Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of protein tyrosine kinase activity
go back to main search page
Accession:GO:0061097 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.


show annotations for term's descendants           Sort by:
regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERRFI1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within ISO (PMID:22975324) MGI PMID:22975324 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G ITGB3 integrin subunit beta 3 acts_upstream_of_or_within ISO (PMID:22984613) MGI PMID:22984613 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
G RAP2B RAP2B, member of RAS oncogene family involved_in ISO (PMID:19061864) UniProt PMID:19061864 NCBI chr 3:150,188,107...150,193,060
Ensembl chr 3:157,754,470...157,755,021 		JBrowse link
G RAP2C RAP2C, member of RAS oncogene family involved_in ISO (PMID:19061864) UniProt PMID:19061864 NCBI chr  X:121,334,292...121,350,658
Ensembl chr  X:131,641,193...131,656,447 		JBrowse link
negative regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLC Cbl proto-oncogene C involved_in ISO (PMID:10362357) BHF-UCL PMID:10362357 NCBI chr19:41,726,272...41,748,829 JBrowse link
G CHMP6 charged multivesicular body protein 6 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:75,415,055...75,423,279
Ensembl chr17:81,144,837...81,151,962 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 involved_in ISO PMID:17599051
(PMID:18046415)
(PMID:16648858)		 UniProt PMID:16648858 PMID:17599051 PMID:18046415 RGD:8553726 NCBI chr 1:6,771,619...6,786,217
Ensembl chr 1:8,011,848...8,033,674 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A involved_in ISO (PMID:25744720) UniProt PMID:25744720 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727 		JBrowse link
G PSEN1 presenilin 1 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:15590694) UniProt PMID:15590694 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
G TSG101 tumor susceptibility 101 involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149 		JBrowse link
G VPS25 vacuolar protein sorting 25 homolog involved_in ISO (PMID:16973552) UniProt PMID:16973552 NCBI chr17:14,538,322...14,544,573
Ensembl chr17:14,763,523...14,769,672 		JBrowse link
G ZFYVE28 zinc finger FYVE-type containing 28 involved_in ISO (PMID:19460345) UniProt PMID:19460345 NCBI chr 4:2,412,659...2,564,741
Ensembl chr 4:2,320,446...2,470,638 		JBrowse link
G ZGPAT zinc finger CCCH-type and G-patch domain containing involved_in ISO (PMID:19644445) UniProt PMID:19644445 Ensembl chr20:61,630,271...61,662,967 JBrowse link
negative regulation of non-membrane spanning protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
negative regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GGNBP2 gametogenetin binding protein 2 acts_upstream_of_or_within ISO (PMID:26764350) MGI PMID:26764350 NCBI chr17:20,491,687...20,537,516
Ensembl chr17:20,786,936...20,831,055 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr 3:50,243,926...50,248,972
Ensembl chr 3:51,479,020...51,482,551 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035)
(PMID:9151699)		 ARUK-UCL PMID:9151699 PMID:16493035 NCBI chr19:51,606,681...51,612,751 JBrowse link
G MVP major vault protein involved_in ISO (PMID:16441665) UniProt PMID:16441665 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in ISO (PMID:15539407) UniProt PMID:15539407 Ensembl chr20:61,453,386...61,462,951 JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570 		JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 involved_in ISO (PMID:17525734) UniProt PMID:17525734 NCBI chr17:18,666,094...18,742,015
Ensembl chr17:18,942,084...19,015,744 		JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:12743035), (PMID:18483258) BHF-UCL PMID:12743035 PMID:18483258 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:19574994 RGD:2317913 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G NEURL1 neuralized E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:11481456) MGI PMID:11481456 NCBI chr10:100,093,614...100,192,485 JBrowse link
positive regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI1 abl interactor 1 acts_upstream_of_or_within ISO (PMID:17101133) MGI PMID:17101133 NCBI chr10:26,863,648...26,975,376
Ensembl chr10:27,227,960...27,339,434 		JBrowse link
G AGRN agrin involved_in ISO (PMID:19376779) BHF-UCL PMID:19376779 Ensembl chr 1:936,000...966,808 JBrowse link
G CASS4 Cas scaffold protein family member 4 involved_in ISO (PMID:18256281) UniProt PMID:18256281 NCBI chr20:52,749,725...52,799,167
Ensembl chr20:54,037,046...54,084,867 		JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in ISO (PMID:7681396) UniProt PMID:7681396 NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415 		JBrowse link
G DOK7 docking protein 7 involved_in ISO (PMID:20603078) UniProt PMID:20603078 NCBI chr 4:3,613,018...3,653,764
