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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T-helper 17 cell differentiation
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Accession:GO:2000320 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.
Synonyms:related_synonym: negative regulation of T-helper 17 cell development

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negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) UniProt PMID:24463518 MGI:5565031 NCBI chrNW_004955422:14,051,140...14,053,521
Ensembl chrNW_004955422:14,051,140...14,053,521 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) UniProt PMID:23169781 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606 		JBrowse link
G Il2 interleukin 2 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) MGI PMID:18792410 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955406:14,053,122...14,123,023
Ensembl chrNW_004955406:14,053,122...14,123,029 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955419:5,054,288...5,103,926
Ensembl chrNW_004955419:5,054,289...5,103,926 		JBrowse link
G Smad7 SMAD family member 7 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chrNW_004955402:34,028,184...34,058,949
Ensembl chrNW_004955402:34,028,063...34,058,291 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO (PMID:23034280) MGI PMID:23034280 NCBI chrNW_004955545:1,504,656...1,519,954
Ensembl chrNW_004955545:1,503,514...1,521,003 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004955452:15,306,398...15,314,959
Ensembl chrNW_004955452:15,305,775...15,314,959 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase like 3 involved_in ISO (MGI:5825383|PMID:28065600)
(PMID:28065600)		 UniProt PMID:28065600 MGI:5825383 NCBI chrNW_004955424:11,236,415...11,255,801
Ensembl chrNW_004955424:11,236,836...11,259,570 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chrNW_004955406:13,391,162...13,402,479 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    immune system process 1969
      immune effector process 530
        negative regulation of immune effector process 113
          negative regulation of T-helper cell differentiation 19
            negative regulation of T-helper 17 cell differentiation 12
              negative regulation of T-helper 17 cell lineage commitment 3
Path 2
Term Annotations click to browse term
  biological_process 12321
    cellular process 11505
      cellular developmental process 3877
        cell differentiation 3876
          cell development 2836
            hemopoiesis 919
              leukocyte differentiation 591
                mononuclear cell differentiation 482
                  lymphocyte differentiation 394
                    T cell differentiation 293
                      T cell differentiation involved in immune response 80
                        alpha-beta T cell differentiation involved in immune response 73
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 72
                            T-helper cell differentiation 70
                              regulation of T-helper cell differentiation 39
                                negative regulation of T-helper cell differentiation 19
                                  negative regulation of T-helper 17 cell differentiation 12
                                    negative regulation of T-helper 17 cell lineage commitment 3
paths to the root