Prkcz (protein kinase C zeta) - Rat Genome Database

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Gene: Prkcz (protein kinase C zeta) Chinchilla lanigera
Analyze
Symbol: Prkcz
Name: protein kinase C zeta
RGD ID: 8849840
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); phospholipase binding (ortholog); potassium channel regulator activity (ortholog); INVOLVED IN activation of phospholipase D activity (ortholog); activation of protein kinase B activity (ortholog); cell migration (ortholog); PARTICIPATES IN adenosine signaling pathway; angiotensin II signaling pathway; ceramide signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); FOUND IN apical cortex (ortholog); apical plasma membrane (ortholog); axon hillock (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,947,579 - 9,021,702 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,947,579 - 9,021,702 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of phospholipase D activity  (ISO)
activation of protein kinase B activity  (ISO)
cell migration  (ISO)
cell surface receptor signaling pathway  (ISO)
cellular protein localization  (ISO)
cellular response to insulin stimulus  (ISO)
establishment of cell polarity  (ISO)
intracellular signal transduction  (ISO)
long-term memory  (ISO)
long-term synaptic potentiation  (ISO)
membrane depolarization  (ISO)
membrane hyperpolarization  (ISO)
microtubule cytoskeleton organization  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of hydrolase activity  (ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
negative regulation of peptidyl-tyrosine phosphorylation  (ISO)
negative regulation of protein-containing complex assembly  (ISO)
neuron projection extension  (ISO)
peptidyl-serine phosphorylation  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell-matrix adhesion  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of excitatory postsynaptic potential  (ISO)
positive regulation of insulin receptor signaling pathway  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of interleukin-13 production  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of interleukin-5 production  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of protein transport  (ISO)
positive regulation of synaptic transmission  (ISO)
positive regulation of T-helper 2 cell cytokine production  (ISO)
positive regulation of T-helper 2 cell differentiation  (ISO)
protein kinase C signaling  (ISO)
protein localization to plasma membrane  (ISO)
protein phosphorylation  (ISO)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane  (ISO)
signal transduction  (ISO)
vesicle transport along microtubule  (ISO)

References


Genomics

Comparative Map Data
Prkcz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554868,947,579 - 9,021,702 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554868,947,579 - 9,021,702 (-)NCBIChiLan1.0ChiLan1.0
PRKCZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12,050,411 - 2,185,395 (+)EnsemblGRCh38hg38GRCh38
GRCh3812,050,411 - 2,185,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711,981,850 - 2,116,834 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,971,769 - 2,106,694 (+)NCBINCBI36hg18NCBI36
Build 3412,014,070 - 2,148,996NCBI
Celera1476,373 - 611,123 (-)NCBI
Cytogenetic Map1p36.33NCBI
HuRef11,259,190 - 1,392,660 (+)NCBIHuRef
CHM1_111,969,035 - 2,101,756 (+)NCBICHM1_1
Prkcz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,344,575 - 155,445,885 (-)NCBIGRCm39mm39
GRCm39 Ensembl4155,344,586 - 155,445,818 (-)Ensembl
GRCm384155,260,118 - 155,361,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,260,129 - 155,361,361 (-)EnsemblGRCm38mm10GRCm38
MGSCv374154,634,229 - 154,735,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv364154,103,920 - 154,205,191 (-)NCBImm8
Celera4157,534,125 - 157,635,425 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
Prkcz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25165,817,786 - 165,930,386 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl5165,819,466 - 165,930,367 (-)Ensembl
Rnor_6.05172,658,071 - 172,769,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5172,658,748 - 172,769,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,116,787 - 176,228,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,061,825 - 172,172,793 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15172,072,319 - 172,179,534 (-)NCBI
Celera5164,023,257 - 164,132,959 (-)NCBICelera
Cytogenetic Map5q36NCBI
PRKCZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111,918,653 - 2,046,236 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,920,219 - 2,045,855 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01763,942 - 901,531 (+)NCBIMhudiblu_PPA_v0panPan3
PRKCZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1557,012,020 - 57,113,346 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl557,012,070 - 57,112,664 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha557,089,028 - 57,190,338 (+)NCBI
ROS_Cfam_1.0557,215,092 - 57,316,595 (+)NCBI
UMICH_Zoey_3.1557,206,002 - 57,307,319 (+)NCBI
UNSW_CanFamBas_1.0557,098,518 - 57,199,838 (+)NCBI
UU_Cfam_GSD_1.0557,488,367 - 57,589,745 (+)NCBI
Prkcz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505828,082,811 - 28,162,827 (+)NCBI
SpeTri2.0NW_0049367371,303,502 - 1,383,135 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKCZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl664,068,575 - 64,163,472 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1664,073,343 - 64,159,187 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,385,685 - 58,460,767 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKCZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,367,309 - 129,502,681 (-)NCBI
ChlSab1.1 Ensembl20129,365,679 - 129,485,818 (-)Ensembl
Vero_WHO_p1.0NW_02366605433,720,444 - 33,872,633 (-)NCBI
Prkcz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248187,758,192 - 7,846,950 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008571   ⟹   ENSCLAP00000008444
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554868,947,579 - 9,021,702 (-)Ensembl
RefSeq Acc Id: XM_005404177   ⟹   XP_005404234
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554868,947,579 - 9,021,702 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504279   ⟹   XP_013359733
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554868,947,579 - 9,020,816 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404234 (Get FASTA)   NCBI Sequence Viewer  
  XP_013359733 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005404234   ⟸   XM_005404177
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013359733   ⟸   XM_013504279
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000008444   ⟸   ENSCLAT00000008571


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005910 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000008444 ENTREZGENE
Ensembl Transcript ENSCLAT00000008571 ENTREZGENE
NCBI Gene Prkcz ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Prkcz  protein kinase C zeta    protein kinase C, zeta  Symbol and/or name change 5135510 APPROVED