol and/or name change 5135510 APPROVED