Ensembl chr 4:3,605,185...3,628,570 		JBrowse link
G DVL2 dishevelled segment polarity protein 2 acts_upstream_of_or_within ISO (PMID:19920076) MGI PMID:19920076 NCBI chr17:7,255,241...7,264,452
Ensembl chr17:7,242,493...7,251,571 		JBrowse link
G EFNA1 ephrin A1 involved_in ISO (PMID:24217950) ARUK-UCL PMID:24217950 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228 		JBrowse link
G EGF epidermal growth factor acts_upstream_of_or_within ISO (PMID:7678348) MGI PMID:7678348 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460 		JBrowse link
G EPHA4 EPH receptor A4 involved_in ISO (PMID:24658113) ARUK-UCL PMID:24658113 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
G GPRC5B G protein-coupled receptor class C group 5 member B involved_in ISO (PMID:23169819) UniProt PMID:23169819 NCBI chr16:18,425,987...18,454,305
Ensembl chr16:19,959,077...19,985,538 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:17077323) BHF-UCL PMID:17077323 NCBI chr15:11,213,870...11,230,619 JBrowse link
G IL34 interleukin 34 acts_upstream_of_or_within ISO (PMID:26754294) ARUK-UCL PMID:26754294 Ensembl chr16:70,480,917...70,494,693 JBrowse link
G LILRA5 leukocyte immunoglobulin like receptor A5 involved_in ISO (PMID:19009525) UniProt PMID:19009525
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (PMID:18256281) UniProt PMID:18256281 NCBI chr 6:11,022,321...11,071,747
Ensembl chr 6:11,297,701...11,420,186 		JBrowse link
G NOX4 NADPH oxidase 4 involved_in ISO (PMID:27525436) ARUK-UCL PMID:27525436 NCBI chr11:84,330,362...84,496,755 JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in ISO (PMID:21216966) ParkinsonsUK-UCL PMID:21216966 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421 		JBrowse link
G RELN reelin involved_in ISO (PMID:21852430) CACAO PMID:21852430 NCBI chr 7:95,464,285...95,984,813
Ensembl chr 7:108,208,344...108,728,037 		JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 involved_in ISO (PMID:17525734) UniProt PMID:17525734 NCBI chr17:18,666,094...18,742,015
Ensembl chr17:18,942,084...19,015,744 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:22492652) AgBase PMID:22492652 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
G UNC119 unc-119 lipid binding chaperone involved_in ISO (PMID:14757743) UniProt PMID:14757743 NCBI chr17:28,223,428...28,229,361 JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within ISO (PMID:19920076) MGI PMID:19920076 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469 		JBrowse link
regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLP2 amyloid beta precursor like protein 2 acts_upstream_of_or_within ISO (PMID:17556541) MGI PMID:17556541 NCBI chr11:124,881,191...124,944,472
Ensembl chr11:128,775,329...128,847,482 		JBrowse link
G APP amyloid beta precursor protein acts_upstream_of_or_within ISO (PMID:17556541) MGI PMID:17556541 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G PSEN1 presenilin 1 acts_upstream_of_or_within ISO (PMID:17556541) MGI PMID:17556541 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17556541) MGI PMID:17556541 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of molecular function 1716
        regulation of catalytic activity 1157
          regulation of transferase activity 579
            regulation of kinase activity 514
              regulation of protein kinase activity 476
                regulation of protein tyrosine kinase activity 49
                  negative regulation of protein tyrosine kinase activity + 20
                  positive regulation of protein tyrosine kinase activity + 25
                  regulation of brain-derived neurotrophic factor-activated receptor activity 0
                  regulation of epidermal growth factor-activated receptor activity + 18
                  regulation of non-membrane spanning protein tyrosine kinase activity + 1
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        regulation of cellular process 10895
          regulation of metabolic process 6441
            regulation of macromolecule metabolic process 5912
              regulation of protein metabolic process 2015
                regulation of protein modification process 1159
                  regulation of protein phosphorylation 890
                    regulation of protein kinase activity 476
                      regulation of protein tyrosine kinase activity 49
                        negative regulation of protein tyrosine kinase activity + 20
                        positive regulation of protein tyrosine kinase activity + 25
                        regulation of brain-derived neurotrophic factor-activated receptor activity 0
                        regulation of epidermal growth factor-activated receptor activity + 18
                        regulation of non-membrane spanning protein tyrosine kinase activity + 1
paths to the root