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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of NLRP3 inflammasome complex assembly
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Accession:GO:1900227 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.
Synonyms:exact_synonym: activation of NALP3 inflammasome complex assembly;   positive regulation of NALP3 inflammasome complex assembly;   up regulation of NALP3 inflammasome complex assembly;   up regulation of NLRP3 inflammasome complex assembly;   upregulation of NALP3 inflammasome complex assembly;   upregulation of NLRP3 inflammasome complex assembly
 narrow_synonym: activation of NLRP3 inflammasome complex assembly
 related_synonym: activation of NLRP3 inflammasome activation;   positive regulation of NLRP3 inflammasome activation;   up regulation of NLRP3 inflammasome activation;   upregulation of NLRP3 inflammasome activation



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positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5488534|PMID:23502856)
GO_REF:0000107
RGD
Ensembl
PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:7387171|PMID:23246432)
(PMID:28943315)
UniProt
RGD
PMID:23246432 PMID:28943315 GO_REF:0000024 MGI:7387171 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:34554188)
(MGI:7276081|PMID:34554188)
RGD PMID:34554188 MGI:7276081 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Casp4 caspase 4 involved_in ISO (MGI:5780643|PMID:26173909) RGD PMID:26173909 MGI:5780643 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5546292|PMID:23812099)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567
JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28943315)
(MGI:6106673|PMID:28943315)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28943315 GO_REF:0000024 GO_REF:0000107 MGI:6106673 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:28656979)
(MGI:5921465|PMID:28656979)
RGD PMID:28656979 MGI:5921465 NCBI chr 1:79,075,353...79,108,882
Ensembl chr 1:79,068,904...79,108,556
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325)
(MGI:5492224|PMID:23582325)
RGD PMID:23582325 MGI:5492224 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO
GO_REF:0000024
(PMID:33718825)
UniProt
RGD
PMID:33718825 GO_REF:0000024 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
ISS
IEA
(MGI:5698271|PMID:26642356), (MGI:5751332|PMID:26814970)
GO_REF:0000024
GO_REF:0000107
(PMID:31189953), (PMID:36442502)
RGD
UniProt
Ensembl
PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 GO_REF:0000024 GO_REF:0000107 MGI:5698271 MGI:5751332 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:32514138)
GO_REF:0000107
RGD
Ensembl
PMID:32514138 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:6859739|PMID:28465465)
UniProt
RGD
PMID:28465465 GO_REF:0000024 MGI:6859739 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Prkd1 protein kinase D1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5913002|PMID:28716882)
UniProt
RGD
PMID:28716882 GO_REF:0000024 MGI:5913002 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:27043286)
(MGI:5792478|PMID:27043286)
RGD PMID:27043286 MGI:5792478 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) RGD PMID:31836654 MGI:6384515 NCBI chr 4:63,927,523...63,937,355 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5546292|PMID:23812099)
UniProt
Ensembl
RGD
PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) RGD PMID:23812099 MGI:5546292 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (MGI:5888801|PMID:28094437)
(PMID:28094437)
RGD PMID:28094437 MGI:5888801 NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      positive regulation of cellular process 6122
        positive regulation of cellular component biogenesis 570
          positive regulation of protein-containing complex assembly 218
            positive regulation of NLRP3 inflammasome complex assembly 23
Path 2
Term Annotations click to browse term
  biological_process 19553
    response to stimulus 10408
      response to biotic stimulus 1833
        response to external biotic stimulus 1790
          response to other organism 1786
            defense response to other organism 1244
              innate immune response 932
                regulation of innate immune response 429
                  positive regulation of innate immune response 352
                    activation of innate immune response 282
                      innate immune response-activating signaling pathway 256
                        pattern recognition receptor signaling pathway 244
                          cytoplasmic pattern recognition receptor signaling pathway 153
                            inflammasome-mediated signaling pathway 43
                              canonical inflammasome complex assembly 41
                                NLRP3 inflammasome complex assembly 39
                                  regulation of NLRP3 inflammasome complex assembly 36
                                    positive regulation of NLRP3 inflammasome complex assembly 23
paths to the root