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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of inflammasome-mediated signaling pathway
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Accession:GO:0141087 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of an inflammasome-mediated signaling pathway.
Synonyms:exact_synonym: positive regulation of inflammasome-mediated signal transduction


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positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP2 guanylate binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 6:30,626,874...30,646,821
Ensembl chr 6:30,626,842...30,646,823 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
IDA		 (PMID:28943315) UniProt PMID:28943315 GO_REF:0000024 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IDA
IEA		 (PMID:34554188) UniProt
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CASP4 caspase 4 involved_in ISO (MGI:5780643|PMID:26173909) UniProt PMID:26173909 MGI:5780643 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IDA (PMID:23871209) UniProt PMID:23871209 NCBI chr17:5,440,917...5,468,982
Ensembl chr17:5,440,917...5,468,982 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IDA (PMID:22461501) UniProt PMID:22461501 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IDA (PMID:28943315) UniProt PMID:28943315 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA
IDA		 (PMID:28656979) Ensembl
UniProt		 PMID:28656979 GO_REF:0000107 NCBI chr19:45,251,271...45,305,284
Ensembl chr19:45,079,288...45,305,284 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:23582325) UniProt PMID:23582325 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MIR21 microRNA 21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IMP (PMID:33718825) UniProt PMID:33718825 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA
IDA		 (PMID:31189953), (PMID:36442502) Ensembl
UniProt		 PMID:31189953 PMID:36442502 GO_REF:0000107 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within IMP (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IDA
IEA		 (PMID:27043286) UniProt
Ensembl		 PMID:27043286 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:135,662,514...135,676,416
Ensembl chr 7:135,662,496...135,693,418 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within
involved_in		 IMP
IEA		 (PMID:28094437) MGI
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr15:50,493,025...50,546,666
Ensembl chr15:50,494,018...50,546,708 		JBrowse link
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IDA (PMID:38092000) UniProt PMID:38092000 NCBI chr11:57,668,114...57,701,182
Ensembl chr11:57,667,747...57,701,182 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19654
    cellular process 18268
      signal transduction 6554
        positive regulation of signal transduction 1787
          positive regulation of pattern recognition receptor signaling pathway 76
            positive regulation of inflammasome-mediated signaling pathway 24
              positive regulation of AIM2 inflammasome complex assembly 2
              positive regulation of NLRP3 inflammasome complex assembly 23
Path 2
Term Annotations click to browse term
  biological_process 19654
    response to stimulus 10167
      response to external stimulus 2939
        response to external biotic stimulus 1971
          response to other organism 1968
            defense response to other organism 1396
              defense response to symbiont 1282
                innate immune response 1089
                  regulation of innate immune response 496
                    positive regulation of innate immune response 412
                      activation of innate immune response 335
                        innate immune response-activating signaling pathway 311
                          pattern recognition receptor signaling pathway 292
                            cytoplasmic pattern recognition receptor signaling pathway 189
                              regulation of cytoplasmic pattern recognition receptor signaling pathway 130
                                regulation of inflammasome-mediated signaling pathway 48
                                  positive regulation of inflammasome-mediated signaling pathway 24
                                    positive regulation of AIM2 inflammasome complex assembly 2
                                    positive regulation of NLRP3 inflammasome complex assembly 23
paths to the root